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公开(公告)号：US12173341B2
公开(公告)日：2024-12-24
申请号：US17423262
申请日：2021-01-21
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Jee Yeon Bae , Byoung Hoon Yoon , Su Yon Kwon , Kyungrim Kim , Ju Eun Kim , Hyo Jeong Byun , Seung Hyun Cho , Nara Kwon , Hyung Joon Kim
Abstract: The present disclosure relates to a microorganism of the genus Corynebacterium having an increased L-amino acid producing ability, containing NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from the genus Lactobacillus. According to the present disclosure, the NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from Lactobacillus delbrueckii subsp. bulgaricus is introduced to increase the reducing power through the activity of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, thereby increasing the L-amino acid producing ability of the strains belonging to the genus Corynebacterium.
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2.发明申请公开(公告)号：US20150037850A1
公开(公告)日：2015-02-05
申请号：US14370721
申请日：2013-01-03
Applicant: CJ Cheiljedang Corporation
Inventor： Yong Uk Shin , So Young Kim , In Kyung Heo , Ju Eun Kim , Sung Kwang Son , Jae Hee Lee , Ji Hyun Lee , Chang Gyeom Kim
CPC classification number: C12P17/12 , C12N9/0022 , C12N9/1085 , C12N15/52 , C12N15/62 , C12N15/70 , C12Y104/03016 , C12Y205/01072 , Y02P20/52
Abstract: The present invention relates to a quinolinic acid-producing recombinant microorganism expressing a fusion protein of L-aspartate oxidase and quinolinate synthase linked via a linker, and a method for producing quinolinic acid using the same.
Abstract translation: 本发明涉及表达通过接头连接的L-天冬氨酸氧化酶和喹啉酸合成酶的融合蛋白的喹啉酸生产重组微生物及使用其的喹啉酸的制备方法。
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Patent Agency Ranking
公开(公告)号：US10344287B2
公开(公告)日：2019-07-09
申请号：US15323429
申请日：2015-06-30
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Jin Sook Chang , Ju Eun Kim , So Young Kim , Kwang Ho Na , Yong Uk Shin , Jae Min Lee , Jae Hee Lee , In Kyung Heo
IPC: C12N1/20 , C12N9/10 , C12Q1/68 , C12P17/12 , C07H21/04 , C07H21/02 , C07K1/00 , C12N15/70 , C12N15/09 , C12P17/10 , C12N9/06 , C12N15/52
Abstract: The present invention relates to a recombinant microorganism producing quinolinic acid, more particularly, a microorganism producing quinolinic acid and having attenuated activity or eliminated activity of a protein having a sequence of SEQ ID NO: 1 and a method of producing quinolinic acid by using the recombinant microorganism.
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4.发明授权公开(公告)号：US09534240B2
公开(公告)日：2017-01-03
申请号：US14370721
申请日：2013-01-03
Applicant: CJ Cheiljedang Corporation
Inventor： Yong Uk Shin , So Young Kim , In Kyung Heo , Ju Eun Kim , Sung Kwang Son , Jae Hee Lee , Ji Hyun Lee , Chang Gyeom Kim
CPC classification number: C12P17/12 , C12N9/0022 , C12N9/1085 , C12N15/52 , C12N15/62 , C12N15/70 , C12Y104/03016 , C12Y205/01072 , Y02P20/52
Abstract: The present invention relates to a quinolinic acid-producing recombinant microorganism expressing a fusion protein of L-aspartate oxidase and quinolinate synthase linked via a linker, and a method for producing quinolinic acid using the same.
Abstract translation: 本发明涉及表达通过接头连接的L-天冬氨酸氧化酶和喹啉酸合成酶的融合蛋白的喹啉酸生产重组微生物及使用其的喹啉酸的制备方法。
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公开(公告)号：US20220348973A1
公开(公告)日：2022-11-03
申请号：US17423262
申请日：2021-01-21
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： Jee Yeon Bae , Byoung Hoon Yoon , Su Yon Kwon , Kyungrim Kim , Ju Eun Kim , Hyo Jeong Byun , Seung Hyun Cho , Nara Kwon , Hyung Joon Kim
Abstract: The present disclosure relates to a microorganism of the genus Corynebacterium having an increased L-amino acid producing ability, containing NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from the genus Lactobacillus. According to the present disclosure, the NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from Lactobacillus delbrueckii subsp. bulgaricus is introduced to increase the reducing power through the activity of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, thereby increasing the L-amino acid producing ability of the strains belonging to the genus Corynebacterium.
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6.发明申请Method for Increasing the Solubility of Methionine by Mineral Addition and Acid Treatment 审中-公开通过矿物添加和酸处理提高甲硫氨酸的溶解度的方法公开(公告)号：US20170016037A1
公开(公告)日：2017-01-19
申请号：US15282416
申请日：2016-09-30
Applicant: CJ CHEILJEDANG CORPORATION
Inventor： So Young Kim , Yong Uk Shin , In Kyung Heo , Hyun Ah Kim , Ju Eun Kim , Chang Il Seo , Sung Kwang Son , Sang Mok Lee , Sung Hoo Jhon , Han Jin Lee , Kwang Ho Na , Il Chul Kim
IPC: C12P13/12 , A23L33/175 , A61K47/02 , A61K9/08 , A61K31/20
CPC classification number: C12P13/12 , A23L33/175 , A23V2002/00 , A61K9/08 , A61K31/20 , A61K47/02 , C07C319/26 , C07C323/52
Abstract: The present invention relates to a method for enhancing the solubility of methionine. More particularly, the present invention relates to a method for increasing the solubility of methionine, in which mineral and sulfuric acid are added at an appropriate ratio to enhance the methionine solubility, thereby overcoming the problem of low solubility of methionine in water.
Abstract translation: 本发明涉及提高甲硫氨酸溶解度的方法。 更具体地说，本发明涉及增加甲硫氨酸的溶解度的方法，其中以适当的比例加入矿物和硫酸以提高甲硫氨酸的溶解度，从而克服了蛋氨酸在水中溶解度低的问题。
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7.发明申请公开(公告)号：US20180163186A1
公开(公告)日：2018-06-14
申请号：US15546467
申请日：2015-12-28
Applicant: CJ Cheiljedang Corporation
Inventor： Jaemin Lee , Ju Eun Kim , Jae Hee Lee , Jin Sook Chang , So Young Kim , Yong Uk Shin
Abstract: The present disclosure relates to a microorganism having producing ability of quinolinic acid and a method for producing quinolinic acid using the microorganism.
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