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公开(公告)号:US6049762A
公开(公告)日:2000-04-11
申请号:US993482
申请日:1997-12-18
申请人: Alan M. Ganz , Yongdong Wang , David H. Tracy , Robert A. Hoult , Jerry E. Cahill , David A. Huppler
发明人: Alan M. Ganz , Yongdong Wang , David H. Tracy , Robert A. Hoult , Jerry E. Cahill , David A. Huppler
CPC分类号: G01J3/453 , G01J2003/2866
摘要: Standardization is achieved for FTIR spectrometric instruments that effect an intrinsic distortion in spectral information, the distortion being associated with an aperture size. An idealized function of spectral line shape is specified. With a small calibration aperture, spectral data is obtained for a basic sample having known "true" spectral data, and standard spectral data also is obtained for a standard sample. With a larger, normal sized aperture, standard spectral data is obtained again for the calibration sample. A transformation factor, that is a function of this data and the standardized function, is applied to spectral data for test samples to effect standardized information. In another embodiment, the standard sample has known true spectral data, and the basic sample is omitted. In either case, the transformation factor is applied to the sample data in logarithm form, the antilogarithm of the result effects the standardized information.
摘要翻译: 对于影响光谱信息中的固有失真的FTIR光谱仪器实现标准化,失真与孔径尺寸相关联。 规定了光谱线形状的理想化功能。 使用小的校准孔径,获得具有已知“真实”光谱数据的基本样品的光谱数据,并且还为标准样品获得标准光谱数据。 对于较大的正常尺寸的孔径,再次为校准样品获得标准光谱数据。 作为该数据和标准化函数的函数的变换因子被应用于测试样本的光谱数据以实现标准化信息。 在另一个实施例中,标准样品具有已知的真实光谱数据,并省略了基本样品。 在任一种情况下,转换因子以对数形式应用于样本数据,结果的反对数效应影响标准化信息。
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公开(公告)号:US06029115A
公开(公告)日:2000-02-22
申请号:US940575
申请日:1997-09-30
申请人: David H. Tracy , Alan M. Ganz , Yongdong Wang , David A. Huppler , Juan C. Ivaldi , Christopher B. Hanna
发明人: David H. Tracy , Alan M. Ganz , Yongdong Wang , David A. Huppler , Juan C. Ivaldi , Christopher B. Hanna
CPC分类号: G01J3/28 , G01J3/2803 , G01J3/457 , G01J2003/2866
摘要: A spectrometric instrument includes a detector with detecting subarrays on small portions of the surface. Spectral data are acquired for selected subarrays at a first time for a drift standard, and compared to a zero position to obtain first offset data. Data are acquired similarly at a second time to obtain second offset data. The offset data are utilized to obtain a spectral shift for any subarray position at any selected time. The shift is applied to a matrix model used for converting test data to compositional information. Archive data for the model is obtained in the foregoing manner, using slit scanning in the instrument to achieve sub-increments smaller than the detector pixel size, with a procedure to assure that there is an integral number of scanning steps across one pixel. The drift standard may be chemical analytes, or an optical interference element producing fringes related to spectral positions in each subarray. A procedure is used to identify the fringe peaks to spectral position, with temperature correction.
摘要翻译: 光谱测量仪器包括一个检测器,在表面的小部分具有检测子阵列。 针对漂移标准在第一时间针对所选择的子阵列采集光谱数据,并与零位置进行比较以获得第一偏移数据。 在第二时间类似地获取数据以获得第二偏移数据。 偏移数据用于在任何选定的时间获得任何子阵列位置的光谱偏移。 该转移被应用于用于将测试数据转换成组合信息的矩阵模型。 以上述方式获得用于模型的存档数据,使用仪器中的狭缝扫描来实现小于检测器像素尺寸的次增量,以确保跨越一个像素存在整数个扫描步骤的过程。 漂移标准可以是化学分析物,或者产生与每个子阵列中的光谱位置相关的条纹的光学干涉元件。 使用一个程序来确定边缘峰到光谱位置,并进行温度校正。
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公开(公告)号:US6138082A
公开(公告)日:2000-10-24
申请号:US993483
申请日:1997-12-18
IPC分类号: G01J3/02 , G01J3/28 , G01J3/45 , G01N21/27 , G01N21/35 , G01N30/62 , G01N30/74 , G01N30/86 , G01R35/00
CPC分类号: G01J3/28 , G01N21/274 , G01N30/62 , G01N2030/626 , G01N2030/743
摘要: For conversion of spectral information of an FTIR spectrometric instrument for comparison with that of a dispersion instrument, a first standard function is selected for spectral line shape for the first instrument, and a second standard function for line shape is selected for the second instrument. A conversion factor is computed for converting the first standard function to the second standard function. In ordinary operations, first spectral information is obtained with the first instrument for a first sample, and second spectral information is obtained with the second instrument for a second sample. The conversion factor is applied to the first spectral information to effect converted information, and the converted information is compared with the second spectral information. Such conversion also is applied between chromatographic instruments.
