公开(公告)号：US20220242807A1

公开(公告)日：2022-08-04

申请号：US17613765

申请日：2020-05-26

Applicant: DSM IP ASSETS B.V.

Inventor： Jonathan Alan MEDLOCK ,  Lise Malika MOLINARI

IPC: C07C29/17 ,  B01J23/44 ,  C07F9/50 ,  C07C323/12

Abstract: The present invention relates to a process of hydrogenating an alkyne selectively to an alkene by hydrogen using a hydrogenation catalyst which is palladium supported on a carrier in the presence of an additive mixture of an organic phosphorus compound (AP) and an organic sulphur compound (AS).

公开(公告)号：US20200061587A1

公开(公告)日：2020-02-27

申请号：US16609528

申请日：2018-05-01

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Roman GOY ,  Jonathan Alan MEDLOCK

IPC: B01J23/745 ,  B01J23/755 ,  B01J23/75 ,  B01J23/28 ,  B01J23/26 ,  B01J37/02 ,  B01J23/10 ,  B01J23/44

Abstract: The present invention is related to a new metal powder catalytic system (catalyst), its production and its use in hydrogenation processes.

公开(公告)号：US20180201558A1

公开(公告)日：2018-07-19

申请号：US15742177

申请日：2016-07-14

Applicant: DSM IP ASSETS B.V.

Inventor： Mae Joanne AGUILA ,  Hans Peter HOHMANN ,  Laurent LEFORT ,  Jonathan Alan MEDLOCK ,  Guenter PAPPENBERGER

IPC: C07C29/149 ,  B01J31/24 ,  B01J31/18 ,  B01J31/20

CPC classification number: C07C29/149 ,  B01J31/181 ,  B01J31/189 ,  B01J31/20 ,  B01J31/2409 ,  B01J31/2414 ,  B01J31/2452 ,  B01J2231/48 ,  B01J2531/821 ,  B01J2531/827 ,  C07B2200/07 ,  C07C31/26

Abstract: The present invention relates to a new process for the production of D-sorbitol.

公开(公告)号：US20200123087A1

公开(公告)日：2020-04-23

申请号：US16720580

申请日：2019-12-19

Applicant: DSM IP Assets B.V.

Inventor： Ulla LETINOIS ,  Stephan ACKERMANN ,  Jonathan Alan MEDLOCK ,  Hajo LEHMANN

IPC: C07C41/30 ,  C07C39/08 ,  C07C39/07 ,  B01J31/24 ,  B01J31/22 ,  B01J31/18 ,  C07C43/178 ,  C07C37/50 ,  C07C37/07 ,  C07C41/36 ,  C07C46/08 ,  C07D311/72

Abstract: The present invention relates to a method of preparing ortho substituted phenols from 2,5-dimethylfuran and propargyl ethers in the presence of a gold(I) complex. It is particularly advantageous to use 2,5-dimethylfuran as this offers an ecological beneficial synthesis of said ortho substituted phenols.

公开(公告)号：US20200061573A1

公开(公告)日：2020-02-27

申请号：US16609606

申请日：2018-05-01

Applicant: DSM IP ASSETS B.V.

Inventor： Marco ALTHEIMER ,  Werner BONRATH ,  Roman GOY ,  Jonathan Alan MEDLOCK ,  Sergio VERNUCCIO ,  Philipp RUDOLF VON ROHR

IPC: B01J19/24 ,  B01J19/00 ,  B01D46/24

Abstract: The present invention relates to a device for treatment of material transported through the device having a specific design.

公开(公告)号：US20190144365A1

公开(公告)日：2019-05-16

申请号：US16300269

申请日：2017-05-11

Applicant: DSM IP ASSETS B.V.

Inventor： Matthias BELLER ,  Werner BONRATH ,  Johannes Gerardus DE VRIES ,  Yuting FAN ,  Sandra HÜBNER ,  Laurent LEFORT ,  Jonathan Alan MEDLOCK ,  Pim PUYLAERT ,  Richard VAN HECK

IPC: C07C29/149 ,  B01J31/18 ,  B01J31/22 ,  B01J31/24

CPC classification number: C07C29/149 ,  B01J31/0212 ,  B01J31/1805 ,  B01J31/181 ,  B01J31/226 ,  B01J31/24 ,  B01J31/2404 ,  B01J2231/643 ,  B01J2531/0258 ,  B01J2531/821 ,  B01J2531/825 ,  B01J2531/842 ,  B01J2531/845 ,  C07C31/125 ,  C07C33/14 ,  C07C33/22 ,  C07C33/32 ,  C07C2601/16 ,  C07C31/20

Abstract: The present invention relates to a selective reduction of esters to their corresponding alcohols.

