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    Pressure sensing in implantable drug pumps
    5.
    发明授权
    Pressure sensing in implantable drug pumps 有权

    公开(公告)号：US10307530B2

    公开(公告)日：2019-06-04

    申请号：US14982246

    申请日：2015-12-29

    申请人： Jason Shih ,  Andrew Dunn

    发明人： Jason Shih ,  Andrew Dunn

    IPC分类号： A61M5/142 ,  A61M5/145 ,  G01L1/22

    摘要： In various embodiments, approaches to calibrating an implantable drug-delivery device feature a drug reservoir, an expandable electrolysis chamber, and an integrated strain gauge using a refill apparatus having one or more pumps, one or more refill reservoirs, an outlet fluid channel fluidically connected to the refill reservoir(s), and a needle having a lumen in fluid communication with the outlet fluid channel include inserting a needle into a refill port of the implantable drug-delivery device, monitoring a pressure change within the device, monitoring a pressure level of one or more components of the implantable drug-delivery device, and calibrating the monitored pressure level of the component(s) of the implantable drug-delivery device to the monitored pressure level of the outlet fluid channel.

    DRUG REFILL APPLICATOR SYSTEM AND METHOD OF USE
    10.
    发明申请
    DRUG REFILL APPLICATOR SYSTEM AND METHOD OF USE 审中-公开
    药物补充施用者系统及其使用方法

    公开(公告)号：US20150174007A1

    公开(公告)日：2015-06-25

    申请号：US14579231

    申请日：2014-12-22

    申请人： Andres Rodriguez ,  Pedrum Minaie ,  Tun Min Soe ,  Jason Shih ,  Andrew Dunn ,  Andrew Urazaki ,  Bin Wang ,  Fukang Jiang

    发明人： Andres Rodriguez ,  Pedrum Minaie ,  Tun Min Soe ,  Jason Shih ,  Andrew Dunn ,  Andrew Urazaki ,  Bin Wang ,  Fukang Jiang

    IPC分类号： A61J1/22 ,  A61M5/142 ,  B65B3/00

    CPC分类号： A61J1/22 ,  A61J1/201 ,  A61M5/14276 ,  A61M2005/14268 ,  B65B3/003

    摘要： Embodiments of the present invention involve a refill apparatus comprising at least one pump, a plurality of reservoirs, a plurality of reservoir fluid channels each associated with one of the reservoirs, a plurality of valves, each having a cracking pressure, for fluidically sealing the reservoir fluid channels and the outlet fluid channel, an outlet fluid channel fluidically connected to the reservoir fluid channels, and a needle having a lumen in fluid communication with the outlet fluid channel. A parameter such as a pressure level is monitored, and one or more pumps and various ones of the valves are actuated in accordance with a protocol comprising a sequence of steps whereby fluidic pathways are opened between different ones of the reservoirs and the needle in a washing and filling sequence, each of the steps being associated with an expected pressure level.

    摘要翻译： 本发明的实施例涉及一种再填充装置，其包括至少一个泵，多个储存器，多个储存器流体通道，每个储存器流体通道与储存器中的一个相关联，多个阀，每个具有开启压力，用于流体地密封储存器 流体通道和出口流体通道，流体连接到储存器流体通道的出口流体通道，以及具有与出口流体通道流体连通的内腔的针。 监测诸如压力水平的参数，并且根据包括一系列步骤的方案致动一个或多个泵和各种阀，其中在洗涤中不同储存器和针之间的流体路径打开 和填充顺序，每个步骤与预期压力水平相关联。