摘要翻译: 为了将FTIR光谱仪的光谱信息转换成与分散仪器相比较的光谱信息,为第一仪器的谱线形状选择第一标准函数,为第二仪器选择线形的第二标准函数。 计算用于将第一标准函数转换为第二标准函数的转换因子。 在普通操作中,用第一样品的第一仪器获得第一光谱信息,并且用第二样品的第二仪器获得第二光谱信息。 将转换因子应用于第一光谱信息以实现转换的信息,并将转换的信息与第二光谱信息进行比较。 这种转化也适用于色谱仪器。
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公开(公告)号:US5303165A
公开(公告)日:1994-04-12
申请号:US834448
申请日:1992-02-12
申请人: Alan M. Ganz , David H. Tracy , Robert A. Hoult
发明人: Alan M. Ganz , David H. Tracy , Robert A. Hoult
CPC分类号: G01J3/2803 , G01J3/28 , G01J2003/2866
摘要: A spectrometric instrument which exhibits an intrinsic profile for a sharp spectral line produces profile data for narrow spectral lines. The spectral lines are effected with a high finesse etalon of gold coated polymer. A transformation filter is computed for transforming the profile data to a gaussian profile. A wavelength calibration is combined with the filter to effect a correction matrix which is applied to sample data to generate calibrated standardized data. Iteratively a correction matrix is applied to calibration data to generate standardized calibration data which is utilized for the wavelength calibration. Calibration is effected with an optical standard, an interference etalon and a fringe formula. Etalon effective thickness is first estimated and then precisely determined so that fringe peaks calibrate wavelength.
摘要翻译: 显示锋利光谱线的固有分布的光谱仪可以产生窄谱线的谱图数据。 光谱线用金涂层聚合物的高精密标准具实现。 计算转换滤波器以将简档数据变换为高斯分布。 波长校准与滤波器组合以实现校正矩阵,其被应用于采样数据以产生校准的标准化数据。 迭代地将校正矩阵应用于校准数据以产生用于波长校准的标准化校准数据。 用光学标准,干涉标准具和边缘公式进行校准。 首先估计Etalon有效厚度,然后精确确定边缘峰值校准波长。
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公开(公告)号:US06430513B1
公开(公告)日:2002-08-06
申请号:US09479642
申请日:2000-01-07
申请人: Yongdong Wang , David H. Tracy , Paul G. Saviano , Alan M. Ganz , Koichi Nishikida , Gitesh Kumar
发明人: Yongdong Wang , David H. Tracy , Paul G. Saviano , Alan M. Ganz , Koichi Nishikida , Gitesh Kumar
IPC分类号: G01N3100
CPC分类号: A61B5/6814 , A61B5/14546 , A61B5/14553 , G01N21/49
摘要: Constituents such as oxy- and deoxy-hemoglobin are monitored non-invasively in an animal organ such as a brain with a spectrometric instrument by passing radiation through the organ. Concentrations are computed from the spectral intensities and from a statistical correlation model. To predetermine the correlation model, the procedures are effected for a plurality of organs of a same type with each organ having established concentrations of the selected constituents, and the correlation model is statistically determined from the concentrations and corresponding intensities. For more accuracy computations are normalized to path length which may be determined by utilizing several discrete wavelengths with RF modulations.
