公开(公告)号：US20170146512A1

公开(公告)日：2017-05-25

申请号：US15359253

申请日：2016-11-22

申请人： B. BRAUN AVITUM AG

发明人： MIRAN ALIC ,  Christof Strohhöfer ,  Waldemar Janik

IPC分类号： G01N33/49

CPC分类号： G01N33/49 ,  G01N21/274 ,  G01N21/33 ,  G01N33/70 ,  G01N33/96

摘要： A method for calibrating a measurement signal and/or for tracking a quantitative variable comprises the measuring of an analyte which exists in a solution with a certain concentration and has predetermined decay kinetics and the generating of a continuous measurement signal having decay kinetics at least corresponding to those of the analyte. The decay kinetics of the measurement signal and the decay kinetics of the analyte are correlated using at least one predetermined calibration point of both decay curves. Subsequent concentration values of the analyte are then calculated from the measurement signal.

公开(公告)号：US20240316255A1

公开(公告)日：2024-09-26

申请号：US18597078

申请日：2024-03-06

申请人： B. Braun Avitum AG

发明人： Waldemar Janik ,  Silvie Krause

IPC分类号： A61M1/36 ,  A61M1/16

CPC分类号： A61M1/3658 ,  A61M1/1603 ,  A61M2205/3368 ,  A61M2205/3375 ,  A61M2205/50 ,  A61M2230/207

摘要： A method automatically characterizes a vascular access of a dialysis patient who is or was connected to a dialysis machine, the vascular access being characterized dependent on a recirculation rate.

公开(公告)号：US20220342242A1

公开(公告)日：2022-10-27

申请号：US17642416

申请日：2020-09-17

申请人： B. Braun Avitum AG

发明人： Waldemar Janik

IPC分类号： G02F1/137 ,  A61M1/36 ,  G02F1/133

摘要： A medical device for extracorporeal blood treatment having a housing section that is designed such that is can reversibly change between two transparency states by applying an electrical voltage.

公开(公告)号：US20210244866A1

公开(公告)日：2021-08-12

申请号：US17268183

申请日：2019-08-28

申请人： B. Braun Avitum AG

发明人： Waldemar Janik ,  Eugen Schiller ,  Silvie Krause

IPC分类号： A61M1/16

摘要： A device and method of producing dialysis liquid for extracorporeal blood treatment. The device includes a main line for supplying water. An acidic and a basic fluid are introduced in specific dosages. The dosages are set by a control and regulation unit as a function of a chemical and/or physical parameter of the water/fluid mixture. The chemical and/or physical parameter is detected by a measuring device arranged at a section of the main conduit situated downstream of the introduction points for the acidic fluid and for the basic fluid. The control and regulation unit controls introduction of the acidic fluid and basic fluid so that only one of the acidic and basic fluids is introduced into the main conduit over a predetermined period or a predetermined interval. Delivery and introduction of the basic fluid and acidic fluid take place alternately.

公开(公告)号：US20220288291A1

公开(公告)日：2022-09-15

申请号：US17635869

申请日：2020-08-21

申请人： B. Braun Avitum AG

发明人： Waldemar Janik

IPC分类号： A61M1/16

摘要： A device and method for extracorporeal blood treatment, in particular for hemodialysis, and a method for the balance control of a dialysis fluid in an extracorporeal blood treatment. Sodium balancing can be implemented with improved accuracy during the blood treatment, because distorting effects in the conductivity measurement of the used dialysis fluid can be corrected by taking into account the loading of the used dialysis fluid with urophanic substances, which loading is sensed by an additional measuring apparatus.

公开(公告)号：US20220203002A1

公开(公告)日：2022-06-30

申请号：US17601825

申请日：2020-04-14

申请人： B. Braun Avitum AG

发明人： Nina Aldag ,  Waldemar Janik ,  Silvie Krause ,  Henrik Wolff

IPC分类号： A61M1/16 ,  G01N21/33 ,  G01N21/359 ,  G01N21/3577

摘要： An extracorporeal blood treatment machine includes a dialyzer and a sensor device downstream of the dialyzer on a dialysis fluid side. The machine is connected to a control and computing unit configured to qualitatively and quantitatively determine at least one preferably selected or selectable blood component in the used dialysis fluid. The control and computing unit is adapted to put the machine into a mode in which a dialysis fluid amount is confined within the dialyzer at least until the concentrations of the blood component on the dialysis fluid side and on the blood side of the dialyzer are in equilibrium, and thereupon to switch the machine into a mode in which the dialysis fluid flow is permitted to leave the dialyzer to feed the confined dialysis fluid amount as a dialysis fluid bolus to the sensor device for determining the blood component concentration contained in the bolus.

