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    Texturizing lactic bacteria
    6.
    发明授权
    Texturizing lactic bacteria 有权
    培养乳酸菌

    公开(公告)号：US07582743B2

    公开(公告)日：2009-09-01

    申请号：US10548940

    申请日：2004-03-12

    申请人： Philippe Horvath ,  Elise Manoury ,  Sonia Huppert ,  Christophe Fremaux

    发明人： Philippe Horvath ,  Elise Manoury ,  Sonia Huppert ,  Christophe Fremaux

    IPC分类号： C12N1/20 ,  C12N15/00 ,  C07H21/04

    CPC分类号： C12R1/46 ,  A23C9/1238 ,  A23Y2240/75 ,  C12N15/52 ,  C12P19/04

    摘要： The invention relates to a novel strain of lactic bacteria comprising at least one sequence selected from a group consisting of nucleotide sequences SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4, SEQ ID No. 5, SEQ ID No. 6, SEQ ID No. 7, SEQ ID No. 8 and to a method for the production of said strains. The invention also relates to the sequences SEQ ID Nos. 1-8 and to a nucleic acid, vectors and plasmids comprising said sequences. The invention further relates to food products, especially milk products containing said strains.

    摘要翻译： 本发明涉及一种新的乳酸菌菌株，其包含至少一种选自下组的序列：核苷酸序列SEQ ID No.1，SEQ ID No.2，SEQ ID No.3，SEQ ID No.4，SEQ ID No 5，SEQ ID No.6，SEQ ID No.7，SEQ ID No.8，以及生产所述菌株的方法。 本发明还涉及序列SEQ ID No.18和涉及包含所述序列的核酸，载体和质粒。 本发明还涉及食品，特别是含有所述菌株的奶制品。

    Cultures with Improved Phage Resistance
    8.
    发明申请
    Cultures with Improved Phage Resistance 审中-公开
    具有改进的抗药性的培养物

    公开(公告)号：US20110002889A1

    公开(公告)日：2011-01-06

    申请号：US12529421

    申请日：2008-02-29

    申请人： Rodolphe Barrangou ,  Christophe Fremaux ,  Philippe Horvath ,  Dennis Romero ,  Patrick Boyaval

    发明人： Rodolphe Barrangou ,  Christophe Fremaux ,  Philippe Horvath ,  Dennis Romero ,  Patrick Boyaval

    IPC分类号： A61K35/74 ,  C12N15/74 ,  C12N1/21 ,  A23L1/00 ,  A23C9/12

    摘要： The present invention provides methods and compositions related to modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some preferred embodiments, the present invention provides compositions and methods for the use of one or more cas genes or proteins for modulating the resistance of a cell against a target nucleic acid or a transcription product thereof. In some embodiments, the present invention provides methods and compositions that find use in the development and use of strain combinations and starter culture rotations. In additional embodiments, the present invention provides methods for labelling and/or identifying bacteria. In some preferred embodiments, the present invention provides methods for the use of CRISPR loci to determine the potential virulence of a phage against a cell and the use of CRISPR-cas to modulate the genetic sequence of a phage for increased virulence level. In still further embodiments, the present invention provides means and compositions for the development and use of phages as biocontrol agents.

    摘要翻译： 本发明提供了与调节细胞对靶核酸或其转录产物的抗性相关的方法和组合物。 在一些优选实施方案中，本发明提供了使用一种或多种cas基因或蛋白质调节细胞对靶核酸或其转录产物的抗性的组合物和方法。 在一些实施方案中，本发明提供了用于开发和使用菌株组合和起始培养旋转的方法和组合物。 在另外的实施方案中，本发明提供用于标记和/或鉴定细菌的方法。 在一些优选的实施方案中，本发明提供了使用CRISPR基因座确定噬菌体对细胞的潜在毒力的方法，以及使用CRISPR-cas调节噬菌体的遗传序列以增加毒力水平。 在另外的实施方案中，本发明提供用于开发和使用噬菌体作为生物防治剂的方法和组合物。