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公开(公告)号:US09089844B2
公开(公告)日:2015-07-28
申请号:US13287120
申请日:2011-11-01
申请人: Amy L. Hiddessen , Donald A. Masquelier , Kevin D. Ness , Benjamin J. Hindson , Anthony J. Makarewicz, Jr. , Erin R. Chia
发明人: Amy L. Hiddessen , Donald A. Masquelier , Kevin D. Ness , Benjamin J. Hindson , Anthony J. Makarewicz, Jr. , Erin R. Chia
CPC分类号: B01L3/502784 , B01F3/0807 , B01F13/0062 , B01F13/1022 , B01L3/502761 , B01L2200/0605 , B01L2200/0673 , B01L2300/0867 , B01L2400/0487 , G01N1/38 , G01N2035/1046 , Y10T137/0396 , Y10T137/8593
摘要: System, including methods, apparatus, and kits, for forming emulsions. The system may include an instrument and a microfluidic chip received by the instrument. The instrument may apply pressure to prospective emulsion phases held by the chip, to drive formation and collection of emulsions in the chip. In some embodiments, the instrument may stop applying pressure to the chip when a change in pressure meeting a predefined condition is detected by the instrument. The change may indicate that an endpoint of droplet generation has been reached.
摘要翻译: 用于形成乳液的系统,包括方法,装置和试剂盒。 该系统可以包括由仪器接收的仪器和微流体芯片。 仪器可以对由芯片保持的预期乳液相施加压力,以驱动芯片中的乳液的形成和收集。 在一些实施例中,当仪器检测到满足预定条件的压力变化时,仪器可能停止向芯片施加压力。 该变化可能表明已达到液滴产生的终点。
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公开(公告)号:US09393560B2
公开(公告)日:2016-07-19
申请号:US13341688
申请日:2011-12-30
IPC分类号: B01L3/02
CPC分类号: B01L3/021 , B01L2200/0673 , B01L2400/0478 , B01L2400/0622
摘要: Method of transporting droplets for detection. An emulsion disposed in a container and including droplets may be provided. Contact may be created between a tip and the emulsion. The tip may be connected to an examination region and may include an outer tube and an inner tube. The outer tube may form a first open end and surround an enclosed portion of the inner tube. The inner tube may extend out of the first open end to create a projecting portion forming a second open end below the first open end. Droplets of the emulsion may be loaded into the inner tube via the second open end. Loaded droplets may be moved from the inner tube to the examination region. Fluid may be dispensed onto the projecting portion of the inner tube from the first open end formed by the outer tube.
摘要翻译: 运输液滴检测方法。 可以提供设置在容器中并且包括液滴的乳液。 可以在尖端和乳液之间产生接触。 尖端可以连接到检查区域并且可以包括外管和内管。 外管可以形成第一开口端并且围绕内管的封闭部分。 内管可以延伸出第一开口端,以形成在第一开口端下方形成第二开口端的突出部分。 乳液的液滴可以经由第二开口端装载到内管中。 装载的液滴可以从内管移动到检查区域。 流体可以从由外管形成的第一开口端分配到内管的突出部分上。
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公开(公告)号:US09132394B2
公开(公告)日:2015-09-15
申请号:US13072673
申请日:2011-03-25
CPC分类号: B01F3/0807 , B01F13/0062 , B01L3/0241 , B01L3/502715 , B01L3/502784 , B01L3/563 , B01L7/52 , B01L7/525 , B01L2200/0689 , B01L2300/0816 , B01L2300/0819 , B01L2300/1822 , B01L2400/0478 , B01L2400/0487 , B01L2400/0622 , G01N21/645
摘要: System, including methods and apparatus, for detection of spaced droplets.
摘要翻译: 用于检测间隔液滴的系统,包括方法和装置。
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