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1.发明公开公开(公告)号：US20240120094A1
公开(公告)日：2024-04-11
申请号：US18263162
申请日：2022-01-26
发明人： Hendrik BURWINKEL , Holger MATZ , Stefan SAUR , Christoph HAUGER
摘要： A computer-implemented method for determining the refractive power of an intraocular lens includes providing a physical model for determining refractive power and training a machine learning system with clinical ophthalmological training data and associated desired results to form a learning model for determining the refractive power. A loss function for training includes: a first component taking into account clinical ophthalmological training data and associated and desired results and a second component taking into account limitations of the physical model wherein a loss function component value is greater the further a predicted value of the refractive power during the training is from results of the physical model with the same clinical ophthalmological training data as input values. Moreover, the method includes providing ophthalmological data of a patient and predicting the refractive power of the intraocular lens to be used by means of the trained machine learning system.
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公开(公告)号：US20160139391A1
公开(公告)日：2016-05-19
申请号：US14940639
申请日：2015-11-13
发明人： Christoph HAUGER , Roland GUCKLER
CPC分类号： G02B21/0012 , A61B5/0071 , G02B5/28 , G02B21/16 , G02B21/18 , G02B21/22
摘要： An optical system for fluorescence observation comprises optics including an ocular 17, a camera 55, a display 69, a light source 71, an illumination light filter 84, an observation light filter 57 and a controller 35. The observation filter has multiple transmitting regions which allows light which was generated by a fluorescence to traverse for observation. The transmitting ranges are divided by blocking ranges. At the wavelength ranges at which the observation filter has a transmitting region the illumination filter has a blocking region and the other way round. The multiple transmitting regions of the illumination filter enable an improved color impression under normal light observation.The controller is configured to process a fluorescent light image obtained by the camera by identifying a contiguous fluorescent region in the fluorescent light image, generating an image including a representation of the boundary of the contiguous fluorescent region, and supplying the generated image to the display.
摘要翻译： 用于荧光观察的光学系统包括光学器件，其包括眼17，相机55，显示器69，光源71，照明光滤波器84，观察光滤波器57和控制器35.观察滤波器具有多个发射区域 允许由荧光产生的光穿过观察。 发送范围除以阻塞范围。 在观察滤波器具有透射区域的波长范围内，照明滤光器具有阻挡区域，而另一方面。 照明滤光片的多个发射区域能够在正常光线观察下实现改善的彩色印象。 控制器被配置为通过识别荧光图像中的连续荧光区域来处理由照相机获得的荧光图像，生成包括邻接荧光区域的边界的表示的图像，并将生成的图像提供给显示器。
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公开(公告)号：US20160095514A1
公开(公告)日：2016-04-07
申请号：US14873337
申请日：2015-10-02
发明人： Günter MECKES , Konstantinos FILIPPATOS , Thomas SCHUHRKE , Christoph HAUGER , Abouzar ESLAMI , Stefan GRÄBER , Christine KOCHWAGNER , Carolin SCHIELE , Christopher KÄSBACH
摘要： An ophthalmologic system comprising and eye tracker and an OCT system. A method of operating the ophthalmologic system comprises: providing data representing a placement of a first B-scan performed on an eye relative to the eye; performing a measurement on the eye using the eye tracker; determining a placement of the eye relative to the ophthalmologic system based on the measurement using the eye tracker; placing the eye relative to a reference placement of the OCT system based on the provided data and the determined placement; performing A-scans on the eye at at least three A-scan positions; determining a placement of a second B-scan relative to the OCT system based on at least one of the at least three A-scans and the provided data such that the second B-scan and the first B-scan have a substantially same placement relative to the eye; and generating a representation of the second B-scan.
