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公开(公告)号：US09579501B2
公开(公告)日：2017-02-28
申请号：US14014007
申请日：2013-08-29
Applicant: Cardiac Pacemakers, Inc.
Inventor： Allan C. Shuros , Bruce A. Tockman , G. Shantanu Reddy
CPC classification number: A61N1/059 , A61N1/0565 , A61N1/0573 , A61N1/362 , A61N1/372
Abstract: Various embodiments concern implanting a lead to directly stimulate the bundle of His. Various embodiments can include introducing a curve of an outer guide catheter into the right ventricle, extending a curve of an inner guide catheter from a lumen of the outer guide catheter, extending a fixation element on a distal tip of an anchor wire from a lumen the inner guide catheter, and anchoring the anchor wire to target tissue within the right ventricle, the target tissue along the septal wall and proximate the tricuspid valve and the bundle of His. A distal tip of an implantable lead with a lumen can then be advanced over the anchor wire to the target tissue as the anchor wire guides the distal tip of the lead to the target tissue.
Abstract translation: 各种实施例涉及植入铅直接刺激His束。 各种实施例可以包括将外引导导管的曲线引入右心室，将内引导导管的曲线从外引导导管的内腔延伸，将固定丝的远侧末端上的固定元件从内腔延伸 内导向导管，并将锚线锚固在右心室内的靶组织上，沿着隔膜壁的靶组织和靠近三尖瓣和His束。 然后随着锚线将引线的远侧末端引导到目标组织，可以将具有内腔的可植入引线的远侧末端推进到锚定线上到目标组织。
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2.发明申请公开(公告)号：US20140135884A1
公开(公告)日：2014-05-15
申请号：US14157286
申请日：2014-01-16
Applicant: Cardiac Pacemakers, Inc.
Inventor： Bruce A. Tockman , Timothy R. Jackson , Peter J. Wolf , Christopher A. Fuhs
IPC: A61N1/05
CPC classification number: A61N1/05 , A61N1/375 , H01R2201/12
Abstract: A peel-away lead implant tool is described. The peel away lead implant tool is adapted to be disposed over the terminal connector of a lead during an implantation procedure to protect the terminal connector. The peel-away lead implant tool includes a flexible polymer sheath including electrical contacts formed in a contact region of the sheath. The electrical contacts can be either metal foil contacts or conductive polymer contacts and extend from an outer surface to an inner surface of the sheath such that when the testing apparatus is coupled to the lead implant tool, the electrical contacts are pressed into electrical contact with the ring electrodes located on the terminal connector. The lead implant tool also includes various removal means facilitating the easy removal of the implant tool from the terminal connector when the implantation procedure is complete.
Abstract translation: 描述了一个剥离的铅离子植入工具。 剥离引线植入工具适于在植入过程期间设置在引线的端子连接器上以保护端子连接器。 剥离引线植入工具包括柔性聚合物护套，其包括形成在护套的接触区域中的电触点。 电触点可以是金属箔触点或导电聚合物触点，并且从护套的外表面延伸到内表面，使得当测试装置耦合到引线注入工具时，电触点被压入与电接触 位于端子连接器上的环形电极。 引线植入工具还包括各种移除装置，当植入程序完成时便于从终端连接器容易地移除植入物工具。
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公开(公告)号：US20140067036A1
公开(公告)日：2014-03-06
申请号：US14014007
申请日：2013-08-29
Applicant: Cardiac Pacemakers, Inc.
Inventor： Allan C. Shuros , Bruce A. Tockman , G. Shantanu Reddy
IPC: A61N1/05
CPC classification number: A61N1/059 , A61N1/0565 , A61N1/0573 , A61N1/362 , A61N1/372
Abstract: Various embodiments concern implanting a lead to directly stimulate the bundle of His. Various embodiments can include introducing a curve of an outer guide catheter into the right ventricle, extending a curve of an inner guide catheter from a lumen of the outer guide catheter, extending a fixation element on a distal tip of an anchor wire from a lumen the inner guide catheter, and anchoring the anchor wire to target tissue within the right ventricle, the target tissue along the septal wall and proximate the tricuspid valve and the bundle of His. A distal tip of an implantable lead with a lumen can then be advanced over the anchor wire to the target tissue as the anchor wire guides the distal tip of the lead to the target tissue.
Abstract translation: 各种实施例涉及植入铅直接刺激His束。 各种实施例可以包括将外引导导管的曲线引入右心室，将内引导导管的曲线从外引导导管的内腔延伸，将固定丝的远侧末端上的固定元件从内腔延伸 内导向导管，并将锚线锚固在右心室内的靶组织上，沿着隔膜壁的靶组织和靠近三尖瓣和His束。 然后随着锚线将引线的远侧末端引导到目标组织，可以将具有内腔的可植入引线的远侧末端推进到锚定线上到目标组织。
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公开(公告)号：US20140188202A1
公开(公告)日：2014-07-03
申请号：US14141702
申请日：2013-12-27
Applicant: Cardiac Pacemakers, Inc.
