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    System and method for optical coherence imaging
    4.
    再颁专利
    System and method for optical coherence imaging 有权
    光学相干成像系统和方法

    公开(公告)号：USRE45512E1

    公开(公告)日：2015-05-12

    申请号：US13611926

    申请日：2012-09-12

    申请人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett E. Bouma

    发明人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett E. Bouma

    IPC分类号： G02B6/02 ,  G02B6/12 ,  G02B6/26 ,  G02B6/28 ,  G02B6/32 ,  G02B6/36 ,  G02B6/42 ,  G02B6/44 ,  H04J14/02

    CPC分类号： H04J14/0267 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/6852 ,  G02B6/2552 ,  G02B6/262 ,  G02B6/2856

    摘要： Apparatus and method are provided for transmitting at least one electro-magnetic radiation is provided. In particular, at least one optical fiber having at least one end extending along a first axis may be provided. Further, a light transmissive optical arrangement may be provided in optical cooperation with the optical fiber. The optical arrangement may have a first surface having a portion that is perpendicular to a second axis, and a second surface which includes a curved portion. The first axis can be provided at a particular angle that is more than 0° and less than 90° with respect to the second axis.

    摘要翻译： 提供了用于传送至少一个电磁辐射的装置和方法。 特别地，可以提供至少一个具有沿着第一轴线延伸的至少一个端部的光纤。 此外，可以与光纤光学协作地提供透光的光学装置。 光学装置可以具有第一表面，其具有垂直于第二轴线的部分，以及包括弯曲部分的第二表面。 第一轴可以相对于第二轴线以大于0°且小于90°的特定角度设置。

    Method and apparatus for imaging of vessel segments
    5.
    发明授权
    Method and apparatus for imaging of vessel segments 有权

    公开(公告)号：US09763623B2

    公开(公告)日：2017-09-19

    申请号：US12946725

    申请日：2010-11-15

    申请人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett E. Bouma

    发明人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett E. Bouma

    IPC分类号： A61B5/00 ,  A61B5/02

    CPC分类号： A61B5/6852 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007

    摘要： An apparatus, method and software arrangement for imaging a surface of a structure that is in contact with an opaque fluid is provided. The apparatus includes an article of manufacture (e.g., a housing), a fluid delivery arrangement and an imaging arrangement. The housing includes an aperture formed in the article of manufacture. The fluid delivery arrangement is configured to deliver a volume of substantially transparent fluid to the aperture formed in the housing. The imaging arrangement is configured to image the surface of the structure using an imaging modality after the volume of the transparent fluid is delivered to the aperture, wherein the imaging arrangement and/or the article of manufacture is translated along the surface of the structure while imaging the surface of the structure.

    Methods and systems for optical imaging or epithelial luminal organs by beam scanning thereof
    6.
    发明授权
    Methods and systems for optical imaging or epithelial luminal organs by beam scanning thereof 有权
    用于光学成像或上皮腔内器官的方法和系统通过其束扫描

    公开(公告)号：US09087368B2

    公开(公告)日：2015-07-21

    申请号：US11625135

    申请日：2007-01-19

    申请人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett E. Bouma ,  Benjamin J. Vakoc ,  Norman S. Nishioka

    发明人： Guillermo J. Tearney ,  Milen Shishkov ,  Brett E. Bouma ,  Benjamin J. Vakoc ,  Norman S. Nishioka

    IPC分类号： A61B5/06 ,  G06T7/00 ,  A61B5/00

    CPC分类号： A61B5/0084 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/6852 ,  A61B5/7271 ,  G06T7/0012 ,  G06T2207/10056 ,  G06T2207/10101

    摘要： Arrangements, apparatus, systems and systems are provided for obtaining data for at least one portion within at least one luminal or hollow sample. The arrangement, system or apparatus can be (insertable via at least one of a mouth or a nose of a patient. For example, a first optical arrangement can be configured to transceive at least one electromagnetic (e.g., visible) radiation to and from the portion. A second arrangement may be provided at least partially enclosing the first arrangement. Further, a third arrangement can be configured to be actuated so as to position the first arrangement at a predetermined location within the luminal or hollow sample. The first arrangement may be configured to compensate for at least one aberration (e.g., astigmatism) caused by the second arrangement and/or the third arrangement. The second arrangement can include at least one portion which enables a guiding arrangement to be inserted there through. Another arrangement can be provided which is configured to measure a pressure within the at least one portion. The data may include a position and/or an orientation of the first arrangement with respect to the luminal or hollow sample.

    摘要翻译： 提供了布置，装置，系统和系统以获得至少一个管腔或中空样品中的至少一个部分的数据。 该装置，系统或装置可以（可通过患者的嘴部或鼻子中的至少一个插入），例如，第一光学装置可以被配置为收发至少一个电磁（例如，可见） 第二布置可以至少部分地包围第一布置。此外，第三布置可被配置为被致动以将第一布置定位在管腔或中空样品内的预定位置处，第一布置可以是 被配置为补偿由第二布置和/或第三布置引起的至少一个像差（例如，散光），第二布置可以包括使引导布置能够插入到其中的至少一个部分，可以提供另一种布置 其被配置为测量所述至少一个部分内的压力，所述数据可以包括所述第一装置的位置和/或取向与r 对于管腔或空心样品。

