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    Sheared pad detection systems and methods
    3.
    发明授权
    Sheared pad detection systems and methods 有权

    公开(公告)号：US11371944B2

    公开(公告)日：2022-06-28

    申请号：US16468334

    申请日：2017-12-15

    Applicant: Beckman Coulter, Inc.

    Inventor： Jindan Zhou ,  Carlos Ramirez ,  Patricio Vidal ,  Christophe Godefroy ,  Gregory Yeager ,  Jorge Leon

    IPC: G01N21/78 ,  G01N21/77 ,  G06V10/22 ,  G06T7/00 ,  G06V10/56

    Abstract: Embodiments of the present invention encompass systems and methods for detecting the presence of a test pad on a test strip. Exemplary techniques involve receiving a test strip having at least one test pad, where individual test pads have a pad width with ink disposed on two ink zones at two opposing sides of the width of the pad, illuminating the at least one test pad with a light source, detecting reflected signals from the test pad, generating an image comprising of pixels of the two ink zones based on the reflected signals, detecting the presence of each of the ink zones by comparing the number of consecutive pixels against a predetermined threshold, and determining the presence of the test pad on the test strip if two ink zones are detected within the pad width.

    Systems and methods to determine the age of cells
    5.
    发明授权
    Systems and methods to determine the age of cells 有权

    公开(公告)号：US10739357B2

    公开(公告)日：2020-08-11

    申请号：US15510612

    申请日：2015-09-11

    Applicant: Beckman Coulter, Inc.

    Inventor： Andreas Van Agthoven ,  Fabrice Malergue ,  Christophe Godefroy ,  Enrique Rabellino

    IPC: G01N33/80 ,  G01N33/72 ,  G01N15/14 ,  G01N33/49 ,  G01N33/58 ,  G01N15/00

    Abstract: Systems and methods are provided for determining the age of cellular hemoglobin in individual red blood cells in a blood sample by determining the percentage of HbA1c. In embodiments, a method includes measuring side scatter and fluorescence of the individual red blood cells and identifying immature red blood cells and mature red blood cells from the side scatter and fluorescence measurement. In embodiments, data collected includes the exact number of red blood cells, the fraction limits in fluorescence and side scatter units, the mean value of each fraction in fluorescence and side scatter units, the mean FL1 values per fraction in arbitrary units and the mean side scatter values per fraction in arbitrary units. In embodiments, a method also includes deriving a HbA1c content from the measured mean fluorescence of the individual red blood cells and determining the percentage of HbA1c from the HbA1c content and the hemoglobin content of the red blood cells.

    IMMATURE PLATELET ENUMERATION SYSTEMS AND METHODS
    9.
    发明申请
    IMMATURE PLATELET ENUMERATION SYSTEMS AND METHODS 有权
    实验室计量系统和方法

    公开(公告)号：US20140186874A1

    公开(公告)日：2014-07-03

    申请号：US14142369

    申请日：2013-12-27

    Applicant: Beckman Coulter, Inc.

    Inventor： Jiuliu Lu ,  Phaisit Chewputtanagul ,  Christophe Godefroy ,  Patricio Vidal ,  John Riley

    IPC: G01N33/80

    CPC classification number: G01N33/80 ,  G01N15/0211 ,  G01N15/10 ,  G01N15/12 ,  G01N15/1459 ,  G01N2015/0084

    Abstract: Embodiments of the present invention encompass automated systems and methods for analyzing immature platelet parameters in an individual based on a biological sample obtained from blood of the individual. Exemplary techniques involve correlating aspects of direct current (DC) impedance, radiofrequency (RF) conductivity, and/or light measurement data obtained from the biological sample with an evaluation of immature platelet conditions in the individual.

    Abstract translation: 本发明的实施方案包括基于从个体的血液获得的生物样品来分析个体中的未成熟血小板参数的自动化系统和方法。 示例性技术涉及将从生物样品获得的直流（DC）阻抗，射频（RF）电导率和/或光测量数据的方面与个体中未成熟血小板状况的评估相关联。

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