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公开(公告)号：US07819826B2
公开(公告)日：2010-10-26
申请号：US10351450
申请日：2003-01-23
申请人： Chris J. Diederich , Jeffrey C. Lotz , Will Nau , David S. Bradford , John P. O'Banion , James C. Peacock, III
发明人： Chris J. Diederich , Jeffrey C. Lotz , Will Nau , David S. Bradford , John P. O'Banion , James C. Peacock, III
IPC分类号： A61B8/00
CPC分类号： A61B18/04 , A61B8/56 , A61B2017/00092 , A61B2017/00101 , A61B2017/00261 , A61B2018/00339 , A61B2090/374 , A61N7/00 , A61N7/02 , A61N7/022 , A61N2007/0078
摘要： A long-term implantable ultrasound therapy system and method is provided that provides directional, focused ultrasound to localized regions of tissue within body joints, such as spinal joints. An ultrasound emitter or transducer is delivered to a location within the body associated with the joint and heats the target region of tissue associated with the joint from the location. Such locations for ultrasound transducer placement may include for example in or around the intervertebral discs, or the bony structures such as vertebral bodies or posterior vertebral elements such as facet joints. Various modes of operation provide for selective, controlled heating at different temperature ranges to provide different intended results in the target tissue, which ranges are significantly effected by pre-stressed tissues such as in-vivo intervertebral discs. In particular, treatments above 70 degrees C., and in particular 75 degrees C., are used for structural remodeling, whereas lower temperatures achieves other responses without appreciable remodeling.
摘要翻译： 提供了一种长期植入式超声治疗系统和方法，其向身体关节内诸如脊椎关节之间的组织的局部区域提供定向的聚焦超声。 将超声发射器或换能器输送到与关节相关联的身体内的位置，并从该位置加热与关节相关联的组织的目标区域。 用于超声换能器放置的这种位置可以包括例如在椎间盘内或周围，或骨结构，例如椎体或后椎体元件，例如小关节。 各种操作模式提供在不同温度范围内的选择性控制加热，以在目标组织中提供不同的预期结果，这些范围通过诸如体内椎间盘的预应力组织显着影响。 特别地，高于70摄氏度，特别是75摄氏度的处理被用于结构重塑，而较低的温度实现了其他响应而没有明显的重塑。
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2.发明授权System and method providing directional ultrasound therapy to skeletal joints 有权向骨骼关节提供定向超声治疗的系统和方法公开(公告)号：US07211055B2
公开(公告)日：2007-05-01
申请号：US10347164
申请日：2003-01-15
IPC分类号： A61F7/00
CPC分类号： A61N7/02 , A61B18/04 , A61B2017/00092 , A61B2017/00101 , A61B2017/00261 , A61B2090/374 , A61N7/022 , A61N2007/0021 , A61N2007/003 , A61N2007/0056 , A61N2007/0078
摘要： An ultrasound therapy system and method is provided that provides directional, focused ultrasound to localized regions of tissue within body joints, such as spinal joints. An ultrasound emitter or transducer is delivered to a location within the body associated with the joint and heats the target region of tissue associated with the joint from the location. Such locations for ultrasound transducer placement may include for example in or around the intervertebral discs, or the bony structures such as vertebral bodies or posterior vertebral elements such as facet joints. Various modes of operation provide for selective, controlled heating at different temperature ranges to provide different intended results in the target tissue, which ranges are significantly effected by pre-stressed tissues such as in-vivo intervertebral discs. In particular, treatments above 70 degrees C., and in particular 75 degrees C., are used for structural remodeling, whereas lower temperatures achieves other responses without appreciable remodeling.
