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1.发明申请Method and Systems for Controlling Ultrafiltration Using Central Venous Pressure Measurements 审中-公开使用中央静脉压测量控制超滤的方法和系统公开(公告)号：US20100331754A1
公开(公告)日：2010-12-30
申请号：US12875888
申请日：2010-09-03
Applicant: Barry N. Fulkerson , James R. Braig , Victor Gura
Inventor： Barry N. Fulkerson , James R. Braig , Victor Gura
IPC: A61M1/16
CPC classification number: A61M1/3653 , A61B5/02152 , A61B5/412 , A61M1/3659 , A61M1/3661 , A61M2230/30 , B01D61/22 , B01D61/32
Abstract: The volume of fluid removed from a patient during ultrafiltration is controlled automatically on the basis of central venous pressure (CVP) measurements. In one embodiment, a central venous catheter (CVC) is used for accessing blood during dialysis. A sensor located at the tip of the catheter or inside the dialysis machine is used to periodically measure CVP. CVP feedback data helps prevent the excessive removal of fluids from the patient.
Abstract translation: 基于中心静脉压（CVP）测量自动控制在超滤期间从患者移除的流体体积。 在一个实施例中，中心静脉导管（CVC）用于在透析期间接近血液。 位于导管尖端或透析机内部的传感器用于定期测量CVP。 CVP反馈数据有助于防止患者过度去除液体。
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2.发明申请Methods and Systems for Controlling Ultrafiltration Using Central Venous Pressure Measurements 审中-公开使用中央静脉压测量法控制超滤的方法和系统公开(公告)号：US20090101577A1
公开(公告)日：2009-04-23
申请号：US12238055
申请日：2008-09-25
Applicant: Barry N. Fulkerson , James R. Braig , Victor Gura
Inventor： Barry N. Fulkerson , James R. Braig , Victor Gura
CPC classification number: A61M1/3653 , A61B5/02152 , A61B5/412 , A61M1/3659 , A61M1/3661 , A61M2230/30 , B01D61/22 , B01D61/32
Abstract: The volume of fluid removed from a patient during ultrafiltration is controlled automatically on the basis of central venous pressure (CVP) measurements. In one embodiment, a central venous catheter (CVC) is used for accessing blood during dialysis. A sensor located at the tip of the catheter or inside the dialysis machine is used to periodically measure CVP. CVP feedback data helps prevent the excessive removal of fluids from the patient.
Abstract translation: 基于中心静脉压（CVP）测量自动控制在超滤期间从患者移除的流体体积。 在一个实施例中，中心静脉导管（CVC）用于在透析期间接近血液。 位于导管尖端或透析机内部的传感器用于定期测量CVP。 CVP反馈数据有助于防止患者过度去除液体。
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公开(公告)号：US20210369930A1
公开(公告)日：2021-12-02
申请号：US17333832
申请日：2021-05-28
Applicant: Victor Gura
Inventor： Victor Gura
Abstract: The present disclosure includes systems and methods for hemodialysis, such as including a first dialysis module and an auxiliary module detachably connectable to the first dialysis module. The first dialysis module can include a dialyzer, a blood circuit, a dialysate circuit, and a sorbent. The auxiliary module can include an ultrafiltrate collector operably couplable to the dialysate circuit for removing excess fluid therefrom.
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公开(公告)号：US20120031825A1
公开(公告)日：2012-02-09
申请号：US13239000
申请日：2011-09-21
Applicant: Victor Gura , Carlos Jacobo Ezon , Mesoud Beizai
Inventor： Victor Gura , Carlos Jacobo Ezon , Mesoud Beizai
CPC classification number: B01D19/0031 , A61M1/1658 , A61M1/1696
Abstract: The present invention is directed to degassing devices for dialysate circuits. One embodiment has a first housing and a second housing positioned within the first housing in an annular relationship. A second embodiment comprises a dialysate regeneration system with urease, a dialyzer, and a housing with an external wall, where the external wall is exposed to atmosphere and comprises a material that passes gas but does not pass liquid and where the housing is positioned between the urease and dialyzer.
