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    Composite material, in particular a dental filling material, ultrasonic curing of dental filing materials, and a population of zirconia particles
    1.
    发明授权
    Composite material, in particular a dental filling material, ultrasonic curing of dental filing materials, and a population of zirconia particles 有权
    复合材料，特别是牙科填充材料，牙科用填充材料的超声波固化，以及一组氧化锆颗粒

    公开(公告)号：US09095508B2

    公开(公告)日：2015-08-04

    申请号：US12929964

    申请日：2011-02-28

    申请人： Alexander Van Lelieveld ,  Kristoffer Almdal ,  Søren Linderoth ,  Bent Sørensen

    发明人： Alexander Van Lelieveld ,  Kristoffer Almdal ,  Søren Linderoth ,  Bent Sørensen

    IPC分类号： A61K6/083 ,  A61K6/00 ,  A61K6/09

    CPC分类号： A61K6/0073 ,  A61K6/0002 ,  A61K6/083 ,  A61K6/09 ,  C08L33/10 ,  C08L75/16

    摘要： Example embodiments relate to a composite material exhibiting a low or even negligible volumetric shrinkage upon curing, or even a small expansion (e.g. up to 0.5%), in particular composite materials in the form of dental filling materials. Example embodiments also relate to a method of controlling volumetric shrinkage of a composite material upon curing, and to a method of reconstructing a tooth. Example embodiments also relate to ultrasonic curing of dental filling materials. Example embodiments further relate to a population of zirconia particles and methods for preparing such zirconia particles (e.g. zirconia in the tetragonal phase or zirconia in the cubic phase). The martensitic transformation of the filler ingredients is, e.g., triggered by application of ultrasound or by a chemical trigger.

    摘要翻译： 示例性实施方案涉及在固化时表现出低甚至可忽略的体积收缩率，或甚至小的膨胀（例如高达0.5％），特别是牙科填充材料形式的复合材料的复合材料。 示例性实施例还涉及在固化时控制复合材料的体积收缩的方法以及重建牙齿的方法。 示例性实施例还涉及牙科填充材料的超声波固化。 示例性实施方案进一步涉及氧化锆颗粒群和制备这种氧化锆颗粒（例如在立方相中的四方相或氧化锆中的氧化锆）的方法。 填料成分的马氏体转变例如通过施加超声波或通过化学触发来触发。

    Composite material, in particular a dental filling material, ultrasonic curing of dental filling materials, and a population of zirconia particles
    2.
    发明申请
    Composite material, in particular a dental filling material, ultrasonic curing of dental filling materials, and a population of zirconia particles 有权
    复合材料，特别是牙科填充材料，牙科填充材料的超声波固化以及一组氧化锆颗粒

    公开(公告)号：US20110152400A1

    公开(公告)日：2011-06-23

    申请号：US12929964

    申请日：2011-02-28

    申请人： Alexander Van Lelieveld ,  Kristoffer Almdal ,  Søren Linderoth ,  Bent Sørensen

    发明人： Alexander Van Lelieveld ,  Kristoffer Almdal ,  Søren Linderoth ,  Bent Sørensen

    IPC分类号： A61K6/087 ,  C01G25/02

    CPC分类号： A61K6/0073 ,  A61K6/0002 ,  A61K6/083 ,  A61K6/09 ,  C08L33/10 ,  C08L75/16

    摘要： Example embodiments relate to a composite material exhibiting a low or even negligible volumetric shrinkage upon curing, or even a small expansion (e.g. up to 0.5%), in particular composite materials in the form of dental filling materials. Example embodiments also relate to a method of controlling volumetric shrinkage of a composite material upon curing, and to a method of reconstructing a tooth. Example embodiments also relate to ultrasonic curing of dental filling materials. Example embodiments further relate to a population of zirconia particles and methods for preparing such zirconia particles (e.g. zirconia in the tetragonal phase or zirconia in the cubic phase). The martensitic transformation of the filler ingredients is, e.g., triggered by application of ultrasound or by a chemical trigger.

