Sealing a pharmaceutical formulation in a package
    5.
    发明申请
    Sealing a pharmaceutical formulation in a package 审中-公开
    在包装中密封药物制剂

    公开(公告)号:US20050051453A1

    公开(公告)日:2005-03-10

    申请号:US10301820

    申请日:2002-11-20

    摘要: An apparatus is provided for sealing a first layer to a second layer, the second layer comprising one or more cavities adapted to contain a pharmaceutical formulation. The apparatus comprises a roller comprising a heating element, and a surface adapted to support the first and second layers, the surface being translatable relative to the roller. The first layer may be heat sealed to the second layer when contacted by the roller to contain the pharmaceutical formulation within the one or more cavities.

    摘要翻译: 提供了用于将第一层密封到第二层的设备,第二层包括适于容纳药物制剂的一个或多个空腔。 该装置包括一个包括加热元件的滚子和适于支撑第一和第二层的表面,该表面可相对于滚子平移。 当与辊接触时,第一层可以热密封到第二层,以在一个或多个空腔内容纳药物制剂。

    Increased dosage metered dose inhaler
    6.
    发明授权
    Increased dosage metered dose inhaler 有权
    增加剂量计量剂量吸入器

    公开(公告)号:US07481212B2

    公开(公告)日:2009-01-27

    申请号:US10698025

    申请日:2003-10-30

    IPC分类号: A61M11/00

    CPC分类号: B65D83/54 A61M15/009

    摘要: An aerosolization apparatus comprises a container containing a pharmaceutical formulation, the pharmaceutical formulation comprising an active agent and a propellant. The aerosolization apparatus further comprises a metering chamber in communication with the container, the metering chamber adapted to hold a metered amount of the pharmaceutical formulation, a valve to allow the metered amount of the pharmaceutical formulation to be released from the metering chamber when the valve is actuated, and a pressurizer that applies pressure to the pharmaceutical formulation in the metering chamber while the pharmaceutical formulation is being released from the metering chamber. In one version, the metering chamber is sized so that at least 2 mg, and preferably at least 5 mg, of the active agent is be aerosolized for delivery to a user during inhalation.

    摘要翻译: 雾化装置包括容纳药物制剂的容器,药物制剂包含活性剂和推进剂。 雾化装置还包括与容器连通的计量室,计量室适于容纳计量量的药物制剂,阀,以允许计量量的药物制剂在计量室内从计量腔室释放时,阀门为 以及当药物制剂从计量室释放时向计量室中的药物制剂施加压力的加压器。 在一个版本中,计量室的尺寸设定为使得至少2mg,优选至少5mg的活性剂被雾化以在吸入期间输送给使用者。

    Metered dose inhaler with lockout
    7.
    发明申请
    Metered dose inhaler with lockout 有权
    计量吸入器锁定

    公开(公告)号:US20050056276A1

    公开(公告)日:2005-03-17

    申请号:US10734076

    申请日:2003-12-10

    IPC分类号: A61M15/00 A61M11/00

    摘要: An aerosolization device comprises a housing, a container comprising a reservoir storing a pharmaceutical formulation which comprises a propellant, and a metering valve. The metering valve is in communication with the reservoir and is moveable into the container to an actuated position where a predetermined amount of the pharmaceutical formulation is released. A contact member is provided in the housing. In one version, the contact member is moveable between a first position and a second position to allow for selective actuation of the metering valve. In another version, the contact member's configuration may be changed to allow for selective actuation of the metering valve.

    摘要翻译: 雾化装置包括壳体,容器,其包含储存包含推进剂的药物制剂的储存器和计量阀。 计量阀与储存器连通并且可移动到容器中到达预定量的药物制剂被释放的致动位置。 接触构件设置在壳体中。 在一个版本中,接触构件可在第一位置和第二位置之间移动,以允许选择性地致动计量阀。 在另一个版本中,可以改变接触构件的构造以允许选择性地致动计量阀。

    Increased dosage metered dose inhaler
    8.
    发明授权
    Increased dosage metered dose inhaler 有权
    增加剂量计量剂量吸入器

    公开(公告)号:US08079361B2

    公开(公告)日:2011-12-20

    申请号:US12337584

    申请日:2008-12-17

    IPC分类号: A61M11/00

    CPC分类号: B65D83/54 A61M15/009

    摘要: An aerosolization apparatus comprises a container containing a pharmaceutical formulation, the pharmaceutical formulation comprising an active agent and a propellant. The aerosolization apparatus further comprises a metering chamber in communication with the container, the metering chamber adapted to hold a metered amount of the pharmaceutical formulation, a valve to allow the metered amount of the pharmaceutical formulation to be released from the metering chamber when the valve is actuated, and a pressurizer that applies pressure to the pharmaceutical formulation in the metering chamber while the pharmaceutical formulation is being released from the metering chamber. In one version, the metering chamber is sized so that at least 2 mg, and preferably at least 5 mg, of the active agent is be aerosolized for delivery to a user during inhalation.

