SUBSTRATE MANUFACTURING METHOD FOR SENSOR APPLICATIONS USING OPTICAL CHARACTERISTICS AND THE SUBSTRATE THEREFROM
    2.
    发明申请
    SUBSTRATE MANUFACTURING METHOD FOR SENSOR APPLICATIONS USING OPTICAL CHARACTERISTICS AND THE SUBSTRATE THEREFROM 有权
    使用光学特性和基板的传感器应用的基板制造方法

    公开(公告)号:US20100239464A1

    公开(公告)日:2010-09-23

    申请号:US12741389

    申请日:2008-10-23

    摘要: A method for manufacturing a substrate of an analytical sensor and the substrate thus prepared are disclosed. The method for manufacturing the substrate of the sensor application according to the present invention is characterized in that it comprises (a) the step of preparing a dispersed solution of nanoparticles, which are stable in a volatile organic solvent due to surface modification of nanoparticles having a pre-designed certain size on the nanometer level with an organic functional group (b) the step of preparing a single layer film of nanoparticles surface-modified with the organic functional group on the interface using said dispersed solution of nanoparticles on the basis of the Langmuir-Blodgett method, and then transferring said single layer film of nanoparticles to the substrate; and (c) the step of coating the substrate to which said single layer film of nanoparticles is transferred, with the metal thin film by means of the vacuum vapor deposition, and then optionally removing nanoparticles to manufacture a nanostructure to be used as the analytical sensor using optical characteristics. According to the method for manufacturing the substrate of the sensor application according to the present invention as above, the nanoparticles can be uniformly fixed on the solid substrate having a great area above 10×10 cm2 using the Langmuir-Blodgett method, and by such method the size, distance and shape of nanoparticles can be controlled to manufacture the nanostructures to be used as the analytical sensor, which is possible to reproduce and mass-produce. When the sensitivity property of the sensor is measured using the nanostructure substrate, thus produced, to be used as the analytical sensor, it can be identified that the sensitivity can be highly improved.

    摘要翻译: 公开了一种用于制造如此制备的分析传感器和衬底的衬底的方法。 根据本发明的传感器应用的基板的制造方法的特征在于,其包括(a)制备纳米颗粒的分散溶液的步骤,所述分散溶液由于纳米颗粒的表面改性而在挥发性有机溶剂中稳定, 用有机官能团预先设计在纳米级上的一定尺寸(b)制备在界面上用有机官能团表面改性的纳米颗粒单层薄膜的步骤,该纳米粒子基于Langmuir -Blodgett方法,然后将所述单层纳米颗粒膜转移到基底; 和(c)通过真空气相沉积用金属薄膜涂覆纳米颗粒的单层膜转移到其上的基底的步骤,然后任选地除去纳米颗粒以制造用作分析传感器的纳米结构 使用光学特性。 根据如上所述的根据本发明的传感器应用的基板的制造方法,可以使用Langmuir-Blodgett方法将纳米颗粒均匀地固定在具有大于10×10cm 2的大面积的固体基板上,并且通过这种方法 可以控制纳米颗粒的尺寸,距离和形状,以制造用作分析传感器的纳米结构,其可以再现和批量生产。 当使用由此产生的纳米结构基板测量传感器的灵敏度特性作为分析传感器时,可以确定可以高度提高灵敏度。

    Substrate manufacturing method for sensor applications using optical characteristics and the substrate therefrom
    3.
    发明授权
    Substrate manufacturing method for sensor applications using optical characteristics and the substrate therefrom 有权
    使用光学特性的传感器应用的基板制造方法及其基板

    公开(公告)号:US08414965B2

    公开(公告)日:2013-04-09

    申请号:US12741389

    申请日:2008-10-23

    摘要: A method for manufacturing a substrate of an analytical sensor and the substrate thus prepared are disclosed. The method for manufacturing the substrate of the sensor application according to the present invention is characterized in that it comprises (a) the step of preparing a dispersed solution of nanoparticles, which are stable in a volatile organic solvent due to surface modification of nanoparticles having a pre-designed certain size on the nanometer level with an organic functional group (b) the step of preparing a single layer film of nanoparticles surface-modified with the organic functional group on the interface using said dispersed solution of nanoparticles on the basis of the Langmuir-Blodgett method, and then transferring said single layer film of nanoparticles to the substrate; and (c) the step of coating the substrate to which said single layer film of nanoparticles is transferred, with the metal thin film by means of the vacuum vapor deposition, and then optionally removing nanoparticles to manufacture a nanostructure to be used as the analytical sensor using optical characteristics. According to the method for manufacturing the substrate of the sensor application according to the present invention as above, the nanoparticles can be uniformly fixed on the solid substrate having a great area above 10×10 cm2 using the Langmuir-Blodgett method, and by such method the size, distance and shape of nanoparticles can be controlled to manufacture the nanostructures to be used as the analytical sensor, which is possible to reproduce and mass-produce. When the sensitivity property of the sensor is measured using the nanostructure substrate, thus produced, to be used as the analytical sensor, it can be identified that the sensitivity can be highly improved.