    摘要翻译： 示例性实施方案涉及在固化时表现出低甚至可忽略的体积收缩率，或甚至小的膨胀（例如高达0.5％），特别是牙科填充材料形式的复合材料的复合材料。 示例性实施例还涉及在固化时控制复合材料的体积收缩的方法以及重建牙齿的方法。 示例性实施例还涉及牙科填充材料的超声波固化。 示例性实施方案进一步涉及氧化锆颗粒群和制备这种氧化锆颗粒（例如在立方相中的四方相或氧化锆中的氧化锆）的方法。 填料成分的马氏体转变例如通过施加超声波或通过化学触发来触发。

    Composite Material Comprising A Water-Or Acid-Releasing Agent
    3.
    发明申请
    Composite Material Comprising A Water-Or Acid-Releasing Agent 审中-公开
    复合材料包含水或酸释放剂

    公开(公告)号：US20100016465A1

    公开(公告)日：2010-01-21

    申请号：US12225065

    申请日：2007-03-13

    申请人： Alexander Van Lelieveld ,  Mette Skovgaard Nielsen ,  Kristoffer Almdal ,  Søren Linderoth

    发明人： Alexander Van Lelieveld ,  Mette Skovgaard Nielsen ,  Kristoffer Almdal ,  Søren Linderoth

    IPC分类号： A61K6/08

    CPC分类号： A61K6/09 ,  A61K6/0073 ,  A61K6/083 ,  A61L27/446 ,  C08L33/00 ,  C08L75/16

    摘要： The present invention discloses a composite material comprising one or more fillers and a polymerizable resin base, wherein said one or more fillers comprise at least one filler ingredient, said filler ingredient(s) being present in a metastable first phase and being able to undergo a martensitic transformation to a stable second phase, the volume ratio between said stable second phase and said metastable first phase of said filler ingredient(s) being at least 1.005, and wherein said material further comprises one or more water- or acid- releasing agents; as well as a corresponding method of controlling the volumetric shrinkage of a composite material upon curing.

    摘要翻译： 本发明公开了一种包含一种或多种填料和可聚合树脂基质的复合材料，其中所述一种或多种填料包含至少一种填料成分，所述填料成分存在于亚稳态第一相中并能够经历 马氏体转化为稳定的第二相，所述稳定的第二相和所述填料成分的所述亚稳态第一相之间的体积比为至少1.005，并且其中所述材料还包含一种或多种水或酸释放剂; 以及在固化时控制复合材料的体积收缩的相应方法。

    Ultrasonic Curing of Dental Filling Materials
    4.
    发明申请
    Ultrasonic Curing of Dental Filling Materials 审中-公开
    牙科填充材料超声波固化

    公开(公告)号：US20080119585A1

    公开(公告)日：2008-05-22

    申请号：US11547677

    申请日：2005-04-14

    申请人： Alexander Van Lelieveld ,  Kristoffer Almdal ,  Soren Linderoth ,  Bent Sorensen

    发明人： Alexander Van Lelieveld ,  Kristoffer Almdal ,  Soren Linderoth ,  Bent Sorensen

    IPC分类号： A61K6/08

    CPC分类号： A61K6/0073 ,  A61K6/0002 ,  A61K6/083 ,  A61K6/09 ,  C08L33/10 ,  C08L75/16

    摘要： The present invention relates to a composite material exhibiting a low or even negligible volumetric shrinkage upon curing, or even a small expansion (e.g. up to 0.5%), in particular composite materials in the form of dental filling materials. The present invention also relates to a method of controlling volumetric shrinkage of a composite material upon curing, and to a method of reconstructing a tooth. The present invention also relates to ultrasonic curing of dental filling materials. The present invention further relates to a population of zirconia particles and methods for preparing such zirconia particles (e.g. zirconia in the tetragonal phase or zirconia in the cubic phase). The martensitic transformation of the filler ingredients is, e.g., triggered by application of ultrasound or by a chemical trigger.

    摘要翻译： 本发明涉及一种复合材料，其在固化时表现出低或甚至可忽略的体积收缩率，或甚至小的膨胀（例如高达0.5％），特别是牙科填充材料形式的复合材料。 本发明还涉及一种在固化时控制复合材料的体积收缩率的方法以及重建牙齿的方法。 本发明还涉及牙科填充材料的超声波固化。 本发明还涉及氧化锆颗粒群和制备这种氧化锆颗粒（例如立方相中的四方相或氧化锆中的氧化锆）的方法。 填料成分的马氏体转变例如通过施加超声波或通过化学触发来触发。

    Grafted cross-linked polyolefin substrates for peptide synthesis and assays
    5.
    发明授权
    Grafted cross-linked polyolefin substrates for peptide synthesis and assays 失效
    用于肽合成和测定的接枝交联聚烯烃底物

    公开(公告)号：US5886104A

    公开(公告)日：1999-03-23

    申请号：US569255

    申请日：1995-12-18

    申请人： Walther Batsberg Pedersen ,  Kristoffer Almdal ,  Lars Winther ,  Rolf Henrik Berg

    发明人： Walther Batsberg Pedersen ,  Kristoffer Almdal ,  Lars Winther ,  Rolf Henrik Berg

