-
公开(公告)号：US20090149656A1
公开(公告)日：2009-06-11
申请号：US12189089
申请日：2008-08-08
IPC分类号： C07D401/00 , C07C69/52
CPC分类号： A61K49/0019 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/025 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , G01N33/542 , G01N33/543 , G01N33/582 , G01N33/66 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
摘要翻译： 本发明涉及一种改进的光学方法和光学感测装置，用于确定水性介质中体外和/或体内多羟基取代的有机分子的水平。 检测范围在约400和800nm之间。 特别地，在哺乳动物中实施感官设计以确定糖水平。 具体地说，在糖如果糖或葡萄糖的存在下，将染料与共轭含氮杂环芳族硼酸取代的双鎓化合物组合。 紫罗兰是优选的芳族共轭含氮硼酸取代的化合物。 该方法对于测定人的糖含量是有用的。
-
公开(公告)号：US06653141B2
公开(公告)日：2003-11-25
申请号：US09731325
申请日：2000-12-05
IPC分类号： G01N2164
CPC分类号： G01N21/6408 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro in aqueous or organic media. Specifically, a dye is combined with an conjugated nitrogen-containing aromatic heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen containing boronic acid substituted compounds. The method is useful to determine sugar levels in fermentation and process streams.
摘要翻译： 本发明涉及用于在水性或有机介质中体外测定多羟基取代的有机分子水平的改进的光学方法和光学感测装置。 具体地说，在糖如果糖或葡萄糖的存在下，将染料与共轭含氮芳族杂环芳族硼酸取代的双鎓化合物组合。 紫罗兰是优选的含芳族共轭氮的硼酸取代的化合物。 该方法可用于测定发酵和过程流中的糖含量。
-
公开(公告)号：US07968714B2
公开(公告)日：2011-06-28
申请号：US12189089
申请日：2008-08-08
IPC分类号： C07F5/02 , C07D401/04
CPC分类号： A61K49/0019 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/025 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , G01N33/542 , G01N33/543 , G01N33/582 , G01N33/66 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
摘要翻译： 本发明涉及一种改进的光学方法和光学感测装置，用于确定水性介质中体外和/或体内多羟基取代的有机分子的水平。 检测范围在约400和800nm之间。 特别地，在哺乳动物中实施感官设计以确定糖水平。 具体地说，在糖如果糖或葡萄糖的存在下，将染料与共轭含氮杂环芳族硼酸取代的双鎓化合物组合。 紫罗兰是优选的芳族共轭含氮硼酸取代的化合物。 该方法对于测定人的糖含量是有用的。
-
公开(公告)号：US08951503B2
公开(公告)日：2015-02-10
申请号：US12189094
申请日：2008-08-08
IPC分类号： A61B10/00 , A61B8/00 , A61B5/00 , A61K49/00 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/02 , C09K9/02 , G01N33/542 , G01N33/543 , G01N33/58 , G01N33/66
CPC分类号： A61K49/0019 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/025 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , G01N33/542 , G01N33/543 , G01N33/582 , G01N33/66 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
摘要翻译： 本发明涉及一种改进的光学方法和光学感测装置，用于确定水性介质中体外和/或体内多羟基取代的有机分子的水平。 检测范围在约400和800nm之间。 特别地，在哺乳动物中实施感官设计以确定糖水平。 具体地说，在糖如果糖或葡萄糖的存在下，将染料与共轭含氮杂环芳族硼酸取代的双鎓化合物组合。 紫罗兰是优选的芳族共轭含氮硼酸取代的化合物。 该方法对于测定人的糖含量是有用的。
-
公开(公告)号：US08394357B2
公开(公告)日：2013-03-12
申请号：US12189082
申请日：2008-08-08
CPC分类号： A61K49/0019 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/025 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , G01N33/542 , G01N33/543 , G01N33/582 , G01N33/66 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
-
公开(公告)号：US20090148956A1
公开(公告)日：2009-06-11
申请号：US12189094
申请日：2008-08-08
IPC分类号： G01N21/64
CPC分类号： A61K49/0019 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/025 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , G01N33/542 , G01N33/543 , G01N33/582 , G01N33/66 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
-
公开(公告)号：US20090148344A1
公开(公告)日：2009-06-11
申请号：US12189082
申请日：2008-08-08
IPC分类号： G01N21/64
CPC分类号： A61K49/0019 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/025 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , G01N33/542 , G01N33/543 , G01N33/582 , G01N33/66 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
-
公开(公告)号：US07470420B2
公开(公告)日：2008-12-30
申请号：US11296898
申请日：2005-12-07
CPC分类号： A61K49/0019 , B82Y5/00 , B82Y10/00 , B82Y15/00 , B82Y30/00 , C07D213/82 , C07F5/025 , C09K9/02 , C09K2211/1007 , C09K2211/1011 , C09K2211/1029 , G01N33/542 , G01N33/543 , G01N33/582 , G01N33/66 , Y10T436/144444
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vitro and/or in vivo in aqueous media. The range of detection is between about 400 and 800 nm. In particular, a sensory devise is implemented in a mammal to determine sugar levels. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
摘要翻译： 本发明涉及一种改进的光学方法和光学感测装置，用于确定水性介质中体外和/或体内多羟基取代的有机分子的水平。 检测范围在约400和800nm之间。 特别地，在哺乳动物中实施感官设计以确定糖水平。 具体地说，在糖如果糖或葡萄糖的存在下，将染料与共轭含氮杂环芳族硼酸取代的双鎓化合物组合。 紫罗兰是优选的芳族共轭含氮硼酸取代的化合物。 该方法对于测定人的糖含量是有用的。
-
公开(公告)号：US06627177B2
公开(公告)日：2003-09-30
申请号：US09731323
申请日：2000-12-05
IPC分类号： A61B1000
CPC分类号： G01N33/52
摘要： The present invention concerns an improved optical method and optical sensing device for determining the levels of polyhydroxyl-substituted organic molecules in vivo in aqueous media. Specifically, a dye is combined with a conjugated nitrogen-containing heterocyclic aromatic boronic acid-substituted bis-onium compound in the presence of a sugar, such as fructose or glucose. The viologens are preferred as the aromatic conjugated nitrogen-containing boronic acid substituted compounds. The method is useful to determine sugar levels in a human being.
-
10.发明申请公开(公告)号：US20080188725A1
公开(公告)日：2008-08-07
申请号：US12027158
申请日：2008-02-06
IPC分类号： A61B5/1455
CPC分类号： A61B5/14532 , A61B5/0071 , A61B5/14552 , A61B5/1459 , A61B5/7203 , G01N21/6428 , G01N21/645
摘要： Novel optical devices, methods and systems relating to the detection of glucose, and more particularly to real-time glucose monitoring, are disclosed herein. More particularly, various hardware and methodological means are disclosed for ratiometric correction of optical glucose measurements for artifacts of optical systems.
摘要翻译： 本文公开了与葡萄糖检测有关的新型光学器件，方法和系统，更具体地涉及实时葡萄糖监测。 更具体地，公开了用于光学系统的伪像的光学葡萄糖测量的比例校正的各种硬件和方法手段。
-
-
-
-
-
-
-
-
-
搜索结果
93 条记录 (耗时 0.036 秒)