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公开(公告)号：US11944263B2
公开(公告)日：2024-04-02
申请号：US16571828
申请日：2019-09-16
发明人： Sean P. Fleury , Gary S. Kappel , Norman C. May , Dane T. Seddon , Mark D. Wood , Peter L. Dayton
CPC分类号： A61B1/00071 , A61B1/00128 , A61B1/0055 , A61B17/29 , A61M25/0043 , A61M39/12 , A61B2017/00314 , A61B2017/00323 , A61B2017/0034 , A61B2017/00464 , A61B2017/00473 , A61B2017/00477 , A61B2017/2905
摘要： Embodiments of the disclosure include methods and systems for attaching an articulation section. In an embodiment, a medical instrument includes a first tubular member including a first end. The medical instrument also includes a second tubular member including a first end. The second tubular member includes a plurality of layers including an inner layer and a first layer including a fluorinated material. The inner layer includes a first section disposed under the first layer and a second section extending out from under the first layer. A portion of the first tubular member overlaps and is bonded to at least a portion of the second section of the inner layer of the second tubular member.
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公开(公告)号：US10195061B2
公开(公告)日：2019-02-05
申请号：US14919688
申请日：2015-10-21
摘要： A stent covering includes a polymeric tube having a first end, a second end and a length extending therebetween, the polymeric tube including an inner surface defining a lumen and an outer surface. A plurality of tissue ingrowth features are formed on the outer surface of the polymeric tube, at least some of the plurality of tissue ingrowth features including polymeric loops that extend above the outer surface such that, once implanted, tissue can grow between the outer surface and the polymeric loops. A stent may include such a stent covering.
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公开(公告)号：US09764067B2
公开(公告)日：2017-09-19
申请号：US14210612
申请日：2014-03-14
发明人： Sean P. Fleury , Mark D. Wood , Dane T. Seddon , Laura Elizabeth Firstenberg , Paul Smith , Gary J. Leanna , Claude O. Clerc , James Weldon , Steven E. Walak
CPC分类号： A61L31/14 , A61F2/0077 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/043 , A61F2230/0067 , A61F2230/0091 , A61F2250/0026 , A61F2250/0039 , A61F2250/0051 , A61F2250/0056 , A61L31/10 , A61L2400/12 , A61L2400/18 , C08L27/18 , C08L23/12
摘要： A method for reducing mucus accumulation in an airway including disposing an implantable device within an airway, wherein the implantable device has a first end, a second end, and an inner surface defining a lumen extending from the first end to the second end; wherein at least a portion of the inner surface has a hydrophobic polymer coating thereon, wherein a polymer coating surface has dynamic water contact angles of 145 degrees or greater; and wherein the implantable device is constructed and arranged to maintain patency of the airway; wherein accumulation of mucus is reduced as compared to a similar implantable device without the hydrophobic portion of the inner surface. An implantable medical device having a superhydrophobic surface and a method of making an implantable medical device having a superhydrophobic surface are also provided. An implantable medical device having a micropatterned surface with enhanced adhesion to tissue, optionally in combination with other region(s) having a superhydrophobic surface and a method of making such a device. Methods and devices for prevention of bacterial adhesion to implanted medical devices.
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公开(公告)号：US09579185B2
公开(公告)日：2017-02-28
申请号：US14190343
申请日：2014-02-26
发明人： Mark Wood , Dane T. Seddon , Sean Fleury , Daniel Ross , Burns P. Doran
CPC分类号： A61F2/915 , A61F2/04 , A61F2/06 , A61F2/2418 , A61F2/82 , A61F2/91 , A61F2002/044 , A61F2002/045 , A61F2002/046 , A61F2230/0006 , A61F2230/0008 , A61F2250/0036 , A61F2250/0098
摘要： Implantable medical devices and methods for making and using the same are disclosed. An example implantable medical device may include a stent having a first configuration and a second expanded configuration. The stent may define a plurality of nodes. The stent may have a cover member disposed adjacent the nodes. The cover member may be configured to cover at least some of the nodes when the stent is in the expanded configuration.