摘要翻译: 通过使辐射通过器官,通过光谱仪器在诸如脑的动物器官中非侵入性地监测诸如氧和血红蛋白的成分。 浓度从光谱强度和统计相关模型计算。 为了预先确定相关模型,对于具有确定的所选组分浓度的每个器官,对于多个相同类型的器官进行该程序,并且根据浓度和相应的强度统计地确定相关模型。 为了更准确的计算,归一化到可以通过利用具有RF调制的几个离散波长来确定的路径长度。
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公开(公告)号:US07251085B2
公开(公告)日:2007-07-31
申请号:US11460932
申请日:2006-07-28
申请人: Dar Bahatt , Jerry E. Cahill , Koichi Nishikida , Enrico G. Picozza , Paul G. Saviano , David H. Tracy , Yongdong Wang
发明人: Dar Bahatt , Jerry E. Cahill , Koichi Nishikida , Enrico G. Picozza , Paul G. Saviano , David H. Tracy , Yongdong Wang
CPC分类号: G01N21/7703 , G01N21/553
摘要: An optical resonance analysis system comprising a sensor means (60) and an illumination means (400) for generating non-monochromatic illumination. The illumination means (400) further comprises a means for generating illumination at a plurality of angles, a lens system for projecting said illumination at said plurality of angles (390) and a dispersive device (380) for dispersing said illumination at each of said plurality of angles so that there is a correlation between said plurality of angles and the wavelengths of said illumination such that a resonance condition is generated on said sensor mean (60) for all wavelengths generated by said non-monochromatic source simultaneously. The analysis system also comprises a detection means (90) for detecting the reflected or transmitted illumination. Another embodiment comprises an anamorphic imaging means (120).
摘要翻译: 一种光学共振分析系统,包括传感器装置(60)和用于产生非单色照明的照明装置(400)。 照明装置(400)还包括用于以多个角度产生照明的装置,用于以所述多个角度(390)投射所述照明的透镜系统和用于将所述照明分散在所述多个角度的分散装置(380) 的角度,使得在所述多个角度和所述照明的波长之间存在相关性,使得对于由所述非单色源同时产生的所有波长的所述传感器平均值(60)产生共振条件。 分析系统还包括用于检测反射或透射照明的检测装置(90)。 另一实施例包括变形成像装置(120)。
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公开(公告)号:US06873417B2
公开(公告)日:2005-03-29
申请号:US10425799
申请日:2003-04-28
申请人: Dar Bahatt , Jerry E. Cahill , Koichi Nishikida , Enrico G. Picozza , Paul G. Saviano , David H. Tracy , Yongdong Wang
发明人: Dar Bahatt , Jerry E. Cahill , Koichi Nishikida , Enrico G. Picozza , Paul G. Saviano , David H. Tracy , Yongdong Wang
CPC分类号: G01N21/7703 , G01N21/553
摘要: An optical resonance analysis system comprising a sensor means (60) and an illumination means (400) for generating non-monochromatic illumination. The illumination means (400) further comprises a means for generating illumination at a plurality of angles, a lens system for projecting said illumination at said plurality of angles (390) and a dispersive device (380) for dispersing said illumination at each of said plurality of angles so that there is a correlation between said plurality of angles and the wavelengths of said illumination such that a resonance condition is generated on said sensor mean (60) for all wavelengths generated by said non-monochromatic source simultaneously. The analysis system also comprises a detection means (90) for detecting the reflected or transmitted illumination. Another embodiment comprises an anamorphic imaging means (120).
摘要翻译: 一种光学共振分析系统,包括传感器装置(60)和用于产生非单色照明的照明装置(400)。 照明装置(400)还包括用于以多个角度产生照明的装置,用于以所述多个角度(390)投射所述照明的透镜系统和用于将所述照明分散在所述多个角度的分散装置(380) 的角度,使得在所述多个角度和所述照明的波长之间存在相关性,使得对于由所述非单色源同时产生的所有波长的所述传感器平均值(60)产生共振条件。 分析系统还包括用于检测反射或透射照明的检测装置(90)。 另一实施例包括变形成像装置(120)。
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公开(公告)号:US06600563B1
公开(公告)日:2003-07-29
申请号:US09486424
申请日:2000-07-17
申请人: Dar Bahatt , Jerry E. Cahill , Koichi Nishikida , Enrico G. Picozza , Paul G. Saviano , David H. Tracy , Yongdong Wang
发明人: Dar Bahatt , Jerry E. Cahill , Koichi Nishikida , Enrico G. Picozza , Paul G. Saviano , David H. Tracy , Yongdong Wang
IPC分类号: G01N2155
CPC分类号: G01N21/7703 , G01N21/553
摘要: An optical resonance analysis system comprising a sensor means (60) and an illumination means (400) for generating non-monochromatic illumination. The illumination means (400) further comprises a means for generating illumination at a plurality of angles, a lens system for projecting said illumination at said plurality of angles (390) and a dispersive device (380) for dispersing said illumination at each of said plurality of angles so that there is a correlation between said plurality of angles and the wavelengths of said illumination such that a resonance condition is generated on said sensor mean (60) for all wavelengths generated by said non-monochromatic source simultaneously. The analysis system also comprises a detection means (90) for detecting the reflected or transmitted illumination. Another embodiment comprises an anamorphic imaging means (120).
