Method and system for measuring an ultrashort optical pulse
    1.
    发明授权
    Method and system for measuring an ultrashort optical pulse 有权
    用于测量超短光脉冲的方法和系统

    公开(公告)号:US06734976B2

    公开(公告)日:2004-05-11

    申请号:US10096682

    申请日:2002-03-14

    IPC分类号: G01B902

    CPC分类号: G01J11/00

    摘要: A method for measuring an ultrashort optical pulse, in which third order autocorrelation of femtosecond (10−15 second) optical pulses was realized based on third-harmonic-generation (THG). A THG signal with three fundamental frequency photon contributed from three different split pulses of the ultrashort optical pulse is first generated. The three split pulses have time delays &tgr;1 and &tgr;2 in between. Then, the intensity of the THG signal is detected while varying the time delays &tgr;1 and &tgr;2 between the split pulses to obtain a triple correlation of the ultrashort optical pulse. The triple correlation and its Fourier transform are used to obtain the magnitude |Ĩ(&ngr;)| and the phase &agr;(&ngr;) of the ultrashort optical pulse intensity in the frequency domain, and the intensity of the ultrashort optical pulse in the time domain I(t) is determined using the magnitude |Ĩ(&ngr;)| and the phase &agr;(&ngr;) by inverse Fourier Transform.

    摘要翻译: 一种用于测量超短光脉冲的方法,其中基于三次谐波发生(THG)实现飞秒(10-15秒)光脉冲的三阶自相关。 首先产生由超短光脉冲的三个不同分离脉冲贡献的具有三个基频光子的THG信号。 三个分离脉冲之间具有时间延迟τ1和τ2。 然后,检测THG信号的强度,同时改变分离脉冲之间的时间延迟τ1和τ2,以获得超短光脉冲的三重相关。 三次相关及其傅里叶变换用于获得幅度| I(nu)| 并且在频域中的超短光脉冲强度的相位α(nu)和时域I(t)中的超短光脉冲的强度使用幅度| I(nu)| 和相位α(nu)。

    DETECT AND IDENTIFY VIRUS BY THE MICROWAVE ABSORPTION SPECTROSCOPY
    2.
    发明申请
    DETECT AND IDENTIFY VIRUS BY THE MICROWAVE ABSORPTION SPECTROSCOPY 有权
    通过微波吸收光谱检测和鉴定病毒

    公开(公告)号:US20090237067A1

    公开(公告)日:2009-09-24

    申请号:US12050894

    申请日:2008-03-18

    IPC分类号: G01N27/00 C12Q1/70

    CPC分类号: G01N22/00

    摘要: The present invention discloses microwave resonant absorption (MRA) of viruses through dipolar coupling to viral confined acoustic modes. The unique geometrical and mechanical properties of viruses can be reflected by the MRA frequencies, MRA linewidth, and the absorption selection rules of high-order acoustic modes. Combined these spectral characteristics with the mature microwave technology, this invention provides a novel physical mechanism to develop non-affinity-based rapid detection and identification of viruses. It can be applied in preliminary characterization on unknown or mutant viruses.

    摘要翻译: 本发明公开了通过偶极耦合到病毒封闭声学模式的病毒的微波共振吸收(MRA)。 病毒的独特几何和机械性质可以通过MRA频率,MRA线宽和高阶声学模式的吸收选择规则来反映。 将这些光谱特征与成熟的微波技术结合起来,本发明提供了开发基于非亲和性的快速检测和鉴定病毒的新型物理机制。 它可以应用于未知或突变病毒的初步表征。

    Detect and identify virus by the microwave absorption spectroscopy
    3.
    发明授权
    Detect and identify virus by the microwave absorption spectroscopy 有权
    通过微波吸收光谱检测和鉴定病毒

    公开(公告)号:US08524445B2

    公开(公告)日:2013-09-03

    申请号:US12050894

    申请日:2008-03-18

    IPC分类号: C12Q1/70 G01N27/00

    CPC分类号: G01N22/00

    摘要: The present invention discloses microwave resonant absorption (MRA) of viruses through dipolar coupling to viral confined acoustic modes. The unique geometrical and mechanical properties of viruses can be reflected by the MRA frequencies, MRA linewidth, and the absorption selection rules of high-order acoustic modes. Combined these spectral characteristics with the mature microwave technology, this invention provides a novel physical mechanism to develop non-affinity-based rapid detection and identification of viruses. It can be applied in preliminary characterization on unknown or mutant viruses.

