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12 条记录 (耗时 0.043 秒)

    PEG-conjugated erythropoietin
    3.
    发明申请
    PEG-conjugated erythropoietin 有权
    PEG结合的促红细胞生成素

    公开(公告)号：US20060276634A1

    公开(公告)日：2006-12-07

    申请号：US11498053

    申请日：2006-08-03

    申请人： Teruo Nakamura ,  Yasuo Sekimori ,  Minoru Machida ,  Hiromitsu Kawata ,  Hajime Miyamoto

    发明人： Teruo Nakamura ,  Yasuo Sekimori ,  Minoru Machida ,  Hiromitsu Kawata ,  Hajime Miyamoto

    IPC分类号： A61K38/18 ,  C07K14/51

    CPC分类号： C07K14/505 ,  A61K38/1816 ,  A61K47/60

    摘要： The present invention provides a polyethylene glycol-conjugated erythropoietin (PEG-conjugated EPO) prepared by PEG conjugation on the lysine residue at position 52 of native erythropoietin (native EPO). In order to achieve more sustained efficacy without losing physiological activities of native EPO, a glycoprotein rich in sugar chains, there has been a need to develop a PEG-conjugated EPO with significantly sustained efficacy by introducing a controlled number of PEG molecules at controlled positions. This PEG-conjugated EPO addresses such a need and provides more sustained efficacy.

    摘要翻译： 本发明提供通过PEG缀合在天然促红细胞生成素（天然EPO）的52位的赖氨酸残基上制备的聚乙二醇缀合的促红细胞生成素（PEG-缀合的EPO）。 为了获得更持久的功效而不损失富含糖链的糖蛋白的天然EPO的生理活性，需要通过在受控位置引入受控数量的PEG分子来开发具有显着持续功效的PEG-缀合的EPO。 这种PEG结合的EPO解决了这种需要并提供更持久的功效。

    self-diagnosing system for encoder
    4.
    发明申请
    self-diagnosing system for encoder 有权
    编码器自诊断系统

    公开(公告)号：US20050171713A1

    公开(公告)日：2005-08-04

    申请号：US11049079

    申请日：2005-02-03

    申请人： Mitsuyuki Taniguchi ,  Hirofumi Kikuchi ,  Hajime Miyamoto

    发明人： Mitsuyuki Taniguchi ,  Hirofumi Kikuchi ,  Hajime Miyamoto

    IPC分类号： G01D5/245 ,  G01D5/244 ,  G06F19/00

    CPC分类号： G01D5/24457 ,  G01D5/24461

    摘要： A self-diagnosing system for an encoder. The system includes an encoder circuit for outputting information detected by an encoder; a data preparing section provided in the encoder circuit and preparing data representing a state of an abnormal-state judgment factor in connection with at least one of the encoder and an electric motor combined with the encoder; a signal generating section provided in the encoder circuit and generating an abnormal-state signal when the data prepared in the data preparing section represents an abnormal state of the abnormal-state judgment factor; and a storage section provided in the encoder circuit and storing the data representing a state of the abnormal-state judgment factor when the signal generating section generates the abnormal-state signal. The storage section may store the data prepared in the data preparing section at a desired timing not later than the instant the signal generating section generates the abnormal-state signal.

    摘要翻译： 用于编码器的自诊断系统。 该系统包括用于输出由编码器检测到的信息的编码器电路; 数据准备部分，设置在编码器电路中，并且与编码器和电动机组合的编码器和电动机中的至少一个相关地准备表示异常状态判断系数的状态的数据; 当在数据准备部分中准备的数据表示异常状态判断因子的异常状态时，设置在编码器电路中并产生异常状态信号的信号产生部分; 以及设置在编码器电路中的存储部分，并且当信号产生部分产生异常状态信号时，存储表示异常状态判断因子的状态的数据。 存储部可以在不迟于信号生成部生成异常状态信号的时刻的期望的时刻存储准备在数据准备部中的数据。

    Nonaqueous secondary battery and process for preparation thereof
    5.
    发明授权
    Nonaqueous secondary battery and process for preparation thereof 失效
    非水二次电池及其制备方法

    公开(公告)号：US6053953A

    公开(公告)日：2000-04-25

    申请号：US18336

    申请日：1998-02-04

    申请人： Hideki Tomiyama ,  Hiroshi Fujimoto ,  Hajime Miyamoto

    发明人： Hideki Tomiyama ,  Hiroshi Fujimoto ,  Hajime Miyamoto

    IPC分类号： H01M6/10 ,  H01M10/052 ,  H01M10/0525 ,  H01M10/44 ,  H01M6/00

    CPC分类号： H01M10/0525 ,  H01M10/44 ,  H01M4/382 ,  H01M10/052 ,  H01M10/446 ,  H01M6/10 ,  Y10T29/49108

    摘要： A nonaqueous secondary battery is disclosed, comprising a positive electrode sheet containing a lithium-containing transition metal oxide as a positive electrode active material, a negative electrode sheet having at least one layer containing a negative electrode material capable of intercalating and deintercalating lithium, and a nonaqueous electrolyte containing a lithium metal salt, wherein the battery into which an electrolytic solution has been injected is sealed, subjected to charging treatment having at least two stages, and subjected to storage treatment having at least two steps. A process for preparing such the nonaqueous secondary battery is also disclosed.