摘要翻译： 公开了可植入医疗装置及其制造和使用方法。 可植入医疗装置的示例可以包括具有第一构造和第二扩张构型的支架。 支架可以限定多个节点。 支架可以具有邻近节点设置的盖构件。 当支架处于展开构型时，盖构件可构造成覆盖至少一些节点。
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公开(公告)号：US20140277442A1
公开(公告)日：2014-09-18
申请号：US14210595
申请日：2014-03-14
发明人： Dane T. Seddon , Sean P. Fleury , Mark D. Wood , Gary S. Kappel
CPC分类号： A61F2/848 , A61F2/04 , A61F2002/8483 , A61L31/14
摘要： The invention is directed to an anti-migratory stent comprising a tubular structure having an exterior surface and a plurality of protrusions provided on the exterior surface. The plurality of protrusions includes a first set of protrusions and a second set of protrusions. Each of the first and second set of protrusions includes a base and an apex. The apex of each of the first set of protrusions is offset from the base of the first set of protrusions in a direction opposite a direction of offset of the apex of each of the second set of protrusions from the base of the second set of protrusions.
摘要翻译： 本发明涉及一种抗迁移支架，其包括具有外表面和设置在外表面上的多个突起的管状结构。 多个突起包括第一组突起和第二组突起。 第一和第二组突起中的每一个包括基部和顶点。 第一组突起中的每一个的顶点在与第二组突起的基底的每个第二组突起的顶点的偏移方向相反的方向上偏离第一组突起的基部。
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公开(公告)号：US20150073529A1
公开(公告)日：2015-03-12
申请号：US14483967
申请日：2014-09-11
发明人： Sean P. Fleury , Dane T. Seddon , Daniel Ross , Burns P. Doran
CPC分类号： A61F2/07 , A61F2/848 , A61F2/915 , A61F2002/91558 , A61F2002/91575 , A61F2220/0008 , A61F2230/0013 , A61F2230/005 , A61F2240/001 , A61F2250/0039 , A61L31/10 , B05D1/02 , B05D3/007
摘要： An endoprosthesis, such as a stent, having anti-migration features. The endoprosthesis includes an expandable tubular framework including a plurality of strut rows and a plurality of connectors extending across interstices between adjacent strut rows and interconnecting adjacent strut rows. The strut rows have an outer diameter in an expanded state and the connectors extend radially outward beyond the outer diameter of the strut rows in the expanded state. The connectors are configured to engage a wall of a body lumen in the expanded state to inhibit migration of the endoprosthesis in the body lumen. The endoprosthesis may include a polymeric cover covering the strut rows and spanning the interstices between adjacent strut rows, while a space between the connectors and the strut rows to which the connectors are interconnected with is devoid of the polymeric cover to permit tissue ingrowth around the connectors.
摘要翻译： 具有抗迁移特征的内置假体，例如支架。 内假体包括可扩展的管状框架，其包括多个支柱行和跨越相邻支柱之间的间隙延伸并且互连相邻支柱行的多个连接器。 支柱行具有展开状态的外径，并且连接器在展开状态下径向向外延伸超过支柱行的外径。 连接器构造成接合膨胀状态下的体腔的壁以抑制体内腔内的假体的移动。 内置假体可以包括覆盖支柱行并横跨相邻支柱之间的间隙的聚合物盖，而连接器和连接器互连的支柱之间的空间没有聚合物盖以允许组织向内延伸连接器 。
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公开(公告)号：US20140277443A1
公开(公告)日：2014-09-18
申请号：US14210612
申请日：2014-03-14
发明人： Sean P. Fleury , Mark D. Wood , Dane T. Seddon , Laura Elizabeth Firstenberg , Paul Smith , Gary J. Leanna , Claude O. Clerc , James Weldon , Steven E. Walak
CPC分类号： A61L31/14 , A61F2/0077 , A61F2/07 , A61F2/82 , A61F2/86 , A61F2002/043 , A61F2230/0067 , A61F2230/0091 , A61F2250/0026 , A61F2250/0039 , A61F2250/0051 , A61F2250/0056 , A61L31/10 , A61L2400/12 , A61L2400/18 , C08L27/18 , C08L23/12
摘要： A method for reducing mucus accumulation in an airway including disposing an implantable device within an airway, wherein the implantable device has a first end, a second end, and an inner surface defining a lumen extending from the first end to the second end; wherein at least a portion of the inner surface has a hydrophobic polymer coating thereon, wherein a polymer coating surface has dynamic water contact angles of 145 degrees or greater; and wherein the implantable device is constructed and arranged to maintain patency of the airway; wherein accumulation of mucus is reduced as compared to a similar implantable device without the hydrophobic portion of the inner surface. An implantable medical device having a superhydrophobic surface and a method of making an implantable medical device having a superhydrophobic surface are also provided. An implantable medical device having a micropatterned surface with enhanced adhesion to tissue, optionally in combination with other region(s) having a superhydrophobic surface and a method of making such a device. Methods and devices for prevention of bacterial adhesion to implanted medical devices.
