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公开(公告)号：US20100168727A1
公开(公告)日：2010-07-01
申请号：US12311550
申请日：2007-10-10
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/1807
摘要： A probe and associated apparatus for treating oesophageal tissue with microwave radiation (e.g. radiation having a frequency of 5-60 GHz) are disclosed. The probe comprises a flexible substrate that expands and retracts between an access configuration, e.g. suitable for insertion through an endoscope, and a treatment configuration in which radiating elements, e.g. conducting patches, monopole antennas, slots in a conducting strip or the like, are brought into close proximity with tissue to be treated. The radiating elements are arranged to emit a substantially uniform electromagnetic field with a suitable penetration depth into the tissue. The apparatus can monitor and control the power delivered from the probe into tissue. A method of hollow tube, e.g. oesophageal, pathological treatment and a device for opening and closing the probe are also disclosed.
摘要翻译： 公开了一种用于用微波辐射（例如频率为5-60GHz的辐射）治疗食管组织的探针和相关装置。 探针包括柔性基底，其在接近构造之间膨胀和缩回，例如， 适用于通过内窥镜的插入，以及处理结构，其中辐射元件例如 导电贴片，单极天线，导电条带中的狭槽等与被处理组织紧密接近。 辐射元件布置成发射具有适当穿透深度进入组织的基本均匀的电磁场。 该装置可以监测和控制从探针传递到组织中的功率。 中空管的方法，例如 还公开了食管，病理治疗和用于打开和关闭探针的装置。
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2.发明授权Apparatus for treating tissue with microwave radiation and antenna calibration system and method 失效用微波辐射处理组织的设备和天线校准系统及方法公开(公告)号：US08653828B2
公开(公告)日：2014-02-18
申请号：US12311553
申请日：2007-10-10
IPC分类号： G01R27/04
CPC分类号： A61B18/1815 , A61B5/0507 , A61B5/053 , A61B18/18 , A61B2017/00725 , A61B2018/00755 , A61B2018/00785 , A61B2018/00875 , A61B2018/1876 , A61N5/02
摘要： A calibration method and apparatus for surgical antennas which are arranged to deliver microwave radiation (e.g. having a treatment frequency of 500 MHz to 100 GHz) into biological tissue is disclosed. An emitting region of the antenna is exposed to a plurality of calibration standards each having a different complex impedance at the treatment frequency. In one embodiment the calibration standards are created in a short-circuit-terminated waveguide cavity of variable length. In another embodiment, each calibration standard is a different mixture of two or more liquids. Measurement of the magnitude and phase of signals reflected from the emitting region when exposed to the calibration standard can permit calibration of the antenna, e.g. by generating a mapping function based on the measured values and known or reference values for the calibration standards. Also disclosed is tissue treatment apparatus having an ablation channel for conveying microwave radiation to a surgical antenna at a high power level and a separate measurement channel for conveying microwave radiation to a surgical antenna at a low power level, wherein the measurement channel bypasses noisy components on the ablation channel. A surgical antenna having an impedance transformer for matching an e.g. coaxial feed structure which terminates in one or more radiating elements with tissue to be treated is also disclosed.
