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公开(公告)号：US06767607B2
公开(公告)日：2004-07-27
申请号：US09925638
申请日：2001-08-09
IPC分类号： B32B310
CPC分类号： C09J5/00 , B32B3/10 , B32B17/10 , C09J2400/143 , C09J2425/006 , Y10T428/24273 , Y10T428/24331
摘要： A multiwell plate is described that is used for assaying samples and is made from a plastic upper plate which forms the sidewalls of one or more wells and a glass lower plate which forms the bottom walls of the wells. The plastic upper plate and glass lower plate are attached and bound to one another by an enhanced adhesive. The enhanced adhesive includes an adhesive mixed with an additive that interacts with the adhesive, the plastic upper plate and the glass bottom plate in a manner that strengthens a bond between the plastic upper plate and the glass lower plate. Also described herein is a method for making such multiwell plates.
摘要翻译： 描述了用于测定样品并由形成一个或多个孔的侧壁的塑料上板和形成孔的底壁的玻璃下板制成的多孔板。 塑料上板和玻璃下板通过增强的粘合剂彼此附接和粘合。 增强的粘合剂包括与加强剂混合的粘合剂，其以与加强剂粘合的方式与粘合剂，塑料上板和玻璃底板相互作用，以加强塑料上板和玻璃下板之间的粘结。 本文还描述了制造这种多孔板的方法。
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公开(公告)号：US07579179B2
公开(公告)日：2009-08-25
申请号：US10382681
申请日：2003-03-05
CPC分类号： B29C59/14 , B05D3/144 , B05D7/22 , B29C59/142
摘要： A product exhibiting an improved cell growth surface and cell attachment. According to the present invention, a stream of plasma is comprised of activated gaseous species generated by a microwave source. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion far superior to that of untreated polymer or polymer treated by other methods.
摘要翻译： 具有改善的细胞生长表面和细胞附着的产品。 根据本发明，等离子体流由微波源产生的活化气态物质组成。 该流以受控的方式指向聚合物基材的表面，使得该表面具有远远优于未处理的聚合物或通过其它方法处理的聚合物的细胞粘附的特性。
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公开(公告)号：US20090098645A1
公开(公告)日：2009-04-16
申请号：US11973832
申请日：2007-10-10
申请人： Ye Fang , Paul E. Gagnon, JR. , Terry T. Goodrich , Joydeep Lahiri , John S. Peanasky , Hongming Wang , Jun Xi
发明人： Ye Fang , Paul E. Gagnon, JR. , Terry T. Goodrich , Joydeep Lahiri , John S. Peanasky , Hongming Wang , Jun Xi
IPC分类号： C12M1/22
摘要： Disclosed is a cell culture article including: a substrate; a tie-layer attached to at least the substrate; and a bio-compatible layer attached to at least the tie layer, the bio-compatible layer having been obtained from surface oxidation of a polymer layer. Also disclosed are methods for making the cell culture article and methods for performing an assay of a ligand with the article.
摘要翻译： 公开了一种细胞培养物品，其特征在于，包括： 连接至少至少衬底的连接层; 以及连接到至少所述粘结层的生物相容层，所述生物相容层已经从聚合物层的表面氧化获得。 还公开了制备细胞培养物品的方法和用该物品进行配体测定的方法。
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4.发明申请METHOD FOR PRODUCING MULTIPHASE PARTICLE-REINFORCED METAL MATRIX COMPOSITES 审中-公开用于生产多相颗粒增强金属基复合材料的方法公开(公告)号：US20120060648A1
公开(公告)日：2012-03-15
申请号：US13319618
申请日：2009-05-25
申请人： Yutao Zhao , Hongming Wang , Gang Chen , Guirong Li
发明人： Yutao Zhao , Hongming Wang , Gang Chen , Guirong Li
IPC分类号： C22B4/00
CPC分类号： B22D11/115 , B22D1/00 , B22D41/015 , B22F2998/00 , C22C1/1036 , B22F2202/05
摘要： A method for producing multiphase particle-reinforced metal matrix composites is provided. The method is characterized by the combination of an in-situ reaction process under an external electromagnetic field and an in-situ crystallization process under an external electromagnetic field. A traveling wave magnetic field or a rotating magnetic field is employed during the in-situ reaction process, and a rotating magnetic field or a high frequency magnetic field is employed during the in-situ crystallization process. Said method can obtain homogeneous, gradient enhanced or surface reinforced composite materials.