摘要翻译： 眼科系统包括眼睛跟踪器和OCT系统。 操作眼科系统的方法包括：提供表示相对于眼睛在眼睛上执行的第一B扫描的放置的数据; 使用眼动仪对眼睛进行测量; 基于使用眼动仪的测量来确定眼睛相对于眼科系统的位置; 基于提供的数据和确定的放置，将眼睛相对于OCT系统的参考位置放置; 在至少三个A扫描位置对眼睛进行A扫描; 基于所述至少三个A扫描和所提供的数据中的至少一个来确定相对于所述OCT系统的第二B扫描的布置，使得所述第二B扫描和所述第一B扫描具有基本相同的位置相对 到眼睛 以及生成所述第二B扫描的表示。
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公开(公告)号：US20160007848A1
公开(公告)日：2016-01-14
申请号：US14796023
申请日：2015-07-10
CPC分类号： A61B3/102 , A61B3/0025 , A61B3/0033 , A61B3/0058 , A61B3/1225 , A61B3/125 , A61B3/13 , A61B90/20 , A61B2090/3735 , A61F9/007
摘要： An eye surgery system 1 comprises microscopy optics 3 and an OCT device 5 to generate a light-optical image and an OCT image of an eye fundus 11, a controller 29 and a visualization system 13, 41, 83. The controller comprises a data interface 97 for receiving a preoperative OCT image and may control the visualization system to display a representation of the received preoperative OCT image. The controller may control the OCT device 5 to record an intraoperative OCT image and may control the visualization system to display a representation of the recorded intraoperative OCT image. The controller may adjust a magnification of the representation of the intraoperative OCT image and/or a magnification of the representation of the preoperative OCT image so that the magnifications of the representation of the intraoperative OCT image and the magnification of the representation of the preoperative OCT image are equal.
摘要翻译： 眼科手术系统1包括显微镜光学器件3和OCT装置5以产生眼底11的光学图像和OCT图像，控制器29和可视化系统13,41,83。控制器包括数据接口 97用于接收术前OCT图像，并且可以控制可视化系统以显示所接收的术前OCT图像的表示。 控制器可以控制OCT装置5记录术中OCT图像，并且可以控制可视化系统以显示所记录的术中OCT图像的表示。 控制器可以调整术中OCT图像的表示的放大倍率和/或术前OCT图像的表示的放大倍率，使得术中OCT图像的表示的放大率和术前OCT图像的表示的放大倍率 平等
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5.发明申请公开(公告)号：US20150109580A1
公开(公告)日：2015-04-23
申请号：US14579053
申请日：2014-12-22
CPC分类号： A61B3/13 , A61B3/102 , A61B3/14 , A61B90/20 , G02B21/0012
摘要： An eye surgery microscope 1 having an illumination beam path 9 for imaging a portion of an eye 3 of a patient and a measurement beam path 25 for measuring an ametropia of the eye. The microscope comprises an objective lens 11 having an objective plane 13 in which the eye of the patient is disposable; at least one ocular 17 or a camera 19 for generating and detecting an image of the object plane, respectively; a measurement light source for generating a measurement light beam 29; a measurement module 41 having a light detector; optics traversed by the measurement beam path for directing the measurement light beam onto the retina 7 of the eye of the patient and for providing measurement light 39 reflected at the retina to the measurement module; and a controller; wherein the measurement module and the controller are configured to determine a position of an image of the retina generated by the optics along the measurement beam path and to output a measurement value representing the ametropia of the eye of the patient.
摘要翻译： 具有用于对患者的眼睛3的一部分进行成像的照明光束路径9的眼科手术显微镜1和用于测量眼睛屈光不正的测量光束路径25。 显微镜包括物镜11，物镜11具有客观平面13，患者的眼睛在其中是一次性的; 至少一个目镜17或相机19，用于分别产生和检测物体平面的图像; 用于产生测量光束29的测量光源; 具有光检测器的测量模块41; 用于将测量光束引导到患者眼睛的视网膜7上并用于将在视网膜处反射的测量光39提供给测量模块的由测量光束路径穿过的光学元件; 和控制器; 其中所述测量模块和所述控制器被配置为确定由所述光学器件沿着所述测量光束路径产生的所述视网膜的图像的位置，并且输出表示所述患者眼睛的屈光不正的测量值。
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公开(公告)号：US20140362343A1
公开(公告)日：2014-12-11
申请号：US14299488
申请日：2014-06-09
发明人： Christoph HAUGER , Holger MATZ , Anja SEIWERT
CPC分类号： A61B3/13 , A61B3/0008 , G02B21/0012 , G02B21/16 , G02B21/22
摘要： An ophthalmology microscopy system for observing fluorescence comprises an imaging system and an illumination system. The imaging system provides at least one optical imaging path producing a magnified multi-dimensional image of an object disposable in a focal plane of the imaging system, and comprises at least one optical observation filter. The illumination system provides an illumination beam path intersecting the focal plane of the imaging system at a variable angle of less than 90°. The microscopy system comprises first and second operating states. In the first operating state, radiation passing through the illumination beam path has at least in a section along the illumination beam path a spectrum free of a pass band of the observation filter. In the second operating state, radiation passing through the illumination beam path has a spectrum having a bandwidth of at least 200 nm in a range from 380 nm to 780 nm.