摘要翻译： 公开了一种用于外科天线的校准方法和装置，其被布置为将微波辐射（例如具有500MHz至100GHz的治疗频率）递送到生物组织中。 天线的发射区域暴露于在处理频率处具有不同复阻抗的多个校准标准。 在一个实施例中，在可变长度的短路端接的波导腔中产生校准标准。 在另一个实施方案中，每个校准标准品是两种或更多种液体的不同混合物。 当暴露于校准标准时，从发射区域反射的信号的幅度和相位的测量可以允许天线的校准，例如， 通过基于测量值和校准标准的已知或参考值生成映射函数。 还公开了一种组织处理设备，其具有用于将微波辐射传送到高功率水平的手术天线的消融通道和用于以低功率水平将微波辐射传送到手术天线的单独的测量通道，其中测量通道绕过噪声分量 消融通道。 具有阻抗变换器的手术天线， 还公开了一种终止于一个或多个辐射元件与待处理组织的同轴馈送结构。
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3.发明申请APPARATUS FOR TREATING TISSUE WITH MICROWAVE RADIATION AND ANTENNA CALIBRATION SYSTEM AND METHOD 失效用微波辐射和天线校准系统和方法处理组织的装置公开(公告)号：US20100121318A1
公开(公告)日：2010-05-13
申请号：US12311553
申请日：2007-10-10
CPC分类号： A61B18/1815 , A61B5/0507 , A61B5/053 , A61B18/18 , A61B2017/00725 , A61B2018/00755 , A61B2018/00785 , A61B2018/00875 , A61B2018/1876 , A61N5/02
摘要： A calibration method and apparatus for surgical antennas which are arranged to deliver microwave radiation (e.g. having a treatment frequency of 500 MHz to 100 GHz) into biological tissue is disclosed. An emitting region of the antenna is exposed to a plurality of calibration standards each having a different complex impedance at the treatment frequency. In one embodiment the calibration standards are created in a short-circuit-terminated waveguide cavity of variable length. In another embodiment, each calibration standard is a different mixture of two or more liquids. Measurement of the magnitude and phase of signals reflected from the emitting region when exposed to the calibration standard can permit calibration of the antenna, e.g. by generating a mapping function based on the measured values and known or reference values for the calibration standards. Also disclosed is tissue treatment apparatus having an ablation channel for conveying microwave radiation to a surgical antenna at a high power level and a separate measurement channel for conveying microwave radiation to a surgical antenna at a low power level, wherein the measurement channel bypasses noisy components on the ablation channel. A surgical antenna having an impedance transformer for matching an e.g. coaxial feed structure which terminates in one or more radiating elements with tissue to be treated is also disclosed.
摘要翻译： 公开了一种用于外科天线的校准方法和装置，其被布置为将微波辐射（例如具有500MHz至100GHz的治疗频率）递送到生物组织中。 天线的发射区域暴露于在处理频率处具有不同复阻抗的多个校准标准。 在一个实施例中，在可变长度的短路端接的波导腔中产生校准标准。 在另一个实施方案中，每个校准标准品是两种或更多种液体的不同混合物。 当暴露于校准标准时，从发射区域反射的信号的幅度和相位的测量可以允许天线的校准，例如， 通过基于测量值和校准标准的已知或参考值生成映射函数。 还公开了一种组织处理设备，其具有用于将微波辐射传送到高功率水平的手术天线的消融通道和用于以低功率水平将微波辐射传送到手术天线的单独的测量通道，其中测量通道绕过噪声分量 消融通道。 具有阻抗变换器的手术天线， 还公开了一种终止于一个或多个辐射元件与待处理组织的同轴馈送结构。
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公开(公告)号：US08574227B2
公开(公告)日：2013-11-05
申请号：US12523208
申请日：2007-10-09
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1815
摘要： A surgical antenna for radiating microwave energy (e.g. frequency 500 MHz to 60 GHz) from a e.g. ceramic insertion tip (60) into biological tissue is disclosed. The tip is provided at the end of an elongate body which delivers the microwave energy to the tip via an inner conductor (30), an outer conductor (20) surrounding the inner conductor and a dielectric material (50) therebetween. The impedance of the insertion tip (60) is selected to improve impedance matching with the complex conjugate of the complex impedance of the tissue at a treatment frequency. For example the insertion tip may act as or include at least one quarter wavelength impedance transformer. By closely matching the antenna's impedance to the tissue, dynamic tuning (if used) can be performed much more efficiently. Impedance matching at the tip can also focus the radiated energy distribution.
摘要翻译： 用于从例如太阳能电池辐射微波能量（例如频率500MHz至60GHz）的外科天线。 公开了陶瓷插入尖端（60）进入生物组织。 尖端设置在细长体的端部，其通过内部导体（30），围绕内部导体的外部导体（20）和介于其间的介电材料（50）将微波能传递到尖端。 选择插入尖端（60）的阻抗以改善与处理频率下组织的复阻抗的复共轭的阻抗匹配。 例如，插入尖端可以充当或包括至少四分之一波长阻抗变压器。 通过将天线的阻抗与组织紧密匹配，可以更有效地执行动态调谐（如果使用）。 尖端的阻抗匹配也可以集中辐射能量分布。
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公开(公告)号：US09333034B2
公开(公告)日：2016-05-10
申请号：US13992666
申请日：2011-12-07
CPC分类号： A61B18/1815 , A61B18/042 , A61B18/1206 , A61B2018/0019 , A61B2018/00601 , A61B2018/0063 , A61B2018/00779 , A61B2018/00785 , A61B2018/00827 , A61B2018/00892 , A61B2018/128 , A61B2018/1861 , A61B2018/1876 , H05B6/806
摘要： A control system for electrosurgical apparatus in which the energy delivery profile of both RF EM radiation and microwave EM radiation delivered to a probe is set based on sampled voltage and current information of RF energy conveyed to the probe and/or sampled forward and reflected power information for the microwave energy conveyed to and from the probe. The energy delivery profile for the RF EM radiation is for tissue cutting (without requiring a sharp blade) and the energy delivery profile for the microwave EM radiation is for haemostasis or sealing or coagulation or ablation of tissue. The RF EM radiation and microwave EM radiation may be applied separately or simultaneously.