Abstract translation: 本发明涉及用于透析液回路的脱气装置。 一个实施例具有以环形关系定位在第一壳体内的第一壳体和第二壳体。 第二个实施方案包括具有尿素酶的透析液再生系统，透析器和具有外壁的壳体，其中外壁暴露于大气中并且包括通过气体但不通过液体的材料，并且所述壳体位于 脲酶和透析器。
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公开(公告)号：US08034161B2
公开(公告)日：2011-10-11
申请号：US12355128
申请日：2009-01-16
Applicant: Victor Gura , Carlos Jacobo Ezon , Masoud Beizai
Inventor： Victor Gura , Carlos Jacobo Ezon , Masoud Beizai
CPC classification number: B01D19/0031 , A61M1/1658 , A61M1/1696
Abstract: The present invention is directed to degassing devices for dialysate circuits. One embodiment has a first housing and a second housing positioned within the first housing in an annular relationship. A second embodiment comprises a dialysate regeneration system with urease, a dialyzer, and a housing with an external wall, where the external wall is exposed to atmosphere and comprises a material that passes gas but does not pass liquid and where the housing is positioned between the urease and dialyzer.
Abstract translation: 本发明涉及用于透析液回路的脱气装置。 一个实施例具有以环形关系定位在第一壳体内的第一壳体和第二壳体。 第二个实施方案包括具有尿素酶的透析液再生系统，透析器和具有外壁的壳体，其中外壁暴露于大气中并且包括通过气体但不通过液体的材料，并且所述壳体位于 脲酶和透析器。
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Patent Agency Ranking
6.发明申请DUAL-VENTRICLE PUMP CARTRIDGE, PUMP, AND METHOD OF USE IN A WEARABLE CONTINUOUS RENAL REPLACEMENT THERAPY DEVICE 审中-公开双通道泵盒，泵，以及使用在可接受的连续的肾脏替代治疗装置中的方法公开(公告)号：US20110142700A1
公开(公告)日：2011-06-16
申请号：US12946590
申请日：2010-11-15
Applicant: Victor Gura , Edmond Rambod
Inventor： Victor Gura , Edmond Rambod
IPC: F04B43/12
CPC classification number: A61M1/1696 , A61M1/1006 , A61M1/1039 , A61M1/1053 , A61M1/1645 , A61M1/3472 , A61M1/3672 , A61M2205/3389 , A61M2205/8212 , A61M2205/8237 , A61M2209/088 , F04B43/082 , F04B43/086 , F04B43/09
Abstract: A dual channel pulsatile pump for use with a completely wearable renal replacement device is provided.
Abstract translation: 提供了一种用于完全穿戴式肾脏替换装置的双通道脉动泵。
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公开(公告)号：US07828761B2
公开(公告)日：2010-11-09
申请号：US11830695
申请日：2007-07-30
Applicant: Victor Gura , Edmond Rambod
Inventor： Victor Gura , Edmond Rambod
CPC classification number: B01D61/18 , A61M1/16 , A61M1/1696 , A61M1/34 , A61M1/3403 , A61M1/3496 , A61M2205/3331 , A61M2205/8206 , A61M2209/082 , A61M2209/088 , B01D61/145
Abstract: An ultrafiltration device adapted to be worn on a portion of the body of a patient includes a blood inlet tube leading from a first blood vessel, a blood pump, an anticoagulant reservoir for infusing anticoagulants into the blood, a blood filter including a substrate through which the blood is circulated and filtered, a fluid bag for storing the excess fluid and a blood outlet tube leading to a second blood vessel.