摘要翻译： 用于观察荧光的眼科显微镜系统包括成像系统和照明系统。 所述成像系统提供至少一个光学成像路径，其产生在所述成像系统的焦平面中一次性使用的物体的放大多维图像，并且包括至少一个光学观察滤光器。 照明系统以小于90°的可变角度提供与成像系统的焦平面相交的照明光束路径。 显微镜系统包括第一和第二操作状态。 在第一操作状态下，穿过照明光束路径的辐射至少在沿着照明光束路径的部分中没有观察滤光器的通带的光谱。 在第二操作状态下，穿过照明光束路径的辐射具有在380nm至780nm的范围内具有至少200nm的带宽的光谱。
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公开(公告)号：US20220160454A1
公开(公告)日：2022-05-26
申请号：US17529041
申请日：2021-11-17
发明人： Stefan SAUR , Christoph HAUGER , Christoph SCHAEFF
摘要： The invention relates to a method for operating an augmented reality observation system in a surgical application, wherein a viewing direction of a user is registered by means of a viewing direction sensor system of an AR observation apparatus, wherein the registered viewing direction is evaluated by means of a control device, and wherein at least one property of at least one controllable light source in the environment is altered by means of the control device by means of a control signal on the basis of the registered viewing direction. Further, the invention relates to an augmented reality observation system for a surgical application.
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公开(公告)号：US20180177637A1
公开(公告)日：2018-06-28
申请号：US15902323
申请日：2018-02-22
发明人： Christoph HAUGER
摘要： A surgical instrument system for ophthalmic surgery in an eye is provided, comprising: an OCT apparatus including an interferometer; an optical fiber coupled to the OCT apparatus and extending a probe arm of the interferometer; a hand tool comprising: a hand piece, a tube extending away from the hand piece and comprising a distal end portion having a longitudinal axis, wherein a distal portion of the optical fiber is received within the tube; a beam emitter coupled to a tip end of the optical fiber and configured to emit an OCT measuring beam into an emission direction; and an actuator configured to change the emission direction of the OCT measuring beam relative to a tip end of the distal end portion.
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公开(公告)号：US20150077708A1
公开(公告)日：2015-03-19
申请号：US14549058
申请日：2014-11-20
CPC分类号： A61B3/102 , A61B3/005 , A61B3/117 , A61B3/12 , A61B3/1225 , A61B3/13 , A61B3/14 , G01B9/02004 , G01B9/0203 , G01B9/02035 , G01B9/02044 , G01B9/02091 , G02B7/14 , G02B27/0955
摘要： Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.
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公开(公告)号：US20150002814A1
公开(公告)日：2015-01-01
申请号：US14319050
申请日：2014-06-30
CPC分类号： G02B21/14 , G02B7/28 , G02B21/0012
摘要： Disclosed is a microscope system for imaging an object within an eye, wherein the object is a phase object. The microscope system includes imaging optics for generating images of an object plane of the imaging optics in an image plane of the imaging optics by using imaging light. The object plane is optically conjugate to the image plane. The microscope system is configured to store focus shift data representing a focus shift. The focus shift is generated by a different effect on the imaging light generated by phase objects as compared to amplitude objects. The microscope system is configured to image the object depending on the focus shift data.
摘要翻译： 公开了一种用于对眼睛内的物体进行成像的显微镜系统，其中物体是相位物体。 显微镜系统包括成像光学器件，用于通过使用成像光在成像光学器件的图像平面中产生成像光学元件的物体平面的图像。 物平面与图像平面光学共轭。 显微镜系统被配置为存储表示聚焦偏移的聚焦移动数据。 与幅度对象相比，由相位对象产生的成像光产生不同的影响。 显微镜系统被配置为根据聚焦移位数据对物体进行成像。
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