公开(公告)号：US20170174862A1

公开(公告)日：2017-06-22

申请号：US15383206

申请日：2016-12-19

Applicant: Case Western Reserve University

Inventor： Gary E. Wnek ,  Anne Walker ,  Maria Vratsanos

IPC: C08K3/16 ,  C08J3/24

CPC classification number: C08K3/16 ,  C08F265/06 ,  C08J3/075 ,  C08J2333/02 ,  C08K5/20 ,  C08K2003/162 ,  C08K2003/166 ,  C08K2003/168 ,  C09J4/06 ,  C09J133/02 ,  C08L33/02 ,  C08F222/385

Abstract: Disclosed herein are novel materials and methods of forming those novel materials. The materials are synthesized from Poly(acrylic acid), a crosslinker; and a salt. The material can be further synthesized from sodium hydroxide. The crosslinker can be a covalent crosslinking agent such as N,N′-methylenebisacrylamide. Examples of applicable salts are calcium chloride, lithium chloride, zinc chloride, sodium chloride, potassium chloride, barium chloride, cesium chloride, magnesium chloride, cobalt chloride, lithium bromide. In example, the Poly(acrylic acid) can be about 3 moles of Poly(acrylic acid), the crosslinker can be about 0.005 moles of N,N′-methylenebisacrylamide, and the salt can be formed by the addition of about 0.003 moles of potassium persulfate.

公开(公告)号：US10604636B2

公开(公告)日：2020-03-31

申请号：US15383206

申请日：2016-12-19

Applicant: Case Western Reserve University

Inventor： Gary E. Wnek ,  Anne Walker ,  Maria Vratsanos

IPC: C08F20/06 ,  C08L33/02 ,  C08K3/16 ,  C08J3/075 ,  C09J133/02 ,  C08F265/06 ,  C08K5/20 ,  C09J4/06

Abstract: Disclosed herein are novel materials and methods of forming those novel materials. The materials are synthesized from Poly(acrylic acid), a crosslinker; and a salt. The material can be further synthesized from sodium hydroxide. The crosslinker can be a covalent crosslinking agent such as N,N′-methylenebisacrylamide. Examples of applicable salts are calcium chloride, lithium chloride, zinc chloride, sodium chloride, potassium chloride, barium chloride, cesium chloride, magnesium chloride, cobalt chloride, lithium bromide. In example, the Poly(acrylic acid) can be about 3 moles of Poly(acrylic acid), the crosslinker can be about 0.005 moles of N,N′-methylenebisacrylamide, and the salt can be formed by the addition of about 0.003 moles of potassium persulfate.

公开(公告)号：US20170260341A1

公开(公告)日：2017-09-14

申请号：US15457969

申请日：2017-03-13

Applicant: Case Western Reserve University

Inventor： Anne Walker ,  Gary E. Wnek

IPC: C08J3/24 ,  C09D109/02 ,  C09D183/06

CPC classification number: C08J3/24 ,  B33Y70/00 ,  C08G77/14 ,  C08J3/28 ,  C08J2309/02 ,  C08J2315/00 ,  C08J2383/06 ,  C09D183/06

Abstract: Disclosed herein is a method of forming a photocurable polymer system. The method includes providing a polymer, providing a diaryl iodonium salt, blending said polymer and diaryl iodonium salt, applying the blend to a substrate; and crosslinking the blend. The polymer can be a silicone-based polymer, such as PDMS-ECHE. The polymer can also be ETBN. The blend can be crosslinked by exposing the blend to ultraviolet light, and the crosslinking can be cationic crosslinking. In one example, the wavelength of the ultraviolet light is 254 nm. The blend can be exposed to ultraviolet light for between about 10 seconds and 90 seconds. In one example, the blend is two percent by weight of the diaryl iodonium salt to the polymer.

公开(公告)号：US20160319414A1

公开(公告)日：2016-11-03

申请号：US15141747

申请日：2016-04-28

Applicant: Case Western Reserve University

Inventor： Anne Walker ,  Gary E. Wnek

IPC: C23C2/00 ,  C09D133/02

CPC classification number: C23C2/00 ,  C08F222/385 ,  C08L33/02 ,  C09D133/02

Abstract: In one embodiment, PAA is immobilized on dry, solid, fibrous media, such as cellulose fiber paper (“PAA-CF”) to yield a robust, flexible material with substantial wicking and fluid uptake capabilities. PAA-CF materials demonstrate the ability for use as collection and storage devices for applications such as dried blood spot analysis, protein and DNA preservation and analysis, enzymatic assays, biomarker identification, and other processes used for biological materials. PAA-CF materials can readily take up whole blood, plasma, proteins, and solutions of molecules that can then be easily extracted and analyzed.

Abstract translation: 在一个实施方案中，将PAA固定在干燥，固体，纤维介质如纤维素纤维纸（“PAA-CF”）上，以产生具有显着芯吸和流体吸收能力的坚固且柔性的材料。 PAA-CF材料显示了用作收集和储存装置的能力，例如干血斑分析，蛋白质和DNA保存和分析，酶测定，生物标志物鉴定和用于生物材料的其他过程。 PAA-CF材料可以容易地吸收全血，血浆，蛋白质和分子溶液，然后可以容易地提取和分析。