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    Method and system for classification of photo-plethysmographically detected respiratory effort
    1.
    发明授权
    Method and system for classification of photo-plethysmographically detected respiratory effort 有权
    光体积描记检测呼吸功能分类方法及系统

    公开(公告)号：US08365730B2

    公开(公告)日：2013-02-05

    申请号：US12409685

    申请日：2009-03-24

    申请人： Clark R. Baker, Jr. ,  Michael O'Neil ,  Shannon Campbell ,  Gilbert Hausmann

    发明人： Clark R. Baker, Jr. ,  Michael O'Neil ,  Shannon Campbell ,  Gilbert Hausmann

    IPC分类号： A61M15/00 ,  F16K31/02

    CPC分类号： A61M16/0069 ,  A61B5/0205 ,  A61B5/02416 ,  A61B5/1455 ,  A61B5/4818 ,  A61B5/726 ,  A61M16/0003 ,  A61M16/0057 ,  A61M2205/18 ,  A61M2205/33 ,  A61M2205/50 ,  A61M2230/20 ,  A61M2230/205 ,  A61M2230/40

    摘要： Embodiments disclosed herein may include systems and methods for determining a patient's respiratory effort and blood oxygen saturation based on data acquired from a pulse oximetry sensor and analyzing the parameters in conjunction with each other. For example, the respiratory effort may be determined based on a photo-plethysmographic waveform generated from light attenuation detected by the sensor, and the blood oxygen saturation may be a pulse -based estimate of arterial blood oxygen saturation determined from the detected attenuation. Analysis of the parameters may enable detection and classification of apnea (e.g., obstructive or central) or another underlying cause for respiratory instability. Furthermore, the measured respiratory effort may be compared to respiratory effort supplied by a ventilator to ensure proper sensor placement before enabling automatic adjustment of ventilator settings.

    摘要翻译： 本文公开的实施例可以包括基于从脉搏血氧饱和度传感器获取的数据并且相互结合地分析参数来确定患者的呼吸力和血氧饱和度的系统和方法。 例如，可以基于由传感器检测到的光衰减产生的光体积描记图波形来确定呼吸力，并且血氧饱和度可以是从检测到的衰减确定的基于脉搏的动脉血氧饱和度的估计。 参数分析可以检测和分类呼吸暂停（例如阻塞性或中枢性）或呼吸不稳定性的其他潜在原因。 此外，测量的呼吸努力量可以与呼吸机提供的呼吸作用进行比较，以确保在进行呼吸机设置的自动调节之前适当的传感器放置。

    Method for detection of aberrant tissue spectra
    4.
    发明授权
    Method for detection of aberrant tissue spectra 有权

    公开(公告)号：US09801584B2

    公开(公告)日：2017-10-31

    申请号：US13598312

    申请日：2012-08-29

    申请人： Clark R. Baker, Jr.

    发明人： Clark R. Baker, Jr.

    IPC分类号： A61B5/1455 ,  A61B5/00

    CPC分类号： A61B5/6843 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/7203

    摘要： A method is provided for determining contact of a sensor with a patient's tissue. The method comprises comparing the intensity of detected light at a first wavelength to a threshold, wherein the first wavelength is not used to determine a physiological characteristic of the patient, and determining if the sensor is in contact with the patient's tissue based on the comparison. In addition, a method is provided for determining the amount of light shunting during operation of the sensor. The method comprises comparing the intensity of detected light at a first wavelength to a threshold, wherein the first wavelength is not used to determine a physiological characteristic of the patient, and determining the amount of light shunting based on the comparison.

    Method for improved oxygen saturation estimation in the presence of noise
    5.
    发明授权
    Method for improved oxygen saturation estimation in the presence of noise 有权
    在存在噪声的情况下改进氧饱和度估计的方法

    公开(公告)号：US08862194B2

    公开(公告)日：2014-10-14

    申请号：US12165256

    申请日：2008-06-30

    申请人： Clark R. Baker, Jr.

    发明人： Clark R. Baker, Jr.