摘要翻译： 提供了一种生产多相粒子增强金属基复合材料的方法。 该方法的特征在于外部电磁场下的原位反应过程和外部电磁场下的原位结晶过程的组合。 在原位反应过程中采用行波磁场或旋转磁场，在原位结晶过程中采用旋转磁场或高频磁场。 所述方法可以获得均匀的梯度增强或表面增强的复合材料。
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公开(公告)号：US07923241B2
公开(公告)日：2011-04-12
申请号：US11973832
申请日：2007-10-10
申请人： Ye Fang , Paul E. Gagnon, Jr. , Terry T. Goodrich , Joydeep Lahiri , John S. Peanasky , Hongming Wang , Jun Xi
发明人： Ye Fang , Paul E. Gagnon, Jr. , Terry T. Goodrich , Joydeep Lahiri , John S. Peanasky , Hongming Wang , Jun Xi
摘要： Disclosed is a cell culture article including: a substrate; a tie-layer attached to at least the substrate; and a bio-compatible layer attached to at least the tie layer, the bio-compatible layer having been obtained from surface oxidation of a polymer layer. Also disclosed are methods for making the cell culture article and methods for performing an assay of a ligand with the article.
摘要翻译： 公开了一种细胞培养物品，其特征在于，包括： 连接至少至少衬底的连接层; 以及连接到至少所述粘结层的生物相容层，所述生物相容层已经从聚合物层的表面氧化获得。 还公开了制备细胞培养物品的方法和用该物品进行配体测定的方法。
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公开(公告)号：US20080003663A1
公开(公告)日：2008-01-03
申请号：US11824289
申请日：2007-06-29
CPC分类号： B29C59/14 , B29C59/142 , C12N5/0068 , C12N2533/30
摘要： A method of producing an improved cell growth surface and cell attachment surface. According to the present invention, a polymer article is molded at temperature in excess of 550° F. at the injection tip. After allowing the part to cool, a stream of plasma comprised of activated gaseous species generated by a microwave source is imparted on the article. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion superior to those of untreated polymer or polymer treated by other methods.
摘要翻译： 一种生产改良的细胞生长表面和细胞附着表面的方法。 根据本发明，聚合物制品在注射尖端处的模制温度超过550°F。 在使部件冷却之后，将由微波源产生的活化气态物质组成的等离子体流送到制品上。 该流以受控的方式指向聚合物基材的表面，使得表面具有优于未经处理的聚合物或通过其它方法处理的聚合物的细胞粘附的特性。
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公开(公告)号：US06617152B2
公开(公告)日：2003-09-09
申请号：US09947035
申请日：2001-09-04
IPC分类号： C12M300
CPC分类号： B29C59/14 , B05D3/144 , B05D7/22 , B29C59/142
摘要： A method, apparatus and product for producing an advantaged cell growth surface. According to the present invention, a stream of plasma is comprised of activated gaseous species generated by a microwave source. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion far superior to that of untreated polymer or polymer treated by other known methods.
摘要翻译： 用于生产有利的细胞生长表面的方法，装置和产品。 根据本发明，等离子体流由微波源产生的活化气态物质组成。 该流以受控的方式指向聚合物基材的表面，使得该表面具有远优于未处理的聚合物或通过其它已知方法处理的聚合物的细胞粘附的特性。
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公开(公告)号：US08497126B2
公开(公告)日：2013-07-30
申请号：US11824289
申请日：2007-06-29
IPC分类号： C12N5/02
CPC分类号： B29C59/14 , B29C59/142 , C12N5/0068 , C12N2533/30
摘要： A method of producing an improved cell growth surface and cell attachment surface. According to the present invention, a polymer article is molded at temperature in excess of 550° F. at the injection tip. After allowing the part to cool, a stream of plasma comprised of activated gaseous species generated by a microwave source is imparted on the article. This stream is directed at the surface of a polymer substrate in a controlled fashion such that the surface is imparted with attributes for cell adhesion superior to those of untreated polymer or polymer treated by other methods.
摘要翻译： 一种生产改良的细胞生长表面和细胞附着表面的方法。 根据本发明，聚合物制品在注射尖端处的模制温度超过550°F。 在使部件冷却之后，将由微波源产生的活化气态物质组成的等离子体流送到制品上。 该流以受控的方式指向聚合物基材的表面，使得表面具有优于未经处理的聚合物或通过其它方法处理的聚合物的细胞粘附的特性。
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