摘要:
A building includes a connection between an engineered wood load bearing element of the building such as a column, beam, or load bearing panel, and another load bearing element or a foundation of the building. At least one tendon ties the load bearing elements or the load bearing element and the foundation together. One or more energy dissipaters, replaceably connected between the load bearing element and/or the foundation, absorb energy when a loading event causes relative movement of the connection. The engineered wood element may be a laminated veneer lumber element, a parallel strand lumber element, or a glue laminated timber element, for example. Typically all of the load bearing elements of the building will be engineered wood elements. The building may be single or multi-storey. The building system enables lightweight low cost buildings, with energy dissipaters which may be replaced after extreme loading. The building may be prefabricated.
摘要:
A building includes a connection between an engineered wood load bearing element of the building such as a column, beam, or load bearing panel, and another load bearing element or a foundation of the building. At least one tendon ties the load bearing elements or the load bearing element and the foundation together. One or more energy dissipaters, replaceably connected between the load bearing element and/or the foundation, absorb energy when a loading event causes relative movement of the connection. The engineered wood element may be a laminated veneer lumber element, a parallel strand lumber element, or a glue laminated timber element, for example. Typically all of the load bearing elements of the building will be engineered wood elements. The building may be single or multi-storey. The building system enables lightweight low cost buildings, with energy dissipaters which may be replaced after extreme loading. The building may be prefabricated.
摘要:
A building includes a connection between an engineered wood load bearing element of the building such as a column, beam, or load bearing panel, and another load bearing element or a foundation of the building. At least one tendon ties the load bearing elements or the load bearing element and the foundation together. One or more energy dissipaters, replacably connected between the load bearing element and/or the foundation, absorb energy when a loading event causes relative movement of the connection. The engineered wood element maybe a laminated veneer lumber element, a parallel strand lumber element, or a glue laminated timber element, for example. Typically all of the load bearing elements of the building will be engineered wood elements. The building may be single or multi-storey. The building system enables lightweight low cost buildings, with energy dissipaters which may be replaced after extreme loading. The building may be prefabricated
摘要:
Stabilized antibodies directed to Angiopoeitin-2 and uses of such antibodies are described. Nucleic acid and amino acid sequences, hybridomas or other cell lines for expressing such antibodies are also provided.
摘要:
Specific binding members for Nerve Growth Factor (NGF), in particular anti-NGF antibody molecules, especially human antibody molecules, and especially those that neutralise NGF activity. Methods for using anti-NGF antibody molecules in diagnosis or treatment of NGF related disorders, including pain, asthma, chronic obstructive pulmonary disease, pulmonary fibrosis, other diseases of airway inflammation, diabetic neuropathy, cardiac arrhythmias, HIV, arthritis, psoriasis and cancer.
摘要:
Stabilized antibodies directed to Angiopoeitin-2 and uses of such antibodies are described. Nucleic acid and amino acid sequences, hybridomas or other cell lines for expressing such antibodies are also provided.
摘要:
A method of providing a subject polypeptide variant with improved stability compared with a parent subject polypeptide, employing translation and selection using an RNA expression system, wherein two or more stability selection pressures are applied simultaneously during translation, two or more stability selection pressures are applied simultaneously during selecting, or at least one stability selection pressure is applied during translation and continues to be applied during selecting, and at least one further stability selection pressure is applied during selecting.
摘要:
A method of providing a subject polypeptide variant with improved stability compared with a parent subject polypeptide, employing translation and selection using an RNA expression system, wherein two or more stability selection pressures are applied simultaneously during translation, two or more stability selection pressures are applied simultaneously during selecting, or at least one stability selection pressure is applied during translation and continues to be applied during selecting, and at least one further stability selection pressure is applied during selecting.
摘要:
A method of providing a subject polypeptide variant with improved stability compared with a parent subject polypeptide, employing translation and selection using an RNA expression system, wherein two or more stability selection pressures are applied simultaneously during translation, two or more stability selection pressures are applied simultaneously during selecting, or at least one stability selection pressure is applied during translation and continues to be applied during selecting, and at least one further stability selection pressure is applied during selecting.