    摘要翻译: 公开了一种用于制造如此制备的分析传感器和衬底的衬底的方法。 根据本发明的传感器应用的基板的制造方法的特征在于,其包括(a)制备纳米颗粒的分散溶液的步骤,所述分散溶液由于纳米颗粒的表面改性而在挥发性有机溶剂中稳定, 用有机官能团预先设计在纳米级上的一定尺寸(b)制备在界面上用有机官能团表面改性的纳米颗粒单层薄膜的步骤,该纳米粒子基于Langmuir -Blodgett方法,然后将所述单层纳米颗粒膜转移到基底; 和(c)通过真空气相沉积用金属薄膜涂覆纳米颗粒的单层膜转移到其上的基底的步骤,然后任选地除去纳米颗粒以制造用作分析传感器的纳米结构 使用光学特性。 根据如上所述的根据本发明的传感器应用的基板的制造方法,可以使用Langmuir-Blodgett方法将纳米颗粒均匀地固定在具有大于10×10cm 2的大面积的固体基板上,并且通过这种方法 可以控制纳米颗粒的尺寸,距离和形状,以制造用作分析传感器的纳米结构,其可以再现和批量生产。 当使用由此产生的纳米结构基板测量传感器的灵敏度特性作为分析传感器时,可以确定可以高度提高灵敏度。

    PREPARATION METHOD OF ANTIGEN-IMMOBILIZED IMMUNO- FLUORESCENCE SLIDE AND IMMUNO-FLUOROSCENCE SLIDE PREPARED THEREBY
    4.
    发明申请
    PREPARATION METHOD OF ANTIGEN-IMMOBILIZED IMMUNO- FLUORESCENCE SLIDE AND IMMUNO-FLUOROSCENCE SLIDE PREPARED THEREBY 审中-公开
    抗原免疫荧光镜和免疫荧光镜的制备方法

    公开(公告)号:US20130029428A1

    公开(公告)日:2013-01-31

    申请号:US13261437

    申请日:2011-02-21

    IPC分类号: G01N21/64 C07K17/02 B82Y15/00

    CPC分类号: G01N33/54366

    摘要: A method of preparing an antigen-immobilized immuno-fluorescence slide, the method comprising: immobilizing a C-reactive protein on a slide to prepare a protein chip; mixing an antibody that specifically binds to a target protein, with streptavidin to label the antibody with a fluorescent nanoparticle; immuno-reacting the antibody by competitive mixing, assaying with a fluorescence camera, wherein the immobilizing of the C-reactive protein on the slide comprises: modifying the slide with 3-aminopropyltrimethoxysilane to prepare a modified slide; hydrating the slide modified with 3-aminopropyltrimethoxysilane; activating the modified slide by using a glutaraldehyde solution; dissolving a C-reactive protein at a concentration of 0.01-0.5 mg/ml in a 30-70 mM phosphate buffer solution (pH 6.5-7.8) to prepare an antigen solution for immobilization; placing a petri dish comprising the slide on a spotting guide and spotting 1-100 μl of the antigen solution on spotting points; and performing a reaction on the slide prepared as described above for 1-6 hours to immobilize the antigen, and an immune-fluorescence slide prepared by using the method.

    摘要翻译: 一种制备抗原固定化免疫荧光载片的方法,所述方法包括:将C反应蛋白固定在载玻片上以制备蛋白质芯片; 将特异性结合靶蛋白的抗体与链霉抗生物素蛋白混合以用荧光纳米颗粒标记抗体; 通过竞争性混合使抗体免疫反应,用荧光相机进行测定,其中将C-反应蛋白固定在载玻片上包括:用3-氨基丙基三甲氧基硅烷改性载玻片以制备修饰的载玻片; 水化用3-氨基丙基三甲氧基硅烷改性的载玻片; 通过使用戊二醛溶液活化修饰的载玻片; 在30-70mM磷酸盐缓冲溶液(pH6.5-7.8)中溶解浓度为0.01-0.5mg / ml的C-反应蛋白以制备用于固定的抗原溶液; 将包含载玻片的陪替氏培养皿置于点样引导物上,并在点样点上点样1-100μl的抗原溶液; 并对如上所述制备的载玻片进行1-6小时的反应以固定抗原,以及通过使用该方法制备的免疫荧光载片。

    Method and apparatus for inspecting flat panel display
    5.
    发明授权
    Method and apparatus for inspecting flat panel display 有权
    检查平板显示器的方法和装置

    公开(公告)号:US07301360B2

    公开(公告)日:2007-11-27

    申请号:US10669348

    申请日:2003-09-25

    IPC分类号: G01R31/00

    摘要: A novel method and apparatus inspects liquid crystal display. The method and apparatus for inspecting the flat display device scans at least one signal wire by using a magnetic sensor and detects a resistance change of the magnetic sensor to perceive a short in the signal wire. Pixels can be tested using an array of magnetic sensors configured such that each sensor in the array is smaller than the pixel.

