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    Paddle leads configured for suture fixation
    3.
    发明授权
    Paddle leads configured for suture fixation 有权
    配置用于缝合线固定的桨形引线

    公开(公告)号：US09572975B2

    公开(公告)日：2017-02-21

    申请号：US14843836

    申请日：2015-09-02

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Andrew L. De Kock ,  Brian Soltis ,  Eric A. Mokelke

    IPC: A61N1/00 ,  A61N1/05 ,  A61N1/36

    CPC classification number: A61N1/0553 ,  A61N1/0558 ,  A61N1/36117

    Abstract: Various embodiments concern an implantable paddle lead. The paddle can be attached to a distal portion of an elongate lead body. The paddle can comprise a main panel and a ridge that peripherally surrounds the main panel. The main panel can comprise a first face and a second face opposite the first face. One or more electrodes can be exposed on the first face but not exposed on the second face. The paddles can be sutured to anatomical structures. The sutures can be threaded through the main panel but not through the ridge. The paddle can be thicker along the ridge than along the main panel.

    Abstract translation: 各种实施例涉及可植入桨叶。 桨可以附接到细长引线体的远端部分。 桨可以包括主面板和外围围绕主面板的脊。 主面板可以包括与第一面相对的第一面和第二面。 一个或多个电极可以暴露在第一面上，但不暴露在第二面上。 桨可以缝合到解剖结构。 缝合线可穿过主面板，但不能穿过脊。 桨叶沿着脊线可以比沿着主面板更厚。

    SYSTEM AND METHOD FOR LOCATING NEURAL TISSUE
    4.
    发明申请
    SYSTEM AND METHOD FOR LOCATING NEURAL TISSUE 有权
    用于定位神经组织的系统和方法

    公开(公告)号：US20150173636A1

    公开(公告)日：2015-06-25

    申请号：US14570347

    申请日：2014-12-15

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Eric A. Mokelke ,  David J. Ternes ,  Allan Charles Shuros ,  Hong Cao

    IPC: A61B5/04 ,  A61B18/12 ,  A61N1/36

    CPC classification number: A61B5/04001 ,  A61B5/0538 ,  A61B5/4893 ,  A61B5/6848 ,  A61B18/1206 ,  A61B18/1492 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/124 ,  A61B2562/046 ,  A61N1/0551 ,  A61N1/36128 ,  A61N1/36139 ,  A61N1/36185

    Abstract: An example of a system comprises a patch of electrodes for placement on tissue containing neural tissue, and a tissue tester configured to measure an electrical characteristic of tissue. The tissue tester may include a test controller and switches. The test controller and the switches may be configured to connect different combinations of the electrodes to create subsets of two or more electrodes to measure the electrical characteristic of tissue using the subsets. The test controller may be configured to measure an electrical characteristic of tissue using the subsets within the set of electrodes placed on the tissue, and compare measurements of the electrical characteristic and identify a neural target for a therapy based on the comparison of the measurements of the electrical characteristic for tissue at the neural target relative to adjacent non-neural tissue.

    Abstract translation: 系统的示例包括用于放置在含有神经组织的组织上的电极片，以及被配置为测量组织的电特性的组织测试器。 组织测试器可以包括测试控制器和开关。 测试控制器和开关可以被配置为连接电极的不同组合以产生两个或更多个电极的子集，以使用子集来测量组织的电特性。 测试控制器可以被配置为使用放置在组织上的电极组内的子集来测量组织的电特性，并且比较电特性的测量并且基于对所述组合的测量的比较来识别用于治疗的神经靶标 相对于相邻非神经组织的神经靶标组织的电特性。

    Stimulation patch with passive adhesion
    5.
    发明授权
    Stimulation patch with passive adhesion 有权
    刺激贴片被动粘连

    公开(公告)号：US08965512B2

    公开(公告)日：2015-02-24

    申请号：US14104786

    申请日：2013-12-12

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Allan C. Shuros ,  Ismail Guler ,  Richard Charles Gunderson ,  Joel P. Grover ,  Eric A. Mokelke ,  Adam David Grovender

    IPC: A61N1/00 ,  A61N1/36

    CPC classification number: A61N1/36117 ,  A61N1/0558

    Abstract: System and methods for adhering a patch of stimulation electrode(s) to blood vessels to stimulate a target site on the blood vessel are described. In various embodiments, the system includes an adhesion patch and at least one electrode. The adhesion patch includes a passive adhesion mechanism that may produce an adhesive force sufficiently strong to adhere the adhesion patch to the exterior of the blood vessel and to operationally position the at least one electrode for use in electrically stimulating a target site of the blood vessel. The adhesion patch may also include a release mechanism that is configured for a user to disengage the patch from the exterior of the blood vessel without significant trauma to the blood vessel. After being released, the adhesion patch may be re-adhered to a different target site of the blood vessel and stimulate the different target site.

