公开(公告)号：US06432050B1

公开(公告)日：2002-08-13

申请号：US09303644

申请日：1999-05-03

申请人： Yariv Porat ,  Avi Penner ,  Eyal Doron

发明人： Yariv Porat ,  Avi Penner ,  Eyal Doron

IPC分类号： A61B500

CPC分类号： A61B5/02158 ,  A61B5/0031 ,  A61B5/026 ,  A61B5/031 ,  A61B5/413 ,  A61B2562/028 ,  A61M2205/3523 ,  G01F1/36 ,  G01F1/72 ,  H01L41/1138 ,  H04R17/00

摘要： An implantable biosensor system for monitoring and optionally alleviating a physiological condition in a patient is provided and includes (a) at least one sensor for sensing at least one parameter of a physiological condition and for generating electrical sensor signals representative of the physiological condition; and (b) a first acoustic activatable transducer being directly or indirectly coupled with the at least one sensor, the first acoustic activatable transducer being for converting a received acoustic interrogation signal from outside the patient's body into an electrical power for energizing the processor, the first acoustic activatable transducer further being for converting the electrical sensor signals of the at least one sensor into acoustic signals receivable out of the patient's body, such that information pertaining to the at least one parameter of the physiological condition can be relayed outside the patient's body upon generation of an acoustic interrogation signal.

摘要翻译： 提供了一种用于监测和任选地减轻患者生理状况的植入式生物传感器系统，其包括（a）至少一个用于感测至少一个生理状态参数并用于产生代表生理状态的电传感器信号的传感器; 所述第一声学可激活换能器用于将接收到的来自患者身体外部的声学询问信号转换成用于激励所述处理器的电力，所述第一声学可激活换能器与所述至少一个传感器直接或间接耦合， 声学可激活的换能器还用于将至少一个传感器的电传感器信号转换成可从患者身体接收的声信号，使得与生理状况的至少一个参数相关的信息可以在生成后被中继到患者体外 的声讯讯号。

公开(公告)号：US06239724B1

公开(公告)日：2001-05-29

申请号：US09316397

申请日：1999-05-21

申请人： Eyal Doron ,  Yariv Porat ,  Avi Penner

发明人： Eyal Doron ,  Yariv Porat ,  Avi Penner

IPC分类号： G08C1912

CPC分类号： A61B5/0535 ,  A61B5/0031 ,  A61B5/413 ,  A61B2562/028 ,  A61N1/37288 ,  G01F1/36 ,  G01F1/72 ,  H01L41/1132 ,  H04R17/00 ,  Y10S128/903

摘要： A telemetry system and method for providing spatial positioning information from within a patient's body are disclosed. The system includes at least one implantable telemetry unit which includes (a) at least one first transducer being for converting a power signal received from outside the body, into electrical power for powering the at least one implantable telemetry unit; (b) at least one second transducer being for receiving a positioning field signal being received from outside the body; and (c) at least one third transducer being for transmitting a locating signal transmittable outside the body in response to the positioning field signal.

摘要翻译： 公开了一种用于从患者体内提供空间定位信息的遥测系统和方法。 该系统包括至少一个可植入遥测单元，其包括（a）用于将从身体外部接收的功率信号转换成用于为至少一个可植入遥测单元供电的电力的至少一个第一换能器; （b）至少一个第二换能器，用于接收从身体外部接收的定位场信号; 和（c）至少一个第三换能器，用于响应于所述定位场信号，传送可发射到身体外部的定位信号。

公开(公告)号：US06198965B1

公开(公告)日：2001-03-06

申请号：US09312760

申请日：1999-05-17

申请人： Avi Penner ,  Eyal Doron ,  Yariv Porat

发明人： Avi Penner ,  Eyal Doron ,  Yariv Porat

IPC分类号： A61B500

CPC分类号： A61B5/0031 ,  A61B5/0535 ,  A61B5/413 ,  A61B2562/028 ,  A61N1/37252 ,  A61N1/37288 ,  H04R17/00

摘要： A telemetry system for monitoring a rejection reaction of a transplanted organ being transplanted within a patient's body is provided. The telemetry system includes (a) a telemetry control unit located outside the body of the patient; and (b) a telemetry monitoring unit implanted within the body of the patient, the telemetry monitoring unit including: (i) at least one acoustic transducer being for receiving an acoustic signal from the telemetry control unit and converting the acoustic signal into a first electrical signal, the at least one acoustic transducer further being for receiving a second electrical signal and converting the second electrical signal into a transmitted acoustic signal receivable by the telemetry monitoring unit; and (ii) a plurality of electrodes positionable in intimate contact with, or deep within, the transplanted organ and being in communication with the at least one acoustic transducer, the plurality of electrodes being for passing the first electrical signal through the transplanted organ for monitoring the electrical impedance thereof and further being for relaying the second electrical signal corresponding to the electrical impedance to the at least one acoustic transducer so as to enable the monitoring of the presence or absence of the rejection reaction.

