Engineered microorganisms for increasing product yield in biotransformations, related methods and systems
    2.
    发明申请
    Engineered microorganisms for increasing product yield in biotransformations, related methods and systems 审中-公开
    用于提高生物转化,相关方法和系统中产品产量的工程微生物

    公开(公告)号:US20080293101A1

    公开(公告)日:2008-11-27

    申请号:US11881748

    申请日:2007-07-27

    CPC分类号: C12N9/0036

    摘要: There are disclosed recombinant microorganisms engineered to increase product yield in a biotransformation. In an embodiment, the microorganisms are engineered to increase the amount of NAD(P)H available for a NAD(P)H-requiring oxidoreductase involved in a biotransformation. There are also disclosed methods and systems for using recombinant microorganisms engineered to increase the amount of NAD(P)H available for a NAD(P)H-requiring oxidoreductase involved in a biotransformation. Other embodiments are also disclosed.

    摘要翻译: 公开了在生物转化中改进产物产率的重组微生物。 在一个实施方案中,将微生物工程化以增加可用于参与生物转化的NAD(P)H需氧化还原酶的NAD(P)H的量。 还公开了使用重组微生物进行工程改造以增加参与生物转化的NAD(P)H需氧化还原酶可用的NAD(P)H量的方法和系统。 还公开了其他实施例。