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公开(公告)号:US20220348973A1
公开(公告)日:2022-11-03
申请号:US17423262
申请日:2021-01-21
Applicant: CJ CHEILJEDANG CORPORATION
Inventor: Jee Yeon Bae , Byoung Hoon Yoon , Su Yon Kwon , Kyungrim Kim , Ju Eun Kim , Hyo Jeong Byun , Seung Hyun Cho , Nara Kwon , Hyung Joon Kim
Abstract: The present disclosure relates to a microorganism of the genus Corynebacterium having an increased L-amino acid producing ability, containing NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from the genus Lactobacillus. According to the present disclosure, the NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from Lactobacillus delbrueckii subsp. bulgaricus is introduced to increase the reducing power through the activity of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, thereby increasing the L-amino acid producing ability of the strains belonging to the genus Corynebacterium.
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公开(公告)号:US12173341B2
公开(公告)日:2024-12-24
申请号:US17423262
申请日:2021-01-21
Applicant: CJ CHEILJEDANG CORPORATION
Inventor: Jee Yeon Bae , Byoung Hoon Yoon , Su Yon Kwon , Kyungrim Kim , Ju Eun Kim , Hyo Jeong Byun , Seung Hyun Cho , Nara Kwon , Hyung Joon Kim
Abstract: The present disclosure relates to a microorganism of the genus Corynebacterium having an increased L-amino acid producing ability, containing NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from the genus Lactobacillus. According to the present disclosure, the NADP-dependent glyceraldehyde-3-phosphate dehydrogenase derived from Lactobacillus delbrueckii subsp. bulgaricus is introduced to increase the reducing power through the activity of NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, thereby increasing the L-amino acid producing ability of the strains belonging to the genus Corynebacterium.
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公开(公告)号:US10982244B2
公开(公告)日:2021-04-20
申请号:US16478286
申请日:2019-04-10
Applicant: CJ CHEILJEDANG CORPORATION
Inventor: Su Yon Kwon , Kwang Woo Lee , Lan Huh , Kyungrim Kim , Mina Baek , Seung-ju Son , Jaemin Lee
Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing homoserine or a homoserine-derived L-amino acid using the same.
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公开(公告)号:US10113191B2
公开(公告)日:2018-10-30
申请号:US15112855
申请日:2015-03-17
Applicant: CJ CHEILJEDANG CORPORATION
Inventor: Eun Sung Koh , Su Yon Kwon , Kwang Ho Lee , Ji Sun Lee , Juno Jang , Keun Cheol Lee , Hyeong Pyo Hong
Abstract: Disclosed are a recombinant microorganism having enhanced L-amino acid productivity, wherein the recombinant microorganism is transformed to have removed or decreased activity of at least one of adenosine deaminase and AMP nucleosidase, and a method of producing an L-amino acid using the recombinant microorganism. The use of the recombinant microorganism may enable the production of the L-amino acid in a highly efficient manner.
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公开(公告)号:US20190024060A1
公开(公告)日:2019-01-24
申请号:US15768497
申请日:2016-10-21
Applicant: CJ Cheiljedang Corporation
Inventor: Su Yon Kwon , Jae Woo Jang , Min Se Kim , Ju Jeong Kim
Abstract: The present application relates to a microorganism of the genus Corynebacterium having L-isoleucine producing ability which comprises a protein having an activity of citramalate synthase, and a method for producing L-isoleucine using the same.
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公开(公告)号:US10053698B2
公开(公告)日:2018-08-21
申请号:US15112992
申请日:2014-04-25
Applicant: CJ Cheiljedang Corporation
Inventor: Hyung Joon Kim , Su Yon Kwon , Eun Sung Koh , Ji Sun Lee , Keun Cheol Lee , Young Bin Hwang , Hyeong Pyo Hong
Abstract: The present invention relates to an E. coli mutant strain having enhanced L-threonine productivity, which is obtained by introducing the permease of Corynebacterium origin, and to method of producing L-threonine using the E. coli mutant strain.
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