-
1.发明申请Fused tricyclic heterocycles useful for treating hyper-proliferative disorders 失效用于治疗高增殖性疾病的融合的三环杂环公开(公告)号：US20060287387A1
公开(公告)日：2006-12-21
申请号：US11512032
申请日：2006-08-28
申请人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott Wilhelm , Qian Zhao
发明人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott Wilhelm , Qian Zhao
IPC分类号： A61K31/381 , A61K31/343
CPC分类号： C07D407/06 , C07D307/92 , C07D307/93 , C07D333/74 , C07D405/06 , C07D409/06 , C07D413/06 , C07D491/04 , C07D493/04
摘要： This invention relates to a novel fused tricyclic heterocycle of the formula and its use for the treatment of hyper-proliferative disorders.
摘要翻译： 本发明涉及下式的新型稠合三环杂环及其用于治疗高增殖性疾病的用途。
-
2.发明申请Fused tricyclic heterocycles useful for treating hyper-proliferative disoroders 失效用于治疗超增殖解调器的融合的三环杂环公开(公告)号：US20050165042A1
公开(公告)日：2005-07-28
申请号：US10501690
申请日：2003-02-21
申请人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott Wilheim , Qian Zhao
发明人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott Wilheim , Qian Zhao
IPC分类号： A61K31/343 , A61K31/381 , A61K31/4741 , A61K31/4743 , C07D307/92 , C07D307/93 , C07D333/74 , C07D405/06 , C07D407/06 , C07D409/06 , C07D413/06 , C07D491/04 , C07D493/04
CPC分类号： C07D407/06 , C07D307/92 , C07D307/93 , C07D333/74 , C07D405/06 , C07D409/06 , C07D413/06 , C07D491/04 , C07D493/04
摘要： This invention relates to a novel fused tricyclic heterocycle of the formula (Ia, Ib) and its use for the treatment of hyper-proliferative disorders.
摘要翻译： 本发明涉及式（Ia，Ib）的新型稠合三环杂环及其用于治疗高增殖性疾病的用途。
-
3.发明授权Fused tricyclic heterocycles useful for treating hyper-proliferative disorders 失效用于治疗高增殖性疾病的融合的三环杂环公开(公告)号：US07384947B2
公开(公告)日：2008-06-10
申请号：US11512032
申请日：2006-08-28
申请人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott M. Wilhelm , Qian Zhao
发明人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott M. Wilhelm , Qian Zhao
IPC分类号： A61K31/497 , A61K31/4355 , A61K31/4436 , A61K31/443 , A61K31/427
CPC分类号： C07D407/06 , C07D307/92 , C07D307/93 , C07D333/74 , C07D405/06 , C07D409/06 , C07D413/06 , C07D491/04 , C07D493/04
摘要： This invention relates to a novel fused tricyclic heterocycle of the formula and its use for the treatment of hyper-proliferative disorders.
摘要翻译： 本发明涉及下式的新型稠合三环杂环及其用于治疗高增殖性疾病的用途。
-
4.发明授权Fused tricyclic heterocycles useful for treating hyper-proliferative disorders 失效用于治疗高增殖性疾病的融合的三环杂环公开(公告)号：US07144885B2
公开(公告)日：2006-12-05
申请号：US10501690
申请日：2003-02-21
申请人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott M. Wilhelm , Qian Zhao
发明人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips , Scott M. Wilhelm , Qian Zhao
IPC分类号： A61K31/497 , A61K31/4355 , A61K31/4436 , A61K31/443 , A61K31/427
CPC分类号： C07D407/06 , C07D307/92 , C07D307/93 , C07D333/74 , C07D405/06 , C07D409/06 , C07D413/06 , C07D491/04 , C07D493/04
摘要： This invention relates to a novel fused tricyclic heterocycle of the formula (Ia, Ib) and its use for the treatment of hyper-proliferative disorders
摘要翻译： 本发明涉及式（Ia，Ib）的新型稠合三环杂环及其用于治疗高增殖性疾病的用途
-
5.发明授权Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders 失效苯并呋喃和苯并噻吩衍生物可用于治疗高增殖性疾病公开(公告)号：US07351735B2
公开(公告)日：2008-04-01
申请号：US10501689
申请日：2003-02-21
申请人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Jianmei Fan , Holia Hatoum-Mokdad , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips
发明人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Jianmei Fan , Holia Hatoum-Mokdad , Benjamin D. Jones , Gaetan Ladouceur , Wendy Lee , Barton Phillips
IPC分类号： A61K31/343 , A61K31/381 , C07D307/80 , C07D333/56
CPC分类号： C07D307/82 , C07D307/92 , C07D307/93 , C07D333/66 , C07D333/74 , C07D333/78 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/14 , C07D407/06 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D493/04
摘要： This invention relates to novel benzofuran and benzothiophene derivatives of the general table formula and their use for the treatment of hyper-proliferative disorders
摘要翻译： 本发明涉及一般表配方的新型苯并呋喃和苯并噻吩衍生物及其用于治疗高增殖性疾病的用途
-
6.发明申请Benzofuran and benzothiophene derivatives useful in the treatmint of hyper-proliferative disorders 失效苯并呋喃和苯并噻吩衍生物可用于高增殖性疾病的治疗公开(公告)号：US20050139814A1
公开(公告)日：2005-06-30
申请号：US10501689
申请日：2003-02-21
申请人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Jianmei Fan , Holia Hatoum-Mokdad , Benjamin Jones , Gaetan Ladouceur , Wendy Lee , Barton Philiips
发明人： Chengzhi Zhang , Michael Burke , Zhi Chen , Jacques Dumas , Dongping Fan , Jianmei Fan , Holia Hatoum-Mokdad , Benjamin Jones , Gaetan Ladouceur , Wendy Lee , Barton Philiips
IPC分类号： A61K31/343 , A61K31/353 , A61K31/357 , A61K31/36 , A61K31/381 , A61K31/422 , A61K31/427 , A61K31/4355 , A61K31/443 , A61K31/4436 , A61K31/455 , A61K31/497 , A61P13/08 , A61P13/10 , A61P35/00 , A61P35/02 , A61P35/04 , B66F3/36 , C07D307/82 , C07D307/92 , C07D307/93 , C07D333/66 , C07D333/74 , C07D333/78 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/14 , C07D407/06 , C07D409/04 , C07D409/06 , C07D409/14 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D491/048 , C07D493/04
CPC分类号： C07D307/82 , C07D307/92 , C07D307/93 , C07D333/66 , C07D333/74 , C07D333/78 , C07D405/04 , C07D405/06 , C07D405/10 , C07D405/14 , C07D407/06 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/06 , C07D417/04 , C07D417/06 , C07D493/04
摘要： This invention relates to novel benzofuran and benzothiophene derivatives of the general table formula and their use for the treatment of hyper-proliferative disorders.
