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    Hybrid implantable cochlear stimulator hearing aid system
    1.
    发明授权
    Hybrid implantable cochlear stimulator hearing aid system 有权
    混合植入式耳蜗刺激助听器系统

    公开(公告)号：US06754537B1

    公开(公告)日：2004-06-22

    申请号：US09979804

    申请日：2001-11-13

    申请人： William Vanbrooks Harrison ,  Janusz A. Kuzma ,  Alfred E. Mann ,  Thomas J. Balkany

    发明人： William Vanbrooks Harrison ,  Janusz A. Kuzma ,  Alfred E. Mann ,  Thomas J. Balkany

    IPC分类号： A61N118

    CPC分类号： A61N1/36036 ,  A61N1/0541

    摘要： A hybrid cochlear implant hearing aid sytem (10) provides low frequency acoustic energy boost, if needed, and high frequency direct neural stimulation. Tinnitus suppression may also be provided. The neurons responsible for sensing high frequency sounds are located at the basal end of the cochlea. A short basal electrode (52) that extends into the cochlea only at the basal region allows direct stimulation of these neurons by an appropriately-controlled cochlear stimulator (50). The basal electrode array typically has from four to eight electrode contacts (54). The design of the electrode array allows the surgeon to place the array using minimally invasive surgical techniques and requires no cochleostomy. The electrode array is thin, and can typically be inserted directly through the round window membrane to make contact with, or to be positioned in close proximity to, the modiolus wall in the basal region of the cochlea. The hybrid implantable cochlear stimulator and hearing aid system relies primarily on the cochlear stimulator portion of the system for being able to sense high frequency sounds, and relies primarily on normal hearing processes, or other acoustic boosting devices and systems, for being able to sense lower frequency sounds.

    摘要翻译： 混合耳蜗植入式助听器系统（10）提供低频声能增强，如果需要，以及高频直接神经刺激。 也可以提供耳鸣抑制。 负责感测高频声音的神经元位于耳蜗的基端。 仅在基底区域延伸到耳蜗的短基底电极（52）允许通过适当控制的耳蜗刺激器（50）直接刺激这些神经元。 基极电极阵列通常具有四至八个电极触点（54）。 电极阵列的设计允许外科医生使用微创手术技术来放置阵列，并且不需要耳蜗造口术。 电极阵列是薄的，并且通常可以直接插入通过圆窗膜以与耳蜗的基底区域中的闭孔壁接触或靠近位置。 混合植入式耳蜗刺激器和助听器系统主要依赖于系统的人工耳蜗刺激器部分，以便能够感测高频声音，并且主要依赖于正常听力过程或其他声学增强装置和系统，以便能够感测较低频 频率声音。

    Inflatable cochlear electrode array and method of making same
    2.
    发明授权
    Inflatable cochlear electrode array and method of making same 失效
    充气耳蜗电极阵列及其制作方法

    公开(公告)号：US06266568B1

    公开(公告)日：2001-07-24

    申请号：US09300800

    申请日：1999-04-27

    申请人： Alfred E. Mann ,  Thomas H. R. Lenarz ,  Janusz A. Kuzma ,  William Vanbrooks Harrison

    发明人： Alfred E. Mann ,  Thomas H. R. Lenarz ,  Janusz A. Kuzma ,  William Vanbrooks Harrison

    IPC分类号： A61N104

    CPC分类号： A61N1/0541

    摘要： An inflatable cochlear electrode array adapted for insertion into a human cochlear includes a flexible carrier on which a multiplicity of spaced-apart electrode contacts are carried, preferably along one side, e.g., a medial side, of the carrier. The flexible carrier also includes an inflatable compartment or section. In one embodiment, the inflatable section is located at the distal tip of the electrode array on a side of the flexible carrier that is opposite the electrode contacts. In another embodiment, the inflatable compartment or section is located along at least one half of the full length of the flexible carrier, forming a spine. In either embodiment, the electrode is readily inserted into the cochlea to a desired depth while the inflatable compartment or section remains in a deflated state. Thereafter, a desired modiolus-hugging position is achieved by inflating the inflatable compartment or section by injecting therein a suitable biocompatible fluid. A method of making an inflatable cochlear electrode is also disclosed.

    摘要翻译： 适于插入到人类耳蜗中的充气耳蜗电极阵列包括柔性载体，其上承载有多个间隔开的电极触点，优选地沿载体的一侧，例如内侧。 柔性载体还包括可充气的隔室或部分。 在一个实施例中，可充气部分位于与电极接触件相对的柔性载体侧上的电极阵列的远端。 在另一个实施例中，可充气隔室或部分沿柔性载体的全长的至少一半定位，形成脊柱。 在任一实施例中，电极容易地插入耳蜗到期望的深度，同时可充气隔间或部分保持在放气状态。 此后，通过在其中注射合适的生物相容性流体来使充气室或部分膨胀来实现所需的夹层位置。 还公开了制造充气耳蜗电极的方法。

    Hybrid multi-function electrode array
    3.
    发明申请
    Hybrid multi-function electrode array 审中-公开
    混合多功能电极阵列