    摘要翻译: 一种新颖的方法和装置检查液晶显示器。 用于检查平板显示装置的方法和装置通过使用磁传感器扫描至少一根信号线,并检测磁传感器的电阻变化以感知信号线中的短路。 可以使用配置为阵列中的每个传感器小于像素的磁性传感器阵列来测试像素。

    Method and apparatus for testing liquid crystal display device
    6.
    发明授权
    Method and apparatus for testing liquid crystal display device 有权
    液晶显示装置检测方法及装置

    公开(公告)号:US07358756B2

    公开(公告)日:2008-04-15

    申请号:US11391569

    申请日:2006-03-29

    IPC分类号: G01R31/00

    摘要: A method and apparatus for testing a liquid crystal display device are provided to detect a defect location precisely and rapidly without requiring a jig. The method includes providing an inspection apparatus as a removable portion of the liquid crystal display device; inspecting the display part of the liquid crystal display device using the inspection apparatus; removing the inspection apparatus from the liquid crystal display device after the inspection is completed; and attaching driving circuits to the liquid crystal display device having the inspection apparatus removed therefrom.

    摘要翻译: 提供了用于测试液晶显示装置的方法和装置,用于在不需要夹具的情况下精确而快速地检测缺陷位置。 该方法包括提供作为液晶显示装置的可移除部分的检查装置; 使用检查装置检查液晶显示装置的显示部分; 在检查完成之后,从液晶显示装置中取出检查装置; 并且将驱动电路附接到具有从其去除的检查装置的液晶显示装置。

    Method and apparatus for testing liquid crystal display device
    7.
    发明授权
    Method and apparatus for testing liquid crystal display device 有权
    液晶显示装置检测方法及装置

    公开(公告)号:US07046030B2

    公开(公告)日:2006-05-16

    申请号:US10669460

    申请日:2003-09-25

    IPC分类号: G01R31/00

    摘要: A method and apparatus for testing a liquid crystal display device are provided to detect a defect location precisely and rapidly without requiring a jig. The method includes providing a substrate to inspect, wherein the substrate includes signal wirings, drive switches and capacitors formed in an effective display area of the substrate; radiating a light onto an inspection switch device and thereby supplying an inspection voltage from an inspection line to one of the drive switches through the signal wirings, so as to charge one of the capacitors; and determining if there is a defect in the effective display area of the substrate by reading the charged voltage of the capacitor.

    摘要翻译: 提供了用于测试液晶显示装置的方法和装置,用于在不需要夹具的情况下精确而快速地检测缺陷位置。 该方法包括提供衬底以检查其中衬底包括形成在衬底的有效显示区域中的信号布线,驱动开关和电容器; 将光照射到检查开关装置上,从而通过信号布线将检查线路的检查电压提供给驱动开关之一,从而对电容器之一充电; 以及通过读取电容器的充电电压来确定衬底的有效显示区域中是否存在缺陷。

    METHOD AND APPARATUS FOR TESTING LIQUID CRYSTAL DISPLAY DEVICE
    8.
    发明申请
    METHOD AND APPARATUS FOR TESTING LIQUID CRYSTAL DISPLAY DEVICE 有权
    用于测试液晶显示器件的方法和装置

    公开(公告)号:US20080136440A1

    公开(公告)日:2008-06-12

    申请号:US12034422

    申请日:2008-02-20

    IPC分类号: G01R31/28 G02F1/133

    摘要: A method and apparatus for testing a liquid crystal display device are provided to detect a defect location precisely and rapidly without requiring a jig. The method includes providing an inspection apparatus as a removable portion of the liquid crystal display device; inspecting the display part of the liquid crystal display device using the inspection apparatus; removing the inspection apparatus from the liquid crystal display device after the inspection is completed; and attaching driving circuits to the liquid crystal display device having the inspection apparatus removed therefrom.

    摘要翻译: 提供了用于测试液晶显示装置的方法和装置,用于在不需要夹具的情况下精确而快速地检测缺陷位置。 该方法包括提供作为液晶显示装置的可移除部分的检查装置; 使用检查装置检查液晶显示装置的显示部分; 在检查完成之后,从液晶显示装置中取出检查装置; 并且将驱动电路附接到具有从其去除的检查装置的液晶显示装置。

    Method and apparatus for testing liquid crystal display using electrostatic devices
    9.
    发明授权
    Method and apparatus for testing liquid crystal display using electrostatic devices 有权
    使用静电装置测试液晶显示器的方法和装置

    公开(公告)号:US07362124B2

    公开(公告)日:2008-04-22

    申请号:US11541577

    申请日:2006-10-03

    IPC分类号: G01R31/00

    CPC分类号: G09G3/006

    摘要: A method and apparatus are provided for inspecting an electrical defectiveness of a liquid crystal display substrate. The method includes shorting ESD protection devices with a conductive shorting bar to form a current path on each of signal wirings of the substrate, supplying a current to the signal wirings, and determining a defectiveness of the signal wirings depending on the current flowing on the signal wirings.

    摘要翻译: 提供了一种用于检查液晶显示基板的电气缺陷性的方法和装置。 该方法包括用导电短路棒短路ESD保护装置,以在基板的每个信号布线上形成电流路径,向信号布线提供电流,以及根据在信号上流动的电流来确定信号布线的缺陷 布线。