Inventor： Paul E. Zarembo , Bruce A. Tockman
IPC: A61N1/05
CPC classification number: A61N1/0556
Abstract: Various embodiments concern wrapping a stimulation cuff around a nerve. The cuff can comprise a main body and at least one electrode. The main body can comprise an inner tab, an outer tab, and an intermediate portion extending between the inner tab and the outer tab, the at least one electrode disposed on the intermediate portion, the main body biased such that the cuff assumes the coiled arrangement. The cuff can be uncoiled by pulling on a first elongate element attached to a first tubular member, the first tubular member encircled within the cuff. The nerve can be engaged with an inner surface of the main body along the intermediate portion while the inner tab is releaseably attached to the first elongate element. The first elongate element can be released to allow the cuff to wrap around the nerve.
Abstract translation: 各种实施例涉及在神经周围包裹刺激袖带。 袖带可以包括主体和至少一个电极。 主体可以包括内部突片，外部突片和在内部突片和外部突出部之间延伸的中间部分，所述至少一个电极设置在中间部分上，主体被偏压使得袖带呈现卷绕的布置 。 通过拉动附接到第一管状构件的第一细长元件可以展开袖带，第一管状构件环绕在袖带内。 神经可以沿着中间部分与主体的内表面接合，而内突片可释放地附接到第一细长元件。 可以释放第一细长元件以允许袖带包裹在神经周围。
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公开(公告)号：US20140039312A1
公开(公告)日：2014-02-06
申请号：US13953904
申请日：2013-07-30
Applicant: Cardiac Pacemakers, Inc.
Inventor： Holly E. Rockweiller , Rodney W. Salo , Bruce A. Tockman , Lewis J. Thomas, III , Aaron R. McCabe , Brian D. Soltis , Darrell L. Rankin , Michael S. Arney , Alex J. Sepulveda
IPC: A61N1/372
CPC classification number: A61N1/372 , A61B5/0422 , A61B5/1107 , A61B8/0883 , A61B8/12 , A61B8/4254 , A61B8/445 , A61B8/485 , A61B8/543 , A61N1/3625 , A61N1/3686 , A61N1/37241
Abstract: Techniques are disclosed for pacing site selection. In one example, a method includes using a sensing element such as an ultrasonic transducer, an optical pressure sensor, a MEMS pressure sensor, a SAW pressure sensor, an accelerometer, a gyroscope, or any other suitable sensing element to sense a measure related to a cardiac strain in a heart resulting from contraction and relaxation of myocardium during a cardiac cycle. Based on the sensed strain, an output may be provided for use by a user of the system to select a segment of the heart for lead placement.
Abstract translation: 公开了用于起搏站点选择的技术。 在一个示例中，一种方法包括使用诸如超声波换能器的感测元件，光学压力传感器，MEMS压力传感器，SAW压力传感器，加速度计，陀螺仪或任何其它合适的感测元件来感测与 在心脏周期期间由于心肌的收缩和松弛引起的心脏心脏应变。 基于感测到的应变，可以提供输出以供系统的用户使用以选择用于引线放置的心脏的片段。
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Patent Agency Ranking
6.发明授权公开(公告)号：US10555726B2
公开(公告)日：2020-02-11
申请号：US14743803
申请日：2015-06-18
Applicant: Cardiac Pacemakers, Inc.
Inventor： Juan Gabriel Hincapie Ordonez , Bruce A. Tockman , Brian Soltis , Lili Liu , Eric F. Hammill
IPC: A61B17/00 , A61N1/05 , A61B34/20 , G01R33/28 , A61B90/00 , A61B5/06 , A61B8/08 , A61B18/00 , A61B17/32
Abstract: Various aspects describe a lead delivery system for percutaneous introduction of a lead to a stimulation site near a neural target, such as the vagus nerve for nerve stimulation. The lead delivery system may include a needle assembly having a needle adapted to cut through tissue and provide initial access into the carotid sheath. The needle may be retracted into the lead delivery system to prevent cutting structures in the carotid sheath. The lead delivery system may also include a dilator assembly having one or more dilators to dilate a path to the stimulation site. The lead delivery system may further comprise a dilator assembly including a retractable needle adapted to cut through tissue. One or more locating elements, alternatively or in addition to one or more imaging elements, may be used on individual components of the lead delivery system for enhanced trackability and locatability within the body.
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公开(公告)号：US20160089183A1
公开(公告)日：2016-03-31
申请号：US14865983
申请日：2015-09-25
Applicant: Cardiac Pacemakers, Inc.
