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公开(公告)号：US20160139391A1
公开(公告)日：2016-05-19
申请号：US14940639
申请日：2015-11-13
发明人： Christoph HAUGER , Roland GUCKLER
CPC分类号： G02B21/0012 , A61B5/0071 , G02B5/28 , G02B21/16 , G02B21/18 , G02B21/22
摘要： An optical system for fluorescence observation comprises optics including an ocular 17, a camera 55, a display 69, a light source 71, an illumination light filter 84, an observation light filter 57 and a controller 35. The observation filter has multiple transmitting regions which allows light which was generated by a fluorescence to traverse for observation. The transmitting ranges are divided by blocking ranges. At the wavelength ranges at which the observation filter has a transmitting region the illumination filter has a blocking region and the other way round. The multiple transmitting regions of the illumination filter enable an improved color impression under normal light observation.The controller is configured to process a fluorescent light image obtained by the camera by identifying a contiguous fluorescent region in the fluorescent light image, generating an image including a representation of the boundary of the contiguous fluorescent region, and supplying the generated image to the display.
摘要翻译： 用于荧光观察的光学系统包括光学器件，其包括眼17，相机55，显示器69，光源71，照明光滤波器84，观察光滤波器57和控制器35.观察滤波器具有多个发射区域 允许由荧光产生的光穿过观察。 发送范围除以阻塞范围。 在观察滤波器具有透射区域的波长范围内，照明滤光器具有阻挡区域，而另一方面。 照明滤光片的多个发射区域能够在正常光线观察下实现改善的彩色印象。 控制器被配置为通过识别荧光图像中的连续荧光区域来处理由照相机获得的荧光图像，生成包括邻接荧光区域的边界的表示的图像，并将生成的图像提供给显示器。
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公开(公告)号：US20230080925A1
公开(公告)日：2023-03-16
申请号：US17793805
申请日：2021-02-02
发明人： Ady NABER , Werner NAHM , Christoph HAUGER , Roland GUCKLER
摘要： The invention relates to a computer-implemented method (10) for determining the blood volume flow (IBI) through a portion (90i, i=1, 2, 3, . . . ) of a blood vessel (88) in an operating region (36) using a fluorophore. A plurality of images (801, 802, 803, 804, . . . ) are provided, which are based on fluorescent light in the form of light having wavelengths lying within a fluorescence spectrum of the fluorophore, and which show the portion (90i) of the blood vessel (88) at different recording times (t1, t2, t3, t4, . . . ). By processing at least one of the provided images (801, 802, 803, 804, . . . ), a diameter (D) and a length (L) of the portion (90i) of the blood vessel (88) and also a time interval for a propagation of the fluorophore through the portion (90i) of the blood vessel (88) are determined, which time interval describes a characteristic transit time (τ) for the fluorophore in the portion (90i) of the blood vessel (88), in which a blood vessel model (MBQ) for the portion (90i) of the blood vessel (88) is specified, which blood vessel model describes the portion (90i) of the blood vessel (88) as a flow channel (94) having a length (L), having a wall (95) with a wall thickness (d), and having a free cross section Q. A fluid flow model MFQ for the blood vessel model (MBQ) is assumed, which fluid flow model describes a local flow velocity (122) at different positions over the free cross section Q of the flow channel (94) in the blood vessel model (MBQ), and a fluorescent light model MLQ is assumed, which describes a spatial probability density for the intensity of the remitted light at different positions over the free cross section Q of the flow channel (94) in the blood vessel model (MBQ), which light is emitted by a fluid, which is mixed with fluorophore and flows through the free cross section Q of the flow channel (94) in the blood vessel model (MBQ), when said fluid is irradiated with fluorescence excitation light. The blood volume flow (IBI) is determined as a fluid flow guided through the flow channel (94) in the blood vessel model (MBQ), which fluid flow is calculated from the length (L) and the diameter (D) of the portion (90i) of the blood vessel (88) and from the characteristic transit time (τ) for the fluorophore in the portion (90i) of the blood vessel (88), using the fluid flow model MFQ and the fluorescent light model MLQ.
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公开(公告)号：US20180303318A1
公开(公告)日：2018-10-25
申请号：US15950715
申请日：2018-04-11
发明人： Martin FANENBRUCK , Helge JESS , Roland GUCKLER
CPC分类号： A61B1/00066 , A61B1/00112
摘要： An endoscopic probe is made available. Said endoscopic probe comprises: a handle with a front end a rear end with a rear end axis and, extending between the front end and the rear end, a straight grip portion with a grip portion axis; a shaft extending from the front end of the handle and having a shaft axis, and a cable issuing from the rear end, wherein the shaft axis, the rear end axis and the grip portion axis lie within a common plane, the shaft axis encloses an angle in the range of 100 to 140 degrees with the grip portion axis, the grip portion axis encloses an angle in the range of 110 to 130 degrees with the rear end axis, the shaft axis encloses an angle in the range of 30 to 90 degrees with the rear end axis.
