Method for filling dual-chamber systems in pre-sterilizable carrier systems
    2.
    发明授权
    Method for filling dual-chamber systems in pre-sterilizable carrier systems 失效
    在预消毒的载体系统中填充双室系统的方法

    公开(公告)号:US08763350B2

    公开(公告)日:2014-07-01

    申请号:US12999039

    申请日:2009-06-16

    CPC classification number: B65B3/003 A61J1/2093 A61M5/284 B65B7/2821 B65B55/00

    Abstract: A method for filling dual-chamber systems (3) in pre-sterilizable carrier systems (1) is proposed, which comprises the following steps: provision of at least one washed, siliconized and sterilized dual-chamber system (3) with respectively one separating element separating the two chambers (5, 5′) from one another in a magazine (9), which accommodates the at least one dual-chamber system (3), wherein the magazine (9) is arranged in a container (11) sealed with a closure element (13); feeding the container (11) into a clean room; opening the container (11) and filling a first chamber (5) of the at least one dual-chamber system (3); closing the first chamber (5) with a gas-permeable closure element (19); freeze drying the solution (L1) contained in the first chamber (5); closing the first chamber (5) with a closure element (19); filling a second chamber (5′) of the at least one dual-chamber system (3); closing the second chamber (5′); discharge from the clean room.

    Abstract translation: 提出了一种在预消毒的载体系统(1)中填充双室系统(3)的方法,其包括以下步骤:至少提供一个经洗涤,硅化和灭菌的双室系统(3),分别具有一个分离 所述两个腔室(5,5')在容纳所述至少一个双室系统(3)的盒(9)中彼此分离,其中所述盒(9)布置在密封的容器(11)中 具有闭合元件(13); 将容器(11)送入洁净室; 打开所述容器(11)并填充所述至少一个双室系统(3)的第一室(5); 用气体可透过的封闭元件(19)封闭所述第一腔室(5); 冷冻干燥包含在第一室(5)中的溶液(L1); 用闭合元件(19)封闭第一腔室(5); 填充所述至少一个双室系统(3)的第二室(5'); 关闭第二腔室(5'); 从洁净室排出。

    Method for filling dual-chamber systems in pre-sterilizable carrier systems and pre-sterilizable carrier system
    3.
    发明授权
    Method for filling dual-chamber systems in pre-sterilizable carrier systems and pre-sterilizable carrier system 有权
    在预消毒的载体系统和预消毒的载体系统中填充双室系统的方法

    公开(公告)号:US08677723B2

    公开(公告)日:2014-03-25

    申请号:US12997218

    申请日:2009-06-16

    Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

    Abstract translation: 用于在预消毒的载体系统中填充双室系统的方法包括在盒中提供至少一个洗涤的,硅化的和灭菌的双室系统。 双室系统包括将两个室彼此分开的各自的分离元件。 该杂志容纳至少一个双室系统,并且布置在用闭合元件密封的容器中。 该方法还包括将容器引入洁净室; 打开容器并填充至少一个双室系统的第一室; 并关闭第一个房间。 该方法还包括填充至少一个双室系统的第二室; 关闭第二个房间; 并从洁净室中取出系统。

    METHOD FOR FILLING DUAL-CHAMBER SYSTEMS IN PRE-STERILIZABLE CARRIER SYSTEMS AND PRE-STERILIZABLE CARRIER SYSTEM
    4.
    发明申请
    METHOD FOR FILLING DUAL-CHAMBER SYSTEMS IN PRE-STERILIZABLE CARRIER SYSTEMS AND PRE-STERILIZABLE CARRIER SYSTEM 失效
    在不可消毒的载体系统和预先无菌载体系统中填充双室系统的方法

    公开(公告)号:US20110094189A1

    公开(公告)日:2011-04-28

    申请号:US12999039

    申请日:2009-06-16

    CPC classification number: B65B3/003 A61J1/2093 A61M5/284 B65B7/2821 B65B55/00

    Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system with respectively one separating element separating the two chambers from one another in a magazine, which accommodates the at least one dual-chamber system. The magazine is arranged in a container sealed with a closure element. The method additionally includes feeding the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; closing the first chamber with a gas-permeable closure element; and freeze drying the solution contained in the first chamber. The method further includes closing the first chamber with a closure element; filling a second chamber of the at least one dual-chamber system; closing the second chamber; and discharging the container from the clean room.

