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1.发明申请公开(公告)号：US20220395690A1
公开(公告)日：2022-12-15
申请号：US17838778
申请日：2022-06-13
摘要： A method for estimating neural activation arising from stimulation by a stimulation system includes identifying different neural elements stimulated by the stimulation; obtaining a neural response signal resulting from the stimulation by the stimulation system; and decomposing the neural response signal to estimate neural activation of each of the different neural elements.
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2.发明申请公开(公告)号：US20210023374A1
公开(公告)日：2021-01-28
申请号：US16938745
申请日：2020-07-24
摘要： Methods and systems for making adjustments to electrical stimulation based on patient-specific factors can includes the following instructions or actions: receiving information regarding at least one of i) electrical response of patient tissue, ii) patient response to stimulation, or iii) an arrangement of the implanted lead or the electrodes of the implanted lead with respect to patient anatomy; and calculating an electrode weight for each of a plurality of the electrodes of the implanted lead based on the received information.
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公开(公告)号：US20230413161A1
公开(公告)日：2023-12-21
申请号：US18195172
申请日：2023-05-09
CPC分类号： H04W48/10 , H04L5/0048 , H04W48/16
摘要： A system may include a first device and a second device. The first device may be configured to send advertising packets with a request to communicate with the second device, and the second device may be configured to discover the first device and initiate a wireless communication session with the first device using the advertising packets. The first device may be configured to send advertising packets and send a request to communicate with the second device, and the second device may be configured to discover the first device and initiate a wireless communication session with the first device using the advertising packets.
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公开(公告)号：US20220392627A1
公开(公告)日：2022-12-08
申请号：US17833538
申请日：2022-06-06
IPC分类号： G16H40/63
摘要： A system may include a stimulator, sensing circuitry and a controller. The stimulator may be configured to deliver an electrical therapy using at least one electrode by delivering an electrical waveform according to waveform parameters. The sensing circuitry may be configured to sense electrical potentials. A controller may be configured to detect at least one feature in the sensed electrical potentials, provide closed-loop control of the stimulator using a control algorithm and the detected at least one feature as an input into the control algorithm, determine whether the detected at least one feature is anomalous with respect to the feature data used to determine the one or more relationships, and perform remedial action when it is determined that the at least one feature is anomalous with respect to the feature data.
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公开(公告)号：US20240058610A1
公开(公告)日：2024-02-22
申请号：US18230941
申请日：2023-08-07
IPC分类号： A61N1/36
CPC分类号： A61N1/36139
摘要： Systems and methods for closed-loop control of electrostimulation based on signal features derived from evoked neural activities are disclosed. A system comprises an electrostimulator to deliver a stimulation therapy, a sensing circuit to sense an evoked response induced by the stimulation therapy, and a controller circuit to identify, from a plurality of candidate signal features, a target signal feature that satisfies a performance criterion for distinguishing a first stimulation effect according to a first stimulation setting from a second stimulation effect according to a different second stimulation setting. The target signal feature can be identified based on evaluations of a discrimination metric for each of the candidate signal features. The controller circuit can determine a value of the target signal feature from the sensed evoked response, and control the electrostimulator to adjust the stimulation therapy based on the value of the target signal feature.
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公开(公告)号：US20230181906A1
公开(公告)日：2023-06-15
申请号：US18075868
申请日：2022-12-06
CPC分类号： A61N1/36132 , A61N1/025 , A61N1/36139
摘要： Electrical stimulation systems and methods for operation of the electrical stimulation system are described. The method includes directing electrical stimulation through the electrodes of the lead and monitoring movements of a hand positioned over an implantation site of an implantable control module of the electrical stimulation system using an accelerometer coupled to a processor of the implantable control module. Another method includes detecting, by a sensor, a plurality of taps of a body region of a patient over an implantation site of the implantable control module, identifying, by the processor of the implantable control module, an indicator, trigger, or marker based on the detected tapping, and performing an activity corresponding to the identified indicator, trigger, or marker.
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公开(公告)号：US20230114613A1
公开(公告)日：2023-04-13
申请号：US17950888
申请日：2022-09-22
发明人： G. Karl Steinke , Raul Enrique Serrano Carmona , Andrew James Haddock , Mahsa Malekmohammadi , Rosana Esteller
摘要： An example of a neurostimulation system may include a stimulation output circuit to deliver neurostimulation to evoke responses from a patient using an evoking configuration, a sensing input circuit to sense one or more signals including the evoked responses using a recording configuration, and a control circuit. The control circuit may be configured to control the delivery of the neurostimulation using stimulation parameters including the evoking configuration, to control the sensing of the evoked responses using sensing parameters including the recording configuration, and to determine an evoking-recording parameter set by evaluating a sequence of evoking-recording parameter sets. The evoking-recording parameter set may include a set of the stimulation parameters suitable for controlling the stimulation output circuit to deliver the neurostimulation to evoke a target response and a set of the sensing parameters suitable for controlling the sensing input circuit to record the evoked target response.
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公开(公告)号：US20240285950A1
公开(公告)日：2024-08-29
申请号：US18440468
申请日：2024-02-13
发明人： Tianhe Zhang , Andrew James Haddock
CPC分类号： A61N1/36132 , A61N1/36125 , G16H10/20 , G16H40/67
摘要： An implantable stimulator can control delivery of the neurostimulation to a patient according to a stimulation configuration and adjust the stimulation configuration by using a closed-loop control algorithm. In an example, the system may include a remote controller (RC) configured for use by the patient. The RC may transmit stimulator adjustment information to the implantable stimulator. The stimulator adjustment information may include direct control adjustment information for adjusting the stimulation configuration and adaptation adjustment information for adjusting the closed-loop control algorithm. The RC may generate the stimulator adjustment information based on patient adjustment instructions. The RC includes a user interface configured to receive a patient input and to determine the patient adjustment instructions by interpreting the patient input according to an RC configuration that is programmable for modifying capabilities of the RC in adjusting the stimulation configuration and adjusting the closed-loop control algorithm.
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9.发明授权公开(公告)号：US12053632B2
公开(公告)日：2024-08-06
申请号：US16938745
申请日：2020-07-24
CPC分类号： A61N1/36062 , A61B5/24 , A61B5/316 , A61N1/0551 , A61N1/36132 , A61N1/36139
摘要： Methods and systems for making adjustments to electrical stimulation based on patient-specific factors can includes the following instructions or actions: receiving information regarding at least one of i) electrical response of patient tissue, ii) patient response to stimulation, or iii) an arrangement of the implanted lead or the electrodes of the implanted lead with respect to patient anatomy; and calculating an electrode weight for each of a plurality of the electrodes of the implanted lead based on the received information.
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公开(公告)号：US20230248977A1
公开(公告)日：2023-08-10
申请号：US18107341
申请日：2023-02-08
发明人： Rosana Esteller , Andrew James Haddock , Mahsa Malekmohammadi , Tianhe Zhang , Venugopal Allavatam
CPC分类号： A61N1/36139 , A61B5/388 , A61N1/3614 , A61B5/1101
摘要： This document discusses a computer-implemented method of calibration of an implantable neurostimulation device. The method includes sensing one or more symptoms of a neurological condition of a subject using a sensor external to the neurostimulation device; delivering neurostimulation to the subject using the neurostimulation device and adjusting neurostimulation parameters based on the sensed symptom; sensing one or more neural response signals resulting from the neurostimulation using a sensor of the neurostimulation device; correlating the sensed symptom with the one or more sensed neural response signals; determining a target neural response using the correlating; and recurrently adjusting the neurostimulation parameters according to a comparison of subsequently sensed neural response signals to the target neural response signal.
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