    IPC分类号： A61B5/00 ,  A61B5/1455

    CPC分类号： A61B5/7203 ,  A61B5/14551 ,  A61B5/7264 ,  A61B5/7282 ,  A61B5/7405 ,  A61B5/742 ,  A61B5/7455

    摘要： The present disclosure relates, according to some embodiments, to devices, systems, and methods for estimating a physiological parameter in the presence of noise. For example, the disclosure relates, in some embodiments, to devices, systems, and methods for assessing (e.g., estimating, measuring, calculating) oxygen saturation (SpO2). Methods of assessing SpO2 may include assessing a noise metric associated with motion artifact. In some embodiments, a percentage (e.g., an empirically determined percentage) of a noise metric may be simply added to the SpO2 estimate to produce a corrected SpO2 estimate. An oximetry algorithm may include, according to some embodiments, combining multiple internal SpO2 estimates and associated noise and/or signal quality metrics (e.g., using a radial basis neural network) to produce a modified (e.g., corrected) SpO2 estimate (e.g., rather than merely selecting the estimate from a finite number of candidates). A modified SpO2 estimate may include little or no movement-based error.

    摘要翻译： 根据一些实施例，本公开涉及用于在存在噪声的情况下估计生理参数的装置，系统和方法。 例如，在一些实施例中，本公开涉及用于评估（例如，估计，测量，计算）氧饱和度（SpO2）的装置，系统和方法。 评估SpO2的方法可能包括评估与运动伪影相关的噪声指标。 在一些实施例中，噪声度量的百分比（例如经验确定的百分比）可以简单地添加到SpO2估计值以产生校正的SpO2估计。 根据一些实施例，血氧测定算法可以包括组合多个内部SpO2估计和相关联的噪声和/或信号质量度量（例如，使用径向基神经网络）以产生经修改（例如，校正的）SpO2估计（例如， 而不仅仅是从有限数量的候选人中选择估计）。 修改的SpO2估计可能包括很少或没有基于运动的错误。

    Reducing nuisance alarms
    6.
    发明授权
    Reducing nuisance alarms 有权
    减少有害警报

    公开(公告)号：US08792949B2

    公开(公告)日：2014-07-29

    申请号：US12399304

    申请日：2009-03-06

    申请人： Clark R. Baker, Jr.

    发明人： Clark R. Baker, Jr.

    IPC分类号： A61B5/1455

    CPC分类号： A61B5/14552 ,  A61B5/14551 ,  A61B5/7221 ,  A61B5/746 ,  G06F19/00 ,  G06F19/3418 ,  G16H40/63

    摘要： Embodiments disclosed herein may describe systems and methods for reducing nuisance alarms using probability and/or accuracy of a measured physiological parameter, such as the pulse rate or SpO2 measurement generated by a pulse oximeter. Embodiments may include methods for adjusting a predetermined alarm threshold based on the probability distribution of the estimated pulse rate and/or oxygen saturation of a patient's blood.

    摘要翻译： 本文公开的实施例可以描述使用测量的生理参数（例如由脉搏血氧计产生的脉搏率或SpO2测量）的概率和/或精度来减少麻烦警报的系统和方法。 实施例可以包括基于患者血液的估计脉率和/或氧饱和度的概率分布来调整预定警报阈值的方法。

    Method and apparatus for detecting and analyzing variations in a physiologic parameter
    7.
    发明授权
    Method and apparatus for detecting and analyzing variations in a physiologic parameter 失效
    用于检测和分析生理参数变化的方法和装置

    公开(公告)号：US08509869B2

    公开(公告)日：2013-08-13

    申请号：US12467003

    申请日：2009-05-15

    申请人： Clark R. Baker, Jr. ,  Paul D. Mannheimer

    发明人： Clark R. Baker, Jr. ,  Paul D. Mannheimer

    IPC分类号： A61B5/00

    CPC分类号： A61B5/14551

    摘要： The present disclosure is generally directed to identifying and/or analyzing high resolution variations in a measured physiologic parameter, such as blood oxygen saturation (SpO2) measured using pulse oximetry. Present embodiments may include a system including a sensor comprising an emitter capable of emitting light at different wavelengths into a tissue bed, and a detector capable of detecting the light from the emitter after dispersion and/or reflection by the tissue bed. Further, the system may include a pulse oximeter capable of receiving signals from the sensor that are indicative of characteristics of the light detected by the detector, and utilizing the signals to estimate blood oxygen saturation values over time at a high resolution to facilitate detection of variations in the blood oxygen saturation values that are smaller in magnitude than an accuracy, display precision, and/or calibration of the blood oxygen saturation values.