公开(公告)号：US10918775B2

公开(公告)日：2021-02-16

申请号：US16037702

申请日：2018-07-17

申请人： B. BRAUN AVITUM AG

发明人： Waldemar Janik

IPC分类号： A61M1/16 ,  A61M1/36

摘要： An apparatus and a method for extracorporeal blood treatment, especially for hemodialysis, wherein blood of a patient is flushed with a dialysate in a dialyzer and wherein a variable correlated with the plasma sodium concentration of the blood is measured. The composition of the dialysate then is adjusted in response to the variable measured so that the plasma sodium concentration of the blood at least at the end of the blood treatment has the same value as at the beginning. For measuring the variable correlated with the plasma sodium concentration of the blood, for example a bypass operation can be implemented in which the dialysate is guided past the dialyzer so that a residual volume on the side of the used dialysate at least partially adopts the concentration of the substances dissolved on the blood side.

公开(公告)号：US09423338B2

公开(公告)日：2016-08-23

申请号：US14691208

申请日：2015-04-20

申请人： B. BRAUN AVITUM AG

发明人： Miran Alic ,  Christof Strohhoefer ,  Waldemar Janik

IPC分类号： G01N21/00 ,  G01N21/25 ,  G01N21/31 ,  A61M1/16 ,  G01N21/85 ,  G01N21/33

CPC分类号： G01N21/255 ,  A61M1/1617 ,  A61M2205/3313 ,  G01N21/3103 ,  G01N21/33 ,  G01N21/85 ,  G01N2201/061 ,  G01N2800/347

摘要： Methods and apparatus are disclosed for determining a substance in a fluid excreted/extracted from the body or spent dialysate, e.g., for determining a quality measure for the dialysis, such as the concentration of selected toxic substances, and/or for determining a removed total quantity of uremic toxins during a dialysis with a dialysis apparatus. A concentration of a substance in the fluid may be determined by: detecting, by an absorption sensor, a first extinction signal of the fluid at an analysis wavelength at a defined first pH value of the fluid; adjusting, by a pH adjusting device, a second pH value of the fluid which differs from the first pH value; detecting, by the absorption sensor, a second extinction signal of the fluid at the analysis wavelength at the second pH value; and processing/comparing the two extinction signals for the first and the second pH values and determining an absolute concentration of the substance dissolved in the fluid.

摘要翻译： 公开了用于确定从身体排出/提取的流体中的物质或废透析液的方法和装置，例如用于确定透析的质量测量，例如所选择的有毒物质的浓度和/或用于确定去除的总量 用透析仪透析期间尿毒症毒素的量。 流体中物质的浓度可以通过以下方式确定：通过吸收传感器在流体的确定的第一pH值下以分析波长检测流体的第一消光信号; 通过pH调节装置调节与第一pH值不同的流体的第二pH值; 通过吸收传感器检测处于第二pH值的分析波长处的流体的第二消光信号; 以及处理/比较第一和第二pH值的两个消光信号，并确定溶解在流体中的物质的绝对浓度。

公开(公告)号：US20240009445A1

公开(公告)日：2024-01-11

申请号：US18035038

申请日：2021-11-03

申请人： B. Braun Avitum AG

发明人： Waldemar Janik

IPC分类号： A61M60/284 ,  A61M60/109

CPC分类号： A61M60/284 ,  A61M60/109

摘要： A peristaltic pump includes a housing and a rotor that rotates about a rotor axis. The rotor has a rotor body and a pump. The housing has a cut-out in which the rotor is accommodated and a support surface extending about the rotor axis. The support surface supports a tube segment that is introducible between the rotor and support surface. The rotor has a first element for manually actuating the rotor and a first portion for applying a manual rotation actuation force. The first element is mounted on the rotor body and is movable relative to the rotor body between a first position, in which the first portion is spaced from the rotor axis by a first length, and a second position, in which the first portion is spaced from the rotor axis by a second length, the second length being greater than the first length.

公开(公告)号：US20220313878A1

公开(公告)日：2022-10-06

申请号：US17631580

申请日：2020-08-17

申请人： B. Braun Avitum AG

发明人： Florian Bauer ,  Waldemar Janik

IPC分类号： A61M1/14

摘要： A holding device for holding and fixing at least one electronic terminal device, in particular of the entertainment electronics type, during a medical treatment, more particularly dialysis treatment. The terminal device is or can be attached to a medical treatment apparatus, such as a dialysis machine, or to a patient bed. The holding device includes an integrated charging unit to supply the held and/or fixed electronic terminal device with power, more particularly from the medical treatment apparatus, with a protection circuit being integrated in the holding device to detect a defect of a terminal device that has just been connected. A charging unit includes an integral power supply unit on a dialysis machine or patient bed having a holding device.