摘要:
A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.
摘要:
A biochip device comprising a substrate constituted by at least one plate of material forming a multimode planar waveguide and carrying chromophore elements suitable for emitting fluorescence in response to excitation by guided waves having an evanescent portion, the device being characterized in that it includes coupling means for coupling excitation light with the waveguide in the form of guided waves, the coupling means being substantially non-directional.
摘要:
An imaging method and a device for detecting the fluorescence of a biochip by illuminating chromophores associated with probes (14) of a substrate (12) placed on a sensor (10) having photodetectors, e.g. of the CCD or CMOS type, a stop filter that rejects the excitation light of the chromophores being provided between the probes (14) and the sensor, the substrate (12) being separable from the sensor (10) after use so as to enable the sensor to be reused.
摘要:
An imaging method and a device for detecting the fluorescence of a biochip by illuminating chromophores associated with probes (14) of a substrate (12) placed on a sensor (10) having photodetectors, e.g. of the CCD or CMOS type, a stop filter that rejects the excitation light of the chromophores being provided between the probes (14) and the sensor, the substrate (12) being separable from the sensor (10) after use so as to enable the sensor to be reused.
摘要:
A device for supporting chromophore elements comprises a plane mirror covered in a layer of material that is transparent at the wavelengths to be detected, said layer having a set of spots on which the chromophore elements are fixed, the spots being subdivided into a plurality of zones of different thicknesses so as to cause the intensity of the fluorescence emitted by the chromophore elements to vary by destructive interference or by constructive interference, respectively.
摘要:
An improved biochip type device comprising a substrate (10) including an intermediate non-absorbent multilayer mirror (12) covered by a layer (14) of high refractive index material having chromophore elements (16) fixed thereon, the layer (14) further including feature (24) for extracting guided-mode light in order to recover the light emitted by the chromophore elements (16) into the layer (14) in response to light excitation, and direct the light to detection and measurement means.
摘要:
A method of fabricating an integrated detection biosensor, the biosensor comprising an assembly (10) of photodetectors (12) of CCD or CMOS type on which there is deposited or formed a filter for rejecting excitation light λe, the filter comprising at least one absorbent layer (14) together with a Bragg mirror or an interference filter, forming a support for chromophore elements that are to be illuminated by the excitation light λe.
摘要:
A white, single or multi-color light emitting diode (LED) includes a mirror for reflecting photons within the LED; a first active region, adjacent the mirror, including one or more current-injected layers for emitting photons when electrically biased in a forward direction; a second active region, adjacent the first active region, including one or more optically-pumped layers for emitting photons, wherein the optically-pumped layers are optically excited by the photons emitted by the current-injected layers, thereby recycling guided modes; and an output interface, adjacent the second active region, for allowing the photons emitted by the optically-pumped layers to escape the LED as emitted light.
摘要:
A device for supporting chromophoric elements comprises support means (1) for receiving, on an upper face (24), chromophoric elements (5) that can emit light under selected conditions, and means for concentrating light (3) to recover the light emitted by each chromophoric element (5) in a portion of the region around it and “deliver” that recovered light to a collecting device.
摘要:
A device for directional and wavelength-selective optical coupling formed in a photonic crystal (12) and comprising two parallel waveguides (14, 16) separated by a coupling zone (18) enabling a particular frequency to be extracted from a signal (30) injected in fundamental mode into one of the waveguide (14) and to recover said frequency at the outlet (34) of the other waveguide (16), extraction and injection being performed by coupling between fundamental and high order modes in each waveguide.