Multi-spectral filter profiling and quality control for flow cytometry

    公开(公告)号:US10180385B2

    公开(公告)日:2019-01-15

    申请号:US15234852

    申请日:2016-08-11

    Abstract: Disclosed is a system and method for characterizing optical filters in a flow cytometer and optionally checking the operation of detectors in the flow cytometer. In some embodiments, the system may utilize an LED board having an opening through which the fluorescence and side scatter beams, rays, or images pass and light emitting diodes around the opening that emit light having different spectral profiles. The different spectral profiles allow the system to identify the optical filters that are placed in the flow cytometer, to verify detector operation, to assist in instrumentation troubleshooting, and to provide a quantitative reference for detector comparison.

    MULTI-SPECTRAL FILTER PROFILING AND QUALITY CONTROL FOR FLOW CYTOMETRY
    5.
    发明申请
    MULTI-SPECTRAL FILTER PROFILING AND QUALITY CONTROL FOR FLOW CYTOMETRY 审中-公开
    用于流动细胞计数的多光谱过滤器分布和质量控制

    公开(公告)号:US20170045436A1

    公开(公告)日:2017-02-16

    申请号:US15234852

    申请日:2016-08-11

    Abstract: Disclosed is a system and method for characterizing optical filters in a flow cytometer and optionally checking the operation of detectors in the flow cytometer. In some embodiments, the system may utilize an LED board having an opening through which the fluorescence and side scatter beams, rays, or images pass and light emitting diodes around the opening that emit light having different spectral profiles. The different spectral profiles allow the system to identify the optical filters that are placed in the flow cytometer, to verify detector operation, to assist in instrumentation troubleshooting, and to provide a quantitative reference for detector comparison.

    Abstract translation: 公开了用于表征流式细胞仪中的滤光器并可选地检查流式细胞仪中的检测器的操作的系统和方法。 在一些实施例中,系统可以利用具有开口的LED板,荧光和侧面散射光束,光线或图像通过该开口,并且围绕开口的发光二极管发射具有不同光谱轮廓的光。 不同的谱分布允许系统识别放置在流式细胞仪中的光学滤波器,以验证检测器操作,以帮助仪器故障排除,并提供用于检测器比较的定量参考。

    Multi-spectral filter profiling and quality control for flow cytometry

    公开(公告)号:US10429291B2

    公开(公告)日:2019-10-01

    申请号:US16247424

    申请日:2019-01-14

    Abstract: Disclosed is a system and method for characterizing optical filters in a flow cytometer and optionally checking the operation of detectors in the flow cytometer. In some embodiments, the system may utilize an LED board having an opening through which the fluorescence and side scatter beams, rays, or images pass and light emitting diodes around the opening that emit light having different spectral profiles. The different spectral profiles allow the system to identify the optical filters that are placed in the flow cytometer, to verify detector operation, to assist in instrumentation troubleshooting, and to provide a quantitative reference for detector comparison.

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