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公开(公告)号:US10751293B2
公开(公告)日:2020-08-25
申请号:US15757561
申请日:2016-09-06
Applicant: CASE WESTERN RESERVE UNIVERSITY
Inventor: Eric Baer , Gary E. Wnek , Mohammad Mofidfar , Jia Wang
IPC: A61K9/70 , B29C48/08 , B29C48/21 , B29C48/00 , B29C48/18 , A61L27/54 , A61L27/48 , A61K8/02 , A61K31/4164 , A61K47/34 , A61L27/18 , A61L27/26 , A61L27/58 , A61Q19/00 , B32B27/08 , B32B27/20 , B32B27/28 , B32B27/36 , D01D5/08 , D01D5/253 , D01F1/10 , D01F6/62 , B29K71/00 , B29K105/00 , B29L31/00
Abstract: A multilayered polymer composite film includes a water-soluble polymer matrix and a plurality of fibers embedded within the water soluble polymer matrix. The fibers include a water insoluble polymer material and at least one of a non-polymeric hydrophobic therapeutic agent or a non-polymeric hydrophobic cosmetic agent incorporated in the water insoluble polymer material. The fibers have a rectangular cross-section, and extend the entire length of the multilayered polymer composite film.
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2.
公开(公告)号:US20180133950A1
公开(公告)日:2018-05-17
申请号:US15814997
申请日:2017-11-16
Applicant: CASE WESTERN RESERVE UNIVERSITY
Inventor: Umit Levent Erol , Mark Weidenbecher , Ozan Akkus , Mohammad Mofidfar
CPC classification number: B29C53/60 , A61F2/04 , A61L27/12 , A61L27/18 , A61L27/56 , A61L29/06 , A61L29/16 , A61L31/06 , A61L31/16 , B29C41/02 , B29C41/085 , B29L2023/007 , B29L2031/7532 , B29L2031/7542 , B29L2031/7546 , C08L67/04
Abstract: A device suitable for constructing hollow cylindrical structures, particularly useful as medical devices. The devices are versatile in nature and can fabricate hollow cylindrical structures having single or multiple layers of one or more different materials, including biomaterials. Methods for utilizing the devices and fabricating hollow cylindrical structures are also disclosed. Fabricated hollow cylindrical structures are described herein. including embodiments incorporating a biomaterial that facilitates cell attachment and tissue integration.
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