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13 条记录 (耗时 0.046 秒)

    Analyte injection system
    1.
    发明申请
    Analyte injection system 审中-公开
    分析物注射系统

    公开(公告)号：US20050133370A1

    公开(公告)日：2005-06-23

    申请号：US10865959

    申请日：2004-06-12

    申请人： Charles Park ,  Persefoni Kechagia ,  Michael Spaid ,  Morten Jensen ,  Irina Kazakova ,  Josh Molho ,  Tomohisa Kawabata ,  Mitsuo Watanabe

    发明人： Charles Park ,  Persefoni Kechagia ,  Michael Spaid ,  Morten Jensen ,  Irina Kazakova ,  Josh Molho ,  Tomohisa Kawabata ,  Mitsuo Watanabe

    IPC分类号： B01L3/00 ,  C12Q1/68 ,  G01N27/447 ,  G01N27/453

    CPC分类号： G01N27/44791 ,  B01L3/502715 ,  B01L3/502746 ,  B01L3/502753 ,  B01L3/502761 ,  B01L2200/0673 ,  B01L2400/0415 ,  C12Q1/6804 ,  C12Q1/6883 ,  G01N27/44773 ,  C12Q2565/629 ,  C12Q2565/125 ,  C12Q2563/179

    摘要： This invention provides methods and devices for spatially separating at least first and second components in a sample which in one exemplary embodiment comprises introducing the first and second components into a first microfluidic channel of a microfluidic device in a carrier fluid comprising a spacer electrolyte solution and stacking the first and second components by isotachophoresis between a leading electrolyte solution and a trailing electrolyte solution, wherein the spacer electrolyte solution comprises ions which have an intermediate mobility in an electric field between the mobility of the ions present in the leading and trailing electrolyte solutions and wherein the spacer electrolyte solution comprises at least one of the following spacer ions MOPS, MES, Nonanoic acid, D-Glucuronic acid, Acetylsalicyclic acid, 4-Ethoxybenzoic acid, Glutaric acid, 3-Phenylpropionic acid, Phenoxyacetic acid, Cysteine, hippuric acid, p-hydroxyphenylacetic acid, isopropylmalonic acid, itaconic acid, citraconic acid, 3,5-dimethylbenzoic acid, 2,3-dimethylbenzoic acid, p-hydroxycinnamic acid, and 5-br-2,4-dihydroxybenzoic acid, and wherein the first component comprises a DNA-antibody conjugate and the second component comprises a complex of the DNA-antibody conjugate and an analyte.

    摘要翻译： 本发明提供了用于空间分离样品中的至少第一和第二组分的方法和装置，其在一个示例性实施方案中包括将第一和第二组分引入载体流体中的微流体装置的第一微流体通道，所述载体流体包括间隔电解质溶液和层叠 所述第一和第二组分通过在前导电解质溶液和尾部电解质溶液之间的等速电泳，其中所述间隔电解质溶液包含在电场中具有中间迁移率的离子，所述离子存在于所述前导和后续电解质溶​​液中的离子的迁移率之间， 间隔电解质溶液包含以下间隔离子MOPS，MES，壬酸，D-葡糖醛酸，乙酰水杨酸，4-乙氧基苯甲酸，戊二酸，3-苯基丙酸，苯氧基乙酸，半胱氨酸，马尿酸，p 羟基苯乙酸，异丙基丙二酸，衣康酸a cid，柠康酸，3,5-二甲基苯甲酸，2,3-二甲基苯甲酸，对羟基肉桂酸和5-溴-2,4-二羟基苯甲酸，其中第一组分包含DNA-抗体缀合物，第二组分包含第二 组分包含DNA抗体缀合物和分析物的复合物。

    Method for modifying the concentration of reactants in a microfluidic device
    5.
    发明授权
    Method for modifying the concentration of reactants in a microfluidic device 有权
    用于改变微流体装置中反应物浓度的方法

    公开(公告)号：US08460530B2

    公开(公告)日：2013-06-11

    申请号：US13235318

    申请日：2011-09-16

    申请人： Charles Park ,  Irina Kazakova

    发明人： Charles Park ,  Irina Kazakova

    IPC分类号： G01N27/447 ,  G01N27/26

    CPC分类号： B01F5/0646 ,  B01F5/0647 ,  B01F13/0059 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2400/0421 ,  B01L2400/0487

    摘要： A method of modifying the concentration of reactants and carrying out a chemical reaction on a microfluidic device in which first and second reactants are delivered into a reaction channel combined, the second reactant different from the first reactant and capable of reacting with the first reactant. The first reactant is subjected to a stacking process, thereby producing a first stacked reactant. The second reactant is subjected to the stacking process, thereby producing a second stacked reactant. The first stacked reactant is exposed to the second stacked reactant so that the first stacked reactant and the second stacked reactant undergo a chemical reaction.