摘要翻译： 本发明涉及通用表配方的新型苯并呋喃和苯并噻吩衍生物及其用于治疗高增殖性疾病的用途。
-
7.发明授权公开(公告)号：US07659412B2
公开(公告)日：2010-02-09
申请号：US12201547
申请日：2008-08-29
申请人： Chengzhi Zhang , Jacques Dumas , Gaetan Ladouceur , Qian Zhao , Martin Hentemann , Sharad Verma , Qingming Zhu , Rico Lavoie , Jianmei Fan , Barton Phillips
发明人： Chengzhi Zhang , Jacques Dumas , Gaetan Ladouceur , Qian Zhao , Martin Hentemann , Sharad Verma , Qingming Zhu , Rico Lavoie , Jianmei Fan , Barton Phillips
IPC分类号： C07D307/87 , A61K31/34
CPC分类号： C07D307/83 , C07D307/80 , C07D307/81 , C07D307/82 , C07D405/04
摘要： The invention relates to novel benzofuran derivatives, processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
摘要翻译： 本发明涉及新的苯并呋喃衍生物，其制备方法及其用于制备用于治疗或预防病症，特别是过度增殖性疾病的药物的用途。
-
8.发明申请Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders 失效用于治疗高增殖性疾病的取代的四氢苯并噻吩并嘧啶胺化合物公开(公告)号：US20060293322A1
公开(公告)日：2006-12-28
申请号：US10557090
申请日：2004-07-23
申请人： Chengzhi Zhang , Gaetan Ladouceur , Catherine Brennan , Brent Chandler , Julie Dizon , Karl Miranda , Dongping Fan , Qingming Zhu , Sharad Verma , Jacques Dumas
发明人： Chengzhi Zhang , Gaetan Ladouceur , Catherine Brennan , Brent Chandler , Julie Dizon , Karl Miranda , Dongping Fan , Qingming Zhu , Sharad Verma , Jacques Dumas
IPC分类号： A61K31/5377 , A61K31/519 , C07D498/02
CPC分类号： C07D495/04 , C07D498/02
摘要： The present invention relates to a compound of Formula (I) and its use in treating hyper-proliferative disorders.
摘要翻译： 本发明涉及式（I）化合物及其在治疗高增殖性疾病中的用途。
-
9.发明授权Pyrimidinothienoindazoles useful for the treatment of hyperproliferative disorders 失效嘧啶噻吩并吲唑可用于治疗过度增殖性疾病公开(公告)号：US08207172B2
公开(公告)日：2012-06-26
申请号：US11662416
申请日：2005-08-19
申请人： Chengzhi Zhang , Jacques Dumas , Qingming Zhu , Roger Smith , Qingjie Liu , Sharad Verma , Jason Duquette , Qian Zhao , Dongping Fan , Georgiy Bondar , Philip Coish
发明人： Chengzhi Zhang , Jacques Dumas , Qingming Zhu , Roger Smith , Qingjie Liu , Sharad Verma , Jason Duquette , Qian Zhao , Dongping Fan , Georgiy Bondar , Philip Coish
IPC分类号： C07D471/04
CPC分类号： C07D495/04 , C07D495/14
摘要： The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
摘要翻译： 本发明涉及式（I）的新型杂环，其制备方法及其用于制备用于治疗或预防病症，特别是过度增殖性疾病的药物的用途。
-
公开(公告)号：US20080132497A1
公开(公告)日：2008-06-05
申请号：US11665313
申请日：2005-10-14
申请人： Chengzhi Zhang , Roger Smith , Jason Duquette , Qian Zhao , Jacques Dumas , Georgiy Bondar , Yingfu Li , Dongping Fan
发明人： Chengzhi Zhang , Roger Smith , Jason Duquette , Qian Zhao , Jacques Dumas , Georgiy Bondar , Yingfu Li , Dongping Fan
IPC分类号： A61K31/541 , C07D239/70 , C07D295/00 , A61K31/519 , A61P35/00 , A61K31/5377 , A61K31/496
CPC分类号： C07D495/04
摘要： This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly hyperproliferative diseases such as cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly hyperproliferative diseases such as cancer.
摘要翻译： 本发明涉及新化合物及其制备方法，治疗疾病，特别是过度增殖性疾病如癌症的方法，包括给药所述化合物，以及制备用于治疗或预防病症，特别是过度增殖性疾病如癌症的药物组合物的方法。
-
-
-
-
-
-
-
-
-
搜索结果
100 条记录 (耗时 0.056 秒)
