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    LASER SPOT LIGHT WITH TWINKLING FUNCTION
    1.
    发明申请
    LASER SPOT LIGHT WITH TWINKLING FUNCTION 审中-公开

    公开(公告)号：US20180017234A1

    公开(公告)日：2018-01-18

    申请号：US15236439

    申请日：2016-08-14

    Applicant: Jun Xi

    Inventor： Jun Xi

    IPC: F21V14/08 ,  F21V11/14

    CPC classification number: F21V14/08 ,  F21V11/14 ,  F21V29/70 ,  F21V29/763 ,  F21W2121/00 ,  F21W2131/10 ,  F21Y2101/00 ,  F21Y2113/13

    Abstract: The present invention provides a laser spot light with twinkling function including a laser head, a body case defining an opening, a heat radiator supporting the laser head and fixed within the body case, a light baffle configured between the opening and the laser head, a first grating has a star pattern configured between the light baffle and the laser head, a second grating has a pattern of figures configured between the first grating and the laser head, a motor, a gearbox driven by the motor and configured to drive the light baffle to rotate or translate. The light baffle defines a plurality of through holes. The laser spot light of the invention utilize a motor driving a light baffle to rotate or translate, such that the static light spots generated by the first grating are blocked and unblocked alternately, resulting a lot of twinkling light spots.

    SURFACES AND METHODS FOR BIOSENSOR CELLULAR ASSAYS
    3.
    发明申请
    SURFACES AND METHODS FOR BIOSENSOR CELLULAR ASSAYS 审中-公开
    生物传感器细胞测定的表面和方法

    公开(公告)号：US20120061258A1

    公开(公告)日：2012-03-15

    申请号：US13298474

    申请日：2011-11-17

    Applicant: Ye Fang ,  Ann M. Ferrie ,  Elizabeth Tran ,  Jun Xi

    Inventor： Ye Fang ,  Ann M. Ferrie ,  Elizabeth Tran ,  Jun Xi

    IPC: G01N27/327 ,  G01N33/50 ,  B82Y5/00

    CPC classification number: G01N33/54373 ,  G01N33/569

    Abstract: Disclosed is an apparatus for measuring ligand-induced cell activity as defined herein, the apparatus including: an optical biosensor having a contact surface including a compatibilizer zone, an optional surface modifier zone, and a live cell zone. The disclosure also provides a method of making the apparatus and methods for measuring ligand-induced live cell activity with the apparatus.

    Abstract translation: 本发明公开了一种如本文所定义的用于测量配体诱导的细胞活性的装置，该装置包括：光学生物传感器，其具有包括增容剂区，任选的表面改性区和活细胞区的接触表面。 本公开还提供了一种制备用该装置测量配体诱导的活细胞活性的装置和方法的方法。

    PROJECTION LIGHT WITH COLOR FILM
    5.
    发明申请
    PROJECTION LIGHT WITH COLOR FILM 审中-公开

    公开(公告)号：US20180306411A1

    公开(公告)日：2018-10-25

    申请号：US15599676

    申请日：2017-05-19

    Applicant: Jun Xi

    Inventor： Jun Xi

    IPC: F21V14/00 ,  F21V21/30

    CPC classification number: F21V14/006 ,  F21V21/14 ,  F21V21/30 ,  F21W2131/10 ,  F21Y2115/10

    Abstract: The present invention provides a projection light with color film including a light source, a color film which can resist a temperature higher than 80 degrees Celsius without deformation and color fading, a film support configured for retaining the color film, a light guide column configured between the film support and the light source and configured for transmitting light from the light source to the color film, and a lens configured at a side of the color film and for receiving light passing through the color film. By using the PET material, the film base of the color film 40 has the ability to resist a high temperature up to 120 degrees Celsius. By using anti-uv screening inks, the printing layers do not easy to color fade. Therefore, the color film can operate properly without deformation and color fading during its lifetime.

    Laser spot light with twinkling function
    8.
    发明授权
    Laser spot light with twinkling function 有权

    公开(公告)号：US10041652B2

    公开(公告)日：2018-08-07

    申请号：US15236439

    申请日：2016-08-14

    Applicant: Jun Xi

    Inventor： Jun Xi

    IPC: F21V33/00 ,  F21V14/08 ,  F21V29/70 ,  F21V11/14 ,  F21Y113/13

    Abstract: The present invention provides a laser spot light with twinkling function including a laser head, a body case defining an opening, a heat radiator supporting the laser head and fixed within the body case, a light baffle configured between the opening and the laser head, a first grating has a star pattern configured between the light baffle and the laser head, a second grating has a pattern of figures configured between the first grating and the laser head, a motor, a gearbox driven by the motor and configured to drive the light baffle to rotate or translate. The light baffle defines a plurality of through holes. The laser spot light of the invention utilize a motor driving a light baffle to rotate or translate, such that the static light spots generated by the first grating are blocked and unblocked alternately, resulting a lot of twinkling light spots.