摘要翻译： 一种电外科设备的控制系统，其中基于传送到探头的RF能量和/或采样的正向和反射功率信息的采样电压和电流信息来设置RF EM辐射和传送到探头的微波EM辐射的能量传递曲线。 用于从探头传出的微波能量。 用于RF EM辐射的能量传递分布用于组织切割（不需要锋利的刀片），并且用于微波EM辐射的能量传递曲线用于组织的止血或密封或凝固或消融。 RF EM辐射和微波EM辐射可以单独或同时应用。
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6.发明申请公开(公告)号：US20100145328A1
公开(公告)日：2010-06-10
申请号：US12517516
申请日：2007-12-03
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1815
摘要： A portable electrosurgical system (100) for treating biological tissue with microwave radiation (e.g. having a frequency between 500 MHz and 60 GHz) is disclosed. The system comprises a hand-held microwave sub-assembly (102) which generates and amplifies a microwave signal (which may be continuous or modulated) for treatment and includes a treatment antenna (116) for delivering the radiation. Diode detectors (120, 122) in the sub-assembly (102) may detect forward and reflected power levels to enable determination of net delivered power. A dynamic impedance matching system may be provided to match energy developed by amplifiers (110, 112) in the sub-assembly (102) to the biological tissue load. A tuning filter (144) and couplers (146, 148, 150, 152) for extracting magnitude and phase information from the microwave signal are thus provided in the sub-assembly.
摘要翻译： 公开了一种用于用微波辐射（例如具有500MHz和60GHz之间的频率）处理生物组织的便携式电外科系统（100）。 该系统包括手持微波子组件（102），其产生并放大用于处理的微波信号（其可以是连续的或调制的），并且包括用于传送辐射的处理天线（116）。 子组件（102）中的二极管检测器（120,122）可以检测正向和反射的功率电平，以确定净输送功率。 可以提供动态阻抗匹配系统以将由子组件（102）中的放大器（110,112）开发的能量与生物组织负载相匹配。 因此，在子组件中提供用于从微波信号提取幅度和相位信息的调谐滤波器（144）和耦合器（146,148,150,152）。
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公开(公告)号：US09636176B2
公开(公告)日：2017-05-02
申请号：US13997915
申请日：2012-01-09
CPC分类号： A61B18/1815 , A61B2018/00202 , A61B2018/00571 , A61B2018/1876 , A61B2018/1892 , H01Q1/36 , H01Q13/08 , H01Q21/06
摘要： An electrosurgical instrument for delivering radiofrequency (RF) electromagnetic (EM) energy and microwave frequency EM energy from a coaxial feed cable through an instrument tip into tissue. The instrument tip comprises a dielectric body separating first and second conductive elements, which act as active and return electrodes to convey the RF EM radiation by conduction, and as an antenna to radiate the microwave EM radiation. The instrument also has a fluid feed incorporated into its tip, e.g. in an additional dielectric element mounted on the underside of the tip, for delivering fluid. The delivered fluid may be a gas plasma to assist treatment or a liquid to plump up a tissue region before treatment. The instrument may fit in an endoscope.
