公开(公告)号：US20190017195A1

公开(公告)日：2019-01-17

申请号：US16134581

申请日：2018-09-18

Applicant: Case Western Reserve University

Inventor： Eric Baer ,  Jia Wang ,  Deepak Langhe

IPC: D01D5/42 ,  D01F6/66 ,  B32B27/36 ,  B32B27/34 ,  B32B27/30 ,  B32B27/20 ,  D02G3/22 ,  B29C47/14 ,  B29C47/02 ,  D01F8/00 ,  D01D5/253 ,  B32B27/08 ,  B29C47/06 ,  B32B5/12

Abstract: A multilayered polymer composite film includes a first polymer material forming a polymer matrix and a second polymer material coextruded with the first polymer material. The second polymer material forms a plurality of fibers embedded within the polymer matrix. The fibers have a rectangular cross-section.

公开(公告)号：US10010646B2

公开(公告)日：2018-07-03

申请号：US15118030

申请日：2015-02-10

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： Jonathan K Pokorski ,  Eric Baer ,  Kim Sieun ,  Jia Wang

IPC: A61L15/22 ,  A61L15/26 ,  A61F2/02 ,  A61L27/60 ,  A61L15/44

CPC classification number: A61L15/26 ,  A61F2/02 ,  A61L15/44 ,  A61L27/60 ,  A61L2400/12

Abstract: A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers.

公开(公告)号：US20170056544A1

公开(公告)日：2017-03-02

申请号：US15118030

申请日：2015-02-10

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： Jonathan K Pokorski ,  Eric Baer ,  Kim Sieun ,  Jia Wang

IPC: A61L15/26 ,  A61L15/44 ,  A61F2/02

CPC classification number: A61L15/26 ,  A61F2/02 ,  A61L15/44 ,  A61L27/60 ,  A61L2400/12

Abstract: A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers.

Abstract translation: 聚合物纳米纤维支架包括多个熔融挤出的纳米纤维，其被化学修饰以将表面官能度附加到纳米纤维上。

公开(公告)号：US10576181B2

公开(公告)日：2020-03-03

申请号：US16026228

申请日：2018-07-03

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： Jonathan K Pokorski ,  Eric Baer ,  Sieun Kim ,  Jia Wang

IPC: A61F2/00 ,  A61K47/00 ,  A61L15/26 ,  A61L27/60 ,  A61L15/44 ,  A61F2/02

Abstract: A polymer nanofiber scaffold includes a plurality of melt extruded nanofibers that are chemically modified to append surface functionality to the nanofibers.

公开(公告)号：US20190388815A9

公开(公告)日：2019-12-26

申请号：US15691361

申请日：2017-08-30

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： Eric Baer ,  Arifur Rahman ,  Jia Wang ,  Cong Zhangr

IPC: B01D39/16 ,  B01D69/12 ,  B01D71/34 ,  B01D71/26

Abstract: A filter includes a fibrous substrate having a plurality of coextruded first polymer material fibers and second polymer material fibers. Each of the first and second fibers are separated from each other and have a rectangular cross-section defined in part by an additional encapsulating polymer material that is separated from the first polymer material fibers and second polymer material fibers. The fibrous substrate has a pore size range of between about 0.1 μm to about 0.4 μm.

公开(公告)号：US20180043291A1

公开(公告)日：2018-02-15

申请号：US15691361

申请日：2017-08-30

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： Eric Baer ,  Arifur Rahman ,  Jia Wang ,  Cong Zhangr

IPC: B01D39/16 ,  B01D71/34 ,  B01D71/26 ,  B01D69/12

Abstract: A filter includes a fibrous substrate having a plurality of coextruded first polymer material fibers and second polymer material fibers. Each of the first and second fibers are separated from each other and have a rectangular cross-section defined in part by an additional encapsulating polymer material that is separated from the first polymer material fibers and second polymer material fibers. The fibrous substrate has a pore size range of between about 0.1 μm to about 0.4 μm.

公开(公告)号：US20150251116A1

公开(公告)日：2015-09-10

申请号：US14720020

申请日：2015-05-22

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： Eric Baer ,  Jia Wang

IPC: B01D39/16 ,  B29D99/00 ,  B29C47/06

CPC classification number: B01D39/1623 ,  B01D2239/0233 ,  B01D2239/025 ,  B01D2239/064 ,  B29C48/05 ,  B29C48/21 ,  B29C48/23 ,  B29C48/255 ,  B29C48/49 ,  B29C48/71 ,  B29D99/005 ,  B29D99/0078 ,  B29K2023/10 ,  B29K2077/00 ,  B29L2031/14

Abstract: A filter includes a fibrous substrate having a plurality of coextruded first polymer material fibers and second polymer material fibers. Each of the first and second fibers are separated from each other and have a rectangular cross-section defined in part by an additional encapsulating polymer material that is separated from the first polymer material fibers and second polymer material fibers.