    Chemiluminescent energy transfer conjugates and their uses as labels in binding assays
    9.
    发明授权
    Chemiluminescent energy transfer conjugates and their uses as labels in binding assays 失效
    化学发光能量转移共轭物及其用作结合测定中的标记物

    公开(公告)号：US6165800A

    公开(公告)日：2000-12-26

    申请号：US86003

    申请日：1998-05-27

    Applicant: Qingping Jiang ,  Jun Xi ,  Anand Natrajan ,  David Sharpe ,  Marcus Baumann ,  Rolf Hilfiker ,  Erika Schmidt ,  Paul Senn ,  Fritz Thommen ,  Adrian Waldner ,  Alex Alder ,  Say-Jong Law

    Inventor： Qingping Jiang ,  Jun Xi ,  Anand Natrajan ,  David Sharpe ,  Marcus Baumann ,  Rolf Hilfiker ,  Erika Schmidt ,  Paul Senn ,  Fritz Thommen ,  Adrian Waldner ,  Alex Alder ,  Say-Jong Law

    IPC: C09B11/04 ,  C09B15/00 ,  C09K11/07 ,  G01N33/533 ,  G01N33/542 ,  G01N33/58 ,  C07D227/00 ,  G01N33/553

    CPC classification number: C09B15/00 ,  C09B11/04 ,  G01N33/533 ,  G01N33/542 ,  G01N33/582 ,  Y10S436/80 ,  Y10S436/816 ,  Y10S436/817

    Abstract: A new class of chemiluminescent acridinium or benzacridinium compounds is disclosed by virtue of forming an intramolecular energy transfer conjugate (ETC) between the acridinium or benzacridinium compound and a luminophore. A method of extending the emission wavelengths of acridinium or benzacridinium esters in order to further reduce or eliminate the emission spectral overlap between the parent polysubstituted aryl Acridinium Esters (DMAE) and Benzacridinium Esters (LEAE) is disclosed. The ETC's retain the unique desired properties of acridinium or benzacridinium compounds including complete light emission in very short period of time, monophasic emission spectrum, simplicity of triggering mechanism, ability of labeling the biological molecules of interest to form a tracer, and good stability. Additionally, the range of the emission spectrum of an acridinium or benzacridinium compound can now be shifted at will and at longer leap through the choice of a luminophore as the integral part of an ETC molecule. Disclosed are chemiluminescent labeled conjugates comprising an acridinium or benzacridinium moiety covalently attached to a luminophore via a spacer, said moiety further conjugated to a biological molecule of interest, wherein said spacer is of an appropriate length to allow the excited species generated from said moiety to transfer energy efficiently to said luminophore, resulting in the emission of light in the spectral region of said luminophore. Also disclosed are binding assays using said conjugates, test kits comprising said conjugates and methods of preparing the conjugates.

    Abstract translation: 通过在吖啶鎓或苯并吖啶鎓化合物和发光体之间形成分子内能量转移缀合物（ETC），公开了一类新的化学发光吖啶鎓或苯并吖啶鎓化合物。 公开了延长吖啶鎓或苯并吖啶酯的发射波长以进一步减少或消除母体多取代芳基吖啶酯（DMAE）和苯并吖啶酯（LEAE）之间的发射光谱重叠的方法。 ETC保留吖啶鎓或苯并吖啶鎓化合物独特的所需性质，包括在很短的时间内完全发光，单相发射光谱，触发机制简单，标记生物分子的能力，形成示踪剂，以及良好的稳定性。 此外，吖啶鎓或苯并吖啶鎓化合物的发射光谱的范围现在可以随意移动，并且通过选择发光体作为ETC分子的组成部分而更长的跨越。 公开了化学发光标记的缀合物，其包含通过间隔基共价连接到发光体的吖啶鎓或苯并吖啶鎓部分，所述部分还与感兴趣的生物分子缀合，其中所述间隔物具有适当长度以允许从所述部分产生的激发物质转移 能量有效地发送到所述发光体，导致发光在所述发光体的光谱区域。 还公开了使用所述缀合物的结合测定法，包含所述缀合物的测试试剂盒和制备缀合物的方法。

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