公开(公告)号：US20180201959A1

公开(公告)日：2018-07-19

申请号：US15742094

申请日：2016-07-14

Applicant: DSM IP ASSETS B.V.

Inventor： Mae Joanne AGUILA ,  Hans-Peter HOHMANN ,  Laurent LEFORT ,  Jonathan Alan MEDLOCK ,  Guenter PAPPENBERGER

IPC: C12P7/18 ,  C07C29/149 ,  C12N9/04

CPC classification number: C12P7/18 ,  C07C29/149 ,  C12N9/0006 ,  C12Y101/99028 ,  C07C31/26

Abstract: The present invention relates to a novel and inventive process for the production of sorbitol from D-sucrose.

公开(公告)号：US20160185683A1

公开(公告)日：2016-06-30

申请号：US14652562

申请日：2013-12-18

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Thomas NETSCHER ,  Jonathan Alan MEDLOCK ,  Gerardus Karel Maria VERZIJL ,  Andreas Hendrikus Maria DE VRIES

IPC: C07B35/02 ,  C07C41/48 ,  B01J31/18 ,  C07D317/12 ,  C07D319/06 ,  C07C41/56 ,  C07C41/58

CPC classification number: C07B35/02 ,  B01J31/189 ,  B01J2231/34 ,  B01J2531/827 ,  C07B53/00 ,  C07B2200/07 ,  C07B2200/09 ,  C07C41/48 ,  C07C41/56 ,  C07C41/58 ,  C07D311/72 ,  C07D317/12 ,  C07D319/06 ,  C07C43/303 ,  C07C43/313

Abstract: The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced.

Abstract translation: 本发明涉及在至少一种手性铱络合物的存在下，通过分子氢在不饱和酮或不饱和醛的缩醛中缩酮的不对称氢化的方法。 该方法以非常有效的方式产生手性化合物，并且非常有利的是铱络合物的量可以显着降低。

公开(公告)号：US20150329451A1

公开(公告)日：2015-11-19

申请号：US14647636

申请日：2013-11-28

Applicant: DSM IP ASSETS B.V.

Inventor： Raphael BEUMER ,  Werner BONRATH ,  Jonathan Alan MEDLOCK

IPC: C07C29/17

CPC classification number: C07C29/172 ,  C07C29/10 ,  C07C29/103 ,  C07C31/125

Abstract: The present invention relates to a new and improved synthesis of tetrahydromyrcenol (IUPAC name: 2,6-dimethyl-2-octanol).

Abstract translation: 本发明涉及四氢月桂烯醇（IUPAC名称：2,6-二甲基-2-辛醇）的新的和改进的合成。

公开(公告)号：US20150321986A1

公开(公告)日：2015-11-12

申请号：US14652339

申请日：2013-12-18

Applicant: DSM IP ASSETS B.V.

Inventor： Werner BONRATH ,  Thomas NETSCHER ,  Jonathan Alan MEDLOCK ,  René Tobias STEMMLER ,  Gerardus Karel Maria VERZIJL ,  Andreas Hendrikus Maria DE VRIES

IPC: C07C45/62 ,  C07C50/14 ,  C07D311/58 ,  C07C45/82 ,  C07C43/303

CPC classification number: C07C45/62 ,  C07B2200/07 ,  C07B2200/09 ,  C07C43/303 ,  C07C45/82 ,  C07C50/14 ,  C07D311/58 ,  C07C49/203 ,  C07C49/04 ,  C07C47/02

Abstract: The present invention relates to a process of manufacturing compound having stereogenic centres from a mixture of E/Z isomers of unsaturated compounds having prochiral double bonds. The hydrogenation product has a specific desired configuration at the stereogenic centres. The process involves two asymmetric hydrogenation steps. The process is very advantageous in that it forms the desired chiral product from a mixture of stereoisomers of the starting product in an efficient way.

Abstract translation: 本发明涉及由具有前手性双键的不饱和化合物的E / Z异构体的混合物制造具有立体中心化合物的方法。 氢化产物在立体中心处具有特定的所需构型。 该方法涉及两个不对称氢化步骤。 该方法非常有利，因为它以有效的方式从起始产物的立体异构体的混合物形成所需的手性产物。