Abstract translation: 过滤器包括具有多个共挤出的第一聚合物材料纤维和第二聚合物材料纤维的纤维基材。 第一和第二纤维中的每一个彼此分离，并且具有由与第一聚合物材料纤维和第二聚合物材料纤维分离的另外的包封聚合物材料部分限定的矩形横截面。

公开(公告)号：US10751293B2

公开(公告)日：2020-08-25

申请号：US15757561

申请日：2016-09-06

Applicant: CASE WESTERN RESERVE UNIVERSITY

Inventor： Eric Baer ,  Gary E. Wnek ,  Mohammad Mofidfar ,  Jia Wang

IPC: A61K9/70 ,  B29C48/08 ,  B29C48/21 ,  B29C48/00 ,  B29C48/18 ,  A61L27/54 ,  A61L27/48 ,  A61K8/02 ,  A61K31/4164 ,  A61K47/34 ,  A61L27/18 ,  A61L27/26 ,  A61L27/58 ,  A61Q19/00 ,  B32B27/08 ,  B32B27/20 ,  B32B27/28 ,  B32B27/36 ,  D01D5/08 ,  D01D5/253 ,  D01F1/10 ,  D01F6/62 ,  B29K71/00 ,  B29K105/00 ,  B29L31/00

Abstract: A multilayered polymer composite film includes a water-soluble polymer matrix and a plurality of fibers embedded within the water soluble polymer matrix. The fibers include a water insoluble polymer material and at least one of a non-polymeric hydrophobic therapeutic agent or a non-polymeric hydrophobic cosmetic agent incorporated in the water insoluble polymer material. The fibers have a rectangular cross-section, and extend the entire length of the multilayered polymer composite film.

公开(公告)号：US10077509B2

公开(公告)日：2018-09-18

申请号：US14394234

申请日：2013-04-15

Applicant: Case Western Reserve University

Inventor： Eric Baer ,  Deepak Langhe ,  Jia Wang

IPC: D01D5/42 ,  D02G3/22 ,  B32B27/08 ,  B32B5/12 ,  D01F6/66 ,  B29C47/06 ,  D01D5/253 ,  D01F8/00 ,  B29C47/02 ,  B29C47/14 ,  B32B27/20 ,  B32B27/30 ,  B32B27/34 ,  B32B27/36

CPC classification number: D01D5/42 ,  B29C48/154 ,  B29C48/18 ,  B29C48/30 ,  B29C48/307 ,  B32B5/12 ,  B32B27/08 ,  B32B27/20 ,  B32B27/302 ,  B32B27/34 ,  B32B27/36 ,  B32B2250/02 ,  B32B2250/03 ,  B32B2250/24 ,  B32B2250/40 ,  B32B2262/02 ,  B32B2262/0276 ,  B32B2307/514 ,  B32B2307/54 ,  B32B2367/00 ,  B32B2371/00 ,  B32B2535/00 ,  D01D5/253 ,  D01D5/423 ,  D01F6/66 ,  D01F8/00 ,  D02G3/22 ,  D10B2331/06 ,  D10B2509/00 ,  Y10T428/24752 ,  Y10T428/2973

Abstract: A multilayered polymer composite film includes a first polymer material forming a polymer matrix and a second polymer material coextruded with the first polymer material. The second polymer material forms a plurality of fibers embedded within the polymer matrix. The fibers have a rectangular cross-section.

公开(公告)号：US11111606B2

公开(公告)日：2021-09-07

申请号：US16134581

申请日：2018-09-18

Applicant: Case Western Reserve University

Inventor： Eric Baer ,  Jia Wang ,  Deepak Langhe

IPC: D01D5/42 ,  B29C48/18 ,  B29C48/154 ,  B29C48/305 ,  B32B27/20 ,  B32B27/30 ,  B32B27/34 ,  B32B27/36 ,  D01D5/253 ,  D01F8/00 ,  B32B27/08 ,  B29C48/08 ,  B32B5/12 ,  D01F6/66 ,  D02G3/22 ,  B29C48/12

Abstract: A multilayered polymer composite film includes a first polymer material forming a polymer matrix and a second polymer material coextruded with the first polymer material. The second polymer material forms a plurality of fibers embedded within the polymer matrix. The fibers have a rectangular cross-section.