摘要翻译： 提供了一种用于监测被移植在患者体内的移植器官的排斥反应的遥测系统。 遥测系统包括（a）位于患者体外的遥测控制单元; 遥测监测单元植入患者体内，遥测监测单元包括：（i）至少一个声换能器，用于接收来自遥测单元的声信号，并将声信号转换为第一电 信号，所述至少一个声换能器还用于接收第二电信号并将所述第二电信号转换成可由所述遥测监测单元接收的传输声信号; 和（ii）多个电极，其定位成与移植的器官紧密接触或深入移动的器官并且与至少一个声换能器连通，所述多个电极用于使第一电信号通过移植器官用于监测 其电阻抗并且还用于将对应于电阻抗的第二电信号中继到至少一个声换能器，以便能够监测是否存在排斥反应。

公开(公告)号：US06431175B1

公开(公告)日：2002-08-13

申请号：US09305442

申请日：1999-05-06

申请人： Avi Penner ,  Yariv Porat ,  Eyal Doron

发明人： Avi Penner ,  Yariv Porat ,  Eyal Doron

IPC分类号： A61B1900

CPC分类号： H01L41/1132 ,  A61B5/0031 ,  A61B5/413 ,  A61B2562/028 ,  A61N1/37288 ,  A61N5/1048 ,  A61N5/1071 ,  A61N2005/1072 ,  H04R17/00

摘要： A system for monitoring, directing and controlling the dose of radiation in a medical procedure for irradiating a specific region of a patient's body. In its generic form, the system includes at least one sensor being implantable within, or in proximity to, the specific region of the patient's body, the at least one sensor being for sensing at least one parameter associated with the radiation. The system further includes a relaying device which is in communication with the sensor(s). The relaying device serves for relaying the information outside of the patient's body.

摘要翻译： 用于在用于照射患者身体的特定区域的医疗程序中监测，指导和控制辐射剂量的系统。 在其通用形式中，该系统包括可植入在患者身体的特定区域内或附近的至少一个传感器，所述至少一个传感器用于感测与辐射相关联的至少一个参数。 该系统还包括与传感器通信的中继设备。 中继装置用于将病人身体外的信息中继。

公开(公告)号：US6140740A

公开(公告)日：2000-10-31

申请号：US553

申请日：1997-12-30

申请人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

发明人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

IPC分类号： A61B5/00 ,  A61B5/053 ,  G01F1/36 ,  G01F1/72 ,  H01L41/09 ,  H01L41/113 ,  H03H9/17 ,  H04R17/00 ,  H01L41/08

CPC分类号： A61B5/413 ,  A61B5/0031 ,  A61B5/0535 ,  G01F1/36 ,  G01F1/72 ,  H01L41/1132 ,  H04R17/00 ,  A61B2562/028 ,  A61N1/37288 ,  Y10S310/80

摘要： A miniature piezoelectric transducer element is provided, comprising; (a) a cell element having a cavity; (b) a flexible piezoelectric layer attached to the cell member, the piezoelectric layer having an external surface and an internal surface, the piezoelectric layer featuring such dimensions so as to enable fluctuations thereof at its resonance frequency upon impinging of an external acoustic wave; and (c) a first electrode attached to the external surface and a second electrode attached to the internal surface of the piezoelectric layer. At least one of the electrodes may be specifically shaped so as to provide a maximal electrical output, wherein the electrical output may be current, voltage or power. A preferred shape of the electrodes includes two cores interconnected by a connecting member. The transducer element may function as a transmitter. When used as a transmitter, the electrodes are electrically connected to an electrical circuit including a switching element for modulating the reflected acoustic wave by controllably changing the mechanical impedance of the piezoelectric layer according to the frequency of an electrical message signal arriving from an electronic member, such as a sensor. Third and fourth electrodes may be attached to the piezoelectric layer and the electrical circuit, such that the switching element alternately connects the electrodes in parallel and anti-parallel electrical connections so as to controllably change the mechanical impedance of the piezoelectric layer.