Abstract translation: 适于佩戴在患者身体的一部分上的超滤装置包括从第一血管，血泵，用于将抗凝血剂注入血液中的抗凝剂储存器引导的血液入口管，包含基底的血液过滤器， 血液循环和过滤，用于储存多余流体的流体袋和通向第二血管的出血管。
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公开(公告)号：US20080006570A1
公开(公告)日：2008-01-10
申请号：US11778254
申请日：2007-07-16
Applicant: Victor Gura , Hans-Dietrich Polaschegg
Inventor： Victor Gura , Hans-Dietrich Polaschegg
CPC classification number: B01D61/00 , A61M1/3679 , B01J20/2805
Abstract: A cartridge for treating medical or biological fluid includes a first cap having an inlet for the fluid, a container including a plurality of compartments and a second cap including an outlet for the fluid, wherein each compartment contains a plurality of particles, wherein the fluid is adapted to flow through the compartments and react with the plurality of particles.
Abstract translation: 用于治疗医疗或生物流体的药筒包括具有用于流体的入口的第一帽，包含多个隔室的容器和包括用于流体的出口的第二帽，其中每个隔室包含多个颗粒，其中流体为 适于流过隔间并与多个颗粒反应。
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公开(公告)号：US20220241477A1
公开(公告)日：2022-08-04
申请号：US17650006
申请日：2022-02-04
Applicant: Victor Gura
Inventor： Victor Gura
Abstract: Various embodiments disclosed relate to a portable system for continuous renal replacement therapy. The present disclosure includes a system including a dialyzer, a blood circuit, a dialysate circuit, a cannister, a pump, and a housing. The housing can encase the system, including the dialyzer, circuits, cannister and pump. The system can be transformed between an active transport mode and a stationary mode. In the active transport mode, the components can be within the housing, allowing for patient mobility while attached to the system.
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10.发明授权公开(公告)号：US08641655B2
公开(公告)日：2014-02-04
申请号：US12977931
申请日：2010-12-23
Applicant: Edmond Rambod , Victor Gura
Inventor： Edmond Rambod , Victor Gura
CPC classification number: A61M1/1006 , A61M1/0096 , A61M1/1005 , A61M1/1039 , A61M1/1086 , A61M1/16 , A61M1/1601 , A61M1/1617 , A61M1/1649 , A61M1/1696 , A61M1/34 , A61M1/3403 , A61M1/3607 , A61M1/3639 , A61M1/3663 , A61M2202/0498 , A61M2205/15 , A61M2205/18 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3344 , A61M2205/3382 , A61M2205/50 , A61M2205/8206 , A61M2209/082 , A61M2209/088 , B01D61/32 , B01D2311/14
Abstract: A continuous renal replacement therapy (CRRT) device is provided that weighs between 2 and 10 pounds. The CRRT device can be portable, mobile or completely worn on the person of the patient. Blood and dialysate are each pumped in a pulsed or pulsatile manner through a dialyzer such that a significant portion of the peak pulse of the blood flow coincides with a significant portion of a low pulse portion of the dialysate flow. An differential pressure between a dialysate inlet of the dialyzer and the blood inlet of the dialyzer periodically changes from a high differential pressure of between 70 and 120 mmHg for a first time period and a low differential pressure of between −10 and 10 mmHg for a first time period and a low differential pressure of between −10 and 10 mmHg for a second time period. The frequency of the high and low differential pressure cycle is between about 0.5 and 4 Hz.
Abstract translation: 提供重量在2至10磅之间的连续肾脏替代疗法（CRRT）装置。 CRRT设备可以是便携式的，移动的或完全佩戴在患者身上。 血液和透析液各自以脉冲或脉动方式通过透析器泵送，使得血流的峰值脉冲的相当大部分与透析液流的低脉冲部分的重要部分重合。 透析器的透析液入口与透析器的血液入口之间的压差在第一时间周期性地从70和120mmHg的高压差和-10和10mmHg之间的低压差第一次 时间段和-10和10mmHg之间的低压差第二时间段。 高低压差循环的频率在约0.5Hz和4Hz之间。
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