    IPC分类号： C07K1/04 ,  C08F8/00 ,  C08F255/02 ,  G01N33/545 ,  C12Q1/00

    CPC分类号： G01N33/545 ,  C07K1/045 ,  C08F255/02 ,  C08F8/00 ,  Y10S977/736

    摘要： A solid support for the solid-phase synthesis of peptides or proteins in high yield and in high purity, suited both to the synthesis of a single peptide or protein and to the parallel and substantially simultaneous synthesis of a plurality thereof, is based on a cross-linked polyolefin, especially polyethylene, substrate, the cross-linking having been obtained by irradiation with high energy electrons or .gamma. radiation or treatment with organic peroxide such as benzoyl peroxide, to which substrate are grafted polymer chains such as polystyrene chains which are functionalized with a chemical functionality facilitating the formation of an anchoring linkage between the polymer moiety and another chemical species. The solid support is also suited for use in solid-phase biosystems, notably bioassays, such as immunoassays, DNA hybridization assays or PCR amplification. The grafted chains may bear substituents which are such that the polymer-grafted cross-linked polyolefin substrate is swellable by water or aqueous media, in other words, hydrophilic, which makes the solid support particularly well suited for assays of the ELISA type.

    摘要翻译： PCT No.PCT / DK94 / 00245 Sec。 371 1995年12月18日第 102（e）1995年12月18日，PCT PCT。1994年6月20日PCT公布。 公开号WO95 / 00533 日期1995年1月5日固体支持以高产率和高纯度固相合成肽或蛋白质，适合单一肽或蛋白质的合成以及其多个平行且基本上同时合成的固相合成， 基于交联聚烯烃，特别是聚乙烯基材，通过用高能电子或γ辐射照射获得的交联或用有机过氧化物如过氧化苯甲酰处理得到的交联物，其中底物是聚合物链如聚苯乙烯 链，其被化学功能官能化，有助于在聚合物部分和另一种化学物质之间形成锚定连接。 固体支持物也适用于固相生物系统，特别是生物测定，如免疫测定，DNA杂交测定或PCR扩增。 接枝的链可以带有取代基，使得聚合物接枝的交联聚烯烃底物可以通过水或水性介质溶胀，换句话说是亲水的，这使得固体支持物特别适合于ELISA类型的测定。

    Miscible polyolefin blends
    8.
    发明授权
    Miscible polyolefin blends 失效
    可混溶聚烯烃共混物

    公开(公告)号：US5955546A

    公开(公告)日：1999-09-21

    申请号：US7975

    申请日：1998-01-16

    申请人： Frank S. Bates ,  Jeffrey H. Rosedale ,  Mark F. Schulz ,  Kristoffer Almdal

    发明人： Frank S. Bates ,  Jeffrey H. Rosedale ,  Mark F. Schulz ,  Kristoffer Almdal

    IPC分类号： C08L23/00 ,  C08C19/02 ,  C08L23/02 ,  C08L23/04 ,  C08L23/10 ,  C08L23/12 ,  C08L23/26 ,  C08L25/06 ,  C08L53/00 ,  C08L53/02

    CPC分类号： C08L25/06 ,  C08C19/02 ,  C08L23/02 ,  C08L23/04 ,  C08L23/10 ,  C08L23/12 ,  C08L53/00 ,  C08L53/02

    摘要： The invention relates to melt-miscible polyolefin blends, and a process for preparing the melt-miscible blends, of two or more polyolefins. Matching, within defined limits, the segment length of a modifying polyolefin with the segment length of a primary polyolefin, such as polypropylene or an ethylene/alpha-olefin copolymer, provides blends of the "matched" components which blends were heretofore unknown to be melt-miscible. A broad range of polyolefin blend compositions, and of polyolefin blends containing other polymers made compatible or dispersible with the polyolefin blend compositions, are defined, all of the blend compositions having at least one melt-miscible polyolefin phase.

    摘要翻译： 本发明涉及熔体可混溶的聚烯烃共混物，以及一种制备两种或更多种聚烯烃的熔融混溶共混物的方法。 在限定的限度内，与主要聚烯烃（如聚丙烯或乙烯/α-烯烃共聚物）的链段长度的改性聚烯烃的链段长度匹配提供了“匹配”组分的共混物，这些共混物迄今为止未知是熔体 可混合 定义了宽范围的聚烯烃共混组合物和含有与聚烯烃共混物组合物相容或可分散的其它聚合物的聚烯烃共混物，所有共混组合物都具有至少一个熔融混溶聚烯烃相。