    摘要翻译: 雾化装置包括容纳药物制剂的容器,药物制剂包含活性剂和推进剂。 雾化装置还包括与容器连通的计量室,计量室适于容纳计量量的药物制剂,阀,以允许计量量的药物制剂在计量室内从计量腔室释放时,阀门为 以及当药物制剂从计量室释放时向计量室中的药物制剂施加压力的加压器。 在一个版本中,计量室的尺寸设定为使得至少2mg,优选至少5mg的活性剂被雾化以在吸入期间输送给使用者。

    Increased Dosage Metered Dose Inhaler
    9.
    发明申请
    Increased Dosage Metered Dose Inhaler 有权
    增加剂量计量吸入器

    公开(公告)号:US20090095289A1

    公开(公告)日:2009-04-16

    申请号:US12337584

    申请日:2008-12-17

    IPC分类号: A61M11/00 A61K38/28 A61P43/00

    CPC分类号: B65D83/54 A61M15/009

    摘要: An aerosolization apparatus comprises a container containing a pharmaceutical formulation, the pharmaceutical formulation comprising an active agent and a propellant. The aerosolization apparatus further comprises a metering chamber in communication with the container, the metering chamber adapted to hold a metered amount of the pharmaceutical formulation, a valve to allow the metered amount of the pharmaceutical formulation to be released from the metering chamber when the valve is actuated, and a pressurizer that applies pressure to the pharmaceutical formulation in the metering chamber while the pharmaceutical formulation is being released from the metering chamber. In one version, the metering chamber is sized so that at least 2 mg, and preferably at least 5 mg, of the active agent is be aerosolized for delivery to a user during inhalation.

    摘要翻译: 雾化装置包括容纳药物制剂的容器,药物制剂包含活性剂和推进剂。 雾化装置还包括与容器连通的计量室,计量室适于容纳计量量的药物制剂,阀,以允许计量量的药物制剂在计量室内从计量腔室释放时,阀门为 以及当药物制剂从计量室释放时向计量室中的药物制剂施加压力的加压器。 在一个版本中,计量室的尺寸设定为使得至少2mg,优选至少5mg的活性剂被雾化以在吸入期间输送给使用者。

    Increased dosage metered dose inhaler
    10.
    发明申请
    Increased dosage metered dose inhaler 有权
    增加剂量计量剂量吸入器

    公开(公告)号:US20050051162A1

    公开(公告)日:2005-03-10

    申请号:US10698025

    申请日:2003-10-30

    IPC分类号: A61M15/00 B65D83/14 A61M11/00

    CPC分类号: B65D83/54 A61M15/009

    摘要: An aerosolization apparatus comprises a container containing a pharmaceutical formulation, the pharmaceutical formulation comprising an active agent and a propellant. The aerosolization apparatus further comprises a metering chamber in communication with the container, the metering chamber adapted to hold a metered amount of the pharmaceutical formulation, a valve to allow the metered amount of the pharmaceutical formulation to be released from the metering chamber when the valve is actuated, and a pressurizer that applies pressure to the pharmaceutical formulation in the metering chamber while the pharmaceutical formulation is being released from the metering chamber. In one version, the metering chamber is sized so that at least 2 mg, and preferably at least 5 mg, of the active agent is be aerosolized for delivery to a user during inhalation.

    摘要翻译: 雾化装置包括容纳药物制剂的容器,药物制剂包含活性剂和推进剂。 雾化装置还包括与容器连通的计量室,计量室适于容纳计量量的药物制剂,阀,以允许计量量的药物制剂在计量室内从计量腔室释放时,阀门为 以及当药物制剂从计量室释放时向计量室中的药物制剂施加压力的加压器。 在一个版本中,计量室的尺寸设定为使得至少2mg,优选至少5mg的活性剂被雾化以在吸入期间输送给使用者。