    摘要翻译： 公开了一种非水系二次电池，其包含含有含锂过渡金属氧化物作为正极活性物质的正极片，具有至少一层含有能够嵌入和脱嵌锂的负极材料的负极片，以及 含有锂金属盐的非水电解质，其中已经注入了电解液的电池被密封，进行至少两个阶段的充电处理，并进行至少两个步骤的储存处理。 还公开了制备这种非水二次电池的方法。

    PEG-conjugated erythropoietin
    8.
    发明授权
    PEG-conjugated erythropoietin 有权
    PEG结合的促红细胞生成素

    公开(公告)号：US08022191B2

    公开(公告)日：2011-09-20

    申请号：US11498053

    申请日：2006-08-03

    申请人： Teruo Nakamura ,  Yasuo Sekimori ,  Minoru Machida ,  Hiromitsu Kawata ,  Hajime Miyamoto

    发明人： Teruo Nakamura ,  Yasuo Sekimori ,  Minoru Machida ,  Hiromitsu Kawata ,  Hajime Miyamoto

    IPC分类号： A61K38/18

    CPC分类号： C07K14/505 ,  A61K38/1816 ,  A61K47/60

    摘要： The present invention provides a polyethylene glycol-conjugated erythropoietin (PEG-conjugated EPO) prepared by PEG conjugation on the lysine residue at position 52 of native erythropoietin (native EPO). In order to achieve more sustained efficacy without losing physiological activities of native EPO, a glycoprotein rich in sugar chains, there has been a need to develop a PEG-conjugated EPO with significantly sustained efficacy by introducing a controlled number of PEG molecules at controlled positions. This PEG-conjugated EPO addresses such a need and provides more sustained efficacy.

    摘要翻译： 本发明提供通过PEG缀合在天然促红细胞生成素（天然EPO）的52位的赖氨酸残基上制备的聚乙二醇缀合的促红细胞生成素（PEG-缀合的EPO）。 为了获得更持久的功效而不损失富含糖链的糖蛋白的天然EPO的生理活性，需要通过在受控位置引入受控数量的PEG分子来开发具有显着持续功效的PEG-缀合的EPO。 这种PEG结合的EPO解决了这种需要并提供更持久的功效。

    Self-diagnosing system for encoder
    9.
    发明授权
    Self-diagnosing system for encoder 有权
    编码器自诊断系统

    公开(公告)号：US07209862B2

    公开(公告)日：2007-04-24

    申请号：US11049079

    申请日：2005-02-03

    申请人： Mitsuyuki Taniguchi ,  Hirofumi Kikouchi ,  Hajime Miyamoto

    发明人： Mitsuyuki Taniguchi ,  Hirofumi Kikouchi ,  Hajime Miyamoto

    IPC分类号： G05B11/26

    CPC分类号： G01D5/24457 ,  G01D5/24461

    摘要： A self-diagnosing system for an encoder. The system includes an encoder circuit for outputting information detected by an encoder; a data preparing section provided in the encoder circuit and preparing data representing a state of an abnormal-state judgment factor in connection with at least one of the encoder and an electric motor combined with the encoder; a signal generating section provided in the encoder circuit and generating an abnormal-state signal when the data prepared in the data preparing section represents an abnormal state of the abnormal-state judgment factor; and a storage section provided in the encoder circuit and storing the data representing a state of the abnormal-state judgment factor when the signal generating section generates the abnormal-state signal. The storage section may store the data prepared in the data preparing section at a desired timing not later than the instant the signal generating section generates the abnormal-state signal.

    摘要翻译： 用于编码器的自诊断系统。 该系统包括用于输出由编码器检测到的信息的编码器电路; 数据准备部分，设置在编码器电路中，并且与编码器和电动机组合的编码器和电动机中的至少一个相关地准备表示异常状态判断系数的状态的数据; 当在数据准备部分中准备的数据表示异常状态判断因子的异常状态时，设置在编码器电路中并产生异常状态信号的信号产生部分; 以及设置在编码器电路中的存储部分，并且当信号产生部分产生异常状态信号时，存储表示异常状态判断因子的状态的数据。 存储部可以在不迟于信号生成部生成异常状态信号的时刻的期望的时刻存储准备在数据准备部中的数据。