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    Piperidine Compounds Useful as Malonyl-CoA Decarboxylase Inhibitors
    3.
    发明申请
    Piperidine Compounds Useful as Malonyl-CoA Decarboxylase Inhibitors 有权
    可用作丙二酰辅酶A脱羧酶抑制剂的哌啶化合物

    公开(公告)号：US20090124660A1

    公开(公告)日：2009-05-14

    申请号：US12245558

    申请日：2008-10-03

    申请人： Jie Fei Cheng ,  Mi Chen ,  Thomas Arrhenius ,  Mark E. Wilson ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

    发明人： Jie Fei Cheng ,  Mi Chen ,  Thomas Arrhenius ,  Mark E. Wilson ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

    IPC分类号： A61K31/454 ,  C07D417/12

    CPC分类号： C07D417/12 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/55

    摘要： The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.

    摘要翻译： 本发明提供了使用结构I所示化合物的方法，含有该化合物的药物组合物，以及预防，治疗和治疗由MCD抑制调节的代谢疾病和疾病的方法。 本发明公开的化合物可用于预防，管理和治疗涉及丙二酰辅酶A调节的葡萄糖/脂肪酸代谢途径的疾病。 特别地，这些化合物和含有它们的药物组合物在心血管疾病，糖尿病，癌症和肥胖症的预防，治疗和治疗中被指出。

    Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors
    4.
    发明授权
    Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors 有权
    可用作丙二酰辅酶A脱羧酶抑制剂的哌啶化合物

    公开(公告)号：US08080665B2

    公开(公告)日：2011-12-20

    申请号：US12245558

    申请日：2008-10-03

    申请人： Jie Fei Cheng ,  Mi Chen ,  Thomas Arrhenius ,  Mark E. Wilson ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

    发明人： Jie Fei Cheng ,  Mi Chen ,  Thomas Arrhenius ,  Mark E. Wilson ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

    IPC分类号： A61K31/4468 ,  C07D211/58

    CPC分类号： C07D417/12 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/55

    摘要： The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.

    摘要翻译： 本发明提供了使用结构I所示化合物的方法，含有该化合物的药物组合物，以及预防，治疗和治疗由MCD抑制调节的代谢疾病和疾病的方法。 本发明公开的化合物可用于预防，管理和治疗涉及丙二酰辅酶A调节的葡萄糖/脂肪酸代谢途径的疾病。 特别地，这些化合物和含有它们的药物组合物在心血管疾病，糖尿病，癌症和肥胖症的预防，治疗和治疗中被指出。

    Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors
    5.
    发明授权
    Piperidine compounds useful as malonyl-CoA decarboxylase inhibitors 失效
    可用作丙二酰辅酶A脱羧酶抑制剂的哌啶化合物

    公开(公告)号：US07449482B2

    公开(公告)日：2008-11-11

    申请号：US10900705

    申请日：2004-07-28

    申请人： Jie Fei Cheng ,  Mi Chen ,  Thomas Arrhenius ,  Mark E. Wilson ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

    发明人： Jie Fei Cheng ,  Mi Chen ,  Thomas Arrhenius ,  Mark E. Wilson ,  Gary D. Lopaschuk ,  Jason R. Dyck ,  Rossy Serafimov

    IPC分类号： A61K31/4468

    CPC分类号： C07D417/12 ,  A61K31/454 ,  A61K31/4545 ,  A61K31/55

    摘要： The present invention provides methods for the use of compounds as depicted by structure I, pharmaceutical compositions containing the same, and methods for the prophylaxis, management and treatment of metabolic diseases and diseases modulated by MCD inhibition. The compounds disclosed in this invention are useful for the prophylaxis, management and treatment of diseases involving in malonyl-CoA regulated glucose/fatty acid metabolism pathway. In particular, these compounds and pharmaceutical composition containing the same are indicated in the prophylaxis, management and treatment of cardiovascular diseases, diabetes, cancer and obesity.

