公开(公告)号：US06511468B1

公开(公告)日：2003-01-28

申请号：US09387274

申请日：1999-08-31

申请人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George Robert Greene ,  George Wallace ,  Richard J. Greff

发明人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George Robert Greene ,  George Wallace ,  Richard J. Greff

IPC分类号： A61M3100

CPC分类号： A61B17/12195 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12136 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00495 ,  A61B2017/00876 ,  A61B2017/00893 ,  A61B2017/1205 ,  A61B2017/12059 ,  A61B2017/12063 ,  A61M25/00 ,  A61M25/0028 ,  A61M25/0097 ,  A61M2025/0036 ,  A61M2025/004

摘要： A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.

摘要翻译： 提供液体栓塞递送系统用于捕获注射的液体栓塞组合物以防止液体栓塞凝固或以其他方式通过栓塞区域外部。 递送系统包括用于输送液体栓塞组合物的导管和定位在导管远端的容纳构件，其被成形为捕获通过导管内腔输送的液体栓塞组合物。 容纳构件形成为注射液体栓塞组合物的周围的刷子，巢，海绵，拭子，柔性袋或其它形状。 在包含液体栓塞的凝固期间，液体栓塞组合物被捕获或与容纳构件啮合，并防止栓塞组合物进入血流。

公开(公告)号：US20110264073A1

公开(公告)日：2011-10-27

申请号：US13152208

申请日：2011-06-02

申请人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George Robert Greene ,  George Wallace ,  Richard J. Greff

发明人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George Robert Greene ,  George Wallace ,  Richard J. Greff

IPC分类号： A61M31/00 ,  A61M29/00

CPC分类号： A61B17/12195 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12136 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00495 ,  A61B2017/00876 ,  A61B2017/00893 ,  A61B2017/1205 ,  A61B2017/12059 ,  A61B2017/12063 ,  A61M25/00 ,  A61M25/0028 ,  A61M25/0097 ,  A61M2025/0036 ,  A61M2025/004

摘要： A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.

摘要翻译： 提供液体栓塞递送系统用于捕获注射的液体栓塞组合物以防止液体栓塞凝固或以其他方式通过栓塞区域外部。 递送系统包括用于输送液体栓塞组合物的导管和定位在导管远端的容纳构件，其被成形为捕获通过导管内腔输送的液体栓塞组合物。 容纳构件形成为注射液体栓塞组合物的周围的刷子，巢，海绵，拭子，柔性袋或其它形状。 在包含液体栓塞的凝固期间，液体栓塞组合物被捕获或与容纳构件啮合，并防止栓塞组合物进入血流。

公开(公告)号：US08454649B2

公开(公告)日：2013-06-04

申请号：US13152208

申请日：2011-06-02

申请人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George Robert Greene ,  George Wallace ,  Richard J. Greff

发明人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George Robert Greene ,  George Wallace ,  Richard J. Greff

IPC分类号： A61M29/00

CPC分类号： A61B17/12195 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12136 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00495 ,  A61B2017/00876 ,  A61B2017/00893 ,  A61B2017/1205 ,  A61B2017/12059 ,  A61B2017/12063 ,  A61M25/00 ,  A61M25/0028 ,  A61M25/0097 ,  A61M2025/0036 ,  A61M2025/004

摘要： A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.

公开(公告)号：US07976527B2

公开(公告)日：2011-07-12

申请号：US11923495

申请日：2007-10-24

申请人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George R. Greene ,  George Wallace ,  Richard J. Greff

发明人： Andrew H. Cragg ,  Blair D. Walker ,  John Perl, II ,  Michael Jones ,  George R. Greene ,  George Wallace ,  Richard J. Greff

IPC分类号： A61M31/00

CPC分类号： A61B17/12195 ,  A61B17/00491 ,  A61B17/12022 ,  A61B17/12113 ,  A61B17/12136 ,  A61B17/12168 ,  A61B17/12172 ,  A61B17/12177 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00495 ,  A61B2017/00876 ,  A61B2017/00893 ,  A61B2017/1205 ,  A61B2017/12059 ,  A61B2017/12063 ,  A61M25/00 ,  A61M25/0028 ,  A61M25/0097 ,  A61M2025/0036 ,  A61M2025/004

摘要： A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.

