公开(公告)号：US20190172196A1

公开(公告)日：2019-06-06

申请号：US16000385

申请日：2018-06-05

Applicant: Berkeley Lights, Inc.

Inventor： Fenglei Du ,  Paul M. Lundquist ,  John A. Tenney ,  Troy A. Lionberger

IPC: G06T7/00 ,  G01N21/64 ,  G01N15/14 ,  G06T5/50 ,  G01N27/453

CPC classification number: G06T7/0012 ,  B01L3/502761 ,  G01N15/1434 ,  G01N15/1463 ,  G01N15/1475 ,  G01N15/1484 ,  G01N21/6456 ,  G01N27/453 ,  G01N2015/0038 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1445 ,  G01N2015/1486 ,  G01N2015/1493 ,  G01N2015/1497 ,  G01N2021/056 ,  G01N2021/1765 ,  G01N2201/0635 ,  G01N2201/127 ,  G06T5/50 ,  G06T2207/30024 ,  G06T2207/30101

Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.

公开(公告)号：US09996920B2

公开(公告)日：2018-06-12

申请号：US14963230

申请日：2015-12-08

Applicant: Berkeley Lights, Inc.

Inventor： Fenglei Du ,  Paul M. Lundquist ,  John A. Tenney ,  Troy A. Lionberger

IPC: G06T7/00 ,  G01N15/14 ,  G06T5/50 ,  G01N27/453 ,  G01N21/64 ,  G01N15/00 ,  G01N15/10 ,  G01N21/05 ,  G01N21/17 ,  B01L3/00

CPC classification number: G06T7/0012 ,  B01L3/502761 ,  G01N15/1434 ,  G01N15/1463 ,  G01N15/1475 ,  G01N15/1484 ,  G01N21/6456 ,  G01N27/453 ,  G01N2015/0038 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1445 ,  G01N2015/1486 ,  G01N2015/1493 ,  G01N2015/1497 ,  G01N2021/056 ,  G01N2021/1765 ,  G01N2201/0635 ,  G01N2201/127 ,  G06T5/50 ,  G06T2207/30024 ,  G06T2207/30101

Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.

公开(公告)号：US20160160259A1

公开(公告)日：2016-06-09

申请号：US14964025

申请日：2015-12-09

Applicant: Berkeley Lights, Inc.

Inventor： Fenglei Du

IPC: C12Q1/02 ,  G01N33/543 ,  G01N35/00 ,  G01N21/84

CPC classification number: G01N35/00 ,  B01L3/502792 ,  B01L7/00 ,  B01L2200/0668 ,  B01L2200/147 ,  B01L2200/148 ,  B01L2300/024 ,  B01L2300/0883 ,  B01L2300/1822 ,  B01L2400/0415 ,  B01L2400/0427 ,  B01L2400/0472 ,  G01N21/6458 ,  G01N21/75 ,  G01N21/8483 ,  G01N2021/752 ,  G01N2021/755 ,  G01N2021/757 ,  G01N2201/0635

Abstract: Methods are provided for the automated detection of assay-positive assay areas in a microfluidic device. When assays are performed in a microfluidic device, the configuration of the microfluidic circuit and its constituent circuit elements can determine where the reagents/analytes used in the assay can be located within the microfluidic circuit. Methods are provided for automatic identification of the size and shape of the assay areas based on a number of parameters which may include type of assay involved, shape and dimensions of microfluidic circuit elements, velocity and physical characteristics of the fluidic medium within the microfluidic circuit, physical/chemical properties of the analytes/reagents, and/or the number of cells being assayed.

Abstract translation: 提供了用于在微流体装置中自动检测测定阳性测定区域的方法。 当在微流体装置中进行测定时，微流体电路及其组成电路元件的配置可以确定测定中使用的试剂/分析物可以位于微流体电路内的位置。 提供了用于基于可包括所涉及的测定类型，微流体电路元件的形状和尺寸，微流体电路内的流体介质的速度和物理特性的多个参数自动识别测定区域的尺寸和形状的方法， 分析物/试剂的物理/化学性质，和/或被测定的细胞数量。

公开(公告)号：US20210090252A1

公开(公告)日：2021-03-25

申请号：US17062907

申请日：2020-10-05

Applicant: Berkeley Lights, Inc.

Inventor： Fenglei Du ,  Paul M. Lundquist ,  John A. Tenney ,  Troy A. Lionberger

IPC: G06T7/00 ,  G01N15/14 ,  G01N21/64 ,  G01N27/453 ,  G06T5/50

Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.

公开(公告)号：US10578630B2

公开(公告)日：2020-03-03

申请号：US14964025

申请日：2015-12-09

Applicant: Berkeley Lights, Inc.

Inventor： Fenglei Du

IPC: G01N35/00 ,  G01N21/84 ,  G01N21/64 ,  G01N21/75 ,  B01L3/00 ,  B01L7/00

Abstract: Methods are provided for the automated detection of assay-positive assay areas in a microfluidic device. When assays are performed in a microfluidic device, the configuration of the microfluidic circuit and its constituent circuit elements can determine where the reagents/analytes used in the assay can be located within the microfluidic circuit. Methods are provided for automatic identification of the size and shape of the assay areas based on a number of parameters which may include type of assay involved, shape and dimensions of microfluidic circuit elements, velocity and physical characteristics of the fluidic medium within the microfluidic circuit, physical/chemical properties of the analytes/reagents, and/or the number of cells being assayed.

公开(公告)号：US10832404B2

公开(公告)日：2020-11-10

申请号：US16000385

申请日：2018-06-05

Applicant: Berkeley Lights, Inc.

Inventor： Fenglei Du ,  Paul M. Lundquist ,  John A. Tenney ,  Troy A. Lionberger

IPC: G01L3/00 ,  G01N15/00 ,  G01N15/14 ,  G01N21/05 ,  G01N21/17 ,  G01N21/64 ,  G01N27/453 ,  G06T5/50 ,  G06T7/00 ,  G01N15/10 ,  B01L3/00

Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.

公开(公告)号：US20160171686A1

公开(公告)日：2016-06-16

申请号：US14963230

申请日：2015-12-08

Applicant: Berkeley Lights, Inc.

Inventor： Fenglei Du ,  Paul M. Lundquist ,  John A. Tenney ,  Troy A. Lionberger

IPC: G06T7/00 ,  G01N27/453 ,  G06T5/50

CPC classification number: G06T7/0012 ,  B01L3/502761 ,  G01N15/1434 ,  G01N15/1463 ,  G01N15/1475 ,  G01N15/1484 ,  G01N21/6456 ,  G01N27/453 ,  G01N2015/0038 ,  G01N2015/0065 ,  G01N2015/1006 ,  G01N2015/1445 ,  G01N2015/1486 ,  G01N2015/1493 ,  G01N2015/1497 ,  G01N2021/056 ,  G01N2021/1765 ,  G01N2201/0635 ,  G01N2201/127 ,  G06T5/50 ,  G06T2207/30024 ,  G06T2207/30101

Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.

Abstract translation: 提供了用于在微流体装置中自动检测微物体的方法。 此外，提供了用于在微流体装置中重新定位微物体的方法。 此外，提供了用于分离微流体装置的空间区域中的微物体的方法。