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公开(公告)号：US09033971B2
公开(公告)日：2015-05-19
申请号：US13378552
申请日：2010-07-20
CPC分类号： H01Q21/08 , A61B18/18 , A61B18/1815 , A61B2018/00642 , A61B2018/0066 , A61B2018/00708 , A61B2018/00785 , A61B2018/00869 , A61B2018/00875 , A61B2018/1853 , H01Q1/22 , H01Q1/42 , H01Q3/24 , H01Q21/0075
摘要： A surgical spatula (10, 34) has a flat paddle (38, 62) and a handle extending away from a first end of the flat paddle (38, 62). The handle has a coaxial power feed (64, 130) which is connectable to receive energy from a microwave power source. The paddle (38, 62) contains a microwave conveying structure connected to the coaxial power feed (64, 130). The microwave conveying structure is enclosed at a front end of the paddle (38, 62) opposite to the first end so that microwave radiation is blocked from being emitted from the front end. The microwave conveying structure is open along a side of the paddle (38, 62) which extends away from the first end to permit a microwave radiation field to be emitted from that side.
摘要翻译： 手术刮刀（10,34）具有平坦的桨叶（38,62）和从平板桨（38,62）的第一端延伸的手柄。 手柄具有可连接以从微波电源接收能量的同轴馈电（64,130）。 桨（38,62）包含连接到同轴馈电（64,130）的微波输送结构。 微波输送结构封闭在与第一端相对的桨叶（38,62）的前端，使得微波辐射被阻止从前端发射。 微波输送结构沿着从第一端延伸的桨叶（38,62）的侧面开口以允许从该侧发射微波辐射场。
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公开(公告)号：US08768485B2
公开(公告)日：2014-07-01
申请号：US10536721
申请日：2003-11-27
CPC分类号： A61B18/18 , A61B18/1815 , A61B2018/00642 , A61B2018/00702 , A61B2018/00755 , A61B2018/00779 , A61B2018/00869 , A61B2018/00875 , H05B6/686 , H05B6/705 , H05B6/806
摘要： An apparatus and method for ablating tissue is disclosed. The apparatus comprises a source of microwave radiation (1), a probe (5) for directing the microwave radiation into tissue, one or more detectors for detecting the power and phase of the microwave radiation and an impedance adjuster (50) for adjusting impedance so as to minimize the amount of microwave radiation which reflected back through the probe. The detector or detectors use a local oscillator (230) to derive the phase information. A modulator for modulating the microwave radiation to a cutting frequency is also disclosed.
摘要翻译： 公开了一种用于消融组织的装置和方法。 该装置包括微波辐射源（1），用于将微波辐射引导到组织中的探针（5），用于检测微波辐射的功率和相位的一个或多个检测器和用于调节阻抗的阻抗调节器（50） 以便最小化通过探针反射回的微波辐射的量。 检测器或检测器使用本地振荡器（230）来导出相位信息。 还公开了一种用于将微波辐射调制到切割频率的调制器。
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10.发明申请公开(公告)号：US20130289557A1
公开(公告)日：2013-10-31
申请号：US13997915
申请日：2012-01-09
IPC分类号： A61B18/18
CPC分类号： A61B18/1815 , A61B2018/00202 , A61B2018/00571 , A61B2018/1876 , A61B2018/1892 , H01Q1/36 , H01Q13/08 , H01Q21/06
摘要： An electrosurgical instrument for delivering radiofrequency (RF) electromagnetic (EM) energy and microwave frequency EM energy from a coaxial feed cable through an instrument tip into tissue. The instrument tip comprises a dielectric body separating first and second conductive elements, which act as active and return electrodes to convey the RF EM radiation by conduction, and as an antenna to radiate the microwave EM radiation. The instrument also has a fluid feed incorporated into its tip, e.g. in an additional dielectric element mounted on the underside of the tip, for delivering fluid. The delivered fluid may be a gas plasma to assist treatment or a liquid to plump up a tissue region before treatment. The instrument may fit in an endoscope.
摘要翻译： 一种用于将射频（RF）电磁（EM）能量和微波频率EM能量从同轴馈电电缆通过仪器尖端传送到组织中的电外科仪器。 器械尖端包括分离第一和第二导电元件的电介质体，其作为有源和返回电极，以通过导电传送RF EM辐射，以及用作辐射微波EM辐射的天线。 仪器还具有并入其尖端的流体进料，例如 在安装在尖端下侧的附加电介质元件中，用于输送流体。 输送的流体可以是气体等离子体，以在处理之前帮助治疗或液体丰满组织区域。 仪器可以装在内窥镜中。
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