    Abstract translation: 描述了将一束刺激电极粘附到血管上以刺激血管上的靶位点的系统和方法。 在各种实施例中，系统包括粘附贴片和至少一个电极。 粘合贴片包括被动粘附机构，其可以产生足够强的粘附力，以将粘附贴片粘附到血管外部，并且可操作地定位所述至少一个电极以用于电刺激血管的靶位点。 粘合贴片还可以包括释放机构，该释放机构构造成使用户能够将血块从血管的外部脱离，而不会对血管造成显着的创伤。 释放后，粘附贴片可以再粘附到血管的不同靶位点并刺激不同的靶位点。

    STIMULATION PATCH WITH ACTIVE ADHESION
    6.
    发明申请
    STIMULATION PATCH WITH ACTIVE ADHESION 有权
    具有活性粘合的刺激贴

    公开(公告)号：US20140180357A1

    公开(公告)日：2014-06-26

    申请号：US14104853

    申请日：2013-12-12

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Allan C. Shuros ,  Ismail Guler ,  Richard Charles Gunderson ,  Joel P. Grover ,  Eric A. Mokelke ,  Adam Grovender

    IPC: A61N1/36

    CPC classification number: A61N1/36117 ,  A61N1/0558

    Abstract: System and methods for adhering a patch of stimulation electrode(s) to blood vessels to stimulate a target site on the blood vessel are described. In one embodiment, the system includes an adhesion patch and at least one electrode. The adhesion patch includes an active adhesion mechanism that may produce an adhesive force sufficiently strong to adhere the adhesion patch to the exterior of the blood vessel and to operationally position the at least one electrode for use in electrically stimulating a target site of the blood vessel. The adhesion patch may also include a release mechanism that is configured for a user to disengage the patch from the exterior of the blood vessel without significant trauma to the blood vessel. After being released, the adhesion patch may be re-adhered to a different target site of the blood vessel and stimulate the different target site.

    Abstract translation: 描述了将一束刺激电极粘附到血管上以刺激血管上的靶位点的系统和方法。 在一个实施例中，系统包括粘附贴片和至少一个电极。 粘合贴片包括主动粘合机构，其可以产生足够强的粘附力，以将粘附贴片粘附到血管外部，并且可操作地定位用于电刺激血管的靶位点的至少一个电极。 粘合贴片还可以包括释放机构，该释放机构构造成使用户能够将血块从血管的外部脱离，而不会对血管造成显着的创伤。 释放后，粘附贴片可以再粘附到血管的不同靶位点并刺激不同的靶位点。

    Apparatus for baroreceptor stimulation therapy
    7.
    发明授权
    Apparatus for baroreceptor stimulation therapy 有权

    公开(公告)号：US10029091B2

    公开(公告)日：2018-07-24

    申请号：US14627380

    申请日：2015-02-20

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Eric A. Mokelke ,  Shantha Arcot-Krishnamurthy ,  Brian Soltis ,  Jason J. Hamann

    IPC: A61N1/05 ,  A61N1/36

    Abstract: A medical apparatus comprising an implantable lead and a stylet configured for stimulation of a target region of a patient's nervous system is described. The lead includes a generally tubular lead body, a conductor, and an electrode assembly. The generally tubular lead body has a stylet lumen and a conductor lumen extending through the proximal and distal ends of the lead body. The conductor is enclosed within the conductor lumen. The electrode assembly extends from the distal end of the lead body. The electrode assembly includes a flexible polymeric carrier and an electrode on the carrier and electrically coupled to the conductor. The stylet is sized and shaped to be receivable within the stylet lumen and configured to stiffen and support the lead body. The distal portion of the stylet includes a bend having a predetermined angle of incidence relative to the proximal portion of the stylet.