摘要翻译： 一种用于减少气道中的粘液累积的方法，包括在气道内设置可植入装置，其中所述可植入装置具有第一端，第二端和限定从所述第一端延伸到所述第二端的内腔的内表面; 其中所述内表面的至少一部分在其上具有疏水聚合物涂层，其中聚合物涂层表面具有145度或更大的动态水接触角; 并且其中所述可植入装置被构造和布置成保持所述气道的通畅; 其中与不具有内表面的疏水部分的类似可植入装置相比，粘液的积聚减少。 还提供了具有超疏水表面的可植入医疗装置和制造具有超疏水表面的可植入医疗装置的方法。 一种植入式医疗装置，其具有对组织增强的附着力的微图案化表面，任选地与具有超疏水表面的其它区域组合，以及制造这种装置的方法。 用于防止植入医疗器械细菌粘附的方法和装置。
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公开(公告)号：US10456011B2
公开(公告)日：2019-10-29
申请号：US15003415
申请日：2016-01-21
发明人： Sean P. Fleury , Gary S. Kappel , Norman C. May , Dane T. Seddon , Mark D. Wood , Peter L. Dayton
摘要： Embodiments of the disclosure include methods and systems for attaching an articulation section. In an embodiment, a medical instrument includes a first tubular member including a first end. The medical instrument also includes a second tubular member including a first end. The second tubular member includes a plurality of layers including an inner layer and a first layer including a fluorinated material. The inner layer includes a first section disposed under the first layer and a second section extending out from under the first layer. A portion of the first tubular member overlaps and is bonded to at least a portion of the second section of the inner layer of the second tubular member.
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公开(公告)号：US10130498B2
公开(公告)日：2018-11-20
申请号：US14919697
申请日：2015-10-21
发明人： Sean P. Fleury , Dane T. Seddon , Jason Weiner
摘要： An endoprosthesis may include an expandable tubular framework expandable from a compressed state to an expanded state and include a plurality of strut rows, wherein adjacent strut rows define interstices spacing the adjacent strut rows apart, and a plurality of connectors extending across the interstices and interconnecting adjacent strut rows, at least some of the plurality of connectors defining a flexible hinge portion. The lengths of the interstices between adjacent strut rows may vary along the length of the expandable tubular framework. The plurality of connectors extend radially outward beyond an outer diameter of the plurality of strut rows in the expanded state. The plurality of connectors are configured to engage a wall of a body lumen in the expanded state to inhibit migration of the endoprosthesis subsequent implanting the endoprosthesis in the body lumen.
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公开(公告)号：US10117763B2
公开(公告)日：2018-11-06
申请号：US14660468
申请日：2015-03-17
发明人： Sean P. Fleury , Dane T. Seddon , Barry Weitzner
摘要： A stent of the present disclosure has a variable radial force along the longitudinal length of the stent. In particular, the radial force of the center is greater than the radial force of the ends of the stent. Without being bound by theory, the radial force is affected by the strut angle θ, the wall thickness t, the number of strut pairs, and combinations thereof. In one aspect of the present disclosure, the stent has a variable strut angle θ, a variable wall thickness t, and a variable number of strut pairs. By adjusting the strut angle θ, the wall thickness t, and the number of strut pairs of the serpentine bands, the stent will have a variable radial force without the need for additional processing steps.
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