摘要翻译: 一种光学共振分析系统,包括传感器装置(60)和用于产生非单色照明的照明装置(400)。 照明装置(400)还包括用于以多个角度产生照明的装置,用于以所述多个角度(390)投射所述照明的透镜系统和用于将所述照明分散在所述多个角度的分散装置(380) 的角度,使得在所述多个角度和所述照明的波长之间存在相关性,使得对于由所述非单色源同时产生的所有波长的所述传感器平均值(60)产生共振条件。 分析系统还包括用于检测反射或透射照明的检测装置(90)。 另一实施例包括变形成像装置(120)。
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公开(公告)号:US5526451A
公开(公告)日:1996-06-11
申请号:US324560
申请日:1994-10-18
申请人: Jerry E. Cahill , David H. Tracy
发明人: Jerry E. Cahill , David H. Tracy
CPC分类号: G02B6/3604 , G01N21/253 , G01N2201/0407 , G01N2201/084 , G02B6/32 , G02B6/4214
摘要: In a spectrophotometer, each of a plurality of source optical fibers is selectively receptive of source radiation and carries the radiation to a corresponding selected liquid sample cell. A corresponding return optical fiber returns transmitted radiation from the sample to a polychromator. For selecting a sample, a switching member holds exposed ends of the optical fibers on a circle coaxial with an axle for rotating to selected positions. Respective optical trains in the instrument direct radiation into and out of the selected pair of fibers. The diameter of a source aperture, the spacing of the aperture from the radiation source, and the source area define a source etendue. The optical fibers have a fiber etendue substantially the same as the source etendue.
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公开(公告)号:US5481631A
公开(公告)日:1996-01-02
申请号:US201848
申请日:1994-02-25
申请人: Jerry E. Cahill , David H. Tracy
发明人: Jerry E. Cahill , David H. Tracy
CPC分类号: G02B6/352 , G02B5/122 , G02B6/355 , G02B6/3574
摘要: An optical switch includes a primary optical fiber terminating in a primary window, and a plurality of secondary optical fibers each terminating in a secondary window facing in the same direction as and spaced laterally from the primary window. A primary lens on a primary axis has a focal point positioned on the axis at the central window. Each of a plurality of secondary lenses has an axis and a focal point positioned on such axis at a secondary window. The secondary axes are parallel to and equidistant from the primary axis. A retroreflector is spaced from the lenses oppositely from each window and has an optical axis centered parallel to the primary axis midway between the primary axis and any of the secondary fibers. A stepper motor rotates the retroreflector about the primary axis to each of a plurality of selected positions to provide optical switching for light transmission between the primary fiber and any selected secondary fiber.
摘要翻译: 光开关包括终端在主窗口中的主光纤,以及多个次光纤,每个次光纤终止于与主窗口相同的方向和与主窗口横向相隔的次窗口。 主轴上的主透镜具有位于中心窗口的轴上的焦点。 多个次级透镜中的每一个具有在次视窗处定位在该轴上的轴和焦点。 次轴与主轴平行并等距离。 后向反射器与透镜相反地与每个窗口间隔开,并且具有在主轴线和任何次级光纤之间的中间平行于主轴线的光轴。 步进电机将回射器围绕主轴旋转到多个选定位置中的每一个,以提供用于主光纤和任何选定次级光纤之间的光传输的光学切换。
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