公开(公告)号：US20220022815A1

公开(公告)日：2022-01-27

申请号：US17311400

申请日：2019-12-05

申请人： LET'S - WEBEARABLE SOLUTIONS S.R.L. IN BREVE LET'S - S.R.L. ,  UNIVERSITÀ DEGLI STUDI DI CAGLIARI ,  ALMA MATER STUDIORUM - UNIVERSITÀ DI BOLOGNA

发明人： Marta TESSAROLO ,  Giuseppe Arnaldo USAI ,  Danilo PANI ,  Annalisa BONFIGLIO ,  Eleonora SULAS ,  Beatrice FRABONI

IPC分类号： A61B5/00 ,  A61B5/0205 ,  A41D1/00

摘要： A sensorized garment is provided. The sensorized garment includes an wearable element on a skin having a hand-tightening or a closure device to securely constrain sensors, for example electrodes to detect electrophysiological signals, during a physical activity. The wearable element has a three-dimensional shape to uniquely define a right side and a left part of a circumferential zone when the wearable element is worn. The sensorized garment further includes a band carried by the circumferential zone, and at least one conductor connected between the sensor and a zone of the sensorized garment.

公开(公告)号：US20240254436A1

公开(公告)日：2024-08-01

申请号：US18426809

申请日：2024-01-30

申请人： Alma Mater Studiorum - Università di Bologna

发明人： Stefania RAPINO ,  Francesco ZERBETTO ,  Gastone CASTELLANI ,  Stefano SALVIOLI ,  Beatrice FRABONI ,  Isabella ZIRONI ,  Maria CONTE ,  Claudio FRANCESCHI ,  Daniela SALVATORE ,  Maila BECCONI

IPC分类号： C12N5/00 ,  C12N5/09 ,  C12N9/00 ,  C12N9/02 ,  C12N9/04 ,  C12N9/08 ,  C12N11/04 ,  C12N11/06 ,  C12N11/087 ,  C12N11/089 ,  C12N11/12 ,  G01N33/50

CPC分类号： C12N5/0018 ,  C12N5/0068 ,  C12N5/0693 ,  C12N9/00 ,  C12N9/0006 ,  C12N9/0036 ,  C12N9/0053 ,  C12N9/0061 ,  C12N9/0065 ,  C12N9/0069 ,  C12N9/0093 ,  C12N11/04 ,  C12N11/06 ,  C12N11/087 ,  C12N11/089 ,  C12N11/12 ,  C12Y101/03004 ,  C12Y106/03001 ,  C12Y109/03001 ,  C12Y110/03002 ,  C12Y111/01006 ,  C12Y113/12004 ,  C12Y117/03002 ,  G01N33/5008 ,  C12N2500/02 ,  C12N2501/71 ,  C12N2533/30 ,  C12N2533/50 ,  C12N2533/54 ,  C12N2533/70 ,  C12N2533/72 ,  C12N2533/74 ,  C12N2533/76 ,  C12N2533/78 ,  C12N2533/80 ,  C12N2537/10

摘要： The present invention relates to compositions comprising a polymeric matrix or a gel containing functional enzymes capable of re-creating under culture conditions the cell microenvironment existing in vivo. The present invention also relates to devices for cell cultures comprising such compositions, in particular hydrogel and the use thereof to control the chemical microenvironment of a cell culture or mimic physiological or pathological conditions of the in vivo cells. The compositions and the devices described herein could be also used in vitro for evaluating the therapeutic effect of a compound on a determined cell line or on primary cells.

公开(公告)号：US20190300846A1

公开(公告)日：2019-10-03

申请号：US16339164

申请日：2017-10-03

申请人： Alma Mater Studiorum-Università di Bologna

发明人： Stefania RAPINO ,  Francesco ZERBETTO ,  Gastone CASTELLANI ,  Stefano SALVIOLI ,  Beatrice FRABONI ,  Isabella ZIRONI ,  Maria CONTE ,  Claudio FRANCESCHI ,  Daniela SALVATORE ,  Maila BECCONI

IPC分类号： C12N5/00 ,  C12N9/04 ,  C12N11/04 ,  C12N11/12 ,  C12N5/09 ,  C12N9/08 ,  C12N11/08 ,  G01N33/50

摘要： The present invention relates to compositions comprising a polymeric matrix or a gel containing functional enzymes capable of re-creating under culture conditions the cell microenvironment existing in vivo. The present invention also relates to devices for cell cultures comprising such compositions, in particular hydrogel and the use thereof to control the chemical microenvironment of a cell culture or mimic physiological or pathological conditions of the in vivo cells. The compositions and the devices described herein could be also used in vitro for evaluating the therapeutic effect of a compound on a determined cell line or on primary cells.

公开(公告)号：US20230277086A1

公开(公告)日：2023-09-07

申请号：US18040658

申请日：2021-08-04

申请人： ALMA MATER STUDIORUM - UNIVERSITÀ DI BOLOGNA

发明人： Roberta BONFIGLIOLI ,  Elena BORELLI ,  Beatrice FRABONI ,  Marta TESSAROLO ,  Lorenzo CHIARI ,  Francesco VIOLANTE

IPC分类号： A61B5/103 ,  A61B5/00

CPC分类号： A61B5/1036 ,  A61B5/6807 ,  A61B5/7275 ,  A61B2503/20

摘要： A system and method for assessing biomechanical risk in the context of handling heavy loads in workplaces. The system and method are applicable during a normal working activity for acquisitions lasting a work shift. The acquired data are then analysed in relation to regulatory references and international standards for the assessment of the biomechanical risk from manual handling of loads.