    摘要翻译： 本公开通常涉及鉴定和/或分析测量的生理参数中的高分辨率变化，例如使用脉搏血氧测定法测量的血氧饱和度（SpO2）。 本实施例可以包括包括传感器的系统，该传感器包括能够将不同波长的光发射到组织床中的发射器，以及能够在由组织床分散和/或反射之后检测来自发射体的光的检测器。 此外，该系统可以包括能够接收来自传感器的信号的脉搏血氧计，其指示由检测器检测到的光的特性，并且利用该信号以高分辨率随时间推定血氧饱和度值，以便于检测变化 在血氧饱和度值的范围内比血氧饱和度值的精度，显示精度和/或校准更小。

    Estimation of a physiological parameter using a neural network
    8.
    发明授权
    Estimation of a physiological parameter using a neural network 有权
    使用神经网络估计生理参数

    公开(公告)号：US08457706B2

    公开(公告)日：2013-06-04

    申请号：US12467013

    申请日：2009-05-15

    申请人： Clark R. Baker, Jr.

    发明人： Clark R. Baker, Jr.

    IPC分类号： A61B5/00

    CPC分类号： A61B5/7264 ,  A61B5/14551 ,  A61B5/7221 ,  A61B5/725 ,  G06F19/00 ,  G16H50/20

    摘要： A neural network is used to combine one or more estimates of a physiologic parameter with one or more associated signal quality metrics, creating a more accurate estimate of said physiologic parameter, as well as a second estimate of the accuracy of said physiologic parameter estimate.

    摘要翻译： 神经网络用于将生理参数的一个或多个估计与一个或多个相关联的信号质量度量相结合，产生对所述生理参数的更准确的估计，以及所述生理参数估计的准确度的第二估计。

    Nuisance alarm reduction method for therapeutic parameters
    9.
    发明授权
    Nuisance alarm reduction method for therapeutic parameters 有权
    治疗参数的麻烦报警降低方法

    公开(公告)号：US08400290B2

    公开(公告)日：2013-03-19

    申请号：US12689900

    申请日：2010-01-19

    申请人： Clark R. Baker, Jr.

    发明人： Clark R. Baker, Jr.

    IPC分类号： G08B23/00

    CPC分类号： G06F3/0484 ,  A61M16/0051 ,  A61M16/0063 ,  A61M16/024 ,  A61M16/12 ,  A61M2016/0018 ,  A61M2016/0039 ,  A61M2016/1025 ,  A61M2205/18 ,  A61M2205/505 ,  G16H40/63

    摘要： This disclosure describes systems and methods for reducing nuisance alarms associated with monitoring non-physiological parameters in a ventilatory system. Non-physiological parameters may include, but are not limited to, parameters that are internally monitored by the ventilator based on pre-configured ranges dictated by the manufacturer, by an applicable protocol, or by the clinician. Embodiments described herein seek to mitigate nuisance alarms by basing alarm conditions, at least in part, on an integral threshold such that an alarm is not generated when a monitored parameter briefly falls outside an acceptable range by a slight degree, but such that an alarm is generated when a monitored parameter falls outside an acceptable range by a more significant magnitude and/or duration.

    摘要翻译： 本公开描述了用于减少与在通气系统中监测非生理参数相关联的麻烦警报的系统和方法。 非生理参数可以包括但不限于由通过呼吸机内部监测的参数，所述参数基于由制造商指定的预先配置的范围，适用的协议或由临床医生指定。 本文描述的实施例旨在通过将警报条件至少部分地基于积分阈值来基于警报状况来减轻妨扰警报，使得当监视的参数短暂地略微落在可接受范围之外但是使得警报是 当监视的参数在可接受的范围内超出更大的幅度和/或持续时间时产生。