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公开(公告)号:US10052045B2
公开(公告)日:2018-08-21
申请号:US14441184
申请日:2012-12-21
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid
CPC classification number: A61B5/08 , A61B5/082 , A61B10/00 , A61B2010/0087 , A61K8/33 , A61K8/35 , A61K8/55 , A61Q11/00 , G01N33/497 , G01N2033/4975 , Y10T436/182
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
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公开(公告)号:US09823236B2
公开(公告)日:2017-11-21
申请号:US14441962
申请日:2012-12-21
Applicant: Colgate-Palmolive Company
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
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公开(公告)号:US20150293075A1
公开(公告)日:2015-10-15
申请号:US14441962
申请日:2012-12-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid , Ariel Haskel
IPC: G01N33/497 , A61K8/33 , A61K8/35 , A61Q11/00 , A61K8/24
CPC classification number: G01N33/497 , A61K8/24 , A61K8/33 , A61K8/35 , A61K8/4913 , A61K8/4973 , A61K2800/591 , A61Q11/00
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from coffee. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a sample of exhaled breath from the cleaned oral cavity to provide a test result representing a amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a sample of exhaled breath from the oral cavity to provide a test result representing an amount of the at least one oral malodor component detected in the exhaled breath.
Abstract translation: 本发明涉及一种用于测试口腔恶臭,特别是咖啡口服恶臭的方法。 本文描述了用于测试口腔护理组合物降低口腔恶臭的功效的方法,该方法包括以下步骤:a)用口腔护理组合物清洁至少一部分口腔; b)从清洁的口腔测试呼出的呼吸样品,以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果; c)将口腔暴露于包含或能够形成至少一种口腔恶臭成分的口腔恶臭物质; 以及d)从口腔测试呼出的呼吸样品,以提供表示在呼出气中检测到的至少一种口腔恶臭成分的量的测试结果。
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公开(公告)号:US11622924B2
公开(公告)日:2023-04-11
申请号:US14905770
申请日:2014-07-16
Applicant: Colgate-Palmolive Company , NIZO FOOD RESEARCH B.V.
Inventor: Ariel Haskel , Jessica Monk , Najma Khan , Kerstin Burseg , Peter De Kok , Ann Stijnman
Abstract: Systems and methods for mixing an oral care formulation base with one or more oral care additives in-situ. In one aspect, the invention can be a method of making an oral care formulation for consumer use, the method comprising: a) providing a first dose of an oral care formulation base to an oral cavity of a test subject; b) dispensing one or more oral care additives to the oral cavity in accordance with a first dispensing regimen during the performance of step a), the one or more oral care additives mixing with the first dose of the oral care formulation base in-situ within the oral cavity of the test subject; c) obtaining feedback regarding effects experienced by the test subject during the performance of step b); and d) creating the oral care formulation for consumer use based, at least in part, on the feedback of step c).
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公开(公告)号:US20150265183A1
公开(公告)日:2015-09-24
申请号:US14441184
申请日:2012-12-21
Applicant: COLGATE-PALMOLIVE COMPANY
Inventor: Zhigang Hao , Deborah A. Peru , Joe Vazquez , Jessica Monk , Harsh M. Trivedi , Paul Joseph Vincenti , Osman Khalid
IPC: A61B5/08 , A61B10/00 , G01N33/497 , A61Q11/00 , A61K8/55
CPC classification number: A61B5/08 , A61B5/082 , A61B10/00 , A61B2010/0087 , A61K8/33 , A61K8/35 , A61K8/55 , A61Q11/00 , G01N33/497 , G01N2033/4975 , Y10T436/182
Abstract: The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
Abstract translation: 本发明涉及一种口服恶臭的检测方法,特别是洋葱和大蒜口服恶臭。 本文描述了用于测试口腔护理组合物降低口腔恶臭的功效的方法,该方法包括以下步骤:a)用口腔护理组合物清洁至少一部分口腔; b)从清洁的口腔测试呼出呼吸的第一样本,以提供表示在呼出气中检测到的第一量的至少一种口腔恶臭成分的第一测试结果; c)将口腔暴露于包含或能够形成至少一种口腔恶臭成分的口腔恶臭物质; 以及d)从所述口腔测试第二呼出呼气样品,以提供第二测试结果,所述第二测试结果代表在所述呼出气体中检测到的所述至少一种口腔恶臭成分的第二量。
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