    Abstract translation: 一种用于在预消毒的载体系统中填充双室系统的方法包括提供至少一个经洗涤的,硅化的和灭菌的双室系统,分别具有一个分离元件,其将两个室彼此分离在盒中,所述盒容纳至少一个 双室系统。 该杂志被布置在用闭合元件密封的容器中。 该方法还包括将容器进料到洁净室中; 打开容器并填充至少一个双室系统的第一室; 用气体可渗透的封闭元件封闭第一腔室; 并冷冻干燥包含在第一室中的溶液。 该方法还包括用闭合元件关闭第一腔室; 填充所述至少一个双室系统的第二室; 关闭第二个房间; 并从洁净室排出容器。

    Syringe cylinder
    5.
    发明授权
    Syringe cylinder 有权
    注射筒

    公开(公告)号:US08092425B2

    公开(公告)日:2012-01-10

    申请号:US12226465

    申请日:2007-04-19

    CPC classification number: A61M5/5086 A61M2005/3125

    Abstract: A syringe cylinder comprising an interior space, having a stopper that can be displaced in the interior space and delimits an active ingredient space, is proposed. The syringe cylinder is characterized by an indicator device biuniquely indicating a longitudinal movement of the stopper occurring in one direction.

    Abstract translation: 一种注射器筒体,其包括具有可在内部空间中移位并限定活性成分空间的塞子的内部空间。 注射器筒的特征在于指示器装置双重地指示塞子沿一个方向发生的纵向移动。

    Syringe
    6.
    发明申请
    Syringe 有权
    注射器

    公开(公告)号:US20090227957A1

    公开(公告)日:2009-09-10

    申请号:US11990314

    申请日:2006-08-10

    Inventor: Benjamin Böbst

    CPC classification number: A61M5/5013 A61M5/31505 A61M5/502 A61M2005/3139

    Abstract: A syringe includes a syringe cylinder, a sealing plug movably disposed within the syringe cylinder, and with a plunger cooperating with the sealing plug. A safety device prevents a sliding back of the sealing plug within the syringe cylinder in any position the sealing plug assumes within the syringe cylinder. The safety device has a locking element which engages at the plunger in any position the plunger assumes within the syringe cylinder. The locking element is attached to a retaining fixture and protrudes from the retaining fixture same such that an attachment point of the locking element is closer to the sealing plug at the retaining fixture than the free end of the locking element opposite of the attachment point.

    Abstract translation: 注射器包括注射器筒,可移动地设置在注射器筒内的密封塞,以及与密封塞配合的柱塞。 安全装置防止密封塞在注射器筒内的任何位置滑动注射器筒内的密封塞。 安全装置具有锁定元件,其在柱塞处于柱塞在注射器筒内呈现的任何位置处接合。 锁定元件附接到保持夹具并且从保持夹具相同地突出,使得锁定元件的附接点比保持夹具处的密封塞更靠近与附接点相对的锁定元件的自由端。

    METHOD FOR FILLING DUAL-CHAMBER SYSTEMS IN PRE-STERILIZABLE CARRIER SYSTEMS AND PRE-STERILIZABLE CARRIER SYSTEM
    8.
    发明申请
    METHOD FOR FILLING DUAL-CHAMBER SYSTEMS IN PRE-STERILIZABLE CARRIER SYSTEMS AND PRE-STERILIZABLE CARRIER SYSTEM 有权
    在不可消毒的载体系统和预先无菌载体系统中填充双室系统的方法

    公开(公告)号:US20110094188A1

    公开(公告)日:2011-04-28

    申请号:US12997218

    申请日:2009-06-16

    Abstract: A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

    Abstract translation: 用于在预消毒的载体系统中填充双室系统的方法包括在盒中提供至少一个洗涤的,硅化的和灭菌的双室系统。 双室系统包括将两个室彼此分开的各自的分离元件。 该杂志容纳至少一个双室系统,并且布置在用闭合元件密封的容器中。 该方法还包括将容器引入洁净室; 打开容器并填充至少一个双室系统的第一室; 并关闭第一个房间。 该方法还包括填充至少一个双室系统的第二室; 关闭第二个房间; 并从洁净室中取出系统。

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