Inventor： Bruce A. Tockman , Brian Soltis , Eric F. Hammill , Lili Liu , Juan Gabriel Hincapie Ordonez
CPC classification number: A61B17/3468 , A61B5/0538 , A61B17/3403 , A61B2017/320056 , A61B2017/3413 , A61N1/0551 , A61N1/36053
Abstract: The disclosure relates to a needle assembly for delivering a lead and methods of use. The needle assembly is configured to cut tissue and reduce the potential for cutting vulnerable bodily structures. The needle assembly includes an outer needle with a blunt tip and an inner needle with a sharp tip. The outer needle may be curved, and the inner needle may be curved. When the inner needle is rotated with respect to the outer needle, the inner needle protracts or retracts with respect to the outer needle. A stopping feature on the needle assembly may be included to resist over-rotation or over-extension. The needle assembly provides an initial path that may be further dilated for delivering a lead, such as a vagus nerve stimulation lead to a target site. The target site may be electrically tested with some embodiments.
Abstract translation: 本公开涉及一种用于传送引线的针组件和使用方法。 针组件被配置为切割组织并减少切割易受伤害的身体结构的可能性。 针组件包括具有钝头的外针和具有尖锐尖端的内针。 外针可以是弯曲的，并且内针可以是弯曲的。 当内针相对于外针旋转时，内针相对于外针延伸或缩回。 可以包括针组件上的止动特征以抵抗过度旋转或过度伸展。 针组件提供了可以进一步扩张以将导联（例如迷走神经刺激引线）输送到靶位点的初始路径。 目标部位可以用一些实施例进行电测试。
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公开(公告)号：US20150190639A1
公开(公告)日：2015-07-09
申请号：US14667240
申请日：2015-03-24
Applicant: Cardiac Pacemakers, Inc.
Inventor： Alok S. Sathaye , M. Jason Brooke , Bruce A. Tockman
CPC classification number: A61N1/3686 , A61N1/056 , A61N1/08 , A61N1/36514 , A61N1/3702 , A61N1/3704 , A61N1/371 , A61N1/37223 , A61N1/37247 , A61N2001/083
Abstract: Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.
Abstract translation: 描述了选择多电极起搏装置的电极组合的方法。 针对多个电极组合中的每一个评估支持与规定治疗一致的心脏功能的电极组合参数。 针对多个电极组合中的每一个评估不支持心脏功能的电极组合参数。 基于参数评估确定电极组合的顺序。 基于顺序选择电极组合，并且使用所选择的电极组合递送治疗。
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公开(公告)号：US08983626B2
公开(公告)日：2015-03-17
申请号：US14141702
申请日：2013-12-27
Applicant: Cardiac Pacemakers, Inc.
Inventor： Paul E. Zarembo , Bruce A. Tockman
IPC: A61N1/05
CPC classification number: A61N1/0556
Abstract: Various embodiments concern wrapping a stimulation cuff around a nerve. The cuff can comprise a main body and at least one electrode. The main body can comprise an inner tab, an outer tab, and an intermediate portion extending between the inner tab and the outer tab, the at least one electrode disposed on the intermediate portion, the main body biased such that the cuff assumes the coiled arrangement. The cuff can be uncoiled by pulling on a first elongate element attached to a first tubular member, the first tubular member encircled within the cuff. The nerve can be engaged with an inner surface of the main body along the intermediate portion while the inner tab is releaseably attached to the first elongate element. The first elongate element can be released to allow the cuff to wrap around the nerve.
Abstract translation: 各种实施例涉及在神经周围包裹刺激袖带。 袖带可以包括主体和至少一个电极。 主体可以包括内部突片，外部突片和在内部突片和外部突出部之间延伸的中间部分，所述至少一个电极设置在中间部分上，主体被偏压使得袖带呈现卷绕的布置 。 通过拉动附接到第一管状构件的第一细长元件可以展开袖带，第一管状构件环绕在袖带内。 神经可以沿着中间部分与主体的内表面接合，而内突片可释放地附接到第一细长元件。 可以释放第一细长元件以允许袖带包裹在神经周围。
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公开(公告)号：US20140194942A1
公开(公告)日：2014-07-10
申请号：US14209364
申请日：2014-03-13
Applicant: Cardiac Pacemakers, Inc.
Inventor： Alok S. Sathaye , M. Jason Brooke , Bruce A. Tockman
IPC: A61N1/37
CPC classification number: A61N1/3686 , A61N1/056 , A61N1/08 , A61N1/36514 , A61N1/3702 , A61N1/3704 , A61N1/371 , A61N1/37223 , A61N1/37247 , A61N2001/083
Abstract: Approaches for selecting an electrode combination of multi-electrode pacing devices are described. Electrode combination parameters that support cardiac function consistent with a prescribed therapy are evaluated for each of a plurality of electrode combinations. Electrode combination parameters that do not support cardiac function are evaluated for each of the plurality of electrode combinations. An order is determined for the electrode combinations based on the parameter evaluations. An electrode combination is selected based on the order, and therapy is delivered using the selected electrode combination.
Abstract translation: 描述了选择多电极起搏装置的电极组合的方法。 针对多个电极组合中的每一个评估支持与规定治疗一致的心脏功能的电极组合参数。 针对多个电极组合中的每一个评估不支持心脏功能的电极组合参数。 基于参数评估确定电极组合的顺序。 基于顺序选择电极组合，并且使用所选择的电极组合递送治疗。
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