摘要翻译： 提供液体栓塞递送系统用于捕获注射的液体栓塞组合物以防止液体栓塞凝固或以其他方式通过栓塞区域外部。 递送系统包括用于输送液体栓塞组合物的导管和定位在导管远端的容纳构件，其被成形为捕获通过导管内腔输送的液体栓塞组合物。 容纳构件形成为注射液体栓塞组合物的周围的刷子，巢，海绵，拭子，柔性袋或其它形状。 在包含液体栓塞的凝固期间，液体栓塞组合物被捕获或与容纳构件啮合，并防止栓塞组合物进入血流。

公开(公告)号：US20110172768A1

公开(公告)日：2011-07-14

申请号：US12949204

申请日：2010-11-18

申请人： Andrew H. Cragg ,  Richard J. Greff ,  George Wallace ,  Robert J. Socci, JR. ,  Jonathan Kagan ,  Rodolfo C. Quijano ,  Hosheng Tu

发明人： Andrew H. Cragg ,  Richard J. Greff ,  George Wallace ,  Robert J. Socci, JR. ,  Jonathan Kagan ,  Rodolfo C. Quijano ,  Hosheng Tu

IPC分类号： A61F2/08

CPC分类号： A61F2/30756 ,  A61F2/3872 ,  A61F2/461 ,  A61F2002/4635 ,  A61L27/20 ,  A61L27/50 ,  A61L27/52 ,  C08L5/08

摘要： A medical device and methods to relieve joint pain and adapted for knee joint repair, replacement and augmentation. The invention discloses joint lubricant, particularly hyaluronate compositions and methods for treatment of osteoarthritis.

摘要翻译： 一种减轻关节疼痛并适应膝关节修复，置换和增大的医疗装置和方法。 本发明公开了关节润滑剂，特别是透明质酸盐组合物和治疗骨关节炎的方法。

公开(公告)号：US06558367B1

公开(公告)日：2003-05-06

申请号：US09573154

申请日：2000-05-19

申请人： Andrew H. Cragg ,  Richard J. Greff ,  Robert Pecor ,  John Perl ,  Blair Walker ,  George Wallace

发明人： Andrew H. Cragg ,  Richard J. Greff ,  Robert Pecor ,  John Perl ,  Blair Walker ,  George Wallace

IPC分类号： A61M2500

CPC分类号： A61B17/12022 ,  A61B17/00491 ,  A61B17/12113 ,  A61B17/12186 ,  A61B90/39 ,  A61B2017/00495 ,  A61B2017/1205 ,  A61M25/00 ,  A61M25/0097 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2025/0039

摘要： A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent. The controlled solidification of the liquid embolic composition by use of the solidification agent allows the aneurysm to be filled precisely and rapidly even when the aneurysm is located such that gravity does not cause the liquid embolic composition to flow into the aneurysm.

公开(公告)号：US6146373A

公开(公告)日：2000-11-14

申请号：US953149

申请日：1997-10-17

申请人： Andrew H. Cragg ,  Richard J. Greff ,  Robert Pecor ,  John Perl ,  Blair Walker ,  George Wallace

发明人： Andrew H. Cragg ,  Richard J. Greff ,  Robert Pecor ,  John Perl ,  Blair Walker ,  George Wallace

IPC分类号： A61B17/00 ,  A61B17/12 ,  A61M25/00 ,  A61M37/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12186 ,  A61B17/00491 ,  A61B2017/00495 ,  A61B2017/1205 ,  A61B90/39 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2025/0039 ,  A61M25/00 ,  A61M25/0097

摘要： A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent. The controlled solidification of the liquid embolic composition by use of the solidification agent allows the aneurysm to be filled precisely and rapidly even when the aneurysm is located such that gravity does not cause the liquid embolic composition to flow into the aneurysm.

公开(公告)号：US08287594B2

公开(公告)日：2012-10-16

申请号：US12949204

申请日：2010-11-18

申请人： Andrew H. Cragg ,  Richard J. Greff ,  George Wallace ,  Robert J. Socci, Jr. ,  Jonathan Kagan ,  Rodolfo C. Quijano ,  Hosheng Tu

发明人： Andrew H. Cragg ,  Richard J. Greff ,  George Wallace ,  Robert J. Socci, Jr. ,  Jonathan Kagan ,  Rodolfo C. Quijano ,  Hosheng Tu

IPC分类号： A61F2/08

CPC分类号： A61F2/30756 ,  A61F2/3872 ,  A61F2/461 ,  A61F2002/4635 ,  A61L27/20 ,  A61L27/50 ,  A61L27/52 ,  C08L5/08

摘要： A medical device and methods to relieve joint pain and adapted for knee joint repair, replacement and augmentation. The invention discloses joint lubricant, particularly hyaluronate compositions and methods for treatment of osteoarthritis.