摘要翻译： 提供了一种微型压电传感器元件，包括： （a）具有空腔的电池元件; （b）安装在电池部件上的柔性压电体层，该压电体层具有外表面和内表面，该压电体层具有这样的尺寸，使其能够在外界声波入射时以其谐振频率发生波动; 和（c）附着到外表面的第一电极和附着在压电层的内表面上的第二电极。 电极中的至少一个可以被特别地成形为提供最大的电输出，其中电输出可​​以是电流，电压或功率。 电极的优选形状包括通过连接构件互连的两个芯。 换能器元件可以用作发射器。 当用作发射器时，电极电连接到包括用于通过可控地改变压电层的机械阻抗的调制反射声波的开关元件的电路，该电压根据从电子部件到达的电信号信号的频率， 例如传感器。 第三和第四电极可以附接到压电层和电路，使得开关元件以平行和反平行的电连接交替地连接电极，以便可控地改变压电层的机械阻抗。

公开(公告)号：US06504286B1

公开(公告)日：2003-01-07

申请号：US09691887

申请日：2000-10-20

申请人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

发明人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

IPC分类号： H01L4108

CPC分类号： A61B5/413 ,  A61B5/0031 ,  A61B5/0535 ,  A61B2562/028 ,  A61N1/37288 ,  G01F1/36 ,  G01F1/72 ,  H01L41/1132 ,  H04R17/00 ,  Y10S310/80

摘要： A miniature piezoelectric transducer element is provided, comprising: (a) a cell element having a cavity; (b) a flexible piezoelectric layer attached to the cell member, the piezoelectric layer having an external surface and an internal surface, the piezoelectric layer featuring such dimensions so as to enable fluctuations thereof at its resonance frequency upon impinging of an external acoustic wave; and (c) a first electrode attached to the external surface and a second electrode attached to the internal surface of the piezoelectric layer. At least one of the electrodes may be specifically shaped so as to provide a maximal electrical output, wherein the electrical output may be current, voltage or power. A preferred shape of the electrodes includes two cores interconnected by a connecting member. The transducer element may function as a transmitter. When used as a transmitter, the electrodes are electrically connected to an electrical circuit including a switching element for modulating the reflected acoustic wave by controllably changing the mechanical impedance of the piezoelectric layer according to the frequency of an electrical message signal arriving from an electronic member, such as a sensor. Third and fourth electrodes may be attached to the piezoelectric layer and the electrical circuit, such that the switching element alternately connects the electrodes in parallel and anti-parallel electrical connections so as to controllably change the mechanical impedance of the piezoelectric layer.

摘要翻译： 提供了一种微型压电换能器元件，包括：（a）具有空腔的电池元件; （b）安装在电池部件上的柔性压电体层，该压电体层具有外表面和内表面，该压电体层具有这样的尺寸，使其能够在外界声波入射时以其谐振频率发生波动; 和（c）附着到外表面的第一电极和附着在压电层的内表面上的第二电极。 电极中的至少一个可以被特别地成形为提供最大的电输出，其中电输出可​​以是电流，电压或功率。 电极的优选形状包括通过连接构件互连的两个芯。 换能器元件可以用作发射器。 当用作发射器时，电极电连接到包括用于通过可控地改变压电层的机械阻抗的调制反射声波的开关元件的电路，该电压根据从电子部件到达的电信号信号的频率， 例如传感器。 第三和第四电极可以附接到压电层和电路，使得开关元件以平行和反平行的电连接交替地连接电极，以便可控地改变压电层的机械阻抗。

公开(公告)号：US06237398B1

公开(公告)日：2001-05-29

申请号：US09161658

申请日：1998-09-29

申请人： Yariv Porat ,  Yosef Tsaliah ,  Eyal Doron

发明人： Yariv Porat ,  Yosef Tsaliah ,  Eyal Doron

IPC分类号： G01N1108

CPC分类号： A61B5/0535 ,  A61B5/0031 ,  A61B5/02158 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/413 ,  A61B2562/028 ,  A61N1/37288 ,  G01F1/36 ,  G01F1/72 ,  H01L41/1132 ,  H04R17/00

摘要： The present invention provides a system and method of quantifying flow, detecting a location of an obstruction and quantifying a degree of the obstruction in a pipe characterized in pulsatile flow. The method includes the steps of (a) attaching at least two spaced pressure sensors onto inner walls of the pipe; (b) using the at least two spaced pressure sensors for recording pressure records associated with each of the at least two pressure sensors within the pipe; and (c) using the pressure records for quantifying the pulsatile flow in the pipe, for detecting the location of the obstruction in the pipe and for quantifying the degree of the obstruction in the pipe.

