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公开(公告)号:US20200205431A1
公开(公告)日:2020-07-02
申请号:US16622163
申请日:2018-06-11
Applicant: DSM IP Assets B.V.
Inventor: Claire Emile PRICE , Hugo STREEKSTRA , Fenna Johanna Catharina JOLINK , Pim VAN HEE , Dominik Bohdan GRABINSKI
Abstract: The present invention relates to a frozen enzyme formulation comprising an enzyme. According to another aspect the present invention relates to a starter culture comprising a frozen enzyme formulation and frozen lactic acid bacteria pellets, wherein the frozen enzyme formulation pellets and the frozen lactic acid bacteria pellets are separate pellets or wherein the enzyme and the lactic acid bacteria are in the same pellets. According to yet another aspect the present invention relates to a method for the production of a frozen enzyme formulation. According to another aspect, the present invention relates to the use of the frozen enzyme formulation.
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公开(公告)号:US20210189015A1
公开(公告)日:2021-06-24
申请号:US17197476
申请日:2021-03-10
Applicant: DSM IP ASSETS B.V.
Inventor: Cornelia Elizabeth Paulina MALJAARS , Pim VAN HEE
IPC: C08B37/00 , C12R1/46 , A23C9/123 , C08L5/00 , C12P19/04 , A23C9/137 , A23C19/032 , A23C19/09 , A23C9/13 , A23C19/05 , C12N1/20
Abstract: The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
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公开(公告)号:US20170218468A1
公开(公告)日:2017-08-03
申请号:US15119708
申请日:2015-02-20
Applicant: DSM IP ASSETS B.V.
Inventor: Roelof Hendrik Matthijs KOUWEN , Pim VAN HEE , Douwe VAN SINDEREN , Brian MCDONNELL , Jennifer MAHONY
CPC classification number: C12R1/46 , A23C9/1238 , A23C19/0323 , A23Y2240/75 , C12N1/04 , C12N1/20 , C12N15/01 , C12Q1/689 , G06F19/22
Abstract: Bacteriophage Insensitive Mutants (BIMs) of three Streptococcus thermophilus parent strains were generated and characterized for phage sensitivity, sedimentation rate, cell chain length, phage adsorption and CRISPR loci alterations. Several BIMs showed an altered sedimentation phenotype as well as an increase cell chain length, reduced phage sensitivity, reduced phage adsorption and 100% identity in three CRISPR loci. The results show that the derived BIMs have become phage-resistant through a mechanism other than CRISPR.
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公开(公告)号:US20240032553A1
公开(公告)日:2024-02-01
申请号:US18483899
申请日:2023-10-10
Applicant: DSM IP Assets B.V.
Inventor: Claire Emile PRICE , Hugo STREEKSTRA , Fenna Johanna Catharina JOLINK , Pim VAN HEE , Dominik Bohdan GRABINSKI
CPC classification number: A23C9/1232 , A23C9/1206 , A23C9/1209 , C12N9/2402 , C12N9/6483 , C12Y302/01108 , C12Y304/23004
Abstract: The present invention relates to a frozen enzyme formulation comprising an enzyme. According to another aspect the present invention relates to a starter culture comprising a frozen enzyme formulation and frozen lactic acid bacteria pellets, wherein the frozen enzyme formulation pellets and the frozen lactic acid bacteria pellets are separate pellets or wherein the enzyme and the lactic acid bacteria are in the same pellets. According to yet another aspect the present invention relates to a method for the production of a frozen enzyme formulation. According to another aspect, the present invention relates to the use of the frozen enzyme formulation.
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公开(公告)号:US20230348950A1
公开(公告)日:2023-11-02
申请号:US17796487
申请日:2021-01-28
Applicant: DSM IP ASSETS B.V.