    摘要翻译： 一种改变反应物浓度并在微流体装置上进行化学反应的方法，其中第一和第二反应物被输送到组合的反应通道中，第二反应物不同于第一反应物并能够与第一反应物反应。 对第一反应物进行堆叠处理，从而产生第一层叠反应物。 第二反应物进行堆叠处理，从而产生第二堆叠反应物。 第一堆叠的反应物暴露于第二堆叠的反应物，使得第一堆叠的反应物和第二堆叠的反应物经历化学反应。

    Method and system for transporting data content on a storage area network
    8.
    发明申请
    Method and system for transporting data content on a storage area network 有权
    用于在存储区域网络上传送数据内容的方法和系统

    公开(公告)号：US20050004979A1

    公开(公告)日：2005-01-06

    申请号：US10903278

    申请日：2004-07-30

    申请人： Brian Berkowitz ,  Catherine van Ingen ,  Charles Park ,  Norbert Kusters

    发明人： Brian Berkowitz ,  Catherine van Ingen ,  Charles Park ,  Norbert Kusters

    IPC分类号： G06F3/06 ,  G06F12/00 ,  G06F15/16

    CPC分类号： G06F3/0601 ,  G06F11/2038 ,  G06F11/2097 ,  G06F2003/0697

    摘要： A system and method of transporting volumes of information from one host computer system to another using point-in-time copies of LUNs but wherein the hardware provider does not necessarily understand the volume configuration of the data. The system and method involves an intermediate layer, i.e., a point-in-time copy interface layer that communicates with both a requesting host computer system and a hardware provider to enable the transfer of volumes of information without requiring that the hardware provider understand the volume information.

    摘要翻译： 使用LUN的时间点副本将信息量从一台主机系统传输到另一台主机系统的系统和方法，但其中硬件提供商不一定了解数据的卷配置。 该系统和方法涉及中间层，即时间点复制界面层，其与请求主机计算机系统和硬件提供商通信，以便能够传输信息量，而不需要硬件提供商了解卷 信息。

    Method and System for Transporting Data Content on a Storage Area Network
    9.
    发明申请
    Method and System for Transporting Data Content on a Storage Area Network 有权
    用于在存储区域网络上传输数据内容的方法和系统

    公开(公告)号：US20070283111A1

    公开(公告)日：2007-12-06

    申请号：US11768816

    申请日：2007-06-26

    申请人： Brian Berkowitz ,  Catharine van Ingen ,  Charles Park ,  Norbert Kusters

    发明人： Brian Berkowitz ,  Catharine van Ingen ,  Charles Park ,  Norbert Kusters

    IPC分类号： G06F12/16

    CPC分类号： G06F3/0601 ,  G06F11/2038 ,  G06F11/2097 ,  G06F2003/0697

    摘要： A system and method of transporting volumes of information from one host computer system to another using point-in-time copies of LUNs but wherein the hardware provider does not necessarily understand the volume configuration of the data. The system and method involves an intermediate layer, i.e., a point-in-time copy interface layer that communicates with both a requesting host computer system and a hardware provider to enable the transfer of volumes of information without requiring that the hardware provider understand the volume information.

    摘要翻译： 使用LUN的时间点副本将信息量从一台主机系统传输到另一台主机系统的系统和方法，但其中硬件提供商不一定了解数据的卷配置。 该系统和方法涉及中间层，即时间点复制界面层，其与请求主机计算机系统和硬件提供商通信，以便能够传输信息量，而不需要硬件提供商了解卷 信息。

    Method of manufacturing and disk drive produced by measuring the read and write widths and varying the track pitch in the servo-writer
    10.
    发明申请
    Method of manufacturing and disk drive produced by measuring the read and write widths and varying the track pitch in the servo-writer 失效
    通过测量读写宽度并改变伺服写入器中的磁道间距而制造和制造磁盘驱动器的方法

    公开(公告)号：US20050117240A1

    公开(公告)日：2005-06-02

    申请号：US10978644

    申请日：2004-11-01

    申请人： Raffi Codilian ,  William Johns ,  Charles Park ,  David Nguyen ,  Jack Chue

    发明人： Raffi Codilian ,  William Johns ,  Charles Park ,  David Nguyen ,  Jack Chue

    IPC分类号： G11B5/596 ,  G11B21/02 ,  G11B27/36 ,  H04R31/00

    CPC分类号： G11B5/59633 ,  G11B5/59638 ,  Y10T29/49036

    摘要： A method of manufacturing a disk drive and a disk drive where the width of the read element and the width of the write element are both measured at servo-writing time and the track pitch of the disk drive is set on the basis of those measurements. Disk drives with superior head width combinations are servo-written with a narrower track pitch in order to have a higher storage capacity. Disk drives with inferior head width combinations are detected before servo-writing so that the disk drive may be servo-written with wider track pitch rather than with a nominal track pitch that results in a subsequent drive failure during initial burn-in (IBI). The heads are used more efficiently in that heads that are more capable are used to their ability and less capable heads that would otherwise be disposed of are used at all.

    摘要翻译： 基于这些测量，设置在伺服写入时刻测量读取元件的宽度和写入元件的宽度的盘驱动器和盘驱动器的方法，并且基于这些测量来设置磁盘驱动器的磁道间距。 具有优异头宽度组合的磁盘驱动器以较窄的磁道间距进行伺服写入，以具有更高的存储容量。 在伺服写入之前检测到具有较差头部宽度组合的磁盘驱动器，以便磁盘驱动器可以以更宽的磁道间距进行伺服写入，而不是在初始老化（IBI）期间导致后续驱动器故障的标称磁道间距。 头部被更有效地使用在那些使用能力更强的头部，否则将被处理的头部不太可用。