摘要翻译： 本发明提供了一种量化流量的系统和方法，检测障碍物的位置并量化了以脉动流动为特征的管道中的阻塞程度。 该方法包括以下步骤：（a）将至少两个间隔开的压力传感器附接到管道的内壁上; （b）使用所述至少两个间隔开的压力传感器来记录与所述管道内的所述至少两个压力传感器中的每一个相关联的压力记录; 和（c）使用压力记录来量化管道中的脉动流量，用于检测管道中阻塞物的位置并用于量化管道中的阻塞程度。

公开(公告)号：US08647328B2

公开(公告)日：2014-02-11

申请号：US13604176

申请日：2012-09-05

申请人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

发明人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

IPC分类号： A61K9/22 ,  H04R17/00

CPC分类号： H01L41/04 ,  A61K9/0009 ,  A61K9/0024 ,  A61K9/0097

摘要： Devices and systems for transmitting information within a body are disclosed. An example system includes a signal generator configured for transmitting an acoustic interrogation signal, a sensor for sensing at least one parameter within the body and generating an electrical sensor signal, an acoustic transducer configured to convert a received acoustic interrogation signal into an electrical signal, and a switching element adapted to modulate a reflected acoustic wave from the acoustic transducer. The switching element is configured to controllably change the mechanical impedance of the acoustic transducer.

摘要翻译： 公开了用于在身体内传送信息的装置和系统。 示例性系统包括被配置为发送声讯讯信号的信号发生器，用于感测身体内的至少一个参数并产生电传感器信号的传感器，被配置为将接收到的声讯讯转换成电信号的声换能器，以及 适于调制来自声换能器的反射声波的开关元件。 开关元件被配置为可控地改变声换能器的机械阻抗。

公开(公告)号：US20120327747A1

公开(公告)日：2012-12-27

申请号：US13604176

申请日：2012-09-05

申请人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

发明人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

IPC分类号： H04R17/00

CPC分类号： H01L41/04 ,  A61K9/0009 ,  A61K9/0024 ,  A61K9/0097

摘要： Devices and systems for transmitting information within a body are disclosed. An example system includes a signal generator configured for transmitting an acoustic interrogation signal, a sensor for sensing at least one parameter within the body and generating an electrical sensor signal, an acoustic transducer configured to convert a received acoustic interrogation signal into an electrical signal, and a switching element adapted to modulate a reflected acoustic wave from the acoustic transducer. The switching element is configured to controllably change the mechanical impedance of the acoustic transducer.

摘要翻译： 公开了用于在身体内传送信息的装置和系统。 示例性系统包括被配置为发送声讯讯信号的信号发生器，用于感测身体内的至少一个参数并产生电传感器信号的传感器，被配置为将接收到的声讯讯转换成电信号的声换能器，以及 适于调制来自声换能器的反射声波的开关元件。 开关元件被配置为可控地改变声换能器的机械阻抗。

公开(公告)号：US20110178578A1

公开(公告)日：2011-07-21

申请号：US13075384

申请日：2011-03-30

申请人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

发明人： Yariv Porat ,  Yoseph Tsaliah ,  Eyal Doron

IPC分类号： A61N1/08

CPC分类号： H01L41/04 ,  A61K9/0009 ,  A61K9/0024 ,  A61K9/0097

摘要： Devices and systems for transmitting information within a body are disclosed. An example system includes a signal generator configured for transmitting an acoustic interrogation signal, a sensor for sensing at least one parameter within the body and generating an electrical sensor signal, an acoustic transducer coupled to the sensor and configured to convert a received acoustic interrogation signal into an electrical signal, and a switching element adapted to modulate a reflected acoustic wave from the acoustic transducer based on the electrical sensor signal. The switching element is configured to controllably change the mechanical impedance of the acoustic transducer based a parameter of the electrical sensor signal, such as frequency.

摘要翻译： 公开了用于在身体内传送信息的装置和系统。 示例性系统包括被配置为发送声讯讯信号的信号发生器，用于感测身体内的至少一个参数并产生电传感器信号的传感器，耦合到传感器并被配置为将接收到的声讯讯信号转换成 电信号，以及适于基于所述电传感器信号来调制来自所述声换能器的反射声波的开关元件。 开关元件被配置为基于诸如频率的电传感器信号的参数来可控地改变声换能器的机械阻抗。