    摘要翻译： 本发明提供了使用结构I所示化合物的方法，含有该化合物的药物组合物，以及预防，治疗和治疗由MCD抑制调节的代谢疾病和疾病的方法。 本发明公开的化合物可用于预防，管理和治疗涉及丙二酰辅酶A调节的葡萄糖/脂肪酸代谢途径的疾病。 特别地，这些化合物和含有它们的药物组合物在心血管疾病，糖尿病，癌症和肥胖症的预防，治疗和治疗中被指出。

    Automatically populating content anticipating failure
    6.
    发明授权
    Automatically populating content anticipating failure 有权
    自动填充预期故障的内容

    公开(公告)号：US08863206B2

    公开(公告)日：2014-10-14

    申请号：US13210112

    申请日：2011-08-15

    申请人： Mi Chen

    发明人： Mi Chen

    IPC分类号： H04N7/173 ,  H04N21/24 ,  H04L29/14 ,  H04H40/09 ,  H04H20/40 ,  H04N21/4627 ,  H04H20/42 ,  G06F11/00 ,  H04H60/06 ,  H04N21/254 ,  H04L29/08 ,  H04N21/262

    CPC分类号： G06F11/004 ,  H04H20/40 ,  H04H20/42 ,  H04H40/09 ,  H04H60/06 ,  H04L67/325 ,  H04L69/40 ,  H04N21/2402 ,  H04N21/2541 ,  H04N21/26208 ,  H04N21/4627

    摘要： A content provider computing device that transmits content to receivers at scheduled air times receives information regarding conditions relating to the transmissions. The computing device also receives data regarding content that a receiver will record. The computing device evaluates the information and compares it with the data to determine that there is a risk of interrupted transmission. As a result, the computing device transmits the content to the receiver prior to the scheduled air time. The conditions may include weather conditions, power outage conditions, and/or any other conditions that may affect transmission. In various implementations, the computing device may include content controls prior to transmission that prevent the content from being accessed prior to specified times. In some cases, the content control may prevent all access. In other cases, the content control may prevent some kinds of access to the instance of content prior to particular times and allow others.

    摘要翻译： 内容提供商计算设备，其在预定的时间间隔内向接收者发送内容，接收关于与传输相关的条件的信息。 计算设备还接收关于接收机将记录的内容的数据。 计算设备评估信息并将其与数据进行比较，以确定存在中断传输的风险。 结果，计算设备在预定的空中时间之前将内容发送到接收机。 条件可能包括天气状况，停电条件和/或可能影响传输的任何其他条件。 在各种实现中，计算设备可以包括传输之前的内容控制，以防止在指定时间之前访问内容。 在某些情况下，内容控制可能会阻止所有访问。 在其他情况下，内容控制可以在特定时间之前阻止对内容实例的某种访问，并允许其他内容。

    Apparatus And Methods For Dynamically Optimizing Recording Schedules
    7.
    发明申请
    Apparatus And Methods For Dynamically Optimizing Recording Schedules 审中-公开
    用于动态优化记录时间表的设备和方法

    公开(公告)号：US20120224834A1

    公开(公告)日：2012-09-06

    申请号：US13037620

    申请日：2011-03-01

    申请人： Mi Chen ,  Mark Templeman ,  Seth Byerley ,  Anthony Raymond Piro

    发明人： Mi Chen ,  Mark Templeman ,  Seth Byerley ,  Anthony Raymond Piro

    IPC分类号： H04N5/761 ,  H04N5/76

    CPC分类号： H04N5/765 ,  H04N5/76 ,  H04N5/782 ,  H04N21/4334 ,  H04N21/4583 ,  H04N21/47214 ,  H04N21/4882

    摘要： In embodiments disclosed herein, television recording schedules are automatically adjusted in a digital video recording system. In at least one embodiment, the digital video recording system receives a first request to record a first program at the digital video recording system and a second recording request to record a second program at the digital video recording system. The system determines that there are insufficient resources to fulfill both the first and second recording requests. The system may set an open recording request for at least one of the first and second programs, which seeks additional scheduling data corresponding to at least one of the programs. Subsequent additional data may be received to fulfill the open recording request. In some embodiments, recording requests may be automatically rescheduled to more optimal recording times.

    摘要翻译： 在本文公开的实施例中，在数字视频记录系统中自动调整电视录像时间表。 在至少一个实施例中，数字视频记录系统接收在数字视频记录系统处记录第一节目的第一请求和在数字视频记录系统处记录第二节目的第二记录请求。 系统确定没有足够的资源来满足第一和第二记录请求。 系统可以为第一和第二程序中的至少一个设置开放记录请求，该请求寻求与至少一个程序相对应的附加调度数据。 可以接收随后的附加数据以满足开放记录请求。 在一些实施例中，记录请求可以被自动重新安排到更优​​化的记录时间。