摘要翻译： 提供超声治疗系统和方法，其向身体关节内诸如脊椎关节之间的组织的局部区域提供定向的聚焦超声。 将超声发射器或换能器输送到与关节相关联的身体内的位置，并从该位置加热与关节相关联的组织的目标区域。 用于超声换能器放置的这种位置可以包括例如在椎间盘内或周围，或骨结构，例如椎体或后椎体元件，例如小关节。 各种操作模式提供在不同温度范围内的选择性控制加热，以在目标组织中提供不同的预期结果，这些范围通过诸如体内椎间盘的预应力组织显着影响。 特别地，高于70摄氏度，特别是75摄氏度的处理被用于结构重塑，而较低的温度实现了其他响应而没有明显的重塑。
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公开(公告)号：US08915949B2
公开(公告)日：2014-12-23
申请号：US12781689
申请日：2010-05-17
CPC分类号： A61N7/02 , A61B18/04 , A61B2017/00092 , A61B2017/00101 , A61B2017/00261 , A61B2090/374 , A61N7/022 , A61N2007/0021 , A61N2007/003 , A61N2007/0056 , A61N2007/0078
摘要： An ultrasound therapy system and method is provided that provides directional, focused ultrasound to localized regions of tissue within body joints, such as spinal joints. An ultrasound emitter or transducer is delivered to a location within the body associated with the joint and heats the target region of tissue associated with the joint from the location. Such locations for ultrasound transducer placement may include for example in or around the intervertebral discs, or the bony structures such as vertebral bodies or posterior vertebral elements such as facet joints. Various modes of operation provide for selective, controlled heating at different temperature ranges to provide different intended results in the target tissue, which ranges are significantly affected by pre-stressed tissues such as in-vivo intervertebral discs. In particular, treatments above 70 degrees C., and in particular 75 degrees C., are used for structural remodeling, whereas lower temperatures achieve other responses without appreciable remodeling.
摘要翻译： 提供超声治疗系统和方法，其向身体关节内诸如脊椎关节之间的组织的局部区域提供定向的聚焦超声。 将超声发射器或换能器输送到与关节相关联的身体内的位置，并从该位置加热与关节相关联的组织的目标区域。 用于超声换能器放置的这种位置可以包括例如在椎间盘内或周围，或骨结构，例如椎体或后椎体元件，例如小关节。 各种操作模式提供在不同温度范围内的选择性控制加热，以在目标组织中提供不同的预期结果，该范围受到诸如体内椎间盘之类的预应力组织的显着影响。 特别地，高于70摄氏度，特别是75摄氏度的处理被用于结构重塑，而较低的温度实现其他响应而没有明显的重塑。
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公开(公告)号：US20110022133A1
公开(公告)日：2011-01-27
申请号：US12781689
申请日：2010-05-17
IPC分类号： A61F7/00
CPC分类号： A61N7/02 , A61B18/04 , A61B2017/00092 , A61B2017/00101 , A61B2017/00261 , A61B2090/374 , A61N7/022 , A61N2007/0021 , A61N2007/003 , A61N2007/0056 , A61N2007/0078
摘要： An ultrasound therapy system and method is provided that provides directional, focused ultrasound to localized regions of tissue within body joints, such as spinal joints. An ultrasound emitter or transducer is delivered to a location within the body associated with the joint and heats the target region of tissue associated with the joint from the location. Such locations for ultrasound transducer placement may include for example in or around the intervertebral discs, or the bony structures such as vertebral bodies or posterior vertebral elements such as facet joints. Various modes of operation provide for selective, controlled heating at different temperature ranges to provide different intended results in the target tissue, which ranges are significantly affected by pre-stressed tissues such as in-vivo intervertebral discs. In particular, treatments above 70 degrees C., and in particular 75 degrees C., are used for structural remodeling, whereas lower temperatures achieve other responses without appreciable remodeling.
摘要翻译： 提供超声治疗系统和方法，其向身体关节内诸如脊椎关节之间的组织的局部区域提供定向的聚焦超声。 将超声发射器或换能器输送到与关节相关联的身体内的位置，并从该位置加热与关节相关联的组织的目标区域。 用于超声换能器放置的这种位置可以包括例如在椎间盘内或周围，或骨结构，例如椎体或后椎体元件，例如小关节。 各种操作模式提供在不同温度范围内的选择性控制加热，以在目标组织中提供不同的预期结果，该范围受到诸如体内椎间盘之类的预应力组织的显着影响。 特别地，高于70摄氏度，特别是75摄氏度的处理被用于结构重塑，而较低的温度实现其他响应而没有明显的重塑。
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5.发明授权Method of thermal treatment of myolysis and destruction of benign uterine tumors 有权热解治疗良性子宫肿瘤的解离和破坏的方法公开(公告)号：US08790281B2
公开(公告)日：2014-07-29
申请号：US11738391
申请日：2007-04-20
CPC分类号： A61N7/022 , A61B17/2202 , A61B2017/4216 , A61N5/045 , A61N7/02 , A61N2005/1094 , A61N2007/0004 , A61N2007/0078
摘要： A high-power ultrasound heating applicator for minimally-invasive thermal treatment of uterine fibroids or myomas. High-intensity interstitial ultrasound, applied with minimally-invasive laparoscopic or hysteroscopic procedures, is used to effectively treat fibroids within the myometrium in lieu of major surgery. The applicators are configured with high-power capabilities and thermal penetration to treat large volumes of fibroid tissue (>70 cm3) in short treatment times (3-20 minutes), while maintaining three-dimensional control of energy delivery to thermally destroy the target volume.
