Systems, methods and devices for in vivo monitoring of a localized response via a radiolabeled analyte in a subject
    5.
    发明申请
    Systems, methods and devices for in vivo monitoring of a localized response via a radiolabeled analyte in a subject 审中-公开
    通过受试者中的放射性标记的分析物体内监测局部应答的系统,方法和装置

    公开(公告)号:US20050287065A1

    公开(公告)日:2005-12-29

    申请号:US11208983

    申请日:2005-08-22

    摘要: System for analyzing an in vivo response of a subject include a radiation detector for detecting radiation present in at least one localized solid tissue region of interest in a subject associated with internal activity of an administered quantity of an analyte comprising at least one of C-14 labeled glucose, a C-14 labeled constituent thereof, and a C-14 labeled glucose derivative, in the at least one solid tissue region of interest over a desired time interval of interest; and a reader in communication with the implantable detector for collecting radiation data from the detector associated with the detected radiation to determine at least one of the following; the in vivo dynamic, kinetic, and metabolic response of the subject.

    摘要翻译: 用于分析受试者的体内反应的系统包括用于检测存在于受试者中的至少一个局部固定组织感兴趣区域中的辐射的辐射检测器,其与施用量的分析物的内部活性相关,所述分析物包含C-14 标记的葡萄糖,其C-14标记的组分和C-14标记的葡萄糖衍生物,在目标的所需时间间隔内的至少一个实体组织区域中; 以及与所述可植入检测器通信的读取器,用于从与所述检测到的辐射相关联的所述检测器收集辐射数据,以确定以下中的至少一个; 受试者的体内动态,动力学和代谢反应。