    BARORECEPTOR MAPPING SYSTEM
    9.
    发明申请
    BARORECEPTOR MAPPING SYSTEM 有权
    BARORECEPTOR映射系统

    公开(公告)号：US20150366465A1

    公开(公告)日：2015-12-24

    申请号：US14743954

    申请日：2015-06-18

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Andrew L. De Kock ,  Eric A. Mokelke ,  Brian Soltis ,  Doug E. Giwoyna ,  James E. Blood

    IPC: A61B5/021 ,  A61B5/053 ,  A61B5/00 ,  A61B5/024

    CPC classification number: A61B5/021 ,  A61B5/02028 ,  A61B5/0215 ,  A61B5/024 ,  A61B5/053 ,  A61B5/0531 ,  A61B5/4848 ,  A61B5/6876 ,  A61B90/39 ,  A61B2090/3908 ,  A61N1/0476 ,  A61N1/0556 ,  A61N1/0558 ,  A61N1/36117 ,  A61N1/36185 ,  Y10T156/1028

    Abstract: A system for mapping and marking baroreceptors of a patient. The system includes a mapping device, a marker, and a stimulator. The mapping device includes a plurality of electrodes to be situated on the patient. The marker is to be attached to the patient and mark a location of at least one of the plurality of electrodes based on an analysis of patient physiological responses to stimulation of the plurality of electrodes. The stimulator is to divide the plurality of electrodes into a first electrode zone and a second electrode zone and stimulate electrodes in the first electrode zone and the second electrode zone to obtain first patient physiological responses, where one of the first electrode zone and the second electrode zone is selected based on the first patient physiological responses.

    Abstract translation: 用于映射和标记患者的压力感受器的系统。 该系统包括映射设备，标记和刺激器。 该测绘装置包括位于患者身上的多个电极。 基于对多个电极的刺激的患者生理反应的分析，将标记附接到患者并标记多个电极中的至少一个的位置。 刺激器是将多个电极分成第一电极区域和第二电极区域，并且在第一电极区域和第二电极区域中刺激电极以获得第一患者生理反应，其中第一电极区域和第二电极中的一个 基于第一个患者生理反应选择区域。

    Hypertension therapy device with longevity management
    10.
    发明授权
    Hypertension therapy device with longevity management 有权
    高血压治疗器具长寿管理

    公开(公告)号：US09101770B2

    公开(公告)日：2015-08-11

    申请号：US14185737

    申请日：2014-02-20

    Applicant: Cardiac Pacemakers, Inc.

    Inventor： Shantha Arcot-Krishnamurthy ,  Eric A. Mokelke ,  David J. Ternes

    IPC: A61N1/00 ,  A61N1/36 ,  A61N1/372

    CPC classification number: A61N1/36117 ,  A61N1/36139 ,  A61N1/36167 ,  A61N1/36175 ,  A61N1/36178 ,  A61N1/37235

    Abstract: System and methods for programming and delivering electrical stimulation to treat hypertension are discussed. In various embodiments, an ambulatory stimulator system, such as an implantable medical device, can receive a power-saving command and deliver the electrical stimulation to a target site in a patient according to one or more simulation parameters including a therapy on-off pattern. In some embodiments, stimulation with therapy on-off pattern can reduce the power consumption while maintaining the anti-hypertension therapy efficacy. In some embodiments, the ambulatory stimulator system can include one or more of a physiologic response detector, a patient status detector, or a battery longevity detector. The power-saving command can be generated using one or more of the detected physiologic signal, the patient status, or the information about the battery longevity.

    Abstract translation: 讨论了编程和传递电刺激治疗高血压的系统和方法。 在各种实施例中，诸如可植入医疗装置的动态刺激器系统可以接收功率节省命令，并且根据包括治疗开 - 关模式的一个或多个模拟参数将电刺激递送到患者中的目标部位。 在一些实施方案中，用治疗开 - 关模式的刺激可以降低功耗，同时保持抗高血压治疗功效。 在一些实施例中，动态刺激器系统可以包括生理响应检测器，患者状态检测器或电池寿命检测器中的一个或多个。 可以使用检测到的生理信号，患者状态或关于电池寿命的信息中的一个或多个生成省电命令。

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