摘要翻译： 一种用于子宫肌瘤或肌瘤的微创热治疗的大功率超声加热器。 高强度间质超声，应用微创腹腔镜或宫腔镜手术，用于有效治疗子宫肌层内的子宫肌瘤，代替大手术。 施用器配置有大功率能力和热穿透，以在短时间内（3-20分钟）处理大量的纤维组织（> 70厘米3），同时保持能量传递的三维控制以热破坏目标体积 。
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6.发明申请公开(公告)号：US20070255267A1
公开(公告)日：2007-11-01
申请号：US11738391
申请日：2007-04-20
申请人： Chris Diederich , Will Nau , Alison Jacoby , Dana Deardorff , Everette Burdette
发明人： Chris Diederich , Will Nau , Alison Jacoby , Dana Deardorff , Everette Burdette
IPC分类号： A61B18/04
CPC分类号： A61N7/022 , A61B17/2202 , A61B2017/4216 , A61N5/045 , A61N7/02 , A61N2005/1094 , A61N2007/0004 , A61N2007/0078
摘要： A high-power ultrasound heating applicator for minimally-invasive thermal treatment of uterine fibroids or myomas. High-intensity interstitial ultrasound, applied with minimally-invasive laparoscopic or hysteroscopic procedures, is used to effectively treat fibroids within the myometrium in lieu of major surgery. The applicators are configured with high-power capabilities and thermal penetration to treat large volumes of fibroid tissue (>70 cm3) in short treatment times (3-20 minutes), while maintaining three-dimensional control of energy delivery to thermally destroy the target volume.
摘要翻译： 一种用于子宫肌瘤或肌瘤的微创热治疗的大功率超声加热器。 高强度间质超声，应用微创腹腔镜或宫腔镜手术，用于有效治疗子宫肌层内的子宫肌瘤，代替大手术。 施用器配置有大功率能力和热穿透，以在短时间（3-20分钟）内处理大量的纤维组织（> 70cm 3以上），同时保持三维控制 能量传递以热破坏目标体积。
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7.发明申请System and method providing directional ultrasound therapy to skeletal joints 审中-公开向骨骼关节提供定向超声治疗的系统和方法公开(公告)号：US20060241576A1
公开(公告)日：2006-10-26
申请号：US11364357
申请日：2006-02-27
申请人： Chris Diederich , Jeffrey Lotz , Will Nau , David Bradford
发明人： Chris Diederich , Jeffrey Lotz , Will Nau , David Bradford
CPC分类号： A61N7/02 , A61B18/04 , A61B2017/00092 , A61B2017/00101 , A61B2017/00261 , A61B2090/374 , A61N7/022 , A61N2007/0021 , A61N2007/003 , A61N2007/0056 , A61N2007/0078
摘要： An ultrasound therapy system and method is provided that provides directional, focused ultrasound to localized regions of tissue within body joints, such as spinal joints. An ultrasound emitter or transducer is delivered to a location within the body associated with the joint and heats the target region of tissue associated with the joint from the location. Such locations for ultrasound transducer placement may include for example in or around the intervertebral discs, or the bony structures such as vertebral bodies or posterior vertebral elements such as facet joints. Various modes of operation provide for selective, controlled heating at different temperature ranges to provide different intended results in the target tissue, which ranges are significantly affected by pre-stressed tissues such as in-vivo intervertebral discs. In particular, treatments above 70 degrees C., and in particular 75 degrees C., are used for structural remodeling, whereas lower temperatures achieve other responses without appreciable remodeling.
摘要翻译： 提供超声治疗系统和方法，其向身体关节内诸如脊椎关节之间的组织的局部区域提供定向的聚焦超声。 将超声发射器或换能器输送到与关节相关联的身体内的位置，并从该位置加热与关节相关联的组织的目标区域。 用于超声换能器放置的这种位置可以包括例如在椎间盘内或周围，或骨结构，例如椎体或后椎体元件，例如小关节。 各种操作模式提供在不同温度范围内的选择性控制加热，以在目标组织中提供不同的预期结果，该范围受到诸如体内椎间盘之类的预应力组织的显着影响。 特别地，高于70摄氏度，特别是75摄氏度的处理被用于结构重塑，而较低的温度实现其他响应而没有明显的重塑。
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