    APPARATUS AND METHOD FOR DEVICES FOR IMAGING STRUCTURES IN OR AT ONE OR MORE LUMINAL ORGANS
    7.
    发明申请
    APPARATUS AND METHOD FOR DEVICES FOR IMAGING STRUCTURES IN OR AT ONE OR MORE LUMINAL ORGANS 审中-公开
    用于在一个或更多个LUMINAL器官上形成结构的设备的装置和方法

    公开(公告)号：US20120004506A1

    公开(公告)日：2012-01-05

    申请号：US13152784

    申请日：2011-06-03

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Michalina Gora ,  Melissa Suter ,  Hongki Yoo ,  Milen Shishkov

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Michalina Gora ,  Melissa Suter ,  Hongki Yoo ,  Milen Shishkov

    IPC分类号： A61B1/00

    CPC分类号： A61B1/00082 ,  A61B1/00064 ,  A61B1/00071 ,  A61B1/0008 ,  A61B1/00165 ,  A61B1/00179 ,  A61B5/6852 ,  A61B5/6853

    摘要： In accordance with exemplary embodiments of the present disclosure, device and method can be provided which can facilitate imaging of biological tissues, e.g., luminal organs in vivo, using optical techniques. The exemplary device can include different designs an features of one or more catheters, which can illuminate the tissues, and collect signals from the inside of the lumen. In another exemplary embodiment according to the present disclosure, a balloon-catheter can be provided with the flexible neck, which can absorb most of the bending. According to still another exemplary embodiments of the present disclosure, a balloon-catheter tethered capsule can be provided, and according a yet further exemplary embodiment, a structured balloon design can be provided with one or more protuberances, thus enabling imaging of the structures in close contact, e.g., without compressing of the tissue.

    摘要翻译： 根据本公开的示例性实施例，可以提供可以使用光学技术来促进生物组织例如体内器官的成像的装置和方法。 示例性装置可以包括不同的设计，一个或多个导管的特征可以照亮组织，并从内腔收集信号。 在根据本公开的另一示例性实施例中，球囊导管可以设置有柔性颈部，其可以吸收大部分的弯曲。 根据本公开的另一示例性实施例，可以提供球囊 - 导管系留胶囊，并且根据另外的示例性实施例，结构化球囊设计可以设置有一个或多个突起，从而能够使结构在近距离成像 接触，例如，不压缩组织。

    Microscope objectives
    8.
    发明授权
    Microscope objectives 失效
    显微镜目标

    公开(公告)号：US07684134B2

    公开(公告)日：2010-03-23

    申请号：US10542966

    申请日：2004-01-21

    申请人： Guillermo J. Tearney ,  Constantinos Pitris ,  Milen Shishkov ,  Brett E. Bouma

    发明人： Guillermo J. Tearney ,  Constantinos Pitris ,  Milen Shishkov ,  Brett E. Bouma

    IPC分类号： G02B7/02

    CPC分类号： G02B21/0072 ,  G02B21/006 ,  G02B21/02 ,  G02B21/33

    摘要： A confocal microscope lens arrangement is provided. The confocal microscope lens arrangement includes a lens assembly housing which has a lens assembly, and an exterior housing including a distal end and a proximal end. The exterior housing is configured to allow the lens assembly housing to be placed therein, and translated between the proximal end and the distal end of the exterior housing to focus the lens assembly. The exterior housing has an aperture formed through a distal end thereof. The arrangement also includes an immersion media filling the volume of area between the exterior housing and the lens assembly housing.

    摘要翻译： 提供共焦显微镜透镜装置。 共焦显微镜透镜装置包括具有透镜组件的透镜组件壳体和包括远端和近端的外壳。 外部壳体被配置为允许透镜组件壳体放置在其中并且在外部壳体的近端和远端之间平移以聚焦透镜组件。 外壳具有通过其远端形成的孔。 该布置还包括填充外壳和透镜组件壳体之间的面积的浸没介质。

    System and method for optical coherence imaging
    9.
    发明授权
    System and method for optical coherence imaging 有权
    光学相干成像系统和方法

    公开(公告)号：US07366376B2

    公开(公告)日：2008-04-29

    申请号：US11241907

    申请日：2005-09-29

    申请人： Milen Shishkov ,  Brett Eugene Bouma ,  Guillermo J. Tearney

    发明人： Milen Shishkov ,  Brett Eugene Bouma ,  Guillermo J. Tearney

    IPC分类号： G02B6/32 ,  G02B6/12 ,  G02B6/26 ,  G02B6/42 ,  G02B6/44 ,  G02B6/02 ,  G02B6/028 ,  G02B6/032 ,  G02B6/036

    CPC分类号： H04J14/0267 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/6852 ,  G02B6/2552 ,  G02B6/262 ,  G02B6/2856

    摘要： Apparatus and method are provided for transmitting at least one electro-magnetic radiation is provided. In particular, at least one optical fiber having at least one end extending along a first axis may be provided. Further, a light transmissive optical arrangement may be provided in optical cooperation with the optical fiber. The optical arrangement may have a first surface having a portion that is perpendicular to a second axis, and a second surface which includes a curved portion. The first axis can be provided at a particular angle that is more than 0° and less than 90° with respect to the second axis.

    摘要翻译： 提供了用于传送至少一个电磁辐射的装置和方法。 特别地，可以提供至少一个具有沿着第一轴线延伸的至少一个端部的光纤。 此外，可以与光纤光学协作地提供透光的光学装置。 光学装置可以具有第一表面，其具有垂直于第二轴线的部分，以及包括弯曲部分的第二表面。 第一轴可以相对于第二轴线以大于0°且小于90°的特定角度设置。