摘要翻译： 一种减轻关节疼痛并适应膝关节修复，置换和增大的医疗装置和方法。 本发明公开了关节润滑剂，特别是透明质酸盐组合物和治疗骨关节炎的方法。

公开(公告)号：US06964657B2

公开(公告)日：2005-11-15

申请号：US10361851

申请日：2003-02-11

申请人： Andrew H. Cragg ,  Richard J. Greff ,  Robert Pecor ,  John Perl ,  Blair Walker ,  George Wallace

发明人： Andrew H. Cragg ,  Richard J. Greff ,  Robert Pecor ,  John Perl ,  Blair Walker ,  George Wallace

IPC分类号： A61B17/00 ,  A61B17/12 ,  A61M25/00 ,  A61M37/00 ,  A61M31/00

CPC分类号： A61B17/12022 ,  A61B17/00491 ,  A61B17/12113 ,  A61B17/12186 ,  A61B90/39 ,  A61B2017/00495 ,  A61B2017/1205 ,  A61M25/00 ,  A61M25/0097 ,  A61M2025/0034 ,  A61M2025/0037 ,  A61M2025/0039

摘要： A catheter according to the present invention includes a multiple lumen catheter for delivery of a liquid embolic composition through a first lumen and delivery of a solidification agent through a second lumen. The catheter allows adjustment of the relative longitudinal position of the two lumens to control the solidification of the embolic composition within a blood vessel. The multiple lumen catheter system is used by inserting the catheter endovascularly into an aneurysm site and injecting a liquid embolic composition through the first lumen while injecting a solidification agent through the second lumen to wash the area of the aneurysm of blood which has become saturated with solvent, while replacing it with a fresh solidification agent. The controlled solidification of the liquid embolic composition by use of the solidification agent allows the aneurysm to be filled precisely and rapidly even when the aneurysm is located such that gravity does not cause the liquid embolic composition to flow into the aneurysm.

摘要翻译： 根据本发明的导管包括多腔导管，用于通过第一腔输送液体栓塞组合物并且通过第二腔输送凝固剂。 导管允许调整两个腔的相对纵向位置以控制栓塞组合物在血管内的凝固。 通过将血管内导管插入动脉瘤部位并通过第一管腔注射液体栓塞组合物，同时通过第二腔注入凝固剂来洗涤已经变得饱和的血液的动脉瘤的区域，使用多腔导管系统 ，同时用新鲜的固化剂代替。 通过使用凝固剂对液体栓塞组合物的受控凝固允许即使当动脉瘤被定位成使得重力不会使液体栓塞组合物流入动脉瘤时，动脉瘤被精确和快速地填充。

公开(公告)号：US20100305686A1

公开(公告)日：2010-12-02

申请号：US12628131

申请日：2009-11-30

申请人： Andrew H. Cragg ,  Rodolfo C. Quijano ,  Hosheng Tu ,  Stephen Sosnowski ,  Robert J. Socci, JR. ,  George Wallace

发明人： Andrew H. Cragg ,  Rodolfo C. Quijano ,  Hosheng Tu ,  Stephen Sosnowski ,  Robert J. Socci, JR. ,  George Wallace

IPC分类号： A61F2/82

CPC分类号： A61F2/954 ,  A61F2/07 ,  A61F2/89 ,  A61F2002/067 ,  A61F2002/8483 ,  A61F2002/9534 ,  A61F2230/0034 ,  A61F2250/0098

摘要： Systems methods and devices address and ameliorate intralumenal aneurysms by excluding the same through endograft by pass techniques. Percutaneuous emplacement, use of improved aortic-stent assemblies and shotgun neck framing facilitates placement of modular graft sections, for example, to treat abdominal aortic aneurysms.

摘要翻译： 系统方法和装置通过通过技术通过内移植物排除同样的手术来解决和改善腔内动脉瘤。 使用改良的主动脉 - 支架组件和霰弹枪颈部框架可有助于放置模块化移植部分，例如治疗腹主动脉瘤。