    摘要翻译: 本发明公开了通过偶极耦合到病毒封闭声学模式的病毒的微波共振吸收(MRA)。 病毒的独特几何和机械性质可以通过MRA频率,MRA线宽和高阶声学模式的吸收选择规则来反映。 将这些光谱特征与成熟的微波技术结合起来,本发明提供了开发基于非亲和性的快速检测和鉴定病毒的新型物理机制。 它可以应用于未知或突变病毒的初步表征。

    Vacuum-pump sucker
    5.
    发明授权

    公开(公告)号:US09795340B2

    公开(公告)日:2017-10-24

    申请号:US12966218

    申请日:2010-12-13

    IPC分类号: A61B5/00

    摘要: This invention relates to a vacuum-pump sucker for high-resolution microscopy comprising a sucker body and a transparent plate. The vacuum-pump sucker is designed as a stabilizer for sample stabilization in a clinical optical virtual biopsy system with sub-micron resolution. The sucker is connected with a vacuum pump. As the vacuum pump pumps out air or gas, tissues around the imaged area will be sucked by the sucker and the distance between objective lens and the imaged tissue can be stabilized. In this way, the stability and resolution of the clinical biopsy system can be greatly improved.

    WAVEGUIDE HAVING A CLADDED CORE FOR GUIDING TERAHERTZ WAVES
    6.
    发明申请
    WAVEGUIDE HAVING A CLADDED CORE FOR GUIDING TERAHERTZ WAVES 审中-公开
    具有用于引导TERAHERTZ波形的梯形芯的波形图

    公开(公告)号:US20100135626A1

    公开(公告)日:2010-06-03

    申请号:US12536072

    申请日:2009-08-05

    IPC分类号: G02B6/02

    CPC分类号: H01P3/16

    摘要: A waveguide for guiding terahertz waves with wavelength ranging 0.1 mm-3 mm, includes a cladding tube made of a metal-free dielectric material, and a core filling a transmission space defined by the cladding tube. The core has a minimum width or diameter larger than the wavelength of the terahertz wave guided by the waveguide. The thickness of the cladding tube is smaller than the radius or one half of the width of the core. The core has an attenuation constant for the terahertz waves lower than that of the cladding tube. The waveguide guides terahertz waves mainly inside the core, and has a simple construction.

    摘要翻译: 用于引导波长为0.1mm-3mm的太赫兹波的波导包括由无金属介电材料制成的包覆管,以及填充由包层管限定的透射空间的芯。 芯的最小宽度或直径大于由波导引导的太赫波的波长。 包层管的厚度小于芯的宽度的半径或一半。 核心具有比包层管低的太赫兹波的衰减常数。 波导主要在核心内引导太赫兹波,结构简单。

    Harmonic generation microscopy
    7.
    发明授权

    公开(公告)号:US06922279B2

    公开(公告)日:2005-07-26

    申请号:US10665443

    申请日:2003-09-20

    摘要: A harmonic generation microscopy employs a laser device that emits a laser beam having a predetermined wavelength that causes no autofluorescence in a biological sample and that, after excited, induces both the second and third harmonic waves. The laser beam is projected onto a sample and an observation beam from the sample is received. The observation beam is directed through a splitter to separate the second harmonic wave and the third harmonic wave both of which are then converted into corresponding electrical signals. The electrical signals are fed to a computer-based image processing equipment to form an image of the sample on the basis of the second and third harmonic waves.

    Plural third harmonic generation microscopic system and method
    8.
    发明授权
    Plural third harmonic generation microscopic system and method 有权
    多次三次谐波生成微观系统及方法

    公开(公告)号:US08941087B2

    公开(公告)日:2015-01-27

    申请号:US13170518

    申请日:2011-06-28

    IPC分类号: G01N21/86 G01V8/00 G02B21/00

    摘要: The present invention provides a plural third harmonic generation (THG) microscopic system and method. The system includes a laser device, a microscopic device, a beam splitter device and a photodetective device. By utilizing lasers with different central wavelengths or a broad band light source to simultaneously analyze THG response with respect to different wavelengths, a plurality of THG images and THG spectrum of the material or bio-tissue under stimulation of different wavelengths are obtained, thereby retrieving distributed microscopic images and resonant characteristics of the observational material or bio-molecules.

    摘要翻译: 本发明提供一种三次谐波生成(THG)微观系统和方法。 该系统包括激光装置,微型装置,分束器装置和光电检测装置。 通过利用具有不同中心波长的激光器或宽带光源来同时分析相对于不同波长的THG响应,获得在不同波长刺激下的材料或生物组织的多个THG图像和THG光谱,从而检索分布 观察材料或生物分子的微观图像和共振特征。

    Plastic waveguide for terahertz wave

    公开(公告)号:US07409132B2

    公开(公告)日:2008-08-05

    申请号:US11493766

    申请日:2006-07-27

    IPC分类号: G02B6/02

    摘要: The invention discloses a plastic waveguide for guiding terahertz (THz) wave with a wavelength ranging from 30 to 3000 μm. The plastic waveguide includes a core and a cladding layer. At least part of the core is made of a first plastic medium having a first refractive index, and the maximum length of a cross-section of the core is smaller than the wavelength of the guided terahertz wave. The cladding layer surrounds the core and has a second refractive index lower than the first refractive index. In the invention, only one wave mode is propagated in the plastic waveguide, and a first attenuation constant of the core for the guided terahertz wave is higher than a second attenuation constant of the cladding layer for the guided terahertz wave.