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公开(公告)号:US20190144482A1
公开(公告)日:2019-05-16
申请号:US16094845
申请日:2017-04-21
Applicant: Complete Genomics, Inc. , BGI Shenzhen
Inventor: Handong Li , Snezana Drmanac , Radoje Drmanac , Xun Xu , Lingling Peng , Scott Gablenz
IPC: C07H15/04 , C07H19/10 , C07H21/04 , C07H19/20 , C12Q1/6869
Abstract: Reversibly blocked nucleoside analogues and methods of using such nucleoside analogues for sequencing of nucleic acids are provided.
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2.
公开(公告)号:US10190162B2
公开(公告)日:2019-01-29
申请号:US14921466
申请日:2015-10-23
Applicant: Complete Genomics, Inc.
Inventor: Snezana Drmanac , Handong Li , Radoje Drmanac , Eric Harness , Chongjun Xu
IPC: C12Q1/68 , C12Q1/6874 , C07H19/207 , C07H19/10 , C07H19/20 , C12Q1/6869
Abstract: Novel fluorescent nucleotide analogs are provided herein. Also provided herein are methods of using the nucleotide analogs in sequencing-by-synthesis and signal confinement methods.
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公开(公告)号:US20180223358A1
公开(公告)日:2018-08-09
申请号:US15862566
申请日:2018-01-04
Applicant: Complete Genomics, Inc. , BGI Shenzhen
Inventor: Radoje Drmanac , Snezana Drmanac , Handong Li , Xun Xu , Matthew J. Callow , Leon Eckhardt , Naibo Yang , Quan Ding
IPC: C12Q1/6874 , C12Q1/6876
CPC classification number: C12Q1/6874 , A61K47/00 , C07K16/2851 , C07K16/44 , C07K2317/73 , C12Q1/6804 , C12Q1/6869 , C12Q1/6876 , C12Q2525/186
Abstract: The invention provides compositions and methods for sequencing nucleic acids and other applications. In sequencing by synthesis, unlabeled reversible terminators are incorporated by a polymerase in each cycle, then labeled after incorporation by binding to the reversible terminator a directly or indirectly labeled antibody or other affinity reagent.
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4.SIGNAL CONFINEMENT SEQUENCING (SCS) AND NUCLEOTIDE ANALOGUES FOR SIGNAL CONFINEMENT SEQUENCING 审中-公开
Title translation: 信号约束测序(SCS)和信号约束测序的核苷酸类似物公开(公告)号:US20160130647A1
公开(公告)日:2016-05-12
申请号:US14921466
申请日:2015-10-23
Applicant: Complete Genomics, Inc.
Inventor: Snezana Drmanac , Handong Li , Radoje Drmanac , Eric Harness , Chongjun Xu
IPC: C12Q1/68 , C07H19/10 , C07H19/207
CPC classification number: C12Q1/6874 , C07H19/10 , C07H19/20 , C07H19/207 , C12Q1/6869 , C12Q2525/113 , C12Q2563/131
Abstract: Novel fluorescent nucleotide analogues are provided herein. Also provided herein are methods of using the nucleotide analogues in sequencing-by-synthesis and signal confinement methods.
Abstract translation: 本文提供了新的荧光核苷酸类似物。 本文还提供了在合成序列和信号限制方法中使用核苷酸类似物的方法。
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公开(公告)号:US10988501B2
公开(公告)日:2021-04-27
申请号:US16094845
申请日:2017-04-21
Applicant: Complete Genomics, Inc. , BGI Shenzhen
Inventor: Handong Li , Snezana Drmanac , Radoje Drmanac , Xun Xu , Lingling Peng , Scott Gablenz
IPC: C07H19/10 , C07H19/20 , C07H15/04 , C12Q1/6869 , C07H21/04
Abstract: Reversibly blocked nucleoside analogues and methods of using such nucleoside analogues for sequencing of nucleic acids are provided.
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公开(公告)号:US20170240961A1
公开(公告)日:2017-08-24
申请号:US15440920
申请日:2017-02-23
Applicant: Complete Genomics, Inc.
Inventor: Radoje Drmanac , Snezana Drmanac , Handong Li , Xun Xu
IPC: C12Q1/68
CPC classification number: C12Q1/6869 , C07H21/04 , C12Q1/6876 , C12Q2535/113 , C12Q2563/107 , C12Q2563/131
Abstract: Nucleoside analogues and methods of using such nucleoside analogues for sequencing of nucleic acids are provided.
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