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公开(公告)号：US20150346098A1
公开(公告)日：2015-12-03
申请号：US14722265
申请日：2015-05-27
发明人： Christoph HAUGER , Roland GUCKLER , Marco WILZBACH , Helge JESS , Selamawit Getachew KELEMU , Holger MATZ
CPC分类号： G01N21/6458 , G01N2021/6471 , G02B5/208 , G02B5/22 , G02B21/0076 , G02B21/16
摘要： An optical filter system for florescence observation comprises an illumination light filter (I) and an observation light filter (O). The observation light filter has plural transmitting regions (D1O,D2O) allowing fluorescent light to traverse the observation light filter. Blocking regions (S0O,S1O) separate the transmitting regions. The illumination light filter has transmitting regions (D0I,D1I) where the observation light filter has a corresponding blocking region. The illumination light filter has blocking regions (S1I,S2I) where the observation light filter has a corresponding transmitting region. The plural transmitting regions of the illumination light filter hallow for an improved color impression in the normal light observation.
摘要翻译： 用于荧光观察的滤光器系统包括照明光滤光器（I）和观察光过滤器（O）。 观察光滤波器具有允许荧光穿过观察滤光器的多个透射区域（D1O，D2O）。 阻挡区域（S0O，S1O）分离发射区域。 照明光滤波器具有发送区域（D0I，D1I），其中观察光滤波器具有对应的阻挡区域。 照明光滤波器具有阻挡区域（S1I，S2I），其中观察光滤波器具有相应的发射区域。 照明光过滤器的多个透射区域在正常光观察中为了改善的颜色印象。
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5.发明公开公开(公告)号：US20240252276A1
公开(公告)日：2024-08-01
申请号：US18414998
申请日：2024-01-17
CPC分类号： A61B90/361 , A61B90/20 , G06V20/695 , H04N5/265 , A61B2090/364 , A61B2090/373
摘要： The invention relates to a method for providing an image representation by means of a surgical microscope, comprising obtaining or capturing at least one application parameter, capturing a color image representation of a capture region by means of a camera, capturing a fluorescence image representation of the capture region by means of a fluorescence camera, processing the fluorescence image representation by means of a processing device to optimize it for an overlay with the color image representation, wherein a type of processing is defined based on the at least one application parameter, overlaying the color image representation with the processed fluorescence image representation, and providing an image signal that encodes the overlaid image representation. The invention further relates to a surgical microscope.
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6.发明申请LIQUIDS AND GELS FOR THE OPHTHALMOLOGY AND MICROSCOPY SYSTEM FOR OBSERVING THE SAME 有权用于观察其的眼科学和微观系统的液体和凝胶公开(公告)号：US20150119835A1
公开(公告)日：2015-04-30
申请号：US14524341
申请日：2014-10-27
CPC分类号： A61M1/0031 , A61B3/102 , A61B3/13 , A61F9/00745 , A61F2009/00887 , A61K49/0423 , A61M1/0064
摘要： Embodiments relate to an ophthalmology microscopy-system and a method of operating an ophthalmology microscopy-system which allow for an at least partial or full removal of liquids and gels used in ophthalmology for application in an eye of a patient in an particularly efficient way. Further embodiments relate to a product such as a liquid or a gel usable for an application in an eye of a patient, wherein the product has a high transmittance and, nevertheless, may be made visible particularly well.
摘要翻译： 实施例涉及眼科学显微镜系统和操作眼科学显微系统的方法，其允许以特别有效的方式在眼科中使用的液体和凝胶至少部分或全部去除以应用于患者的眼睛。 另外的实施方案涉及可用于在患者眼睛中施用的液体或凝胶的产品，其中产品具有高透射率，并且可以使其可见特别好。
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公开(公告)号：US20140211306A1
公开(公告)日：2014-07-31
申请号：US14242339
申请日：2014-04-01
发明人： Helge JESS , Roland GUCKLER
CPC分类号： G02B21/06 , G01J3/0235 , G01J3/4406 , G01N21/64 , G01N21/6447 , G01N21/6458 , G02B5/20 , G02B5/288 , G02B21/0076 , G02B21/16
摘要： A set of filters for fluorescence observation comprises an illumination light filter and an observation light filter, wherein the following is holds: ∫ S T L ( r -> ) · T O ( r -> ) · r -> · r ∫ S T L ( r -> ) · T O ( r -> ) · r = R -> and ( 3 ) W -> - R -> ≤ 0.2 ; ( 4 ) wherein: λ designates the wavelength, TL(λ) is the transmission characteristic of the illumination light filter, TO(λ) is the transmission characteristic of the observation light filter, and A1, A2 are numbers between 0 and 1, {right arrow over (r)} is a coordinate in the CIE xy chromaticity diagram of the CIE 1931 XYZ color space, S is a line called the spectral locus in the CIE xy chromaticity diagram of the CIE 1931 XYZ color space, and {right arrow over (W)} is the white point in the CIE xy chromaticity diagram of the CIE 1931 XYZ color space.
摘要翻译： 用于荧光观察的一组滤光器包括照明光滤光器和观察光滤光片，其中以下是：∫S TL（r->）·TO（r->）·r···∫r∫ （r - >）·r = R→>>≤≤≤≤ （4）其中：λ表示波长，TL（λ）是照明光滤波器的透射特性，TO（λ）是观察光滤波器的透射特性，A1，A2是0和1之间的数，{ 右侧箭头（r）}是CIE 1931 XYZ色彩空间的CIE xy色度图中的坐标，S是CIE 1931 XYZ色彩空间的CIE xy色度图中称为光谱轨迹的线，{右箭头 over（W）}是CIE 1931 XYZ色彩空间的CIE xy色度图中的白点。
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