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公开(公告)号:US06468760B1
公开(公告)日:2002-10-22
申请号:US09723820
申请日:2000-11-28
IPC分类号: C12Q142
CPC分类号: G01N33/56961 , Y10S435/922 , Y10S435/942 , Y10S435/968 , Y10S435/975
摘要: The present invention provides high throughput screening systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
摘要翻译: 本发明提供用于鉴定抗真菌化合物的高通量筛选系统。 该方法可以多次同时进行荧光或吸光度读数。
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公开(公告)号:US06627408B1
公开(公告)日:2003-09-30
申请号:US10270085
申请日:2002-10-11
IPC分类号: C12Q142
CPC分类号: G01N33/56961 , Y10S435/922 , Y10S435/942 , Y10S435/968 , Y10S435/975
摘要: The present invention provides high throughput screening Systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
摘要翻译: 本发明提供用于鉴定抗真菌化合物的高通量筛选系统。 该方法可以多次同时进行荧光或吸光度读数。
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公开(公告)号:US06284480B1
公开(公告)日:2001-09-04
申请号:US09541782
申请日:2000-04-03
IPC分类号: C12Q142
CPC分类号: G01N33/56961 , Y10S435/922 , Y10S435/942 , Y10S435/968 , Y10S435/975
摘要: The present invention provides high throughput screening systems for identifying antifungal compounds. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
摘要翻译: 本发明提供用于鉴定抗真菌化合物的高通量筛选系统。 该方法可以多次同时进行荧光或吸光度读数。
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公开(公告)号:US06437115B1
公开(公告)日:2002-08-20
申请号:US09592037
申请日:2000-06-12
IPC分类号: C07H2104
CPC分类号: G01N33/502 , G01N33/5011 , G01N33/57484 , G01N33/57496 , G01N2500/04
摘要: Described herein are methods that can be used for diagnosis and prognosis of cellular proliferation. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate cellular proliferation. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in cancers are described.
摘要翻译: 本文描述了可用于细胞增殖的诊断和预后的方法。 本文还描述了可用于筛选候选生物活性剂以调节细胞增殖能力的方法。 此外,描述了用于癌症治疗性干预的方法和分子靶标(基因及其产物)。
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公开(公告)号:US06379912B1
公开(公告)日:2002-04-30
申请号:US09723262
申请日:2000-11-27
IPC分类号: C12Q144
CPC分类号: C07K14/475
摘要: The invention provides isolated nucleic acid and amino acid sequences of HsKif15, antibodies to HsKif15, methods of screening for HsKif15 modulators using biologically active HsKif15, and kits for screening for HsKif15 modulators.
摘要翻译: 本发明提供HsKif15的分离的核酸和氨基酸序列,HsKif15的抗体,使用生物活性HsKif15筛选HsKif15调节剂的方法,以及用于筛选HsKif15调节剂的试剂盒。
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公开(公告)号:US20050130143A1
公开(公告)日:2005-06-16
申请号:US10486057
申请日:2002-08-09
申请人: Fady Malik , Christophe Beraud , Richard Freedman , Andrew Craven , Roman Sakowicz , James Hartman
发明人: Fady Malik , Christophe Beraud , Richard Freedman , Andrew Craven , Roman Sakowicz , James Hartman
IPC分类号: G01N33/50 , C07K14/47 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12Q1/34 , G01N33/15 , C12Q1/68 , C07H21/04 , C07K16/40 , C12N9/22
CPC分类号: C07K14/4716
摘要: The invention provides novel compositions, methods, and uses of hSMMyHC polypeptides and polynucleotides.
摘要翻译: 本发明提供hSMMyHC多肽和多核苷酸的新型组合物,方法和用途。
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公开(公告)号:US06440684B1
公开(公告)日:2002-08-27
申请号:US09592054
申请日:2000-06-12
IPC分类号: C12N916
CPC分类号: C12N9/14 , C12N9/16 , C12Q1/34 , G01N33/6893 , G01N2500/00
摘要: The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
摘要翻译: 本发明提供用于鉴定可用于治疗细胞增殖障碍的化合物的高通量筛选系统。 该方法可以多次同时进行荧光或吸光度读数。
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公开(公告)号:US06331424B1
公开(公告)日:2001-12-18
申请号:US09594669
申请日:2000-06-15
申请人: Christophe Beraud , Roman Sakowicz
发明人: Christophe Beraud , Roman Sakowicz
IPC分类号: C12N916
摘要: The present invention provides high throughput screening systems for identifying compounds useful in the treatment of cellular proliferation disorders. The method can be performed in plurality simultaneously with fluorescence or absorbance readouts.
摘要翻译: 本发明提供用于鉴定可用于治疗细胞增殖障碍的化合物的高通量筛选系统。 该方法可以多次同时进行荧光或吸光度读数。
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公开(公告)号:US07462482B2
公开(公告)日:2008-12-09
申请号:US10486057
申请日:2002-08-09
申请人: Fady Malik , Christophe Beraud , Richard Freedman , Andrew Craven , Roman Sakowicz , James Hartman
发明人: Fady Malik , Christophe Beraud , Richard Freedman , Andrew Craven , Roman Sakowicz , James Hartman
CPC分类号: C07K14/4716
摘要: The invention provides novel compositions, methods, and uses of hSMMyHC polypeptides and polynucleotides.
摘要翻译: 本发明提供hSMMyHC多肽和多核苷酸的新型组合物,方法和用途。
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公开(公告)号:US07247473B2
公开(公告)日:2007-07-24
申请号:US10723148
申请日:2003-11-25
申请人: Christophe Beraud , Andrew Craven , Ming Yu , Roman Sakowicz , Umesh A. Patel , Katherine A. Davies
发明人: Christophe Beraud , Andrew Craven , Ming Yu , Roman Sakowicz , Umesh A. Patel , Katherine A. Davies
IPC分类号: C12N15/63
CPC分类号: C12N9/14
摘要: The invention provides isolated nucleic acid and amino acid sequences of HsKip3, antibodies to HsKip3, methods of screening for HsKip3a modulators using biologically active HsKip3, and kits for screening for HsKip3a modulators.
摘要翻译: 本发明提供HsKip3的分离的核酸和氨基酸序列,HsKip3的抗体,使用生物活性HsKip3筛选HsKip3a调节剂的方法,以及用于筛选HsKip3a调节剂的试剂盒。
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