    公开(公告)号：US20100331913A1

    公开(公告)日：2010-12-30

    申请号：US11261432

    申请日：2005-10-28

    申请人： Alfred E. Mann ,  William Vanbrooks Harrison

    发明人： Alfred E. Mann ,  William Vanbrooks Harrison

    IPC分类号： A61N1/05

    CPC分类号： A61N1/0541 ,  A61N1/36036

    摘要： A hybrid electrode array includes a basal array section and a distal array section. The basal array section is configured to provide high frequency stimulation. The basal array section is configured to extend into the cochlea up to a region where electrical stimulation provides recovery for high frequency loss. The distal array section is configured to be attached to a distal tip of the basal array section and is configured to extend into the cochlear to a region where electrical stimulation provides recovery for middle to low frequency hearing loss. For progressive hearing loss treatment, the distal array section is not activated during initial stages of hearing loss allowing the patient to rely on a combination of acoustic stimulation and high frequency stimulation provided by the basal array section. As hearing loss progresses, the distal array section is selectively activated to treat lower frequency hearing loss using lower frequency stimulation.

    摘要翻译： 混合电极阵列包括基底阵列部分和远端阵列部分。 基础阵列部分被配置为提供高频刺激。 基底阵列部分被配置成延伸到耳蜗直到电刺激为高频丢失提供恢复的区域。 远端阵列部分被配置为附接到基部阵列部分的远侧末端，并且被配置为延伸到耳蜗到电刺激提供中低频听力损失恢复的区域。 对于进行性听力损失治疗，远端阵列部分在听力损失的初始阶段期间不被激活，允许患者依靠由基部阵列部分提供的声刺激和高频刺激的组合。 随着听力损失的进行，远端阵列部分被选择性地激活以使用较低频率的刺激来治疗较低频率的听力损失。

    Neural stimulator with percutaneous connectivity
    4.
    发明授权
    Neural stimulator with percutaneous connectivity 有权
    具有经皮连接的神经刺激器

    公开(公告)号：US08655455B2

    公开(公告)日：2014-02-18

    申请号：US13500731

    申请日：2010-09-30

    申请人： Alfred E. Mann ,  Tom Xiaohai He

    发明人： Alfred E. Mann ,  Tom Xiaohai He

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0539 ,  A61M39/0247 ,  A61M2039/0261 ,  A61M2039/0267 ,  A61N1/0536 ,  A61N1/36017 ,  A61N1/36128

    摘要： An implantable neurostimulation system includes both implantable and external components. Electrical connectivity between the external and implanted components is achieved through a plurality of feedthrough pins located within an insulative wall of a percutaneous port embedded in the skin. The percutaneous port has the general shape and appearance of a small thimble, embedded in the skin with its open end facing outwardly from the skin surface, and with its closed end located below the skin surface, thereby forming a cavity or dimple in the skin. Various plugs or cartridges can be removably inserted into the cavity of the percutaneous port, in various orientations, to facilitate appropriate connectivity between the external and implanted components of the system through selected ones of the feedthrough pins. A mesh edging secured around the periphery wall of the port promotes tissue ingrowth and vascularization, thereby forming a percutaneous seal around the port that prevents infection.

    摘要翻译： 植入式神经刺激系统包括可植入和外部组件。 外部和植入部件之间的电连接通过位于皮肤内的经皮端口的绝缘壁内的多个穿通针来实现。 经皮端口具有嵌入皮肤中的小套管的一般形状和外观，其开口端从皮肤表面向外，并且其封闭端位于皮肤表面下方，从而在皮肤中形成空腔或凹坑。 可以以各种取向将各种插头或药筒可移除地插入到经皮端口的空腔中，以通过选定的馈通针来促进系统的外部部件和植入部件之间的适当连接。 围绕端口的周围壁固定的网状边缘促进组织向内生长和血管形成，从而在端口周围形成防止感染的经皮密封。

    Methods and systems for placing an implanted stimulator for stimulating tissue
    8.
    发明授权
    Methods and systems for placing an implanted stimulator for stimulating tissue 失效
    放置刺激器刺激组织的方法和系统

    公开(公告)号：US07684858B2

    公开(公告)日：2010-03-23

    申请号：US11232540

    申请日：2005-09-21

    申请人： Tom Xiaohai He ,  Todd K. Whitehurst ,  Alfred E. Mann ,  Peter K. Johnson

    发明人： Tom Xiaohai He ,  Todd K. Whitehurst ,  Alfred E. Mann ,  Peter K. Johnson

    IPC分类号： A61N1/36

    CPC分类号： A61N1/372 ,  A61N1/37205

    摘要： Systems for providing stimulation with an implantable system control unit and for optimally positioning that system control unit include a system control unit configured to provide a stimulus to a patient with a member attached to the system control unit for pulling the system control unit into position within the patient. Methods of optimally positioning the implantable system control unit within a patient such that the system control unit is proximal to target tissue that is to be stimulated by the system control unit include threading a member through a patient's body using a needle, the member passing proximal to the target tissue and being attached to the system control unit, and pulling the system control unit into place with the member.

    摘要翻译： 用于用可植入系统控制单元提供刺激并且用于最佳地定位该系统控制单元的系统包括系统控制单元，该系统控制单元被配置为向患者提供具有连接到系统控制单元的构件的刺激，用于将系统控制单元牵引到 患者。 将可植入系统控制单元最佳地定位在患者体内的方法，使得系统控制单元靠近要由系统控制单元刺激的目标组织包括使用针穿过患者身体的部件，所述构件通过近端到 目标组织并附接到系统控制单元，并且将系统控制单元拉到构件的适当位置。