公开(公告)号：US20150037850A1

公开(公告)日：2015-02-05

申请号：US14370721

申请日：2013-01-03

Applicant: CJ Cheiljedang Corporation

Inventor： Yong Uk Shin ,  So Young Kim ,  In Kyung Heo ,  Ju Eun Kim ,  Sung Kwang Son ,  Jae Hee Lee ,  Ji Hyun Lee ,  Chang Gyeom Kim

IPC: C12P17/12 ,  C12N15/70

CPC classification number: C12P17/12 ,  C12N9/0022 ,  C12N9/1085 ,  C12N15/52 ,  C12N15/62 ,  C12N15/70 ,  C12Y104/03016 ,  C12Y205/01072 ,  Y02P20/52

Abstract: The present invention relates to a quinolinic acid-producing recombinant microorganism expressing a fusion protein of L-aspartate oxidase and quinolinate synthase linked via a linker, and a method for producing quinolinic acid using the same.

Abstract translation: 本发明涉及表达通过接头连接的L-天冬氨酸氧化酶和喹啉酸合成酶的融合蛋白的喹啉酸生产重组微生物及使用其的喹啉酸的制备方法。

公开(公告)号：US10221434B2

公开(公告)日：2019-03-05

申请号：US15031707

申请日：2014-10-22

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Chang Il Seo ,  So Young Kim ,  Yong Uk Shin ,  Kwang Ho Na ,  Hye Won Um ,  In Kyung Heo

IPC: C12P13/06 ,  C12N9/10

Abstract: The present invention relates to a polypeptide which is resistant to feedback inhibition by methionine and has an activity of homoserine O-succinyltransferase, a microorganism for producing O-succinylhomoserine which expresses the polypeptide, and a method for producing O-succinylhomoserine using the same.

公开(公告)号：US10344287B2

公开(公告)日：2019-07-09

申请号：US15323429

申请日：2015-06-30

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Jin Sook Chang ,  Ju Eun Kim ,  So Young Kim ,  Kwang Ho Na ,  Yong Uk Shin ,  Jae Min Lee ,  Jae Hee Lee ,  In Kyung Heo

IPC: C12N1/20 ,  C12N9/10 ,  C12Q1/68 ,  C12P17/12 ,  C07H21/04 ,  C07H21/02 ,  C07K1/00 ,  C12N15/70 ,  C12N15/09 ,  C12P17/10 ,  C12N9/06 ,  C12N15/52

Abstract: The present invention relates to a recombinant microorganism producing quinolinic acid, more particularly, a microorganism producing quinolinic acid and having attenuated activity or eliminated activity of a protein having a sequence of SEQ ID NO: 1 and a method of producing quinolinic acid by using the recombinant microorganism.

公开(公告)号：US09534240B2

公开(公告)日：2017-01-03

申请号：US14370721

申请日：2013-01-03

Applicant: CJ Cheiljedang Corporation

Inventor： Yong Uk Shin ,  So Young Kim ,  In Kyung Heo ,  Ju Eun Kim ,  Sung Kwang Son ,  Jae Hee Lee ,  Ji Hyun Lee ,  Chang Gyeom Kim

IPC: C12P7/40 ,  C12N1/20 ,  C12P17/12 ,  C12N15/62 ,  C12N9/06 ,  C12N9/10 ,  C12N15/70 ,  C12N15/52

CPC classification number: C12P17/12 ,  C12N9/0022 ,  C12N9/1085 ,  C12N15/52 ,  C12N15/62 ,  C12N15/70 ,  C12Y104/03016 ,  C12Y205/01072 ,  Y02P20/52

Abstract: The present invention relates to a quinolinic acid-producing recombinant microorganism expressing a fusion protein of L-aspartate oxidase and quinolinate synthase linked via a linker, and a method for producing quinolinic acid using the same.

Abstract translation: 本发明涉及表达通过接头连接的L-天冬氨酸氧化酶和喹啉酸合成酶的融合蛋白的喹啉酸生产重组微生物及使用其的喹啉酸的制备方法。

公开(公告)号：US20170016037A1

公开(公告)日：2017-01-19

申请号：US15282416

申请日：2016-09-30

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： So Young Kim ,  Yong Uk Shin ,  In Kyung Heo ,  Hyun Ah Kim ,  Ju Eun Kim ,  Chang Il Seo ,  Sung Kwang Son ,  Sang Mok Lee ,  Sung Hoo Jhon ,  Han Jin Lee ,  Kwang Ho Na ,  Il Chul Kim

IPC: C12P13/12 ,  A23L33/175 ,  A61K47/02 ,  A61K9/08 ,  A61K31/20

CPC classification number: C12P13/12 ,  A23L33/175 ,  A23V2002/00 ,  A61K9/08 ,  A61K31/20 ,  A61K47/02 ,  C07C319/26 ,  C07C323/52

Abstract: The present invention relates to a method for enhancing the solubility of methionine. More particularly, the present invention relates to a method for increasing the solubility of methionine, in which mineral and sulfuric acid are added at an appropriate ratio to enhance the methionine solubility, thereby overcoming the problem of low solubility of methionine in water.

Abstract translation: 本发明涉及提高甲硫氨酸溶解度的方法。 更具体地说，本发明涉及增加甲硫氨酸的溶解度的方法，其中以适当的比例加入矿物和硫酸以提高甲硫氨酸的溶解度，从而克服了蛋氨酸在水中溶解度低的问题。