Inventor: Pim VAN HEE
IPC: C12P39/00 , A23C9/123 , A23C19/06 , C12Q1/70 , C12Q1/6851
CPC classification number: C12P39/00 , A23C9/123 , A23C19/061 , C12Q1/701 , C12Q1/6851
Abstract: A method, process, and computer program for determining an order in which a food product is successively cultured with a set of bacterial cultures in a process for producing a fermented food product, each bacterial culture of the set of bacterial cultures including at least one bacterial strain, wherein the set of bacterial cultures comprises a first subset of one or more bacterial cultures comprising one or more unknown bacterial strain, and a second subset of one or more bacterial cultures comprising one or more known bacterial strains, wherein each of the bacterial strains of the second subset is known; wherein the process is carried out with an initial order of the set of bacterial cultures; wherein during culturing with each bacterial culture of the first subset a process sample is collected, wherein a culture sample of a bacterial culture of the second subset is exposed to the collected process samples in order to determine bacteriophage sensitivities of the one or more bacterial cultures of the second subset to bacteriophages present in the collected process sample, wherein an adapted order of the set of bacterial cultures is determined based on the determined bacteriophage sensitivities such as to reduce common bacteriophage sensitivities in successive bacterial cultures.
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公开(公告)号:US20230048427A1
公开(公告)日:2023-02-16
申请号:US17794346
申请日:2021-01-28
Applicant: DSM IP ASSETS B.V.
Inventor: Pim VAN HEE
IPC: C12N1/20 , A23L3/3463 , A23L33/135 , C12Q1/70
Abstract: A method, system and computer program for selecting consecutive bacterial cultures for culturing a food product in a process for producing a fermented food product, the method comprising the steps of: culturing the food product with a first bacterial culture comprising at least one bacterial strain; isolating a sample during culturing with the first bacterial culture; determining at least one value indicative for a number of bacteriophages in the sample, e.g. using PCR, plaque assay, or pH; selecting a second bacterial culture for culturing the food product when the value is larger than a predetermined threshold, wherein the second bacterial culture comprises at least one bacterial strain, wherein the second bacterial culture differs from the first bacterial culture, wherein the sensitivities of the first and second bacterial culture for the bacteriophages in the sample are known and wherein the second bacterial culture is selected such as to reduce common bacteriophage sensitivities between the first and the second bacterial culture, and culturing the food product with the second bacterial culture.
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公开(公告)号:US20210002389A1
公开(公告)日:2021-01-07
申请号:US17021665
申请日:2020-09-15
Applicant: DSM IP ASSETS B.V.
Inventor: Cornelia Elizabeth Paulina MALJAARS , Pim VAN HEE
IPC: C08B37/00 , C12R1/46 , A23C9/123 , C08L5/00 , C12P19/04 , A23C9/137 , A23C19/032 , A23C19/09 , A23C9/13 , A23C19/05 , C12N1/20
Abstract: The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
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公开(公告)号:US20160257769A1
公开(公告)日:2016-09-08
申请号:US15034231
申请日:2014-11-03
Applicant: DSM IP ASSETS B.V.
Inventor: Cornelia Elizabeth Paulina MALJAARS , Pim VAN HEE
CPC classification number: C08B37/006 , A23C9/123 , A23C9/1238 , A23C9/1307 , A23C9/137 , A23C19/0323 , A23C19/054 , A23C19/09 , A23C2240/00 , A23Y2240/75 , C08L5/00 , C12N1/20 , C12P19/04 , C12R1/46
Abstract: The present invention relates a heteropolysaccharide characterized in that it is substantially composed of the monosaccharides glucose and galactose and rhamnose and N-acetylgalactosamine and a process for the production thereof. The invention further relates to a bacterium capable of producing said heteropolysaccharide and to the use of the heteropolysaccharide and the bacterium for improving the texture of fermented milk products.
Abstract translation: 本发明涉及杂多糖,其特征在于其基本上由单糖葡萄糖和半乳糖,鼠李糖和N-乙酰半乳糖胺组成,并且其生产方法。 本发明还涉及能够生产所述杂多糖的细菌以及杂多糖和细菌用于改善发酵乳制品质地的用途。
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